[Hub]/) : Traits : BMI : ← →

chr5:111,499,732-113,626,035

Best TWAS P=6.77e-10 · Best GWAS P=1.3e-09 conditioned to 0.0184

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	SRP19	0.08	0.06	lasso	5	0.07	1.3e-08	5.0	-5.2	2.3e-07	-0.38	0.29	0.71	FALSE
2	GTEx	Adipose Subcutaneous	REEP5	0.10	0.09	lasso	2	0.05	2.8e-05	5.7	5.7	1.4e-08	0.41	0.03	0.97	FALSE
3	GTEx	Adipose Visceral Omentum	REEP5	0.09	0.05	lasso	5	0.02	4.9e-02	5.2	5.5	2.9e-08	0.37	0.09	0.76	FALSE
4	GTEx	Artery Aorta	REEP5	0.17	0.07	lasso	13	0.10	4.2e-06	5.6	5.3	8.7e-08	0.36	0.15	0.85	FALSE
5	GTEx	Artery Tibial	YTHDC2	0.17	0.09	lasso	9	0.08	3.9e-07	5.2	5.8	6.8e-09	0.26	0.29	0.70	TRUE
6	GTEx	Artery Tibial	REEP5	0.17	0.12	lasso	5	0.13	3.0e-10	5.3	5.5	3.6e-08	0.37	0.06	0.94	FALSE
7	GTEx	Colon Transverse	REEP5	0.12	0.14	lasso	2	0.14	4.4e-07	5.2	5.2	1.8e-07	0.34	0.26	0.72	FALSE
8	GTEx	Esophagus Mucosa	REEP5	0.19	0.10	lasso	5	0.09	1.5e-06	5.2	5.3	9.0e-08	0.36	0.18	0.76	FALSE
9	GTEx	Nerve Tibial	REEP5	0.16	0.13	lasso	3	0.10	9.2e-08	5.3	5.5	3.9e-08	0.41	0.15	0.85	FALSE
10	GTEx	Pituitary	REEP5	0.19	0.02	enet	16	0.02	1.1e-01	5.3	5.7	9.9e-09	0.54	0.08	0.34	FALSE
11	GTEx	Skin Not Sun Exposed Suprapubic	REEP5	0.11	0.10	lasso	7	0.10	6.3e-06	5.7	6.1	9.4e-10	0.44	0.05	0.94	TRUE
12	GTEx	Skin Sun Exposed Lower leg	REEP5	0.08	0.05	lasso	4	0.03	1.9e-03	5.7	5.3	1.1e-07	0.43	0.06	0.93	FALSE
13	GTEx	Skin Sun Exposed Lower leg	CTC-487M23.5	0.17	0.07	lasso	6	0.06	7.7e-06	5.1	5.2	1.9e-07	0.37	0.26	0.74	FALSE
14	GTEx	Skin Sun Exposed Lower leg	CTC-487M23.7	0.06	0.07	lasso	1	0.04	2.4e-04	5.1	5.1	3.0e-07	0.36	0.18	0.76	FALSE
15	GTEx	Testis	REEP5	0.22	0.14	lasso	5	0.14	6.6e-07	5.2	5.4	8.0e-08	0.33	0.20	0.77	FALSE
16	METSIM	Adipose	REEP5	0.05	0.00	bslmm	475	0.01	6.8e-03	5.2	6.2	6.8e-10	0.60	0.10	0.85	TRUE
17	NTR	Blood	REEP5	0.03	0.04	lasso	9	0.04	3.3e-12	5.6	6.0	2.4e-09	0.37	0.07	0.93	FALSE
18	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	APC	0.04	0.02	blup	75	0.02	4.8e-03	5.3	5.7	1.0e-08	0.26	0.02	0.80	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	APC	0.03	0.02	blup	77	0.02	5.2e-03	5.4	5.5	3.6e-08	0.32	0.02	0.64	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	SRP19	0.05	0.04	lasso	3	0.04	3.7e-05	5.3	-5.3	9.0e-08	-0.39	0.04	0.95	FALSE
21	The Cancer Genome Atlas	Stomach Adenocarcinoma	REEP5	0.03	0.02	blup	47	0.03	4.1e-03	5.6	5.1	2.9e-07	0.39	0.02	0.78	FALSE