Hub : Genes

PPIP5K2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.0740 0.0250 6.9e-08 0.101 NA 0.098 NA 0.115 1.4e-08 NA 2.1e-08 NA 1.2e-09
2 GTEx Adrenal Gland 0.1563 0.0525 1.2e-06 0.169 NA 0.157 NA 0.178 1.2e-06 NA 3.0e-06 NA 5.9e-07
3 GTEx Artery Aorta 0.0800 0.0340 1.4e-04 0.072 NA 0.057 NA 0.069 8.6e-05 NA 4.2e-04 NA 1.2e-04
4 GTEx Artery Tibial 0.0666 0.0256 1.2e-05 0.045 NA 0.047 NA 0.043 1.9e-04 NA 1.4e-04 NA 2.6e-04
5 GTEx Brain Nucleus accumbens basal ganglia 0.1860 0.0810 8.5e-04 0.061 NA 0.051 NA 0.037 1.0e-02 NA 1.7e-02 NA 3.6e-02
6 GTEx Breast Mammary Tissue 0.1090 0.0500 1.8e-04 0.104 NA 0.040 NA 0.044 5.2e-06 NA 4.0e-03 NA 2.7e-03
7 GTEx Breast Mammary Tissue (Female) 0.0855 0.0416 5.3e-03 0.014 NA 0.000 NA 0.001 1.2e-01 NA 3.3e-01 NA 2.9e-01
8 GTEx Cells EBV-transformed lymphocytes 0.3710 0.0800 1.4e-11 0.321 NA 0.368 NA 0.363 3.7e-11 NA 6.6e-13 NA 1.0e-12
9 GTEx Colon Sigmoid 0.1370 0.0580 2.1e-04 0.004 NA 0.036 NA 0.027 2.3e-01 NA 2.0e-02 NA 3.8e-02
10 GTEx Esophagus Gastroesophageal Junction 0.1350 0.0670 2.1e-03 0.088 NA 0.019 NA 0.030 4.5e-04 NA 6.5e-02 NA 3.0e-02
11 GTEx Esophagus Muscularis 0.0530 0.0250 1.3e-03 0.024 NA 0.026 NA 0.022 1.3e-02 NA 9.8e-03 NA 1.7e-02
12 GTEx Nerve Tibial 0.1108 0.0402 8.1e-07 0.127 NA 0.100 NA 0.106 3.0e-09 NA 1.4e-07 NA 6.5e-08
13 GTEx Pituitary 0.1510 0.0810 2.3e-03 0.102 NA 0.107 NA 0.100 1.6e-03 NA 1.2e-03 NA 1.7e-03
14 GTEx Small Intestine Terminal Ileum 0.3290 0.1130 1.7e-03 -0.006 NA 0.001 NA -0.009 4.6e-01 NA 3.0e-01 NA 5.9e-01
15 GTEx Spleen 0.1800 0.0630 3.0e-05 0.193 NA 0.193 NA 0.187 1.1e-05 NA 1.1e-05 NA 1.5e-05
16 GTEx Stomach 0.0540 0.0300 8.5e-03 0.039 NA 0.007 NA 0.035 6.0e-03 NA 1.5e-01 NA 8.7e-03
17 GTEx Whole Blood 0.1350 0.0440 7.8e-07 0.057 NA 0.053 NA 0.076 5.7e-06 NA 1.3e-05 NA 1.6e-07
18 METSIM Adipose 0.0548 0.0186 5.0e-10 0.067 0.072 0.063 0.071 0.060 2.8e-10 6.3e-11 9.9e-10 9.5e-11 2.1e-09
19 NTR Blood 0.0297 0.0089 6.6e-12 0.044 0.041 0.044 0.040 0.043 6.4e-14 3.4e-13 5.3e-14 5.0e-13 7.3e-14
20 TCGA Bladder Urothelial Carcinoma 0.0260 0.0190 2.3e-03 0.033 0.028 0.029 NA 0.030 7.4e-04 1.8e-03 1.5e-03 NA 1.3e-03
21 TCGA Breast Invasive Carcinoma 0.0095 0.0067 2.4e-03 0.014 0.013 0.012 NA 0.012 6.7e-04 9.3e-04 1.4e-03 NA 1.1e-03
22 TCGA Cervical Squamous Cell Carcinoma 0.1570 0.0930 6.7e-04 0.031 0.028 0.039 NA 0.046 1.2e-02 1.5e-02 5.1e-03 NA 2.6e-03
23 TCGA Colon Adenocarcinoma 0.0540 0.0440 2.2e-03 0.032 0.030 0.022 NA 0.021 6.0e-03 7.1e-03 1.8e-02 NA 2.2e-02
24 TCGA Head and Neck Squamous Cell Carcinoma 0.0393 0.0241 1.8e-06 0.043 0.048 0.026 NA 0.044 1.2e-05 4.1e-06 5.4e-04 NA 8.7e-06
25 TCGA Liver Hepatocellular Carcinoma 0.0450 0.0340 3.5e-03 0.031 0.033 0.015 NA 0.022 1.4e-02 1.0e-02 6.2e-02 NA 3.3e-02
26 TCGA Prostate Adenocarcinoma 0.1011 0.0563 4.7e-03 0.001 0.001 0.029 NA 0.007 2.4e-01 2.5e-01 5.0e-04 NA 5.8e-02
27 TCGA Testicular Germ Cell Tumors 0.2640 0.1220 6.3e-09 0.212 0.130 0.219 NA 0.230 5.2e-08 2.6e-05 2.8e-08 NA 1.2e-08

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bipolar Disorder (2018) 1.3 2.0 4.8 1.5 1.4 1.3 1.2 1.4 1.4 1.5 -1.4 1.0 1.0 1.6 1.3 1.1 1.1 -1.6 1.2 2.2 1.4 1.6 -1.6 -1.6 0.0 -1.6 -1.4 -1.4 -1.1 -1.8
Bipolar Disorder or Schizophrenia 0.0 0.1 0.4 0.1 0.0 0.0 0.5 0.3 0.1 0.2 -0.4 -0.5 -0.3 0.2 0.0 0.1 -0.7 -0.5 0.2 0.2 0.0 0.3 -0.3 -0.4 0.0 -0.2 -0.1 -0.1 0.1 -0.6
Depressed Affect (Nagel 2018) 0.1 0.2 1.1 0.2 0.4 0.2 0.0 0.1 0.9 0.6 -0.3 0.3 0.9 0.5 0.3 0.6 1.1 -0.1 0.3 1.0 -0.5 0.1 -0.2 -0.3 -0.3 0.0 0.0 0.0 0.7 -0.2
Depression (Nagel 2018) 1.0 1.5 4.2 -1.1 -0.9 -0.9 -1.2 -1.5 -0.3 -0.8 1.5 -1.4 0.3 -0.9 -0.8 -0.4 1.3 1.6 -0.9 -0.2 -1.5 -1.3 1.5 1.2 1.5 1.5 1.5 1.5 2.0 1.2
Intelligence (Savage-Jansen 2018) 2.8 8.5 17.2 -3.2 -2.9 -3.3 -2.2 -3.0 -2.6 -3.0 3.4 -1.8 -2.2 -2.8 -3.2 -4.1 -1.7 3.7 -3.2 -3.3 -2.4 -3.2 3.2 3.5 0.0 2.9 2.7 2.7 -0.2 4.0
Neuroticism (Nagel 2018) 1.8 4.3 7.7 2.1 2.3 2.3 1.2 2.0 2.6 2.5 -1.5 2.0 2.6 2.4 2.3 2.8 2.6 -1.8 2.1 2.6 1.0 1.9 -2.0 -2.1 -1.6 -1.6 -1.7 -1.8 1.2 -2.1
Schizophrenia (2018) 0.5 1.0 2.5 -1.0 -1.1 -1.0 -0.3 -0.8 -0.9 -1.0 0.6 -1.5 -1.0 -1.1 -1.1 -0.7 -1.6 0.7 -0.7 -1.5 -1.1 -0.9 0.9 0.9 0.0 0.9 1.0 1.0 0.5 0.7
Schizophrenia vs Biploar Disorder 1.0 1.3 2.6 -1.3 -1.2 -1.4 -0.6 -1.2 -0.7 -0.9 0.9 -0.9 -0.8 -1.2 -1.4 -1.2 -0.8 1.5 -1.2 -1.1 -1.6 -1.3 1.4 1.4 0.0 1.1 1.2 1.2 -0.6 1.6
Worry (Nagel 2018) 9.4 19.8 30.9 4.9 5.0 5.1 2.4 4.5 4.8 4.8 -4.2 4.0 4.7 5.0 5.1 5.6 3.5 -4.5 4.8 4.9 3.5 4.8 -4.6 -4.8 -3.1 -4.3 -4.4 -4.3 0.3 -5.0
Alzheimer’s Disease (in mother) 0.2 0.2 0.8 -0.4 -0.4 -0.2 -0.4 -0.6 -0.1 -0.1 0.8 0.2 -0.2 -0.4 -0.1 -0.4 -0.6 0.4 -0.6 -0.3 -0.7 -0.5 0.3 0.4 -0.6 0.5 0.4 0.3 0.5 0.9
Alzheimer’s Disease (in father) 0.6 0.7 8.3 0.2 0.3 0.6 0.4 -0.6 0.9 0.4 -0.4 0.9 1.3 0.5 0.7 0.6 1.8 0.2 -0.2 -0.2 -0.5 -0.2 0.0 0.1 -0.2 0.6 0.2 0.1 2.9 0.1
Alzheimer’s Disease (including proxy) 0.8 1.2 6.1 -0.9 -0.9 -0.6 -0.7 -1.4 -0.5 -0.7 1.1 -0.1 -0.4 -0.7 -0.5 -0.9 -0.4 1.1 -1.3 -1.3 -1.6 -1.3 1.0 1.1 -0.0 1.6 1.1 1.1 2.5 1.6
Crohns Disease (2017) 0.2 0.4 1.1 0.8 0.8 1.0 -0.1 0.1 0.6 0.6 -0.7 0.2 0.8 0.7 1.0 1.1 0.6 -0.4 0.5 0.6 0.1 0.6 -0.5 -0.6 -0.1 -0.5 -0.5 -0.4 0.9 -0.6
Irritable Bowel Disease (IBD) 1.0 2.3 4.5 1.6 1.8 1.8 1.3 1.1 2.1 2.0 -1.6 1.5 1.9 1.9 1.8 1.9 2.1 -1.0 1.3 1.4 1.4 1.2 -1.3 -1.4 -0.9 -1.1 -1.2 -1.2 1.0 -1.3
Ulcerative Colitis (UC) 1.3 2.4 5.2 1.5 1.8 1.5 1.4 1.5 2.3 2.1 -1.8 1.8 1.9 1.9 1.5 1.6 2.1 -1.1 1.3 1.3 1.8 1.1 -1.4 -1.4 -1.0 -1.2 -1.3 -1.3 0.4 -1.4
Major Depression (MDD) 0.3 0.4 0.8 -0.8 -0.6 -0.9 -0.3 -0.6 -0.3 -0.2 0.6 -0.1 -0.6 -0.7 -0.9 -0.6 -0.6 0.8 -0.7 -0.3 -0.5 -0.8 0.6 0.7 0.0 0.7 0.8 0.8 0.2 0.5
Reaction Time 0.6 1.2 2.6 -1.1 -1.0 -1.0 -1.5 -1.5 -1.5 -1.1 0.5 -0.3 -1.6 -0.9 -1.0 -0.9 0.3 1.4 -0.8 -0.8 -1.2 -1.2 1.2 1.1 0.8 1.2 1.2 1.2 0.6 1.3
Verbal and Numeric Reasoning (VNR) 5.6 13.4 19.4 -4.0 -3.5 -4.0 -3.1 -4.0 -3.3 -3.6 4.3 -3.0 -2.8 -3.6 -3.9 -4.3 -1.6 4.4 -4.0 -3.9 -3.2 -4.1 3.9 4.1 3.7 3.9 3.9 3.8 1.5 3.5
Breast Cancer 0.4 1.1 2.1 -1.2 -1.2 -1.1 -0.0 -1.1 -1.1 -1.2 1.3 -0.7 -1.1 -1.1 -1.1 -1.4 -0.1 1.4 -1.2 -0.9 -0.5 -1.2 1.0 1.2 0.8 1.0 0.9 0.9 -0.0 1.1
Ovarian Cancer 0.3 0.4 3.6 -0.5 -0.7 -0.7 -0.2 0.0 -0.5 -0.4 0.6 -1.9 -0.7 -0.7 -0.7 -0.6 -0.5 0.4 -0.2 0.0 -0.2 -0.3 0.4 0.3 0.5 0.2 0.5 0.6 -0.9 0.2
Prostate Cancer 0.5 0.7 2.0 -0.9 -0.9 -0.7 -0.3 -0.8 -0.7 -0.8 0.9 0.1 -0.5 -0.8 -0.7 -1.0 0.8 1.1 -0.8 -0.3 -1.3 -0.9 1.0 1.2 0.5 1.0 0.7 0.6 0.3 1.4
Age at First Birth 0.3 0.4 0.9 -0.6 -0.5 -0.5 -0.3 -0.3 -0.5 -0.7 0.9 -0.6 -0.1 -0.7 -0.6 -0.6 -0.9 0.8 -0.5 -0.9 -0.3 -0.7 0.6 0.7 0.0 0.7 0.6 0.5 0.6 0.7
Bipolar Disorder (2011) 0.2 0.1 1.1 -0.3 -0.2 -0.3 -1.0 -0.3 -0.6 -0.3 -0.3 -0.2 -0.9 -0.0 -0.3 -0.4 0.5 0.3 -0.3 0.4 -0.3 -0.4 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.7 1.0 4.2 -1.1 -1.1 -1.5 -0.4 -0.8 -1.3 -1.1 0.4 -0.9 -2.1 -1.0 -1.5 -1.1 -0.9 0.9 -0.8 -1.2 -1.0 -0.9 1.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0
Coronary Artery Disease (CAD) 2.3 2.7 6.2 2.0 1.7 1.6 0.8 2.5 1.1 1.4 -1.9 0.6 1.0 1.7 1.6 2.0 0.6 -2.2 1.8 1.7 1.4 1.9 -2.0 -2.0 0.0 -1.8 -1.6 -1.6 -0.8 -2.3
Crohns Disease (2012) 1.1 1.8 2.8 -1.4 -1.3 -1.3 -1.2 -1.7 -1.2 -1.4 1.4 -1.2 -1.1 -1.4 -1.3 -1.1 -0.2 1.6 -1.7 -0.7 -1.5 -1.4 1.4 1.3 0.0 1.5 1.6 1.6 1.4 1.1
Mean Putamen Volume 0.7 0.8 3.6 -0.9 -0.7 -0.9 -0.5 -0.9 -0.7 -0.8 0.6 -0.1 -0.7 -0.7 -1.0 -1.0 -1.3 0.7 -0.8 -1.9 -0.6 -1.1 0.9 0.9 0.0 0.9 0.9 0.9 0.3 0.9
