Best TWAS P=2.53e-14 · Best GWAS P=3.8e-16 conditioned to 0.000757
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | FAM108C1 | 0.02 | 0.01 | bslmm | 542 | 0.01 | 6.1e-03 | -3.9 | 5.1 | 3.0e-07 | 0.53 | 0.05 | 0.55 | FALSE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | FAM108C1 | 0.05 | 0.04 | lasso | 3 | 0.04 | 5.6e-06 | 7.7 | -7.5 | 6.1e-14 | -0.83 | 0.08 | 0.92 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FAM108C1 | 0.07 | 0.02 | lasso | 2 | 0.02 | 1.7e-03 | -6.1 | -7.6 | 2.5e-14 | -0.81 | 0.04 | 0.56 | TRUE |