Hub : Genes

TRIM37

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0480 0.0190 8.1e-06 0.024 0.038 0.034 0.037 0.032 5.4e-04 1.9e-05 4.6e-05 2.4e-05 8.6e-05
2 GTEx Adipose Subcutaneous 0.1760 0.0480 2.2e-16 0.223 NA 0.244 NA 0.236 3.7e-18 NA 6.9e-20 NA 3.4e-19
3 GTEx Adipose Visceral Omentum 0.1940 0.0590 6.5e-11 0.247 NA 0.240 NA 0.250 4.3e-13 NA 9.6e-13 NA 3.1e-13
4 GTEx Adrenal Gland 0.0990 0.0454 1.8e-03 0.017 NA 0.014 NA 0.001 8.1e-02 NA 9.9e-02 NA 2.9e-01
5 GTEx Artery Aorta 0.0640 0.0280 4.4e-04 0.034 NA 0.042 NA 0.036 5.5e-03 NA 2.4e-03 NA 4.4e-03
6 GTEx Artery Tibial 0.0965 0.0334 6.5e-08 0.154 NA 0.139 NA 0.152 4.5e-12 NA 5.0e-11 NA 5.8e-12
7 GTEx Breast Mammary Tissue 0.2570 0.0810 2.9e-08 0.167 NA 0.172 NA 0.148 6.4e-09 NA 3.7e-09 NA 5.2e-08
8 GTEx Breast Mammary Tissue (Female) 0.1762 0.0833 1.7e-03 0.082 NA 0.009 NA 0.020 1.9e-03 NA 1.6e-01 NA 8.2e-02
9 GTEx Colon Transverse 0.1430 0.0480 5.2e-08 0.152 NA 0.129 NA 0.171 1.0e-07 NA 1.0e-06 NA 1.5e-08
10 GTEx Esophagus Gastroesophageal Junction 0.1470 0.0600 5.7e-05 0.064 NA 0.093 NA 0.096 2.5e-03 NA 3.0e-04 NA 2.4e-04
11 GTEx Esophagus Mucosa 0.1850 0.0620 3.9e-08 0.113 NA 0.112 NA 0.103 5.9e-08 NA 6.7e-08 NA 2.3e-07
12 GTEx Esophagus Muscularis 0.1080 0.0400 1.2e-06 0.052 NA 0.076 NA 0.093 4.1e-04 NA 2.3e-05 NA 2.7e-06
13 GTEx Heart Atrial Appendage 0.1310 0.0550 6.0e-04 0.044 NA 0.048 NA 0.057 4.6e-03 NA 3.2e-03 NA 1.4e-03
14 GTEx Lung 0.0474 0.0202 2.7e-04 0.040 NA 0.054 NA 0.048 4.5e-04 NA 5.3e-05 NA 1.4e-04
15 GTEx Muscle Skeletal 0.1396 0.0407 4.7e-14 0.093 NA 0.154 NA 0.145 1.9e-09 NA 6.7e-15 NA 4.3e-14
16 GTEx Nerve Tibial 0.1785 0.0516 6.5e-14 0.157 NA 0.199 NA 0.227 3.2e-11 NA 4.6e-14 NA 4.3e-16
17 GTEx Pancreas 0.0840 0.0400 3.0e-03 0.045 NA 0.009 NA 0.025 5.3e-03 NA 1.3e-01 NA 3.2e-02
18 GTEx Skin Not Sun Exposed Suprapubic 0.0700 0.0310 3.5e-04 0.086 NA 0.060 NA 0.059 1.8e-05 NA 3.2e-04 NA 3.7e-04
19 GTEx Small Intestine Terminal Ileum 0.1900 0.0780 3.8e-04 0.141 NA 0.124 NA 0.090 5.0e-04 NA 1.1e-03 NA 5.0e-03
20 GTEx Spleen 0.1320 0.0650 3.2e-03 0.077 NA 0.176 NA 0.115 5.2e-03 NA 2.8e-05 NA 7.2e-04
21 GTEx Stomach 0.1320 0.0640 1.0e-04 0.084 NA 0.090 NA 0.082 7.5e-05 NA 4.5e-05 NA 9.5e-05
22 GTEx Testis 0.1680 0.0550 1.8e-07 0.226 NA 0.183 NA 0.192 2.1e-10 NA 1.5e-08 NA 6.3e-09
23 GTEx Thyroid 0.0410 0.0200 1.2e-03 0.039 NA 0.059 NA 0.058 5.4e-04 NA 2.4e-05 NA 3.0e-05
24 GTEx Whole Blood 0.1240 0.0380 4.2e-14 0.180 NA 0.181 NA 0.176 2.4e-16 NA 1.8e-16 NA 5.3e-16
25 METSIM Adipose 0.1106 0.0326 2.1e-15 0.114 0.118 0.104 0.119 0.104 1.1e-16 2.9e-17 2.5e-15 2.0e-17 2.5e-15