Fasting Glucose 1.5 1.8 4.2 1.5 1.5 1.1 1.7 1.6 1.5 1.6 -1.1 1.3 1.2 1.5 1.1 1.6 0.8 -1.6 1.4 1.1 1.1 1.7 -1.6 -1.6 0.0 -1.3 -1.1 -1.1 0.5 -2.0
HbA1C 2.1 2.3 3.7 -1.9 -1.7 -1.8 -1.1 -1.5 -1.6 -1.7 1.7 -0.9 -1.7 -1.8 -1.8 -1.7 -1.0 1.9 -1.6 -1.5 -1.0 -1.7 1.6 1.6 0.0 1.4 1.3 1.3 -0.1 1.9
HDL Cholesterol 0.6 1.1 2.7 1.3 1.2 1.1 0.3 1.6 0.7 1.0 -1.3 0.4 0.7 1.1 1.0 1.2 0.2 -1.3 1.5 1.5 1.3 1.2 -1.5 0.0 0.0 0.0 -1.5 0.0 0.0 0.0
LDL Cholesterol 1.9 2.9 8.8 1.9 1.8 1.7 3.0 1.9 2.6 2.0 -1.7 1.7 2.6 2.1 2.0 1.9 0.5 -1.9 1.4 1.6 2.0 1.9 -1.6 0.0 0.0 0.0 -1.8 0.0 0.0 0.0
Lupus 3.1 4.6 6.8 2.1 2.5 2.2 1.4 2.1 2.2 2.2 -2.6 2.3 2.1 2.1 2.2 2.3 1.6 -1.9 2.5 2.6 1.8 2.5 -2.2 -2.3 0.0 -2.5 -2.2 -2.2 -1.4 -2.5
Neuroticism (2016) 2.9 4.2 7.7 2.3 2.2 2.4 1.4 2.2 1.9 2.0 -2.1 2.1 2.1 2.1 2.4 2.6 2.8 -1.9 2.6 2.3 1.4 1.9 -2.0 -2.2 0.0 -1.9 -2.1 -2.1 0.3 -2.0
Primary Biliary Cirrhosis 2.8 4.0 8.5 2.2 2.4 2.3 0.8 1.6 1.9 1.9 -2.9 1.7 1.8 2.3 2.2 2.8 1.8 -2.1 2.5 2.4 0.9 2.2 -2.0 -2.2 0.0 -1.9 -1.8 -1.8 0.4 -2.4
Rheumatoid Arthritis 8.5 11.7 18.2 3.6 3.7 3.7 3.6 3.3 3.8 4.0 -4.2 2.6 3.1 3.6 3.5 4.2 3.1 -3.6 3.9 3.2 2.5 3.6 -3.7 -3.8 0.0 -3.3 -3.2 -3.2 0.0 -4.3
Schizophrenia (2014) 0.3 0.7 1.5 -1.0 -0.9 -1.0 -0.1 -1.0 -0.4 -0.6 0.5 -0.6 -0.5 -0.7 -1.0 -0.7 -1.0 0.8 -0.7 -1.2 -1.1 -0.7 0.9 0.9 0.0 0.9 1.0 1.0 0.4 0.7
Triglycerides 0.3 0.4 1.5 -1.0 -0.9 -0.5 0.2 -0.9 0.1 -0.4 1.2 -0.4 -0.0 -0.5 -0.6 -0.6 -0.6 0.9 -1.0 -1.1 -1.0 -0.9 0.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0
Type 2 Diabetes (T2D) (2012) 3.2 3.7 10.4 -1.8 -1.9 -1.9 -3.2 -1.9 -2.8 -2.6 2.3 -2.5 -2.4 -2.0 -2.0 -1.9 -2.8 1.6 -2.0 -2.5 -1.8 -1.8 1.5 0.0 0.0 0.0 1.5 0.0 0.0 0.0
Ulcerative Colitis 0.2 0.3 2.6 0.1 0.3 0.2 0.3 -0.1 1.0 0.8 -0.6 0.7 0.9 0.5 0.3 0.2 1.6 0.2 -0.1 -0.1 0.2 -0.1 0.1 -0.0 0.0 0.0 0.0 0.0 0.7 -0.1
Blood Eosinophil Count 0.3 1.9 4.6 1.2 1.2 1.1 1.9 1.0 1.1 1.6 -1.7 0.2 0.4 1.3 1.0 1.1 2.1 -1.4 1.4 1.9 0.6 1.8 -1.4 -1.6 -1.4 -1.7 -1.2 -1.1 -2.1 -1.1
Blood Platelet Count 1.0 11.7 15.2 3.8 3.6 3.6 3.8 3.5 3.5 3.9 -3.8 3.2 2.9 3.8 3.6 3.3 1.3 -3.7 3.7 1.8 3.4 3.7 -3.6 -3.7 -2.3 -3.9 -3.8 -3.7 -1.6 -3.8
Blood Red Count 2.0 19.5 32.5 4.8 4.7 4.5 2.6 4.4 3.7 4.5 -5.7 3.4 2.8 4.6 4.6 5.0 2.4 -4.9 5.1 4.1 3.7 4.9 -5.1 -5.1 -4.6 -5.0 -4.8 -4.8 -2.3 -4.8
Blood White Count 2.5 18.7 35.6 -4.1 -4.6 -4.3 -6.0 -4.5 -5.2 -5.2 4.6 -4.5 -4.5 -4.8 -4.1 -4.2 -4.3 4.3 -4.3 -3.6 -5.2 -3.4 4.3 4.2 3.7 3.4 3.8 3.9 -1.2 4.6
Heel T-Score 0.2 1.6 4.5 -1.3 -1.3 -1.4 -1.0 -1.1 -1.6 -1.5 1.4 -1.0 -1.7 -1.4 -1.4 -2.0 -1.2 1.4 -1.1 -1.0 -0.9 -0.8 1.1 1.4 0.9 0.6 0.7 0.7 -2.1 1.2
BMI 2.4 13.6 32.1 -3.5 -3.9 -3.6 -5.7 -3.5 -5.0 -4.8 3.5 -5.5 -4.4 -4.6 -3.6 -2.9 -1.8 3.5 -3.4 -1.5 -3.5 -2.7 3.5 3.1 2.4 3.0 3.8 4.0 -0.4 3.8
Height 2.6 49.9 63.3 7.6 8.0 7.8 4.9 7.0 7.8 7.5 -7.3 6.8 7.5 7.7 7.7 7.8 3.8 -7.4 7.6 6.8 6.9 6.8 -7.7 -7.7 -7.4 -6.8 -7.2 -7.2 -0.4 -7.1
Waist Hip Ratio (WHR) 10.9 49.1 65.4 7.4 7.5 7.4 7.1 6.3 8.1 7.8 -7.3 7.4 7.6 7.7 7.5 7.6 5.3 -7.0 7.1 6.4 6.7 7.1 -7.3 -7.3 -6.8 -6.9 -7.0 -7.0 -1.2 -6.5
Systolic Blood Pressure 0.6 3.2 5.7 2.3 1.9 2.0 0.8 2.2 1.2 1.6 -2.1 0.9 1.2 1.7 2.1 2.2 -0.5 -2.1 2.0 1.5 1.9 2.0 -2.1 -2.2 -1.4 -1.9 -2.0 -2.0 0.3 -2.4
Smoking Status 1.0 2.4 5.2 -1.6 -1.2 -1.6 -1.6 -2.3 -0.9 -1.4 1.2 -0.9 -1.0 -1.5 -1.7 -1.4 -0.0 1.9 -1.3 -1.6 -1.9 -1.5 2.0 1.8 2.0 1.6 1.7 1.7 0.4 1.8
Allergy or Eczema 1.7 4.5 9.9 2.1 2.1 2.0 1.3 1.7 1.7 2.1 -2.6 0.5 1.0 1.7 2.1 2.9 1.2 -2.5 2.3 3.1 1.9 3.1 -2.1 -2.5 -1.7 -2.7 -1.9 -1.7 -2.3 -2.0
Cardiovascular Disease 0.1 0.3 2.5 0.5 -0.2 0.1 -1.1 0.0 -0.7 -0.1 -0.4 -1.6 -0.6 -0.3 0.2 0.6 0.8 -0.2 0.2 1.1 -0.3 0.5 -0.3 -0.5 -0.1 -0.3 -0.1 -0.1 0.5 -0.6
Hypothyroidism (self reported) 7.1 16.4 29.5 4.6 4.2 4.7 2.8 4.2 3.6 4.2 -4.5 2.6 3.2 4.0 4.7 5.4 2.2 -4.7 4.6 4.4 3.1 4.7 -4.3 -4.8 -3.2 -4.4 -3.9 -3.8 -0.6 -4.5
Respiratory disease 0.3 0.7 1.4 0.7 1.1 0.7 0.6 0.9 1.1 1.0 -0.9 0.5 0.9 0.9 0.7 1.2 -0.1 -0.9 1.0 0.7 0.7 1.2 -0.8 -1.0 -0.7 -1.0 -0.6 -0.5 -1.0 -0.6
Type 2 Diabetes (T2D) (2018) 9.9 18.5 24.2 -4.5 -4.7 -4.6 -4.3 -4.6 -4.8 -4.7 4.4 -4.2 -4.3 -4.9 -4.6 -4.6 -2.1 4.6 -4.2 -4.0 -4.0 -4.4 4.6 4.6 4.3 4.3 4.3 4.3 1.0 4.2
Lung FEV1/FVC ratio 2.1 10.9 21.9 -3.3 -3.4 -3.4 -4.0 -3.2 -3.8 -3.6 3.1 -4.7 -3.7 -3.8 -3.4 -3.0 -2.2 3.1 -3.2 -2.6 -4.1 -2.6 3.3 3.0 3.4 2.7 3.3 3.5 -0.5 2.8
Lung FVC 0.8 3.8 10.8 -2.3 -2.0 -2.1 -0.9 -2.3 -1.6 -1.8 2.5 -0.5 -1.5 -1.7 -2.2 -3.3 -1.2 2.2 -2.2 -2.1 -1.5 -2.4 2.1 2.5 2.1 2.0 1.6 1.5 -0.3 1.8
Neuroticism 3.0 7.3 10.9 2.9 3.0 2.9 1.9 2.7 3.3 3.1 -2.7 2.4 2.9 3.1 2.9 3.3 1.9 -2.6 2.8 3.2 1.9 2.8 -2.8 -3.0 -2.5 -2.6 -2.5 -2.5 0.1 -2.8
Chronotype (morning person) 0.2 0.4 3.5 -0.3 -0.6 -0.3 -1.9 -0.2 -0.8 -0.5 0.5 -0.9 -0.7 -0.8 -0.3 0.1 0.1 0.3 -0.3 -0.1 -1.0 -0.6 -0.0 0.0 -0.5 0.4 0.4 0.4 0.7 0.2
Hair Pigment 0.0 0.2 1.4 -0.3 -0.0 -0.3 -0.2 -0.3 0.1 -0.1 -0.4 -0.6 0.1 -0.4 -0.3 0.6 1.2 0.2 0.4 0.3 -0.5 -0.1 0.2 -0.1 0.7 0.3 0.7 0.7 1.2 -0.5
Tanning 0.6 7.4 12.5 -2.8 -2.7 -2.8 -3.5 -2.9 -2.9 -3.4 2.8 -2.8 -2.5 -3.0 -2.8 -2.2 -2.8 2.4 -2.7 -2.4 -3.3 -2.4 2.8 2.5 2.3 2.5 2.9 3.0 0.2 2.7
Hand grip strength (left) 3.2 8.5 13.2 3.4 2.9 3.3 0.4 3.1 2.2 2.3 -2.6 1.4 2.4 2.8 3.3 3.2 0.5 -3.5 2.9 3.3 3.3 3.1 -3.5 -3.4 -3.6 -3.3 -3.5 -3.5 -1.4 -2.9
Number of treatments/medications taken 1.1 2.1 4.6 1.6 1.3 1.6 0.7 1.7 1.0 1.4 -1.7 0.9 0.9 1.0 1.6 2.1 1.5 -1.4 2.0 1.9 1.1 1.6 -1.5 -1.7 -1.1 -1.4 -1.2 -1.2 0.2 -1.7
Average weekly spirits intake 0.2 0.2 0.8 -0.5 -0.6 -0.6 -0.3 -0.3 -0.4 -0.1 0.1 -0.7 -0.7 -0.9 -0.6 -0.2 0.3 0.6 -0.0 -0.1 -0.2 -0.4 0.3 0.3 -0.0 0.3 0.5 0.5 -0.3 0.4
Sensitivity / hurt feelings 1.3 2.2 3.7 1.6 1.5 1.7 1.9 1.5 1.8 1.7 -0.7 1.2 1.8 1.7 1.7 1.8 1.1 -1.5 1.3 1.6 0.8 1.4 -1.5 -1.6 -0.8 -1.3 -1.3 -1.3 0.8 -1.9
Frequency of depressed mood in last 2 weeks 0.4 0.6 4.0 -0.3 -0.1 -0.2 -0.8 -0.6 0.3 -0.1 0.4 -0.5 1.1 -0.2 -0.1 0.2 2.0 0.8 -0.1 -0.1 -0.7 -0.3 0.9 0.5 1.0 0.9 0.9 0.9 2.0 0.6
Hearing difficulty/problems: Yes 1.1 1.6 4.2 -1.4 -1.2 -1.1 -1.1 -1.5 -0.8 -1.1 0.6 -0.6 -0.5 -1.3 -1.1 -0.8 0.8 1.5 -0.9 -0.9 -1.8 -1.5 1.5 1.5 0.4 1.8 1.6 1.6 1.6 2.1
Relative age of first facial hair 2.3 4.7 8.4 -2.3 -2.2 -2.1 -1.7 -2.3 -1.8 -2.4 2.3 -1.9 -1.0 -2.0 -2.2 -2.1 0.4 2.6 -2.6 -1.8 -1.5 -2.3 2.8 2.6 2.9 2.5 2.5 2.5 1.5 2.3
Other serious medical condition/disability diagnosed by doctor 1.0 1.3 7.4 0.9 1.0 1.2 0.1 0.2 1.1 1.0 -1.1 1.1 1.5 1.0 1.2 1.2 2.7 -0.4 1.1 1.1 0.3 0.5 -0.7 -0.7 -0.3 -0.1 -0.4 -0.5 2.6 -1.0
Ever used hormone-replacement therapy (HRT) 0.3 0.4 1.6 0.6 0.5 0.5 -1.1 0.8 0.6 0.6 -0.3 -0.2 0.9 0.3 0.5 1.0 -1.2 -0.6 0.6 -0.0 0.8 0.6 -0.4 -0.6 -0.2 -0.5 -0.3 -0.3 0.1 -0.5
Ever had hysterectomy (womb removed) 0.1 0.2 0.6 0.3 0.5 0.2 0.6 0.5 0.5 0.4 -0.4 0.1 0.4 0.3 0.2 0.4 0.8 -0.5 0.5 0.3 -0.2 0.2 -0.3 -0.4 -0.8 -0.3 -0.3 -0.2 -0.5 0.0
Systolic blood pressure, automated reading 0.1 0.2 1.1 0.4 -0.2 0.3 -0.9 0.4 -0.2 -0.2 -0.1 -0.9 0.2 -0.3 0.4 0.6 -0.1 -0.1 0.2 0.2 0.6 0.1 -0.1 -0.3 0.0 0.0 0.0 0.0 1.1 -0.3
Eye problems/disorders: Diabetes related eye disease 2.8 3.1 5.2 -1.8 -1.8 -1.8 -1.9 -1.8 -2.2 -2.0 2.2 -2.3 -2.1 -2.1 -1.9 -1.9 -0.7 1.7 -1.6 -0.9 -1.8 -1.3 1.9 1.8 1.4 1.3 1.6 1.7 -1.1 2.1
Angina 2.8 3.7 7.7 2.0 2.3 2.0 1.6 1.5 2.8 2.4 -1.8 1.8 2.7 2.0 2.0 2.2 1.4 -1.8 2.1 1.9 1.5 1.9 -1.8 -1.9 -2.1 -1.7 -1.8 -1.8 -0.2 -1.4
Medication for hormone replacement therapy 0.2 0.2 1.4 -0.0 -0.3 -0.2 -0.5 0.5 -0.4 0.1 0.3 -1.2 -0.3 -0.4 -0.2 -0.2 -0.5 -0.2 0.2 -0.8 0.1 0.3 -0.0 -0.2 0.1 -0.3 0.1 0.1 -0.8 -0.0
