Best TWAS P=3.33e-11 · Best GWAS P=8.95e-19 conditioned to 5.48e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | INADL | 0.15 | 0.06 | lasso | 5 | 0.05 | 1.7e-04 | 6.12 | -6.6 | 3.3e-11 | 0.81 | 0.07 | 0.38 | TRUE |
| 2 | GTEx | Esophagus Muscularis | TM2D1 | 0.12 | 0.03 | lasso | 3 | 0.04 | 3.2e-03 | 4.57 | 6.2 | 4.2e-10 | -0.55 | 0.02 | 0.87 | FALSE |
| 3 | GTEx | Muscle Skeletal | INADL | 0.12 | 0.00 | enet | 16 | 0.01 | 5.3e-02 | 0.11 | -5.5 | 4.6e-08 | 0.48 | 0.09 | 0.35 | FALSE |
| 4 | METSIM | Adipose | L1TD1 | 0.17 | 0.07 | enet | 23 | 0.10 | 2.7e-15 | -4.44 | -5.5 | 3.8e-08 | 0.11 | 1.00 | 0.00 | TRUE |
| 5 | The Cancer Genome Atlas | Colon Adenocarcinoma | INADL | 0.18 | 0.01 | blup | 240 | 0.06 | 2.2e-04 | -4.87 | -5.6 | 1.9e-08 | 0.32 | 0.04 | 0.34 | FALSE |