Best TWAS P=8.99e-12 · Best GWAS P=5.74e-14 conditioned to 0.524
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ARFGEF2 | 0.09 | 0.05 | lasso | 8 | 0.10 | 9.2e-13 | -6.6 | 6.5 | 9.7e-11 | -0.41 | 0.49 | 0.51 | TRUE |
| 2 | CommonMind | Brain Pre-frontal Cortex | STAU1 | 0.09 | 0.00 | bslmm | 500 | 0.01 | 8.7e-03 | 1.2 | 5.9 | 4.4e-09 | -0.54 | 0.02 | 0.93 | TRUE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | ZFAS1 | 0.16 | 0.04 | enet | 19 | 0.07 | 1.0e-04 | -2.8 | -5.3 | 1.5e-07 | 0.48 | 0.17 | 0.63 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | ZFAS1 | 0.07 | 0.03 | enet | 14 | 0.05 | 5.8e-05 | -6.0 | -6.8 | 9.0e-12 | 0.55 | 0.56 | 0.26 | TRUE |
| 5 | GTEx | Testis | ARFGEF2 | 0.20 | 0.20 | lasso | 7 | 0.24 | 5.4e-11 | -3.8 | 5.4 | 7.6e-08 | -0.51 | 0.87 | 0.13 | FALSE |
| 6 | METSIM | Adipose | ARFGEF2 | 0.04 | 0.03 | lasso | 12 | 0.02 | 9.8e-05 | -6.3 | 5.9 | 3.7e-09 | -0.50 | 0.73 | 0.16 | FALSE |
| 7 | NTR | Blood | SNORD12B | 0.03 | 0.05 | lasso | 8 | 0.05 | 1.9e-14 | -6.0 | 6.1 | 1.4e-09 | -0.51 | 0.96 | 0.04 | TRUE |
| 8 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARFGEF2 | 0.05 | 0.04 | lasso | 5 | 0.05 | 3.2e-06 | -6.6 | 6.2 | 5.4e-10 | -0.58 | 0.51 | 0.49 | FALSE |
| 9 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | C20orf199 | 0.05 | 0.06 | lasso | 4 | 0.06 | 1.0e-04 | -5.9 | -5.9 | 3.8e-09 | 0.51 | 0.01 | 0.96 | FALSE |