Vitamin and mineral supplements 0.1 0.1 1.2 0.1 0.3 -0.0 -0.4 -0.4 0.2 0.1 -1.1 0.2 0.5 0.1 -0.0 -0.1 -0.5 -0.1 0.2 -0.8 -0.0 -0.2 0.0 0.1 -0.0 0.0 -0.2 -0.2 -0.0 -0.0
Supplements: Zinc 0.2 0.2 1.1 0.3 -0.1 0.4 0.0 0.3 -0.0 0.1 0.2 0.0 -0.3 0.1 0.4 0.5 1.1 -0.2 -0.0 1.1 0.2 0.3 -0.5 -0.5 -1.0 -0.1 -0.1 -0.1 0.5 -0.1
Medication: Co-codamol 0.8 0.9 2.4 -0.9 -1.1 -0.9 -0.3 -0.6 -0.4 -0.6 1.5 -0.8 -0.5 -0.8 -0.9 -1.2 0.4 1.1 -1.0 -0.3 -0.5 -1.4 1.2 1.2 1.5 1.2 1.0 1.0 1.2 0.8
Medication: Metformin 5.5 7.7 10.5 -2.8 -3.1 -2.8 -2.8 -2.9 -3.2 -3.2 3.1 -2.1 -2.6 -3.2 -2.8 -3.1 -0.3 3.2 -2.9 -2.2 -2.5 -3.0 3.0 3.2 3.0 2.9 2.6 2.6 1.3 2.6
Diabetes (father) 7.6 9.4 12.5 -3.4 -3.3 -3.3 -2.8 -3.2 -3.4 -3.4 2.7 -3.5 -3.2 -3.3 -3.3 -3.3 -0.4 3.5 -3.1 -2.3 -3.3 -3.2 3.2 3.2 3.0 3.1 3.2 3.3 0.6 2.9
Diabetes (mother) 1.5 2.0 3.2 -1.4 -1.4 -1.1 -1.6 -1.5 -1.3 -1.7 1.5 -1.8 -0.8 -1.4 -1.3 -1.6 -1.4 1.6 -1.4 -1.2 -1.4 -1.3 1.5 1.7 1.8 1.4 1.2 1.1 0.5 1.2
Severe depression (siblings) 1.7 1.9 3.5 1.5 1.4 1.4 1.8 1.1 1.8 1.7 -1.2 0.8 1.6 1.6 1.5 1.9 1.1 -1.6 1.0 1.6 1.0 1.6 -1.3 -1.5 -1.3 -1.1 -1.0 -1.0 0.7 -1.2
Pack years adult smoking proportion 0.2 0.3 1.7 0.3 0.6 0.4 0.8 0.1 0.8 0.6 -0.2 1.2 0.7 0.6 0.4 0.6 1.3 -0.1 0.4 0.7 0.0 0.4 -0.2 -0.3 -0.6 -0.5 -0.4 -0.3 -0.8 0.3
Impedance of leg (right) 3.9 18.7 36.5 4.3 4.5 4.2 6.0 4.1 5.4 5.5 -4.3 5.2 4.4 5.2 4.3 3.9 2.4 -4.3 4.0 3.0 4.4 3.9 -4.3 -4.2 -3.1 -4.2 -4.5 -4.5 -1.1 -4.5
Leg fat-free mass (left) 0.3 1.4 12.2 -0.6 -0.9 -0.7 -3.5 -0.8 -2.0 -2.0 0.7 -2.2 -1.3 -1.4 -0.8 -0.4 -0.7 0.6 -0.6 0.4 -0.6 -0.2 0.6 0.4 -0.3 0.4 0.7 0.8 -0.6 1.1
Trunk fat percentage 0.3 1.1 7.2 -0.7 -0.9 -0.8 -2.0 -0.7 -1.4 -1.2 0.7 -2.7 -1.2 -1.3 -0.9 -0.3 0.5 0.8 -0.6 0.5 -0.6 -0.2 0.8 0.4 0.1 0.5 1.0 1.1 -0.6 1.1
Hand grip strength (right) 4.1 11.1 17.8 3.7 3.4 3.6 1.9 3.8 3.1 3.2 -3.2 1.9 3.1 3.5 3.6 3.7 1.2 -3.8 3.5 3.4 3.8 3.3 -3.8 -3.7 -4.2 -3.6 -3.8 -3.8 -1.4 -2.9
Townsend deprivation index at recruitment 0.8 1.2 4.7 -1.0 -1.0 -1.0 -1.2 -1.3 -0.8 -0.7 0.6 -0.3 -1.1 -0.9 -1.0 -0.5 1.5 1.3 -0.9 -0.7 -1.3 -1.1 1.1 0.9 -0.7 1.2 1.4 1.4 0.5 2.2
Current tobacco smoking 2.0 3.2 7.0 -2.0 -1.7 -2.1 -1.2 -2.2 -1.1 -1.5 1.7 -1.1 -1.4 -1.6 -2.1 -1.8 -0.7 2.2 -2.0 -1.9 -2.7 -2.0 2.0 1.9 1.7 1.9 2.0 2.0 0.6 1.9
Average weekly fortified wine intake 0.2 0.2 2.8 0.1 0.1 0.3 0.1 0.2 0.5 0.3 0.0 0.6 0.6 0.1 0.4 0.5 1.2 -0.0 -0.1 0.6 0.2 -0.0 -0.1 -0.0 0.2 0.3 0.1 0.0 1.7 -0.4
Maternal smoking around birth 0.6 0.9 1.7 -1.2 -1.0 -1.1 -0.1 -0.7 -0.2 -0.5 1.2 -0.8 -0.3 -0.8 -1.2 -0.8 0.5 1.0 -1.1 -0.9 -1.1 -0.7 1.3 1.3 1.2 0.9 1.0 1.0 -0.7 1.3
Fed-up feelings 0.1 0.2 1.1 -0.4 -0.4 -0.5 -0.5 -0.5 -0.0 -0.1 0.3 -0.5 -0.1 -0.3 -0.4 0.0 0.9 0.4 -0.6 0.1 -1.1 -0.3 0.4 0.2 0.2 0.5 0.6 0.7 0.5 0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 2.2 3.0 5.3 -1.7 -1.7 -1.7 -1.9 -2.2 -1.4 -1.4 1.8 -1.7 -1.1 -1.7 -1.6 -1.6 0.4 1.9 -1.6 -1.4 -2.3 -1.6 2.1 1.9 1.6 1.8 1.9 1.9 0.8 2.2
Relative age voice broke 0.9 1.4 4.8 -1.0 -1.0 -1.0 -2.2 -1.4 -1.3 -1.7 1.0 -1.2 -0.8 -1.2 -1.0 -0.9 -1.5 1.0 -1.0 -0.8 -1.4 -0.6 1.3 1.1 1.8 0.8 1.0 1.1 -0.2 0.8
Taking other prescription medications 0.3 0.5 2.5 0.7 0.5 0.7 0.7 0.3 0.5 0.8 -1.3 0.3 0.4 0.2 0.6 0.9 1.6 -0.5 0.8 1.0 0.1 1.0 -0.5 -0.8 0.0 -0.7 -0.4 -0.3 -0.1 -0.8
Age when periods started (menarche) 0.2 0.5 6.5 0.1 -0.2 0.1 -1.6 0.0 -0.5 -0.4 0.5 -0.1 0.0 -0.4 0.0 0.0 -2.5 0.4 0.0 -0.6 0.5 0.1 0.5 0.3 1.1 -0.2 -0.1 -0.1 -0.7 0.2
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 2.0 0.9 0.9 0.7 0.7 1.4 0.7 0.7 -0.3 0.4 0.9 0.7 0.7 0.5 0.1 -0.6 0.9 1.1 0.7 1.0 -0.8 -0.8 -0.2 -1.1 -1.0 -1.0 -0.9 -1.0
Heel bone mineral density (BMD) T-score, automated (left) 0.9 2.0 4.1 -1.4 -1.2 -1.3 -1.5 -1.1 -1.6 -1.6 1.7 -1.9 -1.5 -1.4 -1.4 -1.7 -2.0 1.3 -1.3 -0.8 -1.5 -0.9 1.3 1.4 1.3 0.9 1.0 1.0 -1.5 1.4
Tinnitus: Yes, but not now, but have in the past 2.3 2.4 4.5 1.8 1.7 1.6 1.2 1.6 2.1 2.0 -1.3 1.2 1.8 1.7 1.7 2.0 0.6 -1.6 1.3 1.7 1.1 1.6 -1.6 -1.8 -1.9 -1.5 -1.4 -1.4 -0.0 -1.2
Qualifications: CSEs or equivalent 7.1 9.4 11.9 3.4 3.2 3.3 2.5 3.3 3.1 3.1 -2.7 2.4 3.0 3.4 3.4 3.4 1.8 -3.3 2.9 3.3 3.5 3.4 -3.3 -3.4 -2.6 -3.2 -3.2 -3.2 -0.8 -3.2
Serious illness, injury or assault to yourself 0.6 0.7 2.0 -0.9 -0.8 -0.6 -0.4 -1.2 -0.7 -0.9 0.2 -0.9 -0.5 -0.7 -0.7 -0.4 0.1 1.0 -0.8 -1.0 -0.6 -0.7 1.0 0.9 0.2 1.2 1.2 1.2 1.1 1.4
High blood pressure 0.1 0.3 1.1 0.8 0.2 0.4 -0.8 0.6 0.2 0.5 -0.4 -0.5 0.3 0.1 0.7 0.6 0.2 -0.8 0.3 0.8 0.2 0.8 -0.6 -0.8 -0.1 -0.6 -0.5 -0.5 0.3 -1.1
Hayfever, allergic rhinitis or eczema 0.6 1.3 4.6 1.0 0.9 0.9 0.4 0.8 0.5 0.9 -1.4 -0.1 -0.1 0.5 0.9 1.6 -0.4 -1.1 1.1 1.8 0.9 2.0 -0.9 -1.3 -0.0 -1.7 -0.9 -0.8 -2.1 -1.1
Multivitamins +/- minerals 1.4 1.7 5.2 -1.5 -1.6 -1.4 -0.0 -1.0 -0.8 -1.0 2.3 -1.1 -1.3 -1.2 -1.4 -1.3 -0.1 1.5 -1.7 -0.9 -1.4 -1.4 1.2 1.3 0.6 1.6 1.6 1.6 1.1 1.4
Stomach or abdominal pain in last month 0.3 0.4 4.2 0.4 0.4 0.4 0.8 0.1 0.4 0.7 -0.8 0.9 0.3 0.4 0.4 0.9 2.1 -0.3 0.4 0.7 -0.5 0.5 -0.2 -0.4 -0.3 -0.3 -0.1 -0.1 0.1 -0.1
Supplements: Glucosamine 2.2 2.9 6.2 -1.7 -1.7 -1.5 -0.6 -1.7 -1.6 -2.1 2.0 -1.0 -0.9 -1.7 -1.4 -1.2 -1.2 1.9 -1.9 -1.6 -1.3 -2.0 1.9 1.9 2.5 2.1 1.9 1.9 2.4 1.2
Diverticular disease/diverticulitis (self-reported) 3.9 4.7 6.9 2.3 2.3 2.2 1.9 2.4 1.9 2.4 -2.3 1.9 1.3 2.4 2.2 1.8 0.6 -2.5 2.6 1.8 1.8 2.4 -2.4 -2.3 -1.8 -2.5 -2.5 -2.5 -1.6 -2.3
Medication: Atenolol 0.1 0.1 0.8 -0.1 0.1 -0.2 -0.5 -0.3 0.4 0.3 -0.1 0.2 0.1 -0.0 -0.2 -0.2 -0.7 0.0 -0.1 -0.9 0.0 -0.2 0.2 0.2 0.0 0.3 0.2 0.2 0.2 0.2
Medication: Levothyroxine sodium 4.5 7.6 14.8 3.0 3.0 3.0 2.3 2.8 2.8 3.1 -3.5 1.8 2.4 2.8 3.0 3.9 2.1 -2.9 3.4 2.8 1.6 3.1 -2.8 -3.3 -2.3 -2.9 -2.3 -2.2 -0.4 -2.8
Sitting height 0.2 1.4 4.1 1.3 1.4 1.1 -1.1 1.3 0.7 0.6 -0.9 0.3 0.9 1.2 1.1 1.3 -0.7 -1.4 1.3 1.1 1.1 1.4 -1.4 -1.4 -2.0 -1.3 -1.3 -1.4 -1.1 -0.9
Chronic bronchitis/emphysema (father) 1.1 1.3 2.6 1.1 1.0 1.1 0.9 1.5 1.4 1.5 -0.8 0.4 0.9 1.1 1.2 0.9 0.2 -1.3 0.7 1.1 1.0 1.6 -1.2 -1.2 -1.0 -1.5 -1.3 -1.2 -1.5 -1.1
High blood pressure (mother) 0.4 0.6 1.6 0.9 1.0 0.8 -0.5 0.9 0.9 0.9 -0.6 0.1 1.1 1.1 0.8 0.6 1.3 -0.7 0.7 0.6 0.7 0.9 -0.7 -0.7 -0.4 -0.6 -0.8 -0.8 0.6 -0.9
Body mass index (BMI) 1.9 7.9 23.6 -2.6 -3.0 -2.6 -4.1 -2.4 -3.9 -3.9 2.8 -4.9 -3.1 -3.6 -2.7 -2.0 -0.6 2.7 -2.5 -0.8 -2.6 -1.9 2.7 2.3 2.1 2.2 2.9 3.0 -0.2 2.8
Impedance of leg (left) 3.3 16.1 31.8 4.0 4.3 3.8 5.6 3.8 5.3 5.4 -4.1 4.7 4.1 4.9 4.0 3.7 2.0 -4.1 3.6 2.5 3.7 3.5 -4.1 -3.9 -3.3 -3.8 -4.0 -4.1 -0.8 -4.1
Leg predicted mass (left) 0.3 1.6 12.9 -0.7 -1.0 -0.8 -3.6 -0.8 -2.1 -2.1 0.8 -2.3 -1.4 -1.5 -0.9 -0.5 -0.8 0.7 -0.6 0.3 -0.7 -0.3 0.7 0.5 -0.2 0.5 0.8 0.9 -0.7 1.1
Trunk fat mass 0.2 1.1 7.5 -0.6 -0.8 -0.6 -2.5 -0.6 -1.5 -1.4 0.6 -2.7 -1.1 -1.2 -0.7 -0.0 0.3 0.7 -0.5 0.7 -0.6 -0.0 0.6 0.3 -0.1 0.4 0.9 1.0 -0.6 1.0
Waist circumference 0.2 0.7 3.2 0.7 0.4 0.6 -1.3 0.6 -0.4 -0.4 -0.7 -1.3 0.1 -0.2 0.6 1.2 1.2 -0.4 0.9 1.8 0.3 1.4 -0.5 -0.9 -0.9 -1.0 -0.4 -0.3 -1.3 -0.1
Number of incorrect matches in round 0.2 0.4 1.4 -0.7 -0.5 -0.7 -0.2 -0.7 -0.7 -0.8 0.2 -0.0 -0.7 -0.5 -0.7 -0.2 0.8 0.6 -0.6 0.8 -1.2 -0.2 0.6 0.4 1.0 0.3 0.7 0.8 -0.5 0.2
Past tobacco smoking 0.3 0.5 3.7 -0.4 -1.0 -0.5 -0.4 0.2 -1.2 -0.7 0.9 -0.1 -1.2 -0.7 -0.4 -0.8 -1.9 0.4 -1.0 -0.6 -0.4 -0.6 0.1 0.3 0.3 0.3 0.2 0.2 -0.1 -0.1
Alcohol usually taken with meals 3.1 5.1 8.1 2.3 2.8 2.4 1.8 2.1 2.2 2.2 -2.4 2.9 2.1 2.5 2.3 1.8 1.0 -2.1 2.6 2.1 2.3 2.2 -2.5 -2.3 -1.5 -2.4 -2.5 -2.6 -0.9 -2.8
