Best TWAS P=5.56e-14 · Best GWAS P=6.28e-21 conditioned to 1e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ADARB1 | 0.12 | 0.03 | blup | 656 | 0.03 | 3.6e-04 | -5.3 | -7.0 | 2.7e-12 | 0.51 | 0.29 | 0.66 | TRUE |
| 2 | GTEx | Artery Tibial | POFUT2 | 0.07 | 0.01 | enet | 11 | 0.03 | 1.6e-03 | 3.0 | -5.4 | 7.0e-08 | 0.50 | 0.85 | 0.01 | FALSE |
| 3 | GTEx | Brain Cerebellar Hemisphere | BX322557.10 | 0.35 | 0.24 | lasso | 9 | 0.26 | 2.4e-07 | 4.1 | -5.3 | 1.0e-07 | 0.58 | 0.80 | 0.13 | FALSE |
| 4 | GTEx | Muscle Skeletal | PTTG1IP | 0.07 | 0.01 | enet | 6 | 0.00 | 9.7e-02 | -8.3 | 7.2 | 4.6e-13 | -0.71 | 0.01 | 0.89 | FALSE |
| 5 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | ADARB1 | 0.07 | 0.01 | blup | 139 | 0.04 | 4.5e-03 | 6.7 | -7.5 | 5.6e-14 | 0.83 | 0.01 | 0.90 | TRUE |
| 6 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | C21orf122 | 0.05 | 0.04 | lasso | 3 | 0.04 | 6.5e-05 | 7.3 | -7.2 | 7.3e-13 | 0.60 | 0.00 | 1.00 | FALSE |
| 7 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | C21orf122 | 0.20 | 0.04 | lasso | 6 | 0.08 | 2.6e-04 | 7.3 | -7.0 | 3.5e-12 | 0.57 | 0.00 | 0.99 | FALSE |