Best TWAS P=5.37e-09 · Best GWAS P=4.92e-10 conditioned to 5.09e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | BZRAP1 | 0.30 | 0.19 | lasso | 11 | 0.19 | 1.2e-05 | 4.6 | 5.3 | 8.7e-08 | 0.42 | 0.19 | 0.67 | FALSE |
| 2 | GTEx | Muscle Skeletal | SKA2 | 0.04 | 0.02 | enet | 12 | 0.04 | 1.0e-04 | 6.2 | -5.2 | 1.7e-07 | -0.81 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Pituitary | BZRAP1-AS1 | 0.16 | 0.04 | enet | 8 | 0.02 | 8.0e-02 | 5.9 | 5.8 | 5.4e-09 | 0.44 | 0.04 | 0.54 | TRUE |
| 4 | METSIM | Adipose | TEX14 | 0.05 | 0.05 | lasso | 2 | 0.04 | 4.1e-07 | 5.8 | 5.8 | 5.9e-09 | 0.39 | 0.02 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TEX14 | 0.10 | 0.08 | enet | 8 | 0.10 | 2.1e-11 | 5.4 | 5.1 | 2.8e-07 | 0.38 | 0.04 | 0.96 | FALSE |
| 6 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | TRIM37 | 0.19 | 0.00 | enet | 11 | 0.06 | 5.0e-03 | 4.9 | 5.2 | 2.6e-07 | 0.37 | 0.01 | 0.29 | FALSE |