Nervous feelings 2.4 4.5 9.4 2.2 2.2 2.5 1.3 1.9 2.9 2.6 -1.5 2.6 2.9 2.3 2.4 2.9 3.1 -1.7 2.1 2.1 1.3 2.0 -1.7 -1.9 -1.0 -1.5 -1.8 -1.8 1.4 -2.0
Frequency of tenseness / restlessness in last 2 weeks 4.2 6.6 16.2 2.5 2.8 2.8 1.5 2.4 2.9 2.7 -2.4 2.0 3.2 2.8 2.8 3.2 4.0 -2.4 2.4 3.3 2.4 2.6 -2.3 -2.5 -1.4 -2.1 -2.0 -2.0 1.1 -2.7
Hearing difficulty/problems with background noise 0.5 0.7 5.5 -0.6 -0.4 -0.3 -0.1 -0.9 0.4 0.2 -0.3 -0.1 -0.0 -0.4 -0.4 -0.1 2.3 0.8 -0.2 0.1 -1.1 -1.0 0.5 0.5 -0.6 1.2 1.0 0.9 2.0 1.1
Hair/balding pattern: Pattern 2 0.2 0.3 1.1 0.6 0.5 0.4 0.8 0.1 0.3 0.4 -0.9 0.0 0.2 0.5 0.4 0.6 0.8 -0.2 0.5 1.1 0.6 0.6 -0.5 -0.6 -0.7 -0.4 -0.4 -0.4 0.1 -0.4
Had menopause 0.0 0.0 0.2 -0.2 0.0 -0.3 0.1 0.2 0.2 0.1 -0.2 -0.1 -0.0 -0.1 -0.4 0.1 -0.4 0.1 0.2 -0.2 0.1 -0.2 -0.1 -0.1 -0.3 0.0 0.2 0.2 -0.3 -0.1
Had other major operations 1.1 1.3 4.4 1.2 1.0 1.2 -0.4 0.8 0.8 1.1 -1.5 0.8 0.5 1.0 1.2 1.3 1.4 -1.1 0.8 2.1 1.2 1.1 -1.4 -1.5 -1.5 -1.0 -0.9 -0.9 0.5 -1.3
Forced vital capacity (FVC) 0.5 1.9 4.5 1.2 1.3 1.2 0.8 1.2 1.4 1.5 -0.8 2.1 1.2 1.5 1.1 0.3 -1.5 -1.5 1.1 0.4 1.7 1.1 -1.5 -1.1 -1.5 -1.6 -1.9 -2.0 -2.0 -1.2
Heel bone mineral density (BMD) T-score, automated (right) 0.7 1.7 3.9 -1.3 -1.2 -1.1 -1.3 -1.2 -1.4 -1.4 1.4 -1.5 -1.4 -1.2 -1.2 -1.6 -2.0 1.1 -1.3 -1.2 -1.8 -0.9 1.2 1.4 1.6 0.8 0.8 0.8 -1.1 1.0
Ever unenthusiastic/disinterested for a whole week 0.2 0.3 1.0 -0.5 -0.2 -0.7 1.0 -0.3 0.3 0.2 0.8 -0.2 -0.1 0.1 -0.6 -0.9 0.1 0.6 -1.0 -0.1 -0.3 -0.3 0.5 0.5 0.5 0.5 0.5 0.5 0.1 0.4
Qualifications: None of the above 1.7 3.7 8.7 1.7 2.0 1.9 2.5 1.4 2.1 2.0 -2.4 1.9 2.1 1.6 1.9 2.4 2.9 -1.7 1.9 2.7 1.6 2.1 -1.6 -1.8 -1.7 -1.8 -1.5 -1.4 -0.9 -1.0
Financial difficulties in last 2 years 0.1 0.1 0.3 -0.2 -0.0 -0.0 0.4 -0.2 0.1 -0.1 0.4 -0.5 -0.2 -0.2 -0.2 0.1 -0.3 0.2 0.0 -0.4 0.2 -0.0 0.3 0.2 0.5 0.1 0.3 0.3 -0.0 0.2
Mouth/teeth dental problems 0.5 0.8 3.6 -0.7 -0.6 -0.5 0.3 -0.2 -0.5 -0.9 1.9 -0.2 0.1 -0.3 -0.3 -0.8 -1.1 0.8 -1.2 -1.4 -0.4 -1.0 0.8 0.9 0.9 1.0 0.7 0.6 1.6 0.6
Heart attack 0.1 0.1 0.6 0.2 0.0 0.4 0.1 -0.2 0.4 0.3 0.1 0.1 0.2 0.0 0.3 0.4 -0.5 -0.0 0.3 -0.7 -0.1 -0.1 -0.1 -0.2 -0.4 0.1 -0.0 -0.0 0.8 0.1
Allergy 0.3 0.7 4.4 -0.6 -0.7 -0.5 -0.4 -0.6 -0.5 -0.7 1.3 -0.2 0.1 -0.3 -0.5 -1.2 0.5 0.8 -1.1 -1.0 -0.8 -1.6 0.5 0.8 0.1 1.2 0.5 0.3 2.1 0.5
Pain all over the body in last month 0.5 0.5 2.1 -0.7 -0.5 -0.3 0.6 -0.7 -0.0 -0.3 0.8 -0.7 0.3 -0.5 -0.3 -0.5 0.4 0.8 -0.4 -1.2 -0.3 -0.6 0.9 0.9 1.2 0.9 0.8 0.7 1.5 0.6
Diabetes (self-reported) 5.6 8.6 11.8 -3.0 -3.2 -2.8 -3.2 -3.2 -3.4 -3.4 3.3 -3.1 -2.5 -3.2 -2.8 -2.9 -0.4 3.2 -2.9 -2.3 -2.7 -3.1 3.2 3.3 3.4 3.1 2.8 2.8 1.5 2.6
Hayfever/allergic rhinitis (self-reported) 0.5 0.7 1.6 0.7 0.7 0.6 1.3 1.0 0.7 0.8 -0.9 0.7 0.5 0.4 0.6 0.7 -0.5 -1.1 0.9 0.3 1.1 1.2 -0.7 -0.8 -0.3 -1.0 -0.8 -0.7 -1.2 -0.9
Medication: Ramipril 1.0 1.3 2.5 -1.2 -1.0 -1.3 -1.5 -1.4 -0.6 -0.6 1.0 -1.6 -0.9 -1.3 -1.2 -1.2 0.5 1.3 -1.2 -0.8 -1.5 -0.8 1.1 0.9 1.1 0.9 1.3 1.4 -0.3 0.9
Medication: Simvastatin 1.1 1.7 3.3 1.4 1.3 1.6 0.2 1.4 1.5 1.5 -1.2 0.5 1.5 1.1 1.5 1.8 1.1 -1.3 1.4 1.3 1.1 1.6 -1.2 -1.4 -0.8 -1.4 -1.3 -1.3 -0.6 -1.2
Fluid intelligence score 5.2 10.8 17.5 -3.5 -3.3 -3.6 -2.6 -3.6 -3.1 -3.5 3.6 -2.7 -2.6 -3.3 -3.5 -4.2 -1.6 4.1 -3.5 -3.3 -2.7 -3.8 3.5 3.7 3.4 3.5 3.3 3.3 1.3 3.1
Illnesses of siblings 0.3 0.4 2.6 0.3 0.3 0.3 0.7 0.7 -0.0 -0.2 1.1 0.4 0.3 0.3 0.3 -0.1 -1.1 -0.1 0.2 0.2 1.6 0.2 -0.2 0.1 -0.1 -0.5 -0.8 -0.8 -1.2 0.1
Neuroticism score 3.0 6.3 10.5 2.7 2.9 2.7 1.7 2.6 3.0 2.8 -2.4 2.3 2.8 2.9 2.7 3.2 2.1 -2.4 2.8 2.9 1.5 2.7 -2.5 -2.7 -1.9 -2.4 -2.3 -2.3 -0.1 -2.6
Weight 0.3 1.3 9.5 -0.6 -0.8 -0.6 -3.1 -0.6 -1.8 -1.8 0.6 -2.9 -1.2 -1.4 -0.7 0.0 -0.1 0.6 -0.5 0.7 -0.7 0.0 0.5 0.2 -0.1 0.3 0.8 0.9 -0.7 0.9
Impedance of arm (right) 1.0 4.7 11.5 2.0 2.4 1.9 3.1 2.0 3.1 3.4 -2.2 3.1 2.1 2.8 1.9 1.3 1.0 -1.9 1.9 1.0 2.1 1.4 -2.2 -1.9 -2.1 -1.7 -2.1 -2.2 0.0 -1.9
Arm fat percentage (right) 1.4 5.4 19.0 -2.1 -2.4 -2.1 -3.3 -2.0 -3.1 -3.0 2.2 -4.4 -2.6 -3.0 -2.2 -1.6 -0.0 2.4 -2.0 -0.6 -1.9 -1.5 2.3 1.8 1.5 1.9 2.5 2.6 -0.1 2.5
Trunk fat-free mass 0.1 0.8 3.9 0.9 0.6 0.9 -2.0 0.6 -0.4 -0.5 -0.9 -0.8 0.2 0.2 0.8 1.2 0.1 -1.0 0.9 1.4 0.6 1.2 -1.0 -1.1 -1.3 -1.0 -0.8 -0.7 -0.7 -0.7
Hip circumference 1.7 7.5 24.2 -2.5 -2.8 -2.7 -4.7 -2.1 -3.8 -3.7 2.4 -4.9 -3.3 -3.4 -2.7 -2.1 -1.8 2.5 -2.2 -1.0 -2.5 -1.8 2.4 2.1 1.7 2.0 2.6 2.7 -0.8 2.5
Time employed in main current job 1.3 1.5 4.0 1.3 1.1 1.1 1.4 1.1 1.3 1.6 -1.5 1.5 1.0 1.4 1.1 1.4 1.0 -1.4 1.1 0.5 1.4 0.9 -1.3 -1.4 -2.0 -1.0 -1.0 -1.0 0.0 -0.8
Alcohol intake versus 10 years previously 1.8 2.7 5.2 -1.8 -1.8 -1.8 -0.9 -1.9 -1.5 -1.6 1.4 -1.1 -1.3 -1.8 -1.8 -1.3 1.5 1.9 -1.7 -0.8 -2.2 -1.8 1.9 1.7 0.8 2.0 2.0 2.0 1.2 2.3
Father’s age at death 0.1 0.1 0.8 0.1 0.2 0.6 0.1 -0.4 0.3 0.2 0.4 0.4 0.9 0.0 0.4 -0.1 0.3 -0.1 0.1 -0.5 0.8 -0.2 0.2 0.2 0.5 0.2 -0.1 -0.1 0.8 0.1
Worrier / anxious feelings 8.6 16.2 27.6 4.4 4.5 4.6 2.7 3.9 4.0 4.1 -3.8 3.8 4.1 4.4 4.6 5.3 3.3 -4.3 4.2 4.4 3.2 4.4 -4.2 -4.3 -3.0 -3.9 -4.0 -4.0 0.5 -4.5
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 2.2 -0.9 -0.6 -0.9 -1.3 -1.3 -0.6 -0.4 0.3 -1.1 -0.9 -0.8 -0.8 -0.3 0.7 1.0 -0.6 -0.1 -1.5 -0.4 0.8 0.5 0.7 0.8 1.3 1.4 0.6 0.7
Falls in the last year 0.2 0.2 1.4 0.1 0.3 0.2 -0.5 0.0 0.6 0.0 -0.4 1.2 0.9 0.1 0.2 0.1 0.7 0.3 0.1 0.8 0.1 -0.2 -0.3 -0.1 -0.3 0.2 -0.0 -0.1 1.1 -0.3
Hair/balding pattern: Pattern 3 0.3 0.4 2.9 0.2 0.2 0.8 1.5 0.5 1.0 0.7 0.4 0.5 1.0 0.3 0.6 0.4 1.3 -0.2 0.1 0.1 0.1 -0.3 0.0 0.2 0.1 0.4 -0.1 -0.1 1.7 0.0
Number of live births 1.4 2.0 4.4 -1.5 -1.5 -1.8 -1.8 -1.3 -1.7 -1.6 1.0 -2.1 -1.8 -1.8 -1.7 -1.4 -1.4 1.2 -1.1 -1.2 -0.7 -1.1 1.1 1.1 1.5 0.8 1.3 1.3 -1.1 0.7
Forced expiratory volume in 1-second (FEV1) 0.3 0.9 3.4 0.8 0.8 0.8 -0.3 0.7 0.5 0.7 -0.4 0.9 0.3 0.8 0.7 -0.0 -1.8 -1.0 0.6 0.4 0.9 0.7 -1.1 -0.8 -0.9 -1.2 -1.4 -1.4 -1.7 -1.0
Pulse rate 0.8 1.3 2.9 -1.2 -1.3 -1.1 -0.6 -1.4 -0.9 -1.1 1.1 -1.3 -0.8 -1.1 -1.1 -0.7 -0.3 1.4 -1.2 -1.0 -1.2 -1.4 1.4 1.2 0.9 1.2 1.4 1.4 0.4 1.7
Happiness 0.3 0.4 1.0 -0.6 -0.7 -0.7 -0.2 -0.4 -0.2 -0.0 0.9 -0.6 -0.6 -0.5 -0.6 -0.7 0.6 0.9 -1.0 -0.1 -0.4 -0.6 0.7 0.6 0.6 0.7 0.6 0.6 0.4 0.6
Noisy workplace 0.8 0.9 2.7 1.1 1.0 1.2 -0.3 0.9 0.7 0.8 -0.8 -0.1 0.6 0.9 1.3 1.6 0.6 -1.1 1.0 1.6 0.7 0.9 -1.1 -1.2 -1.6 -0.9 -0.8 -0.8 0.4 -0.5
Qualifications: A levels/AS levels or equivalent 0.1 0.3 2.2 -0.1 -0.4 -0.0 -0.3 -0.4 -0.2 -0.2 0.4 0.3 -0.1 -0.2 -0.0 -1.0 -1.1 0.1 -0.4 -1.5 0.2 -0.5 -0.0 0.3 0.4 0.3 -0.2 -0.3 0.7 -0.4
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.3 1.3 0.5 0.7 0.7 0.1 0.4 0.8 0.6 -0.4 0.7 0.8 0.6 0.6 0.7 0.6 -0.2 0.6 0.8 0.3 0.4 -0.4 -0.5 0.0 -0.2 -0.2 -0.2 1.2 -0.7
Mouth/teeth dental problems: Dentures 0.5 0.8 4.4 -0.8 -0.8 -0.9 -2.1 -1.2 -0.8 -0.7 -0.2 -0.9 -1.1 -1.1 -1.0 -0.6 0.3 0.6 -0.3 -0.1 -1.1 -0.9 0.8 0.7 0.4 0.7 0.9 0.9 -0.2 0.9
Asthma 0.2 0.4 2.9 -0.9 -0.4 -1.1 0.3 -0.2 -0.1 -0.1 0.2 -0.0 -0.5 -0.5 -1.2 -0.7 -0.5 0.5 -0.5 -0.6 -0.5 -0.2 0.6 0.5 0.5 0.2 0.8 0.9 -1.7 0.7
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 1.6 0.5 0.6 0.6 1.0 0.2 0.9 1.0 -0.8 0.9 0.7 0.6 0.5 0.6 -0.2 -0.7 0.7 0.1 0.6 0.9 -0.4 -0.4 0.0 -0.8 -0.8 -0.8 -1.2 -0.5
Medication: Cholesterol lowering 0.3 0.5 1.1 0.6 0.7 0.7 0.8 0.6 1.1 1.0 -0.3 0.6 1.1 0.7 0.7 0.7 0.5 -0.4 0.5 0.4 0.6 0.7 -0.5 -0.5 -0.6 -0.8 -0.8 -0.8 -1.0 -0.2
