Best TWAS P=3.27e-09 · Best GWAS P=4.32e-09 conditioned to 0.0244
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | RP11-332H18.4 | 0.22 | 0.07 | lasso | 7 | 0.05 | 9.0e-04 | -5.7 | -5.9 | 3.3e-09 | 0.73 | 0.01 | 0.98 | TRUE |
| 2 | GTEx | Artery Tibial | RP11-332H18.4 | 0.18 | 0.15 | lasso | 1 | 0.14 | 4.5e-11 | -5.7 | -5.7 | 1.3e-08 | 0.80 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | RP11-332H18.4 | 0.19 | 0.16 | lasso | 4 | 0.14 | 1.7e-10 | -5.7 | -5.8 | 6.2e-09 | 0.79 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Esophagus Mucosa | RP11-332H18.4 | 0.19 | 0.09 | lasso | 4 | 0.04 | 9.6e-04 | -5.7 | -5.9 | 4.1e-09 | 0.81 | 0.01 | 0.99 | FALSE |
| 5 | GTEx | Lung | RP11-332H18.4 | 0.10 | 0.04 | enet | 3 | 0.07 | 6.8e-06 | -5.7 | -5.9 | 4.3e-09 | 0.76 | 0.01 | 0.99 | FALSE |
| 6 | GTEx | Testis | TBX2 | 0.20 | 0.18 | lasso | 3 | 0.15 | 4.8e-07 | -5.7 | -5.8 | 8.0e-09 | 0.82 | 0.01 | 0.99 | FALSE |
| 7 | GTEx | Testis | RP11-332H18.4 | 0.19 | 0.19 | lasso | 2 | 0.16 | 1.6e-07 | -5.6 | -5.7 | 9.9e-09 | 0.83 | 0.01 | 0.99 | FALSE |
| 8 | GTEx | Thyroid | TBX2 | 0.10 | 0.09 | lasso | 2 | 0.06 | 1.7e-05 | -5.7 | -5.7 | 1.3e-08 | 0.80 | 0.01 | 0.99 | FALSE |
| 9 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | C17orf82 | 0.03 | 0.02 | blup | 42 | 0.00 | 1.3e-01 | -5.2 | 5.8 | 6.8e-09 | -0.70 | 0.04 | 0.74 | FALSE |