Best TWAS P=4.52e-09 · Best GWAS P=6.34e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | PPIP5K2 | 0.07 | 0.04 | enet | 22 | 0.05 | 1.4e-04 | 4.8 | -5.7 | 1.5e-08 | -0.75 | 0.12 | 0.87 | FALSE |
| 2 | GTEx | Colon Sigmoid | PPIP5K2 | 0.14 | 0.00 | enet | 17 | 0.04 | 1.9e-02 | 4.3 | -5.5 | 3.0e-08 | -0.59 | 0.37 | 0.33 | FALSE |
| 3 | GTEx | Thyroid | PAM | 0.07 | 0.08 | lasso | 4 | 0.07 | 5.5e-06 | 5.8 | -5.9 | 4.5e-09 | -0.99 | 0.01 | 0.99 | TRUE |
| 4 | GTEx | Whole Blood | PAM | 0.20 | 0.28 | lasso | 9 | 0.27 | 1.0e-24 | 5.1 | 5.3 | 1.0e-07 | 0.84 | 0.15 | 0.85 | FALSE |