Depression (self-reported) 0.2 0.3 1.1 -0.6 -0.2 -0.5 -0.4 -0.7 -0.1 -0.2 -0.0 -0.6 -0.3 -0.3 -0.6 -0.4 0.6 0.6 -0.1 0.1 -0.9 -0.0 0.6 0.4 0.1 0.2 0.6 0.7 -1.1 0.9
Medication: Lansoprazole 0.9 1.0 2.5 1.0 1.1 1.2 0.8 0.7 1.3 1.1 -0.9 1.3 1.6 1.1 1.1 1.3 1.2 -0.7 0.9 0.9 0.7 0.8 -0.8 -0.9 -0.9 -0.7 -0.7 -0.7 0.4 -0.7
Prospective memory result 0.2 0.2 1.6 0.2 0.3 0.5 0.0 0.3 -0.0 -0.1 -0.4 -0.2 0.4 0.1 0.5 0.5 0.8 -0.5 0.3 1.3 -0.0 0.6 -0.3 -0.4 -0.1 -0.4 -0.1 -0.1 -0.4 -0.3
Lung cancer (father) 0.6 0.7 1.8 -0.9 -0.7 -0.9 -0.5 -1.3 -0.6 -0.7 0.6 -1.0 -0.5 -0.7 -0.8 -0.8 0.5 0.8 -1.2 -0.2 -0.7 -0.7 1.1 1.0 1.1 0.9 1.0 1.0 0.2 1.0
Illnesses of mother 0.1 0.1 0.8 0.1 0.0 0.1 0.7 0.4 -0.1 0.1 -0.2 0.8 -0.5 0.1 0.0 0.3 0.1 -0.2 -0.0 0.7 0.6 -0.1 -0.2 -0.3 -0.9 -0.1 -0.1 -0.1 -0.3 0.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.6 3.6 0.5 0.6 0.5 -0.6 0.4 0.2 0.4 -0.6 0.6 0.1 0.4 0.4 -0.2 -1.5 -0.8 0.5 0.5 0.6 0.6 -0.9 -0.6 -0.9 -1.0 -1.0 -1.0 -1.9 -0.8
Pulse wave Arterial Stiffness index 0.3 0.4 2.8 0.5 0.5 0.6 -0.9 0.2 0.2 0.4 -0.7 0.4 0.3 0.4 0.5 1.0 0.4 -0.1 1.0 0.1 -0.6 -0.1 -0.3 -0.5 -1.0 0.1 -0.1 -0.1 1.7 0.0
Impedance of arm (left) 0.8 3.9 10.1 1.9 2.2 1.8 2.7 1.8 2.8 3.2 -2.1 2.7 1.8 2.6 1.8 1.1 0.8 -1.8 1.9 0.8 2.0 1.3 -2.0 -1.8 -2.1 -1.7 -2.0 -2.1 -0.2 -1.7
Arm fat mass (right) 0.7 3.0 14.7 -1.4 -1.7 -1.4 -3.3 -1.3 -2.6 -2.5 1.5 -3.8 -2.0 -2.3 -1.4 -0.8 -0.0 1.5 -1.2 0.2 -1.4 -0.7 1.4 1.0 0.8 1.0 1.7 1.8 -0.6 1.7
Trunk predicted mass 0.2 0.9 3.7 1.0 0.7 0.9 -1.9 0.7 -0.4 -0.4 -0.9 -0.7 0.3 0.3 0.9 1.3 0.1 -1.1 1.0 1.5 0.7 1.3 -1.1 -1.1 -1.4 -1.1 -0.9 -0.8 -0.8 -0.7
Standing height 1.6 15.5 24.6 4.2 4.4 4.1 1.7 3.7 4.1 4.1 -4.5 3.7 3.7 4.4 4.1 4.1 1.0 -4.4 4.2 3.2 3.8 4.0 -4.6 -4.4 -5.0 -4.1 -4.2 -4.3 -1.4 -3.8
Length of working week for main job 0.1 0.1 1.6 -0.1 0.1 -0.4 0.3 -0.1 -0.0 -0.1 -0.2 -0.2 -0.3 -0.1 -0.4 -0.1 -1.3 0.2 -0.0 -0.8 -0.1 -0.3 -0.0 -0.1 0.3 0.1 0.2 0.2 0.1 -0.4
Exposure to tobacco smoke at home 0.4 0.4 4.2 -0.2 0.1 0.2 1.5 -0.2 0.7 0.2 0.3 0.0 0.8 0.2 0.1 0.0 2.0 0.2 -0.4 0.2 0.6 -0.2 0.4 0.4 -0.0 0.5 0.4 0.4 1.0 0.8
Breastfed as a baby 0.1 0.1 0.8 -0.1 0.1 -0.2 -0.6 0.0 -0.4 -0.3 -0.2 -0.6 -0.6 -0.1 -0.3 -0.3 -0.9 0.2 -0.1 -0.2 -0.4 -0.1 -0.1 -0.2 -0.4 -0.1 0.2 0.2 -0.7 0.1
Tense / ‘highly strung’ 2.6 4.3 11.2 2.1 2.2 2.1 0.7 2.2 1.7 1.9 -2.7 1.6 1.4 2.0 2.1 2.9 2.8 -1.9 2.3 3.3 1.5 2.4 -2.1 -2.3 -2.0 -2.0 -1.7 -1.7 -0.3 -1.9
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 1.8 0.5 0.4 0.8 0.1 0.2 1.0 0.6 -0.1 0.7 1.0 0.4 0.7 1.3 1.3 -0.3 0.5 0.9 -0.2 0.8 -0.1 -0.4 -0.5 -0.3 -0.1 -0.1 0.4 0.3
Hair/balding pattern: Pattern 4 5.0 12.2 17.9 3.6 3.7 3.3 2.7 3.4 3.4 3.6 -4.1 4.0 2.7 3.6 3.4 3.6 0.5 -3.8 3.9 3.0 3.2 3.8 -3.9 -3.8 -2.6 -4.1 -3.8 -3.7 -2.5 -4.2
Birth weight of first child 0.1 0.2 1.3 -0.4 -0.5 -0.5 -1.2 -0.2 -0.7 -0.6 0.5 -0.6 -0.7 -0.5 -0.5 -0.8 -0.6 0.3 -0.7 -0.0 -0.2 -0.5 -0.0 0.1 -0.3 0.3 0.3 0.3 0.1 -0.0
Peak expiratory flow (PEF) 0.8 1.8 2.7 1.4 1.5 1.3 0.9 1.3 1.6 1.6 -0.8 1.1 1.5 1.4 1.3 1.1 0.4 -1.5 1.2 1.5 1.3 1.6 -1.3 -1.3 -0.9 -1.6 -1.6 -1.5 -1.6 -1.2
Pulse wave reflection index 0.2 0.2 3.3 0.0 0.0 -0.0 -1.8 0.1 -0.6 -0.6 0.2 -0.4 -0.2 -0.2 -0.0 0.2 0.1 0.5 0.1 0.3 -0.3 -0.3 -0.0 -0.1 -0.2 0.2 0.2 0.2 0.9 -0.0
Ever highly irritable/argumentative for 2 days 0.4 0.5 4.0 -0.7 -0.1 -0.6 1.2 -0.5 0.7 0.4 0.4 0.2 0.5 -0.2 -0.7 -0.5 2.0 0.7 -0.6 0.4 0.3 -0.2 0.8 0.7 0.7 0.6 0.8 0.9 -0.1 0.8
Loud music exposure frequency 2.3 2.5 5.4 -1.7 -1.5 -1.5 0.0 -1.5 0.0 -0.4 1.8 -0.8 0.1 -1.2 -1.5 -1.4 1.2 1.8 -1.7 -1.9 -1.5 -2.0 1.9 1.7 1.1 2.2 2.1 2.0 2.3 1.9
Qualifications: O levels/GCSEs or equivalent 0.3 0.4 1.2 0.7 0.5 0.7 0.8 0.5 0.8 0.7 0.0 0.6 1.1 1.0 0.7 0.5 -0.6 -0.5 0.2 -0.7 0.6 0.4 -0.6 -0.5 -0.0 -0.5 -0.8 -0.9 0.5 -1.0
Mouth/teeth dental problems: Bleeding gums 0.1 0.1 0.5 -0.2 -0.2 -0.4 -0.3 -0.5 -0.2 -0.1 -0.6 -0.4 -0.7 -0.2 -0.5 -0.2 -0.3 0.1 0.3 0.0 -0.5 -0.1 0.2 0.1 -0.1 0.1 0.2 0.2 -0.6 0.3
Blood clot in the leg (DVT) 0.1 0.2 2.2 0.2 0.0 0.3 -0.8 -0.1 -0.4 -0.1 0.4 0.2 -0.4 -0.2 0.2 0.0 -1.5 -0.1 0.2 -0.6 0.5 0.1 -0.3 -0.1 -0.2 -0.3 -0.3 -0.3 -0.7 -0.2
Medication: Paracetamol 2.2 3.7 6.6 2.0 1.9 2.2 2.2 1.9 2.4 2.3 -1.6 2.6 2.3 2.1 2.1 2.2 1.9 -2.0 1.9 1.5 1.4 1.7 -1.8 -1.9 -1.4 -1.5 -1.7 -1.8 0.9 -1.9
Headache pain in last month 0.3 0.6 2.7 -0.6 -0.7 -0.5 -1.1 -1.2 -0.8 -0.6 0.6 0.3 -0.9 -0.6 -0.5 -0.2 0.6 0.3 -1.0 -0.2 -0.9 -0.5 0.6 0.5 -0.1 1.0 1.0 0.9 1.6 0.9
Medication for cholesterol, blood pressure or diabetes 0.0 0.0 0.1 0.1 0.1 -0.0 -0.1 0.1 -0.3 -0.4 -0.3 -0.0 -0.0 0.1 0.0 0.0 -0.2 -0.1 0.1 0.1 0.4 0.0 -0.1 -0.1 -0.2 -0.0 -0.1 -0.1 0.2 -0.2
Glaucoma (self-reported) 0.6 0.6 1.6 0.7 0.7 0.6 -0.0 1.1 0.2 0.6 -0.8 -0.6 0.1 0.6 0.6 0.9 0.2 -1.0 0.9 0.7 1.0 1.1 -1.0 -1.2 -0.5 -1.1 -0.6 -0.6 -1.0 -1.3
Gout (self-reported) 0.1 0.2 2.0 0.1 0.4 0.4 1.4 0.3 0.7 0.5 -0.0 -0.2 0.8 0.5 0.3 0.4 0.5 0.3 0.3 -0.0 0.3 -0.0 0.1 0.0 0.4 -0.1 -0.1 -0.0 0.3 -0.1
Hypothyroidism/myxoedema (self-reported) 6.1 11.9 21.5 3.8 3.6 3.9 2.9 3.8 3.2 3.8 -3.9 2.1 2.6 3.5 3.9 4.6 2.3 -4.0 4.1 3.6 2.4 4.1 -3.6 -4.0 -2.9 -3.8 -3.2 -3.1 -1.0 -3.4
Medication: Amlodipine 1.3 1.8 3.2 1.4 1.5 1.4 1.4 1.7 1.7 1.8 -1.0 0.8 1.4 1.1 1.4 1.5 1.2 -1.2 1.8 1.7 1.4 1.4 -1.3 -1.4 -1.5 -1.2 -1.1 -1.1 -0.1 -1.0
Medication: Ventolin 100micrograms inhaler 0.2 0.2 0.8 -0.6 -0.2 -0.7 -0.4 -0.3 -0.2 0.1 -0.2 -0.7 -0.7 -0.4 -0.8 -0.1 0.2 0.2 0.0 0.0 -0.6 -0.1 0.2 0.0 -0.2 0.2 0.7 0.8 -0.9 0.3
Birth weight 0.2 0.3 2.6 0.4 0.6 0.2 0.2 0.4 0.5 0.3 -0.5 0.3 0.5 0.5 0.2 0.3 -0.4 -0.2 0.4 0.6 -0.4 0.6 -0.7 -0.6 -1.1 -0.8 -0.6 -0.6 -1.6 -0.2
Chronic bronchitis/emphysema (mother) 4.3 5.0 10.7 -2.2 -2.2 -1.9 -2.0 -2.4 -1.6 -1.8 2.4 -1.6 -1.2 -2.1 -1.9 -1.5 -1.7 2.1 -2.3 -3.3 -3.1 -2.2 2.6 2.4 2.4 2.6 2.5 2.5 2.3 2.3
High blood pressure (siblings) 0.4 0.5 6.1 0.1 -0.1 0.2 -1.0 -0.4 0.2 0.3 -0.9 -0.2 0.1 -0.0 0.2 0.8 1.0 -0.2 -0.0 0.1 -1.6 -0.2 -0.1 -0.3 0.2 0.5 0.6 0.6 2.5 -0.7
Forced vital capacity (FVC), Best measure 0.4 1.3 3.1 0.9 1.0 0.9 0.0 0.8 1.0 1.1 -1.1 1.7 0.9 1.1 0.8 0.2 -1.0 -1.3 0.9 0.7 1.3 0.9 -1.4 -1.0 -1.6 -1.3 -1.5 -1.5 -1.7 -1.1
Body fat percentage 0.5 1.9 9.9 -1.2 -1.4 -1.2 -2.2 -1.1 -1.9 -1.8 1.2 -3.1 -1.6 -1.8 -1.3 -0.6 0.3 1.3 -1.1 0.3 -1.0 -0.6 1.2 0.8 0.7 0.8 1.5 1.6 -0.6 1.5
Leg fat percentage (right) 0.3 1.1 6.2 -0.8 -1.1 -0.7 -1.2 -0.7 -1.4 -1.6 1.0 -2.5 -0.9 -1.3 -0.7 -0.1 0.8 1.0 -0.9 0.7 -0.5 -0.2 1.0 0.5 1.2 0.5 1.1 1.2 -0.2 0.8
Arm fat-free mass (right) 0.1 0.6 5.2 0.5 0.2 0.4 -2.3 0.3 -0.8 -0.9 -0.4 -1.3 -0.2 -0.2 0.4 0.9 -0.2 -0.6 0.4 1.1 0.3 1.0 -0.5 -0.7 -1.0 -0.7 -0.3 -0.3 -1.0 -0.1
Exposure to tobacco smoke outside home 0.3 0.4 2.7 0.1 0.4 -0.0 0.5 0.4 0.6 0.7 -1.1 -0.8 0.1 0.4 0.0 0.9 1.7 -0.3 0.2 0.8 0.1 0.2 -0.4 -0.7 -1.6 -0.2 0.4 0.5 -0.1 0.3
Comparative body size at age 10 0.8 2.3 4.1 -1.6 -1.5 -1.5 -0.4 -1.7 -1.2 -1.6 1.7 -1.5 -1.3 -1.4 -1.6 -1.8 -0.2 1.8 -1.8 -0.8 -1.8 -2.0 1.3 1.6 0.8 1.9 1.6 1.5 1.8 1.1
Number of full brothers 0.6 0.8 2.3 -0.8 -0.7 -1.1 -1.1 -1.0 -1.1 -0.8 -0.1 -0.0 -1.5 -0.6 -1.1 -1.0 -0.4 0.7 -0.4 -0.4 -1.0 -0.6 0.6 0.6 -0.7 0.4 0.7 0.7 -1.5 1.4
Worry too long after embarrassment 0.1 0.2 0.9 -0.4 -0.1 -0.2 -0.9 -0.3 -0.4 -0.3 0.8 -0.4 -0.5 -0.1 -0.2 -0.3 -0.6 0.6 -0.1 -0.4 -0.9 -0.4 0.2 0.3 0.2 0.4 0.4 0.4 0.5 0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.3 1.3 -0.4 -0.4 -0.3 -0.2 -0.6 0.2 -0.3 1.1 -0.0 0.3 -0.3 -0.3 -0.3 -0.5 0.6 -0.4 -0.6 -0.7 -0.2 0.9 0.7 0.7 0.6 0.6 0.6 0.5 1.0
