[Hub]/) : Traits : Cardiovascular Disease :

chr15:90,712,555-92,135,418

Best TWAS P=2.89e-36 · Best GWAS P=5.28e-30 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FURIN 0.12 0.14 lasso 2 0.13 1.2e-15 -7.3 7.3 2.6e-13 0.62 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum FES 0.21 0.09 lasso 5 0.05 1.3e-03 11.4 -11.2 3.1e-29 -0.99 0.00 1.00 FALSE
3 GTEx Artery Tibial FES 0.16 0.04 lasso 5 0.05 4.8e-05 10.1 -11.7 1.3e-31 -0.89 0.00 1.00 FALSE
4 GTEx Cells Transformed fibroblasts FES 0.28 0.17 enet 21 0.20 2.8e-15 11.4 -12.0 2.8e-33 -0.92 0.00 1.00 FALSE
5 GTEx Lung FES 0.24 0.07 lasso 6 0.05 5.1e-05 10.1 -12.0 4.6e-33 -0.90 0.00 1.00 FALSE
6 GTEx Skin Sun Exposed Lower leg FES 0.09 0.04 lasso 5 0.04 1.4e-04 11.4 -10.1 3.6e-24 -0.91 0.00 0.99 FALSE
7 GTEx Thyroid FES 0.33 0.19 lasso 6 0.18 4.3e-14 10.7 -10.9 1.9e-27 -0.95 0.01 0.99 FALSE
8 METSIM Adipose FES 0.08 0.06 lasso 3 0.05 6.8e-08 10.5 -10.4 2.2e-25 -0.88 0.14 0.86 FALSE
9 YFS Blood FES 0.31 0.11 enet 77 0.22 1.2e-68 11.4 -10.2 1.7e-24 -0.61 0.00 1.00 FALSE
10 YFS Blood FURIN 0.11 0.03 enet 37 0.06 8.3e-19 -7.3 -7.0 3.2e-12 -0.48 0.68 0.32 FALSE
11 The Cancer Genome Atlas Bladder Urothelial Carcinoma FES 0.06 0.05 blup 46 0.06 1.9e-05 10.8 -10.0 1.7e-23 -0.74 0.02 0.96 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma FES 0.06 0.05 blup 46 0.07 7.4e-14 11.4 -11.9 7.4e-33 -0.88 0.00 1.00 FALSE
13 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FES 0.06 0.02 blup 46 0.02 2.4e-02 11.4 -10.7 1.2e-26 -0.81 0.00 0.90 FALSE
14 The Cancer Genome Atlas Colon Adenocarcinoma FES 0.08 0.07 blup 46 0.06 3.4e-04 10.2 -10.9 9.5e-28 -0.84 0.05 0.86 FALSE
15 The Cancer Genome Atlas Glioblastoma Multiforme FES 0.12 0.06 enet 6 0.06 5.7e-03 10.9 -11.1 1.2e-28 -0.80 0.01 0.80 FALSE
16 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FES 0.06 0.03 blup 46 0.05 5.6e-06 10.9 -9.8 1.7e-22 -0.78 0.01 0.99 FALSE
17 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FES 0.10 0.07 enet 5 0.05 2.8e-06 10.8 -10.4 2.0e-25 -0.70 0.33 0.67 FALSE
18 The Cancer Genome Atlas Lung Adenocarcinoma FES 0.05 0.04 lasso 2 0.04 2.2e-05 11.4 -12.0 4.1e-33 -0.95 0.00 1.00 FALSE
19 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FES 0.08 0.07 enet 7 0.08 4.2e-09 11.4 -11.7 8.1e-32 -0.93 0.00 1.00 FALSE
20 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma FES 0.13 0.16 lasso 2 0.14 6.1e-10 11.4 -11.3 8.5e-30 -0.99 0.00 1.00 FALSE
21 The Cancer Genome Atlas Prostate Adenocarcinoma FES 0.12 0.09 lasso 5 0.08 4.1e-09 11.4 -12.6 2.9e-36 -0.95 0.00 1.00 TRUE
22 The Cancer Genome Atlas Stomach Adenocarcinoma FES 0.04 0.01 blup 46 0.02 1.7e-02 10.8 -10.6 2.0e-26 -0.75 0.01 0.55 FALSE
23 The Cancer Genome Atlas Testicular Germ Cell Tumors FES 0.32 0.26 lasso 2 0.25 2.0e-09 11.3 -11.3 9.7e-30 -0.96 0.00 1.00 FALSE
24 The Cancer Genome Atlas Thyroid Carcinoma FES 0.30 0.30 lasso 7 0.32 1.3e-31 11.3 -12.3 9.5e-35 -0.95 0.00 1.00 FALSE