TWAS
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About
Usage
Models
Genes
Traits
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Traits
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Cardiovascular Disease
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chr15:80,293,439-81,737,095
Best TWAS P=2.53e-14 · Best GWAS P=3.8e-16 conditioned to 0.000757
80.4M
80.6M
80.8M
81M
81.2M
81.4M
81.6M
81.8M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
FAM108C1
0.07
0.02
lasso
2
0.02
1.7e-03
-6.1
-7.6
2.5e-14
-0.81
0.04
0.56
TRUE
2
The Cancer Genome Atlas
Lung Adenocarcinoma
FAM108C1
0.05
0.04
lasso
3
0.04
5.6e-06
7.7
-7.5
6.1e-14
-0.83
0.08
0.92
FALSE
1
NTR
Blood
FAM108C1
0.02
0.01
bslmm
542
0.01
6.1e-03
-3.9
5.1
3.0e-07
0.53
0.05
0.55
FALSE