Wheeze or whistling in the chest in last year 0.1 0.2 1.7 -0.1 0.1 -0.0 0.2 0.1 0.3 0.5 -0.3 0.1 -0.3 0.2 -0.1 0.6 1.0 -0.1 -0.1 0.5 0.2 0.4 -0.1 -0.3 -1.3 -0.1 0.4 0.5 -0.4 0.6
Number of children fathered 0.7 0.7 2.6 -0.6 -0.8 -0.4 -0.8 -0.3 -0.6 -1.1 1.4 -1.1 0.0 -0.7 -0.4 -0.6 -0.7 0.6 -0.6 -0.9 -1.0 -0.9 1.0 1.1 1.6 1.0 0.6 0.5 1.5 0.5
Reason for reducing amount of alcohol drunk: Health precaution 1.0 1.1 4.5 -0.8 -1.3 -0.8 -2.1 -0.5 -1.7 -1.4 0.8 -1.4 -1.3 -1.2 -0.7 -0.9 -1.3 0.9 -0.8 -1.1 -0.6 -0.9 1.0 1.0 0.5 0.9 0.8 0.8 0.3 1.2
Age at first live birth 0.1 0.1 0.7 0.1 0.1 0.3 -0.4 0.1 0.2 0.1 0.4 0.7 0.4 0.2 0.3 -0.3 -0.5 -0.1 -0.1 0.2 0.9 0.2 -0.0 0.0 0.8 -0.1 -0.3 -0.3 0.2 -0.5
Pulse wave peak to peak time 0.2 0.3 3.0 -0.1 -0.1 -0.3 1.0 0.2 0.2 -0.0 0.4 -0.0 0.2 0.0 -0.2 -0.6 -0.2 -0.3 -0.8 0.0 0.9 0.5 0.0 0.2 0.7 -0.4 -0.3 -0.3 -1.7 -0.2
Health satisfaction 0.2 0.3 3.8 -0.3 -0.4 -0.3 -0.2 -0.3 0.0 0.3 0.2 -0.4 -0.4 -0.3 -0.3 -0.1 1.9 0.4 -0.6 0.3 0.1 -0.5 0.3 0.3 -0.6 0.6 0.5 0.4 0.6 0.7
Shortness of breath walking on level ground 2.1 2.5 4.6 -1.9 -1.8 -1.8 -1.3 -2.1 -1.0 -1.0 1.0 -1.0 -1.3 -1.8 -1.8 -1.4 0.6 2.0 -1.4 -1.0 -1.7 -1.7 1.9 1.8 1.2 1.8 1.9 1.9 0.5 2.1
Qualifications: College or University degree 3.4 10.7 16.8 -3.4 -3.4 -3.4 -4.0 -3.0 -3.4 -3.6 3.4 -2.2 -3.0 -3.3 -3.4 -4.1 -2.9 3.5 -3.3 -3.7 -2.5 -3.8 3.2 3.5 2.5 3.6 3.1 3.0 1.7 3.0
Eye problems/disorders: None of the above 0.2 0.2 1.0 -0.3 -0.0 -0.2 -0.3 -0.2 0.3 -0.3 0.5 0.7 1.0 0.4 -0.2 -0.7 -0.1 0.5 -0.9 -0.4 -0.3 -0.6 0.4 0.6 0.3 0.6 0.1 0.1 0.9 0.3
Mouth/teeth dental problems: Loose teeth 4.2 5.0 8.4 -2.5 -2.4 -2.7 -1.9 -2.2 -2.2 -2.2 2.0 -1.4 -2.5 -2.6 -2.8 -2.4 -1.3 2.6 -2.2 -1.5 -2.3 -2.3 2.4 2.4 1.2 2.2 2.3 2.3 -0.7 2.9
Emphysema/chronic bronchitis 0.8 0.9 3.1 0.8 0.9 0.7 0.9 0.8 1.5 1.4 -0.9 1.3 1.0 1.0 0.8 1.1 1.8 -0.6 0.7 0.6 0.7 0.5 -0.7 -0.9 -1.5 -0.2 -0.3 -0.3 1.4 -0.3
Medication for pain relief, constipation, heartburn 2.4 4.1 8.1 -2.0 -2.0 -2.1 -2.5 -1.5 -2.6 -2.5 2.3 -2.1 -2.4 -2.0 -2.0 -2.5 -2.8 1.9 -2.1 -2.3 -1.3 -2.1 1.8 1.9 1.5 1.6 1.6 1.6 -0.2 1.7
Neck or shoulder pain in last month 0.4 0.6 1.7 0.7 0.7 0.8 0.4 0.5 0.6 0.6 -1.1 1.0 0.3 0.6 0.9 1.0 1.3 -1.0 0.7 1.0 0.3 1.1 -0.8 -0.8 -0.9 -0.7 -0.6 -0.6 -0.1 -0.5
Medication: Blood pressure 0.4 0.8 1.5 -0.9 -0.9 -0.9 -1.1 -1.0 -0.6 -0.5 0.9 -0.4 -0.8 -1.1 -0.9 -0.8 -0.6 0.8 -0.7 -1.1 -1.2 -0.8 0.9 0.9 0.7 0.9 1.0 1.0 0.6 0.8
Angina (self-reported) 3.2 4.3 8.6 2.1 2.4 2.2 1.9 1.7 2.9 2.6 -1.9 2.0 2.9 2.2 2.2 2.3 1.5 -2.0 2.2 1.8 1.7 2.0 -2.0 -2.0 -2.1 -1.8 -2.0 -2.0 0.0 -1.5
Migraine (self-reported) 0.1 0.2 0.6 0.3 0.4 0.4 0.3 0.2 0.5 0.5 -0.4 0.5 0.6 0.3 0.4 0.5 0.5 -0.5 -0.0 0.4 0.2 0.5 -0.5 -0.6 -0.1 -0.4 -0.1 -0.0 0.2 -0.8
Medication: Ibuprofen 1.5 1.8 3.0 1.3 1.3 1.2 1.7 1.0 1.6 1.7 -1.6 1.7 1.2 1.3 1.2 1.3 0.9 -1.4 1.5 1.2 1.4 1.6 -1.2 -1.2 -0.7 -1.5 -1.4 -1.4 -1.1 -1.3
Medication: Allopurinol 0.1 0.1 0.6 0.0 0.5 0.3 0.7 0.4 0.6 0.4 0.0 -0.8 0.5 0.4 0.2 0.3 0.1 -0.0 0.4 -0.1 0.5 0.1 -0.0 -0.0 0.1 -0.0 -0.0 -0.0 0.3 -0.1
Medication: Omeprazole 2.1 2.5 5.5 1.9 1.4 1.9 0.4 1.3 1.0 1.1 -2.4 1.8 1.5 1.3 2.0 1.7 1.4 -1.5 1.7 2.1 1.0 1.9 -1.6 -1.6 -1.5 -1.5 -1.7 -1.7 0.1 -1.4
Medication: Seretide 50 evohaler 0.3 0.3 5.2 -0.2 0.0 -0.3 0.9 -0.1 0.1 0.0 -0.3 -0.1 0.3 -0.0 -0.3 0.1 2.3 0.6 -0.1 0.7 -0.6 0.1 0.4 0.1 0.8 0.0 0.4 0.5 -0.2 0.1
Mean time to correctly identify matches 2.0 3.8 6.4 -2.2 -1.8 -1.9 -1.8 -2.5 -2.0 -1.8 1.4 -1.0 -1.9 -1.8 -2.0 -1.8 -0.1 2.5 -1.7 -1.7 -1.9 -2.2 2.2 2.2 2.1 2.2 2.3 2.3 1.1 2.1
Heart disease (mother) 0.3 0.3 1.0 0.5 0.5 0.6 0.4 0.5 0.6 0.6 -0.8 -0.2 0.6 0.4 0.6 0.7 0.5 -0.3 0.9 0.3 0.9 0.4 -0.6 -0.7 -0.1 -0.4 -0.3 -0.3 0.8 -1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 1.2 0.6 0.7 0.7 1.0 0.8 0.7 0.9 -0.8 0.2 0.2 0.9 0.5 0.8 1.0 -0.5 0.6 0.8 0.3 0.8 -0.7 -0.7 -0.9 -0.8 -0.7 -0.6 -1.1 -0.2
Whole body fat mass 0.4 1.8 10.1 -1.0 -1.2 -1.0 -2.8 -1.0 -1.9 -1.9 1.0 -3.2 -1.5 -1.7 -1.1 -0.3 0.2 1.0 -0.9 0.5 -0.9 -0.3 1.0 0.6 0.4 0.6 1.3 1.4 -0.7 1.3
Leg fat mass (right) 0.4 1.7 8.3 -1.0 -1.3 -1.0 -2.4 -1.0 -1.9 -2.0 1.1 -2.9 -1.4 -1.7 -1.1 -0.3 0.2 1.1 -1.0 0.5 -0.9 -0.3 1.1 0.6 0.8 0.7 1.3 1.4 -0.6 1.2
Arm predicted mass (right) 0.1 0.6 4.6 0.5 0.3 0.4 -2.2 0.4 -0.8 -0.9 -0.4 -1.3 -0.2 -0.2 0.4 0.9 -0.1 -0.6 0.6 1.2 0.4 1.0 -0.6 -0.8 -0.9 -0.8 -0.4 -0.4 -1.1 -0.3
Pulse rate, automated reading 0.3 1.0 3.9 -1.1 -1.0 -1.0 -0.8 -1.2 -0.8 -1.1 1.0 -1.0 -0.8 -1.0 -1.1 -0.4 -0.4 1.3 -0.8 -0.7 -1.1 -0.8 1.3 1.1 0.4 0.9 1.1 1.2 -0.7 2.0
Alcohol intake frequency. 0.3 0.8 3.6 0.8 0.5 0.8 1.5 0.5 0.9 1.1 -1.1 1.9 0.6 0.7 0.9 0.8 1.6 -0.8 0.6 0.8 0.3 0.3 -0.7 -0.6 -0.6 -0.4 -0.7 -0.7 1.1 -0.7
Comparative height size at age 10 1.7 9.2 15.6 3.1 3.3 3.0 1.6 2.6 3.0 3.4 -3.5 3.2 2.3 3.3 3.1 3.0 1.6 -3.7 2.9 2.7 2.8 2.9 -3.7 -3.5 -4.0 -3.2 -3.2 -3.2 -1.2 -3.1
Number of full sisters 0.8 1.0 2.4 -1.1 -0.9 -1.4 -1.5 -1.0 -0.7 -0.8 0.8 -1.0 -0.8 -0.8 -1.2 -1.0 -0.9 0.8 -1.2 -1.0 -1.2 -0.7 1.0 0.8 0.2 0.8 1.2 1.2 -0.6 1.4
Suffer from ‘nerves’ 8.7 13.7 18.7 4.0 3.9 3.9 3.7 4.0 3.9 4.1 -3.4 3.7 3.4 3.8 3.9 3.8 2.9 -3.9 4.1 3.5 2.7 4.3 -3.8 -3.8 -2.4 -4.1 -4.1 -4.0 -1.9 -4.0
Overall health rating 1.2 2.5 10.6 1.5 1.6 1.5 1.7 1.3 1.8 2.0 -1.8 1.4 1.5 1.6 1.6 1.9 3.3 -1.1 1.4 1.8 0.9 1.4 -1.4 -1.5 -1.7 -1.1 -1.0 -1.0 0.8 -1.0
Chest pain or discomfort 0.7 1.1 2.9 1.0 1.1 1.0 0.6 0.6 1.2 1.3 -1.4 1.7 0.8 1.0 1.0 1.5 1.2 -0.6 1.2 1.2 0.2 1.1 -1.0 -1.1 -1.1 -0.9 -0.8 -0.8 -0.1 -0.8
Had major operations 0.1 0.1 0.3 0.0 -0.0 0.0 -0.6 -0.2 -0.3 -0.0 -0.4 -0.0 -0.3 -0.2 -0.1 -0.3 -0.3 0.4 0.6 0.0 -0.4 0.2 0.3 0.1 0.4 -0.1 -0.1 -0.0 -0.6 0.2
Age at last live birth 1.8 2.6 5.0 -1.7 -1.7 -1.6 -2.0 -1.6 -1.8 -1.8 1.7 -0.6 -1.8 -1.6 -1.6 -2.0 -2.2 1.4 -1.6 -1.4 -0.9 -1.5 1.7 1.9 2.1 1.3 1.2 1.2 -0.5 1.3
Family relationship satisfaction 4.3 5.3 8.8 -2.6 -2.7 -2.9 -2.0 -2.3 -1.7 -2.0 2.6 -1.1 -2.0 -2.2 -2.7 -2.9 -0.5 2.8 -3.0 -1.7 -1.7 -2.6 2.6 2.6 2.2 2.5 2.5 2.5 0.4 2.5
Leg pain on walking 0.1 0.1 0.8 -0.1 0.0 0.1 -0.0 -0.3 0.3 0.1 -0.1 0.6 -0.1 -0.2 -0.0 0.1 0.3 0.4 0.0 0.4 0.3 -0.3 0.0 0.0 -0.2 0.4 0.3 0.3 0.9 -0.1
Qualifications: NVQ or HND or HNC or equivalent 0.6 0.7 1.5 0.9 0.8 0.7 0.8 1.2 0.4 0.6 -0.9 0.4 0.3 0.9 0.8 0.8 -0.2 -0.9 1.0 0.9 1.2 0.7 -1.0 -1.1 -0.9 -0.9 -0.8 -0.8 -0.1 -1.1
Commuting to job workplace: Car/motor vehicle 1.0 1.2 2.0 1.1 1.1 1.2 0.8 1.0 1.3 0.9 -1.3 0.8 1.4 1.2 1.1 1.4 0.4 -1.1 1.0 1.2 1.1 0.7 -1.1 -1.1 -1.2 -0.6 -0.9 -0.9 1.3 -1.1
Illness, injury, bereavement, stress in last 2 years 0.1 0.1 0.9 0.2 0.1 -0.1 -0.5 0.4 -0.2 0.1 -0.1 0.8 0.0 0.0 -0.0 -0.4 0.4 -0.2 0.2 0.0 0.0 0.1 -0.3 -0.1 -0.6 -0.4 -0.6 -0.6 -0.9 -0.0
Medication: Aspirin 1.8 2.3 4.6 1.6 1.6 1.6 0.9 1.3 1.7 1.7 -2.1 1.0 1.3 1.6 1.5 2.0 1.4 -1.6 1.7 1.9 0.8 1.3 -1.8 -1.9 -1.8 -1.4 -1.2 -1.2 0.4 -1.7
Supplements: Vitamin C 2.2 2.6 4.5 1.7 1.5 1.9 1.9 1.9 1.4 1.5 -0.7 1.4 1.3 1.5 1.9 2.0 1.0 -1.8 1.5 1.9 2.1 2.1 -1.5 -1.6 -0.5 -1.8 -1.7 -1.6 -0.7 -1.8
Knee pain experienced in last month 0.2 0.3 3.8 0.1 0.2 0.4 0.3 -0.2 0.3 0.0 -0.4 0.1 0.5 -0.1 0.4 0.3 1.6 -0.1 0.1 0.5 -0.4 -0.0 -0.0 -0.1 0.2 0.4 0.2 0.2 2.0 -0.4
Hypertension (Self-reported) 0.1 0.3 1.3 0.6 0.0 0.3 -1.2 0.3 -0.1 0.3 -0.2 -0.7 0.1 -0.1 0.5 0.5 0.7 -0.6 0.1 1.0 0.1 0.5 -0.5 -0.6 -0.1 -0.3 -0.3 -0.3 0.9 -0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.8 2.2 4.2 1.7 1.5 2.0 1.3 1.5 1.5 1.5 -1.0 1.2 1.7 1.3 2.0 1.8 1.5 -1.6 1.5 1.7 1.3 1.5 -1.2 -1.3 -1.0 -0.9 -1.3 -1.3 1.6 -1.2
