[Hub]/) : Traits : BMI : ← →

chr7:100,110,324-101,482,413

Best TWAS P=6.37e-10 · Best GWAS P=3.07e-09 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	AP1S1	0.10	0.10	lasso	2	0.12	6.6e-10	4.9	5.7	1.0e-08	0.90	0.01	0.99	FALSE
2	GTEx	Adrenal Gland	AP1S1	0.62	0.40	lasso	9	0.46	1.6e-18	4.9	5.6	2.1e-08	0.80	0.33	0.67	FALSE
3	GTEx	Artery Aorta	AP1S1	0.23	0.13	lasso	4	0.10	6.5e-06	4.9	5.2	1.8e-07	0.77	0.07	0.92	FALSE
4	GTEx	Brain Cerebellar Hemisphere	AP1S1	0.30	0.32	lasso	2	0.30	1.7e-08	5.8	5.8	4.8e-09	1.00	0.00	1.00	FALSE
5	GTEx	Brain Cerebellum	AP1S1	0.39	0.22	enet	16	0.24	1.4e-07	5.9	5.9	3.6e-09	0.91	0.00	1.00	FALSE
6	GTEx	Brain Nucleus accumbens basal ganglia	AP1S1	0.40	0.06	enet	5	0.04	3.0e-02	5.9	5.1	2.8e-07	0.93	0.01	0.93	FALSE
7	GTEx	Breast Mammary Tissue	AP1S1	0.18	0.14	lasso	4	0.12	1.5e-06	5.9	6.2	6.4e-10	0.96	0.00	1.00	TRUE
8	GTEx	Esophagus Mucosa	AP1S1	0.16	0.08	lasso	3	0.08	2.6e-06	5.9	5.9	4.5e-09	0.92	0.01	0.99	FALSE
9	GTEx	Nerve Tibial	AP1S1	0.34	0.25	enet	19	0.24	8.9e-17	5.9	5.4	6.3e-08	0.94	0.00	1.00	FALSE
10	GTEx	Pituitary	AP1S1	0.41	0.27	lasso	5	0.27	2.2e-07	4.9	5.8	5.2e-09	0.91	0.00	1.00	FALSE
11	GTEx	Skin Not Sun Exposed Suprapubic	AP1S1	0.34	0.31	lasso	4	0.29	4.2e-16	5.8	5.9	4.4e-09	1.00	0.00	1.00	FALSE
12	GTEx	Skin Sun Exposed Lower leg	AP1S1	0.45	0.36	lasso	6	0.39	8.6e-34	5.9	6.1	1.3e-09	0.96	0.00	1.00	FALSE
13	GTEx	Testis	AP1S1	0.30	0.20	lasso	2	0.25	1.3e-11	5.9	5.9	3.6e-09	0.94	0.00	1.00	FALSE
14	GTEx	Thyroid	AP1S1	0.21	0.20	lasso	3	0.20	4.5e-15	5.9	6.0	1.7e-09	1.00	0.00	1.00	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	AP1S1	0.28	0.27	bslmm	377	0.27	1.2e-34	5.9	6.0	2.5e-09	0.98	0.00	1.00	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	AP1S1	0.04	0.04	lasso	1	0.04	3.3e-08	5.5	5.5	4.5e-08	0.85	0.02	0.98	FALSE
17	The Cancer Genome Atlas	Colon Adenocarcinoma	AP1S1	0.10	0.05	blup	52	0.05	1.1e-03	4.9	5.7	1.6e-08	0.64	0.14	0.66	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	AP1S1	0.16	0.05	lasso	3	0.09	7.7e-10	4.9	5.8	6.9e-09	0.82	0.18	0.82	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	C7orf52	0.03	0.02	blup	53	0.02	2.7e-03	4.7	5.2	2.2e-07	0.90	0.01	0.96	FALSE
20	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C7orf52	0.23	0.10	blup	54	0.12	7.0e-06	5.8	-5.2	2.2e-07	-0.86	0.00	0.99	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	AP1S1	0.07	0.05	lasso	6	0.06	3.6e-07	5.8	6.0	2.5e-09	0.92	0.00	1.00	FALSE