Best TWAS P=8.82e-20 · Best GWAS P=4.07e-26 conditioned to 6.51e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | ZFP64 | 0.10 | 0.03 | lasso | 4 | 0.06 | 3.4e-05 | 3.2 | 9.1 | 8.8e-20 | -0.75 | 0.01 | 0.98 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | ZFP64 | 0.09 | 0.09 | enet | 5 | 0.09 | 1.9e-07 | -2.5 | 6.0 | 1.7e-09 | -0.42 | 0.77 | 0.15 | FALSE |
| 3 | YFS | Blood | TSHZ2 | 0.10 | 0.03 | bslmm | 798 | 0.07 | 2.8e-22 | -9.2 | 7.5 | 7.6e-14 | -0.64 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | SALL4 | 0.05 | 0.00 | blup | 52 | 0.02 | 7.9e-04 | 2.5 | -5.1 | 3.1e-07 | -0.03 | 0.01 | 0.16 | TRUE |