Illnesses of father: Heart disease 0.4 0.6 1.5 -1.0 -0.8 -1.1 -0.1 -0.4 -0.3 -0.4 1.0 0.1 -0.6 -0.7 -1.1 -1.2 -0.9 1.0 -1.0 -0.7 -0.9 -0.9 0.7 0.7 0.5 0.6 0.7 0.8 -0.9 0.7
Illnesses of siblings: Diabetes 6.7 8.2 12.5 -3.1 -3.2 -3.4 -2.1 -2.9 -3.0 -2.8 2.4 -2.7 -3.2 -3.1 -3.4 -3.1 -0.8 2.9 -2.8 -3.1 -3.5 -3.0 3.0 3.0 2.4 2.9 3.1 3.1 0.5 2.8
Smoking status: Previous 0.7 1.0 4.0 0.9 1.3 1.0 0.6 0.4 1.2 0.9 -1.3 0.4 1.5 1.0 0.9 1.2 2.0 -0.9 1.5 1.0 0.9 1.1 -0.6 -0.8 -0.5 -0.7 -0.7 -0.6 0.0 -0.4
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.3 3.0 -0.0 0.1 -0.2 -1.7 -0.0 -0.6 -0.3 -0.1 -0.9 -0.7 0.2 -0.2 0.0 -0.7 -0.3 -0.2 0.3 -0.1 0.1 -0.3 -0.4 -1.4 -0.0 0.1 0.1 -0.5 0.3
Whole body fat-free mass 0.1 0.6 7.1 0.3 -0.0 0.2 -2.7 0.0 -1.1 -1.1 -0.2 -1.4 -0.5 -0.5 0.2 0.5 -0.3 -0.3 0.3 0.9 0.1 0.7 -0.3 -0.5 -0.9 -0.4 -0.1 -0.1 -0.7 0.1
Leg fat-free mass (right) 0.3 1.8 13.5 -0.9 -1.1 -1.0 -3.7 -0.9 -2.1 -2.1 0.9 -2.4 -1.5 -1.6 -1.0 -0.6 -1.0 0.8 -0.8 0.0 -1.1 -0.5 0.8 0.6 -0.3 0.7 1.0 1.0 -0.5 1.4
Arm fat percentage (left) 1.5 5.8 20.6 -2.2 -2.5 -2.2 -3.6 -2.0 -3.3 -3.2 2.3 -4.5 -2.7 -3.0 -2.3 -1.6 -0.1 2.4 -2.1 -0.6 -2.0 -1.6 2.3 1.9 1.5 1.9 2.6 2.7 -0.1 2.6
Average weekly red wine intake 0.2 0.3 2.7 -0.5 -0.3 -0.6 -0.6 0.1 -0.3 -0.3 0.2 -0.7 -0.7 -0.3 -0.6 -0.8 -1.6 0.4 -0.4 -0.9 -0.4 -0.4 0.2 0.2 -0.6 0.3 0.5 0.5 -0.2 0.4
Handedness (chirality/laterality): Left-handed 1.2 1.4 2.8 -1.1 -1.7 -1.1 -0.6 -0.8 -1.4 -1.3 1.1 -1.6 -1.0 -1.3 -1.1 -1.2 -0.5 1.4 -1.5 -1.4 -1.5 -1.1 1.2 1.1 1.2 1.2 1.2 1.2 0.7 1.0
Mood swings 0.5 0.9 1.9 0.9 1.1 0.8 0.5 1.0 1.1 1.1 -1.0 1.0 0.9 1.1 0.8 1.2 1.2 -0.9 1.1 1.4 0.0 1.2 -0.9 -1.1 -1.2 -0.9 -0.6 -0.5 -0.3 -0.6
Loneliness, isolation 0.2 0.3 3.0 -0.4 -0.3 -0.3 0.2 -0.5 0.0 -0.4 0.9 0.1 0.5 -0.3 -0.2 -0.3 0.7 0.5 -0.7 0.3 -0.8 -0.1 0.7 0.7 1.7 0.2 0.3 0.3 -0.1 0.2
Long-standing illness, disability or infirmity 0.2 0.2 1.0 -0.3 -0.3 -0.4 -0.5 -0.6 -0.1 -0.0 -0.2 0.1 -0.4 -0.3 -0.4 -0.2 1.0 0.8 0.0 0.2 -0.8 -0.4 0.4 0.3 0.3 0.5 0.5 0.5 1.0 0.3
Ever had bowel cancer screening 0.7 0.8 2.1 1.0 1.0 1.3 0.6 0.4 0.8 0.9 -1.3 0.8 1.2 0.8 1.3 1.4 1.0 -0.7 1.1 0.1 0.9 0.8 -0.7 -0.9 -0.2 -0.7 -0.7 -0.7 1.0 -0.9
Diabetes diagnosed by doctor 9.0 14.7 18.8 -4.0 -4.2 -3.8 -4.2 -4.2 -4.2 -4.3 4.1 -3.9 -3.5 -4.3 -3.9 -3.9 -1.1 4.2 -3.9 -3.2 -3.8 -4.1 4.1 4.2 4.0 4.0 3.8 3.8 1.6 3.6
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 0.7 -0.4 -0.3 -0.2 -0.5 -0.8 -0.5 -0.5 0.4 0.1 -0.4 -0.4 -0.3 -0.2 0.8 0.3 -0.5 -0.1 -0.6 -0.3 0.4 0.3 0.0 0.4 0.5 0.5 0.3 0.7
Friendships satisfaction 3.3 4.1 10.8 -2.1 -2.2 -2.1 -1.4 -1.6 -1.5 -1.5 3.3 -1.1 -1.3 -1.7 -2.0 -2.6 0.2 2.3 -2.8 -1.4 -1.6 -2.4 2.2 2.2 1.7 2.5 2.2 2.1 2.2 2.0
Qualifications: nursing, teaching 0.8 1.3 4.2 -1.1 -1.3 -1.1 -2.1 -1.2 -1.4 -1.3 1.2 -1.6 -1.0 -1.2 -1.1 -1.3 -0.4 1.1 -1.3 -0.9 -0.5 -0.8 0.8 0.9 1.6 0.7 1.0 1.0 -0.2 0.1
Commuting to job workplace: Walk 2.3 2.4 4.1 -1.7 -1.8 -1.5 -0.8 -1.7 -1.0 -1.3 2.0 -1.1 -0.9 -1.6 -1.6 -1.6 -0.2 2.0 -2.0 -1.8 -1.6 -1.7 1.8 1.8 1.4 1.8 1.7 1.7 0.7 1.8
Eye problems/disorders: Cataract 1.2 1.4 2.7 1.2 1.1 1.3 1.6 1.4 1.3 1.5 -1.0 0.5 0.8 0.9 1.3 1.2 0.2 -1.1 1.5 0.8 1.1 1.3 -1.2 -1.2 -1.2 -1.4 -1.3 -1.2 -1.2 -0.8
Mouth/teeth dental problems: Mouth ulcers 8.5 13.5 17.3 4.0 3.9 4.1 3.2 3.4 3.8 4.2 -4.0 3.8 3.4 3.5 4.0 4.0 2.1 -3.8 4.2 3.1 4.1 4.0 -3.8 -3.9 -3.3 -3.9 -3.9 -3.9 -1.3 -3.5
Medication for cholesterol 1.8 2.7 6.0 -1.9 -1.4 -1.7 0.5 -2.3 -1.1 -1.5 1.7 0.5 -1.3 -1.0 -1.8 -2.4 -1.5 1.7 -1.8 -2.2 -1.4 -2.2 1.6 2.1 1.7 1.8 1.4 1.3 0.5 1.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.8 0.9 7.5 0.5 0.9 0.7 1.6 0.2 1.4 1.2 -0.2 1.2 1.2 1.1 0.8 0.8 2.7 -0.5 0.4 1.1 0.2 0.5 -0.5 -0.5 -1.3 -0.2 -0.3 -0.3 0.7 0.3
Back pain experienced in last month 2.9 4.3 16.1 1.8 2.1 1.8 2.0 2.1 2.4 2.2 -2.1 2.0 2.1 2.1 1.8 1.6 4.0 -1.8 1.7 3.6 1.7 1.7 -1.9 -1.9 -2.3 -1.5 -1.5 -1.6 0.3 -1.5
Mineral and other dietary supplements 0.3 0.4 1.4 0.4 0.7 0.3 0.0 0.3 1.1 1.0 -1.2 0.5 0.7 0.6 0.2 0.2 0.3 -0.4 0.6 0.4 0.2 0.6 -0.5 -0.5 -0.7 -0.7 -0.6 -0.5 -1.1 -0.3
Breast cancer (self-reported) 0.3 0.4 1.7 0.5 0.6 0.4 0.1 0.4 0.0 0.3 -1.1 1.3 0.0 0.5 0.4 0.2 -0.3 -0.6 0.8 0.8 0.3 0.3 -0.8 -0.5 -1.1 -0.5 -0.8 -0.8 -0.5 -0.5
Asthma (self-reported) 0.1 0.3 2.8 -0.7 -0.3 -0.8 0.5 0.0 0.2 0.1 0.1 0.3 -0.2 -0.3 -0.9 -0.5 -0.4 0.3 -0.3 -0.5 -0.3 -0.0 0.5 0.4 0.4 0.1 0.6 0.7 -1.7 0.6
Osteoporosis (self-reported) 0.5 0.7 2.0 1.0 0.7 1.1 0.5 0.4 0.7 0.8 -1.0 1.1 0.7 0.8 1.1 1.1 0.3 -0.7 0.8 0.5 0.5 0.7 -0.8 -0.9 -0.1 -0.5 -0.7 -0.7 1.4 -1.2
Osteoarthritis (self-reported) 3.9 5.0 7.6 -2.1 -2.4 -2.1 -1.4 -2.2 -2.6 -2.4 2.5 -2.5 -2.4 -2.5 -2.0 -1.8 0.5 2.5 -2.3 -1.3 -2.0 -2.2 2.4 2.3 2.8 2.6 2.5 2.5 2.5 1.7
Medication: Aspirin 1.0 1.3 3.0 1.1 1.1 1.2 0.7 0.8 1.4 1.4 -1.6 0.3 1.1 1.1 1.1 1.6 1.7 -1.1 1.1 1.7 0.5 0.8 -1.2 -1.4 -1.2 -0.8 -0.7 -0.7 1.0 -1.4
Medication: Gliclazide 0.2 0.2 0.9 -0.3 -0.3 -0.3 -0.3 -0.6 -0.6 -0.5 -0.1 -0.4 -0.4 -0.5 -0.3 -0.2 0.9 0.4 -0.1 0.0 -0.7 -0.4 0.2 0.3 0.9 0.3 0.3 0.2 0.6 -0.4
Illnesses of father: None of the above (group 1) 0.7 0.8 1.9 1.0 1.1 1.0 0.3 0.4 0.6 0.8 -1.3 0.5 0.6 1.1 1.0 1.3 0.9 -1.2 1.2 0.7 1.0 0.7 -0.9 -1.0 -1.4 -0.6 -0.7 -0.7 0.8 -0.6
Smoking status: Current 2.6 4.2 8.2 -2.3 -1.9 -2.4 -1.5 -2.5 -1.3 -1.8 1.9 -1.4 -1.7 -1.9 -2.4 -2.1 -0.9 2.4 -2.3 -2.3 -2.9 -2.2 2.3 2.2 1.9 2.1 2.3 2.3 0.5 2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.7 1.5 4.2 -1.5 -1.3 -1.2 0.2 -1.2 -0.7 -0.7 1.8 -0.4 -0.6 -1.1 -1.3 -2.0 -0.9 1.6 -1.6 -1.5 -0.7 -1.8 1.2 1.6 0.9 1.4 1.1 1.0 0.5 1.2
Whole body water mass 0.1 0.6 7.3 0.2 -0.0 0.2 -2.7 0.1 -1.1 -1.1 -0.2 -1.5 -0.4 -0.5 0.2 0.5 -0.2 -0.3 0.2 1.0 0.1 0.7 -0.3 -0.5 -0.9 -0.4 -0.1 -0.1 -0.7 0.1
Leg predicted mass (right) 0.3 1.7 13.1 -0.8 -1.1 -0.9 -3.6 -0.9 -2.1 -2.1 0.9 -2.4 -1.5 -1.5 -1.0 -0.6 -1.0 0.7 -0.8 0.0 -1.0 -0.4 0.7 0.6 -0.4 0.7 0.9 1.0 -0.5 1.3
Arm fat mass (left) 0.8 3.4 16.2 -1.5 -1.8 -1.5 -3.5 -1.4 -2.8 -2.6 1.6 -4.0 -2.1 -2.4 -1.6 -0.9 -0.1 1.5 -1.3 0.1 -1.4 -0.8 1.6 1.1 0.8 1.1 1.8 1.9 -0.6 1.8
Number of self-reported non-cancer illnesses 0.3 0.5 1.8 0.7 0.4 0.7 0.7 0.6 1.1 1.3 -0.7 -0.2 0.8 0.4 0.8 0.9 0.8 -0.6 0.6 0.3 0.2 0.5 -0.8 -0.9 -0.4 -0.4 -0.3 -0.3 1.2 -1.1
Average weekly champagne plus white wine intake 0.1 0.2 0.7 0.1 0.2 0.1 0.5 0.3 0.1 -0.0 0.0 0.8 0.5 0.3 0.1 -0.4 -0.5 -0.1 0.2 0.2 0.7 -0.2 -0.1 0.1 0.8 -0.1 -0.2 -0.3 0.2 -0.9
Miserableness 0.5 0.8 2.4 -1.0 -0.8 -1.0 -0.7 -0.9 -0.4 -0.7 0.7 -0.9 -0.2 -0.7 -1.0 -0.7 -0.4 1.1 -0.8 -1.1 -1.5 -0.9 1.1 1.0 0.7 1.1 1.1 1.1 0.6 1.1
Guilty feelings 0.1 0.2 0.8 -0.4 -0.2 -0.4 -0.2 -0.3 -0.1 -0.3 0.3 0.1 -0.2 -0.2 -0.3 -0.1 0.7 0.6 -0.2 -0.2 -0.9 -0.3 0.5 0.4 0.9 0.4 0.4 0.4 0.1 0.2
Wears glasses or contact lenses 0.3 0.3 1.3 0.1 0.8 0.2 0.9 0.0 1.1 0.9 -1.1 0.7 0.7 0.5 0.0 0.2 0.5 -0.2 1.1 0.1 0.2 0.5 -0.2 -0.3 0.1 -0.4 -0.1 -0.1 -0.7 -0.4
Ever taken oral contraceptive pill 5.0 5.6 11.8 -2.5 -2.4 -2.5 -2.9 -2.5 -2.7 -2.9 1.9 -3.4 -2.4 -2.4 -2.4 -2.2 -1.0 2.2 -2.2 -1.8 -2.9 -1.8 2.5 2.4 2.4 2.2 2.4 2.5 0.1 2.2
Hearing aid user 0.2 0.3 1.4 -0.5 -0.6 -0.5 0.0 -0.4 -0.3 -0.2 -0.2 0.1 -0.6 -0.5 -0.5 -0.2 1.0 0.7 -0.2 0.2 -0.7 -0.4 0.5 0.5 -0.5 0.5 0.5 0.6 -0.2 1.2
Mother’s age at death 1.3 1.6 4.2 -1.2 -1.2 -1.1 -0.6 -1.7 -1.4 -1.5 1.0 -0.8 -1.4 -1.2 -1.1 -1.2 -1.7 1.3 -1.2 -2.0 -1.0 -1.4 1.4 1.5 1.5 1.3 1.0 1.0 0.8 1.1
