[Hub]/) : Traits : BMI : ← →

chr1:45,100,098-51,180,660

Best TWAS P=2.89e-15 · Best GWAS P=3.93e-20 conditioned to 1.13e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	MUTYH	0.04	0.00	enet	23	0.00	8.5e-01	-3.4	6.2	6.7e-10	-0.02	0.08	0.56	FALSE
2	GTEx	Adipose Subcutaneous	RP11-767N6.2	0.03	0.03	enet	6	0.04	3.0e-04	-4.3	-6.1	9.7e-10	-0.04	0.22	0.39	FALSE
3	GTEx	Adipose Visceral Omentum	PIK3R3	0.07	0.02	lasso	3	0.04	4.6e-03	-5.3	-5.3	1.0e-07	-0.01	0.42	0.20	FALSE
4	GTEx	Adipose Visceral Omentum	GPBP1L1	0.10	0.04	lasso	6	0.06	3.4e-04	4.2	5.4	8.5e-08	0.04	0.82	0.15	FALSE
5	GTEx	Artery Tibial	GPBP1L1	0.04	0.04	enet	7	0.03	2.2e-03	-5.3	5.3	1.3e-07	0.04	0.71	0.10	FALSE
6	GTEx	Breast Mammary Tissue	GPBP1L1	0.06	0.02	lasso	5	0.00	2.4e-01	-5.1	5.4	5.9e-08	0.02	0.22	0.23	FALSE
7	GTEx	Cells Transformed fibroblasts	IPP	0.04	0.08	lasso	1	0.08	2.3e-06	-5.2	5.2	2.3e-07	0.04	0.73	0.22	FALSE
8	GTEx	Colon Transverse	GPBP1L1	0.06	0.01	lasso	6	0.01	8.3e-02	-5.0	5.3	1.5e-07	0.04	0.34	0.12	FALSE
9	GTEx	Esophagus Mucosa	GPBP1L1	0.04	0.02	lasso	3	0.02	1.5e-02	-5.0	5.3	9.4e-08	0.04	0.21	0.12	FALSE
10	GTEx	Esophagus Muscularis	CCDC17	0.04	0.04	lasso	6	0.01	9.1e-02	-5.2	5.2	2.6e-07	0.04	0.45	0.13	FALSE
11	GTEx	Lung	GPBP1L1	0.04	0.02	enet	14	0.02	5.8e-03	-5.0	5.3	1.4e-07	0.05	0.51	0.18	FALSE
12	GTEx	Muscle Skeletal	GPBP1L1	0.03	0.02	enet	19	0.03	7.2e-04	-5.2	5.1	2.8e-07	0.03	0.51	0.14	FALSE
13	GTEx	Skin Sun Exposed Lower leg	GPBP1L1	0.03	0.00	lasso	5	0.00	4.8e-01	-3.2	5.2	1.9e-07	0.01	0.16	0.06	FALSE
14	GTEx	Skin Sun Exposed Lower leg	RP11-767N6.2	0.05	0.01	enet	13	0.02	1.6e-02	-5.1	-5.2	2.0e-07	0.00	0.56	0.20	FALSE
15	GTEx	Stomach	RP11-767N6.7	0.08	0.03	enet	16	0.05	1.3e-03	4.5	7.1	1.4e-12	0.03	0.10	0.75	TRUE
16	GTEx	Testis	GPBP1L1	0.07	0.06	enet	7	0.03	1.7e-02	4.0	5.5	4.9e-08	0.03	0.24	0.44	FALSE
17	GTEx	Testis	IPP	0.05	0.06	enet	8	0.03	1.4e-02	-5.1	-5.4	8.5e-08	-0.03	0.26	0.24	FALSE
18	GTEx	Thyroid	MAST2	0.06	0.05	lasso	4	0.04	4.9e-04	-5.4	5.5	3.3e-08	0.01	0.61	0.25	FALSE
19	GTEx	Thyroid	GPBP1L1	0.05	0.06	enet	6	0.07	7.9e-06	-5.3	5.5	3.1e-08	0.04	0.80	0.17	FALSE
20	GTEx	Whole Blood	MAST2	0.03	0.02	lasso	3	0.02	2.9e-03	-5.2	5.5	4.3e-08	0.04	0.38	0.23	FALSE
21	GTEx	Whole Blood	RP1-18D14.7	0.15	0.13	enet	17	0.13	7.7e-12	8.3	-6.2	5.5e-10	0.03	0.01	0.99	FALSE
22	METSIM	Adipose	AGBL4	0.02	0.02	lasso	5	0.02	1.3e-03	7.5	-7.6	2.2e-14	-0.86	0.16	0.82	TRUE
23	METSIM	Adipose	CCDC17	0.03	0.02	blup	287	0.01	5.6e-03	4.4	5.3	1.5e-07	0.04	0.42	0.02	FALSE
24	ROSMAP	Brain Pre-frontal Cortex	IPP	0.08	0.15	lasso	9	0.14	5.0e-18	-5.3	5.3	1.1e-07	0.04	0.81	0.19	FALSE
25	ROSMAP	Brain Pre-frontal Cortex	RPS15AP10	0.03	0.05	blup	283	0.04	8.0e-06	-5.2	-5.3	1.2e-07	-0.03	0.78	0.21	FALSE
26	YFS	Blood	CCDC17	0.04	0.02	lasso	8	0.02	6.8e-08	-5.1	5.5	4.0e-08	0.04	0.85	0.15	FALSE
27	YFS	Blood	IPP	0.10	0.11	lasso	15	0.12	4.6e-36	-5.3	5.2	1.6e-07	0.04	0.72	0.28	FALSE
28	YFS	Blood	TAL1	0.03	0.02	bslmm	402	0.02	2.6e-06	8.3	-7.9	2.9e-15	0.04	0.01	0.99	TRUE
29	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	TAL1	0.03	0.02	blup	75	0.02	9.2e-03	6.8	6.5	7.0e-11	-0.02	0.02	0.81	FALSE
30	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GPBP1L1	0.03	0.04	lasso	1	0.03	8.0e-05	-5.2	5.2	2.3e-07	0.04	0.04	0.94	FALSE
31	The Cancer Genome Atlas	Prostate Adenocarcinoma	GPBP1L1	0.04	0.04	blup	50	0.04	2.9e-05	-5.0	5.3	8.7e-08	0.05	0.04	0.94	FALSE
32	The Cancer Genome Atlas	Stomach Adenocarcinoma	IPP	0.04	0.04	blup	47	0.04	1.4e-03	-5.1	5.5	4.5e-08	0.05	0.03	0.79	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	GPBP1L1	0.11	0.06	lasso	3	0.06	1.6e-06	-5.0	5.2	1.9e-07	0.04	0.06	0.94	FALSE