Best TWAS P=7.88e-08 · Best GWAS P=2.79e-08 conditioned to 0.00147
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Atrial Appendage | MAP2K5 | 0.16 | 0.08 | lasso | 5 | 0.16 | 1.3e-07 | -4.6 | 5.4 | 7.9e-08 | -0.53 | 0.11 | 0.88 | TRUE |
| 2 | GTEx | Muscle Skeletal | MAP2K5 | 0.08 | 0.03 | lasso | 6 | 0.05 | 1.9e-05 | 4.5 | 5.1 | 3.1e-07 | -0.48 | 0.08 | 0.91 | FALSE |