Financial situation satisfaction 2.4 3.0 6.5 1.6 1.7 1.9 2.1 1.8 2.2 2.1 -1.3 1.9 1.9 1.7 1.9 2.1 2.3 -1.3 1.3 1.5 2.3 0.9 -1.5 -1.6 -1.8 -0.7 -0.9 -1.0 2.6 -1.2
Tinnitus: Yes, now most or all of the time 1.9 2.2 3.4 1.4 1.6 1.4 1.3 1.6 1.8 1.8 -1.8 1.1 1.2 1.4 1.4 1.6 1.3 -1.5 1.6 1.7 1.1 1.5 -1.7 -1.7 -1.3 -1.5 -1.3 -1.3 -0.2 -1.8
Commuting to job workplace: Public transport 0.5 0.6 2.6 -0.8 -0.6 -1.1 0.1 -0.6 -0.4 -0.4 0.5 -1.0 -1.1 -0.7 -1.1 -0.8 -0.1 0.5 -0.1 -1.2 -1.1 -0.4 0.7 0.6 -0.1 0.3 0.6 0.7 -1.6 1.2
Eye problems/disorders: Glaucoma 1.5 1.7 3.4 1.4 1.3 1.5 0.8 1.2 0.9 1.1 -1.3 0.2 0.8 1.2 1.4 1.6 0.9 -1.4 1.5 1.6 1.9 1.6 -1.5 -1.6 -0.7 -1.6 -1.2 -1.2 -0.6 -1.8
Medication: Blood pressure 0.3 0.5 2.0 0.8 0.3 0.5 -0.8 0.8 0.6 0.8 -0.6 -0.8 0.4 0.2 0.7 0.9 1.4 -0.6 0.4 1.2 0.4 0.8 -0.6 -0.9 -0.6 -0.7 -0.4 -0.4 -0.1 -0.6
Pain type(s) experienced in last month: Hip pain 2.9 3.7 6.6 2.0 1.6 1.9 2.2 2.2 1.8 1.9 -1.8 1.7 1.4 1.9 2.0 1.9 2.5 -2.2 1.3 2.6 1.8 1.9 -2.1 -2.1 -2.1 -1.6 -1.8 -1.8 0.5 -2.0
Supplements: Fish oil (including cod liver oil) 0.7 1.0 2.8 -1.0 -1.1 -0.8 -0.6 -0.8 -1.0 -1.1 1.7 -0.8 -0.8 -0.9 -0.8 -0.8 -0.7 1.0 -1.2 -0.9 -0.8 -1.2 1.0 1.1 1.0 1.1 1.1 1.1 0.9 0.9
High cholesterol (Self-reported) 0.8 1.3 5.1 1.1 0.9 1.2 1.0 1.1 1.1 1.3 -0.9 -0.3 1.2 0.9 1.3 1.4 2.3 -1.0 0.8 1.7 0.8 1.5 -0.9 -1.1 -1.0 -1.3 -1.1 -1.0 -1.0 -0.6
Medication: Bendroflumethiazide 0.3 0.4 2.0 -0.5 -0.6 -0.6 -1.4 -0.4 -0.4 -0.6 1.1 -0.0 -0.4 -0.8 -0.5 -0.5 -0.8 0.7 -0.9 -0.4 0.1 -0.5 0.7 0.7 0.6 0.5 0.4 0.4 0.1 0.8
Medication: Paracetamol 1.9 3.0 4.7 1.7 1.7 1.9 1.9 1.8 2.2 2.1 -1.5 2.1 2.1 1.8 1.8 1.9 2.2 -1.8 1.8 1.4 1.3 1.6 -1.6 -1.7 -1.2 -1.4 -1.5 -1.5 0.5 -1.7
Medication: Lisinopril 0.5 0.6 2.6 -0.7 -0.8 -0.9 -0.7 -0.2 -0.9 -0.8 0.6 -0.9 -1.0 -0.8 -0.9 -1.3 -1.0 0.2 -0.6 -0.5 -0.5 -0.1 0.6 0.8 1.4 0.1 0.1 0.2 -1.6 0.1
Medication: Atorvastatin 0.7 0.9 2.1 0.8 1.0 0.6 1.3 1.4 0.9 1.0 -0.9 0.4 0.8 0.9 0.7 0.8 0.9 -0.7 1.0 1.2 0.8 1.1 -0.9 -1.0 -0.6 -1.1 -0.9 -0.8 -1.2 -1.0
Illnesses of father: High blood pressure 1.1 1.3 2.0 -1.2 -1.1 -1.3 -1.0 -1.0 -1.3 -1.2 1.3 -1.4 -1.1 -1.3 -1.3 -1.4 -1.3 1.2 -1.1 -1.0 -1.3 -1.2 1.0 1.1 1.1 1.1 1.1 1.1 0.2 0.8
Alcohol drinker status: Never 1.8 2.2 3.6 -1.5 -1.7 -1.5 -1.3 -1.4 -1.8 -1.6 0.7 -1.8 -1.9 -1.7 -1.5 -1.0 -0.8 1.6 -1.1 -1.1 -1.7 -1.8 1.3 1.3 0.8 1.7 1.8 1.8 1.6 1.2
Ever smoked 0.1 0.2 1.6 0.0 0.5 0.2 -0.1 -0.6 0.6 0.3 -0.6 0.0 0.7 0.3 0.1 0.3 1.3 -0.1 0.5 0.0 -0.3 0.2 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.3
Basal metabolic rate 0.1 0.7 8.0 0.2 -0.1 0.1 -2.8 0.0 -1.3 -1.2 -0.1 -1.8 -0.6 -0.6 0.1 0.5 -0.1 -0.2 0.2 1.1 -0.0 0.6 -0.2 -0.4 -0.9 -0.3 -0.0 0.1 -0.8 0.2
Leg fat percentage (left) 0.5 1.8 8.5 -1.2 -1.4 -1.1 -1.7 -1.1 -1.7 -1.9 1.3 -2.9 -1.3 -1.7 -1.1 -0.4 0.3 1.4 -1.3 0.2 -1.1 -0.6 1.3 0.9 1.2 0.9 1.5 1.7 -0.2 1.2
Arm fat-free mass (left) 0.2 1.0 3.2 1.0 0.7 0.8 -1.6 0.9 -0.4 -0.4 -0.8 -1.0 0.1 0.2 0.8 1.3 0.0 -1.1 0.9 1.8 0.8 1.5 -1.1 -1.3 -1.3 -1.3 -0.9 -0.8 -1.4 -0.8
Number of operations (self-reported) 4.7 7.0 11.1 3.0 2.8 3.1 1.4 2.6 2.4 2.6 -3.1 2.0 2.4 2.5 3.0 2.9 1.4 -2.6 3.3 3.1 3.0 2.6 -2.9 -3.0 -2.2 -2.7 -2.8 -2.8 0.1 -3.0
Average weekly beer plus cider intake 0.1 0.2 1.0 -0.4 0.1 -0.4 -0.3 -0.2 -0.2 -0.5 0.4 -1.0 0.1 -0.2 -0.3 -0.0 -0.2 0.1 -0.2 -0.4 0.4 -0.1 0.4 0.2 -0.0 0.1 0.6 0.7 -0.6 0.8
Irritability 0.8 1.4 2.9 1.2 1.1 1.1 1.2 1.0 1.7 1.6 -1.3 1.6 1.3 1.3 1.1 1.4 1.6 -0.6 1.1 1.0 0.8 0.7 -1.0 -1.1 -1.7 -0.6 -0.8 -0.8 1.1 -0.6
Risk taking 1.2 1.8 2.8 -1.6 -1.5 -1.5 -0.6 -1.7 -1.4 -1.6 1.3 -0.9 -1.7 -1.6 -1.5 -1.6 -0.4 1.3 -1.6 -0.9 -0.8 -1.1 1.4 1.5 1.0 1.2 1.4 1.4 -0.4 1.6
Ever had prostate specific antigen (PSA) test 0.2 0.2 0.7 0.4 0.6 0.6 -0.2 0.3 0.5 0.7 -0.9 0.7 0.4 0.4 0.5 0.2 0.0 -0.4 0.7 -0.1 0.1 0.5 -0.4 -0.4 0.2 -0.4 -0.4 -0.4 0.1 -0.8
Fractured/broken bones in last 5 years 1.4 1.8 5.7 1.3 1.4 1.5 1.5 0.9 1.9 1.2 -1.2 1.6 2.4 1.5 1.5 1.7 1.8 -0.8 1.2 1.4 0.8 1.0 -0.9 -1.1 -0.8 -0.8 -0.9 -0.9 1.2 -0.9
Age started oral contraceptive pill 3.3 4.1 5.8 2.3 2.1 2.2 0.8 2.4 1.8 2.0 -1.8 2.2 1.9 2.0 2.3 2.4 0.5 -1.9 2.3 1.9 2.2 1.8 -2.4 -2.3 -2.3 -2.0 -2.2 -2.3 -0.0 -2.2
Diastolic blood pressure, automated reading 2.3 7.1 18.2 -2.4 -2.9 -2.5 -4.3 -2.4 -3.5 -3.4 2.2 -3.8 -3.0 -3.2 -2.6 -2.0 -2.0 2.5 -2.1 -2.1 -2.1 -2.3 2.5 2.2 1.6 2.6 2.8 2.8 1.3 2.5
Ever depressed for a whole week 0.3 0.4 1.9 0.5 0.7 0.3 0.9 0.4 0.8 0.6 0.0 1.4 0.6 0.8 0.4 0.1 -0.4 -0.5 0.1 0.3 0.5 1.0 -0.2 -0.2 0.6 -0.7 -0.7 -0.7 -1.0 -0.5
Unable to work because of sickness or disability 0.9 1.1 4.7 -0.9 -1.0 -0.7 -0.3 -1.1 -0.5 -0.4 0.3 -0.1 -0.3 -1.0 -0.8 -0.6 1.6 1.5 -0.7 -0.5 -1.5 -1.3 1.1 1.1 -0.7 1.5 1.2 1.1 1.6 2.2
Commuting to job workplace: Cycle 1.6 2.0 4.6 -1.6 -1.5 -1.6 -1.2 -1.7 -1.3 -1.1 1.1 0.2 -1.5 -1.5 -1.6 -1.6 -1.1 1.3 -1.4 -1.6 -1.3 -1.3 1.6 1.7 0.8 1.3 1.3 1.3 -0.8 2.1
Myopia 2.1 3.0 8.2 1.7 1.9 1.7 1.4 1.4 2.4 2.1 -1.8 1.3 2.5 1.9 1.8 1.9 2.1 -1.3 1.8 0.9 1.5 0.9 -1.8 -1.8 -2.9 -0.9 -1.2 -1.3 1.8 -1.1
Vascular/heart problems diagnosed by doctor 0.1 0.3 0.9 -0.8 -0.3 -0.5 0.7 -0.4 -0.4 -0.6 0.5 0.5 -0.5 -0.1 -0.7 -0.8 -0.3 0.7 -0.4 -0.8 -0.1 -0.8 0.6 0.8 0.1 0.6 0.4 0.4 -0.5 0.9
Cholesterol lowering medication 1.1 1.6 5.6 1.4 1.1 1.3 -0.1 1.6 0.9 1.1 -1.4 -0.0 1.0 0.8 1.4 1.8 2.0 -1.1 1.2 2.4 0.7 1.8 -1.2 -1.5 -0.7 -1.4 -1.0 -0.9 -0.4 -1.4
Medication: Omeprazole (e.g. Zanprol) 0.4 0.4 1.2 0.9 0.3 1.0 -0.3 0.4 0.0 0.0 -1.1 0.7 0.7 0.3 1.0 0.7 0.9 -0.5 0.7 1.1 0.4 0.8 -0.4 -0.5 -0.4 -0.4 -0.7 -0.7 0.7 -0.3
Pain experienced in last month 0.3 0.5 6.1 -0.1 -0.2 -0.4 -0.7 -0.0 -0.5 -0.6 0.3 -0.8 -0.3 -0.1 -0.5 -0.1 -2.5 0.5 0.0 -1.1 -0.2 -0.2 0.4 0.3 0.6 -0.2 -0.0 0.0 -1.4 0.4
Supplements: Calcium 0.1 0.1 0.7 0.2 -0.0 0.2 0.7 0.1 0.2 0.3 -0.3 -0.5 0.2 0.0 0.3 0.9 0.8 -0.1 0.3 0.1 0.1 0.3 -0.1 -0.3 -0.1 0.0 0.2 0.2 0.8 -0.2
Basal cell carcinoma (self-reported) 1.0 1.1 1.9 -0.9 -1.1 -1.0 -1.0 -1.4 -1.0 -1.0 1.2 -1.1 -1.0 -0.8 -0.9 -1.0 -1.3 1.2 -1.2 -1.1 -1.4 -1.0 1.1 1.1 0.8 1.0 1.0 1.0 0.4 1.3
Heart attack/myocardial infarction (self-reported) 0.1 0.1 0.5 0.4 0.2 0.6 0.3 -0.1 0.6 0.5 -0.1 0.3 0.3 0.2 0.4 0.5 -0.2 -0.2 0.5 -0.5 0.0 0.2 -0.2 -0.2 -0.6 -0.0 -0.2 -0.2 0.7 0.1
Deep venous thrombosis (DVT) (self-reported) 0.1 0.2 1.1 0.3 0.2 0.4 -0.8 0.1 -0.2 -0.0 0.3 0.5 -0.2 0.0 0.4 0.3 -1.0 -0.3 0.3 -0.2 0.5 0.3 -0.4 -0.3 -0.2 -0.5 -0.5 -0.5 -0.5 -0.4
Heart disease (siblings) 0.1 0.1 0.3 0.2 0.2 0.2 -0.5 -0.0 0.2 0.5 -0.5 0.3 -0.1 0.5 0.2 0.2 0.5 -0.4 0.1 0.3 -0.6 0.3 -0.5 -0.5 -0.5 -0.3 -0.0 -0.0 -0.3 -0.6
Alcohol drinker status: Previous 0.6 0.7 2.4 -0.7 -0.9 -0.8 -0.2 -1.2 -0.2 -0.5 1.1 0.1 -0.3 -0.7 -0.8 -1.1 1.3 1.1 -1.1 -0.2 -0.8 -0.8 1.0 1.1 0.1 1.0 0.7 0.7 0.6 1.6
Pack years of smoking 0.2 0.3 1.2 0.3 0.6 0.4 0.5 0.1 0.6 0.6 -0.3 1.1 0.5 0.5 0.4 0.5 1.0 -0.1 0.5 0.5 0.1 0.4 -0.2 -0.2 -0.5 -0.5 -0.4 -0.4 -1.0 0.3
Impedance of whole body 2.0 10.2 21.3 3.1 3.4 2.9 4.6 2.9 4.3 4.6 -3.4 4.1 3.1 4.0 3.0 2.6 1.5 -3.2 3.0 1.7 3.1 2.6 -3.2 -3.0 -2.7 -2.9 -3.3 -3.3 -0.7 -3.1
Leg fat mass (left) 0.6 2.2 10.3 -1.2 -1.5 -1.2 -2.7 -1.2 -2.1 -2.2 1.3 -3.2 -1.6 -1.9 -1.3 -0.5 -0.2 1.3 -1.2 0.2 -1.2 -0.5 1.3 0.8 0.8 0.9 1.6 1.7 -0.6 1.4
Arm predicted mass (left) 0.2 0.8 3.0 0.8 0.5 0.6 -1.7 0.7 -0.6 -0.7 -0.6 -1.2 0.0 0.0 0.7 1.2 0.1 -0.9 0.7 1.5 0.6 1.3 -0.9 -1.1 -1.1 -1.0 -0.6 -0.6 -1.0 -0.6