[Hub]/) : Traits : BMI : ← →

chr2:97,098,095-98,975,985

Best TWAS P=1.16e-11 · Best GWAS P=1.43e-08 conditioned to 0.582

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	ACTR1B	0.29	0.15	enet	10	0.19	1.1e-15	5.6	6.5	5.9e-11	0.68	0.00	1.00	FALSE
2	GTEx	Adipose Visceral Omentum	ACTR1B	0.26	0.17	lasso	4	0.18	9.6e-10	5.6	6.7	2.5e-11	0.69	0.00	1.00	FALSE
3	GTEx	Artery Aorta	ACTR1B	0.16	0.18	enet	4	0.16	2.6e-09	5.6	6.2	6.0e-10	0.68	0.00	1.00	FALSE
4	GTEx	Artery Tibial	ACTR1B	0.31	0.25	lasso	5	0.34	4.8e-27	5.6	5.7	1.0e-08	0.63	0.00	1.00	FALSE
5	GTEx	Brain Cerebellum	ACTR1B	0.36	0.38	lasso	2	0.38	3.6e-12	5.6	5.6	2.6e-08	0.69	0.00	1.00	FALSE
6	GTEx	Colon Transverse	ACTR1B	0.17	0.14	lasso	3	0.15	1.9e-07	5.6	5.7	9.8e-09	0.69	0.00	1.00	FALSE
7	GTEx	Esophagus Muscularis	ACTR1B	0.27	0.18	lasso	3	0.25	2.9e-15	5.6	5.7	1.5e-08	0.64	0.00	1.00	FALSE
8	GTEx	Lung	ACTR1B	0.20	0.13	lasso	1	0.12	2.4e-09	5.6	5.6	2.4e-08	0.69	0.00	1.00	FALSE
9	GTEx	Nerve Tibial	ACTR1B	0.42	0.19	enet	11	0.23	2.3e-16	5.6	6.8	1.2e-11	0.78	0.00	1.00	TRUE
10	GTEx	Pancreas	ACTR1B	0.09	0.09	enet	26	0.08	2.0e-04	5.7	5.6	1.7e-08	0.73	0.00	0.96	FALSE
11	GTEx	Pituitary	ACTR1B	0.68	0.50	lasso	3	0.49	4.8e-14	5.6	5.5	3.2e-08	0.68	0.00	1.00	FALSE
12	GTEx	Skin Sun Exposed Lower leg	ACTR1B	0.13	0.11	enet	10	0.11	1.4e-09	5.6	5.7	1.6e-08	0.72	0.00	1.00	FALSE
13	GTEx	Spleen	ACTR1B	0.25	0.32	lasso	2	0.30	1.9e-08	5.6	6.0	2.3e-09	0.67	0.00	0.99	FALSE
14	GTEx	Testis	ACTR1B	0.23	0.21	lasso	1	0.20	4.1e-09	5.6	5.6	2.4e-08	0.69	0.00	1.00	FALSE
15	GTEx	Thyroid	ACTR1B	0.48	0.33	lasso	2	0.32	1.8e-25	5.6	5.6	2.8e-08	0.69	0.00	1.00	FALSE
16	GTEx	Vagina	ACTR1B	0.34	0.01	enet	7	0.00	3.9e-01	5.6	6.2	4.1e-10	0.62	0.01	0.74	FALSE
17	GTEx	Whole Blood	ACTR1B	0.09	0.04	lasso	3	0.04	1.7e-04	5.6	6.6	3.9e-11	0.83	0.00	1.00	FALSE
18	METSIM	Adipose	ACTR1B	0.18	0.14	lasso	7	0.16	2.0e-22	5.7	6.1	1.1e-09	0.92	0.00	1.00	FALSE
19	METSIM	Adipose	ANKRD36	0.07	0.04	lasso	5	0.04	1.2e-06	5.6	6.4	1.2e-10	0.80	0.00	1.00	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	ACTR1B	0.27	0.17	bslmm	137	0.19	1.8e-23	5.6	5.7	1.0e-08	0.70	0.00	1.00	FALSE