26 NTR Blood 0.0202 0.0074 2.8e-09 0.032 0.027 0.031 0.027 0.033 1.1e-10 4.5e-09 2.5e-10 4.2e-09 6.4e-11
27 TCGA Cervical Squamous Cell Carcinoma 0.0970 0.0610 6.8e-04 0.052 0.069 0.054 NA 0.047 1.4e-03 2.7e-04 1.2e-03 NA 2.4e-03
28 TCGA Head and Neck Squamous Cell Carcinoma 0.0306 0.0216 3.1e-03 0.028 0.023 0.023 NA 0.023 3.7e-04 1.2e-03 1.2e-03 NA 1.1e-03
29 TCGA Kidney Renal Clear Cell Carcinoma 0.1187 0.0501 2.9e-10 0.048 0.093 0.083 NA 0.071 4.0e-06 1.3e-10 1.3e-09 NA 1.9e-08
30 TCGA Prostate Adenocarcinoma 0.0512 0.0297 9.0e-06 0.031 0.053 0.047 NA 0.043 3.1e-04 3.1e-06 1.1e-05 NA 2.6e-05
31 TCGA Testicular Germ Cell Tumors 0.1870 0.1090 9.2e-03 -0.004 0.031 0.056 NA 0.020 4.7e-01 2.8e-02 5.0e-03 NA 6.3e-02
32 TCGA Thyroid Carcinoma 0.0500 0.0310 1.4e-04 0.027 0.046 0.029 NA 0.037 1.0e-03 2.7e-05 6.6e-04 NA 1.6e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32
Bipolar Disorder (2018) 0.5 0.8 2.9 1.4 -0.4 -0.3 -0.4 -1.0 -1.2 -0.6 -0.4 -1.0 -0.5 -0.9 -1.0 -1.4 -0.4 -1.2 -0.7 -0.4 -1.0 -1.7 -0.1 -0.6 -0.6 -0.7 -0.4 -0.1 -0.4 -0.8 -1.2 -0.0 -0.4 -1.7 -1.1
Bipolar Disorder or Schizophrenia 1.3 3.1 14.1 3.8 -0.9 -0.6 -1.7 -1.9 -2.8 -0.8 -0.5 -1.8 -1.6 -2.1 -1.9 -2.0 -0.8 -2.1 -1.7 -0.5 -2.1 -2.4 -0.8 -1.5 -1.0 -2.0 -1.1 -0.0 -0.6 -2.1 -2.5 -1.6 -1.4 -1.6 -2.0
Depressed Affect (Nagel 2018) 0.9 1.8 5.0 0.8 -1.6 -1.3 -0.7 -1.5 -1.4 -2.2 -1.0 -1.3 -1.2 -1.4 -1.5 -0.8 -1.3 -1.6 -1.4 -0.9 -1.5 -0.6 -1.5 -1.7 0.7 -1.5 -1.4 -1.4 -1.2 -1.6 -1.4 -1.6 -1.5 -0.8 -1.4
Depression (Nagel 2018) 0.3 0.5 1.7 0.8 0.6 1.0 0.5 0.6 -0.2 -0.2 0.9 0.8 0.3 -0.5 0.6 0.2 0.8 0.8 0.6 1.3 0.4 0.1 0.5 0.6 -1.2 0.7 0.7 0.9 1.3 0.4 0.1 0.2 0.5 0.8 0.4
Intelligence (Savage-Jansen 2018) 11.2 34.3 55.6 -0.9 7.1 6.9 4.0 6.6 4.4 6.3 7.2 6.8 6.0 4.2 6.3 3.7 6.6 5.7 6.3 7.5 4.7 1.9 6.8 5.9 -6.7 6.4 7.2 6.8 7.3 4.9 4.3 6.2 6.3 0.8 6.2
Neuroticism (Nagel 2018) 1.1 2.6 5.3 2.2 -1.6 -1.0 -1.7 -1.8 -2.3 -2.2 -0.4 -1.6 -1.5 -1.3 -1.9 -0.8 -1.3 -1.7 -1.6 -0.5 -2.1 -1.7 -1.6 -2.1 -0.3 -2.2 -1.0 -1.2 -1.1 -2.2 -2.3 -1.6 -1.8 -1.2 -1.3
Schizophrenia (2018) 1.2 2.6 13.7 3.7 -0.8 -0.5 -1.9 -1.7 -2.7 -0.5 -0.4 -1.5 -1.7 -2.0 -1.6 -1.4 -0.8 -1.8 -1.6 -0.4 -1.9 -1.7 -0.9 -1.5 -0.8 -1.9 -1.1 0.1 -0.4 -1.9 -2.3 -1.9 -1.4 -0.1 -1.6
Schizophrenia vs Biploar Disorder 0.4 0.6 2.6 1.6 -0.5 -0.4 -0.5 -0.7 -1.4 0.4 -0.2 -0.6 -0.7 -0.8 -0.3 -1.2 -0.4 -0.5 -0.9 -0.1 -1.1 -1.1 0.4 -1.0 -0.2 -0.7 -0.5 0.3 0.1 -0.8 -1.0 -1.1 -0.8 0.9 -0.4
Worry (Nagel 2018) 3.5 7.4 12.6 2.9 -2.6 -2.2 -3.1 -3.2 -3.5 -3.0 -1.5 -2.8 -2.9 -1.8 -3.1 -1.9 -2.6 -3.0 -3.1 -1.7 -3.4 -2.6 -2.5 -3.1 0.5 -3.5 -2.2 -2.3 -2.1 -3.4 -3.6 -2.7 -3.1 -2.1 -2.4
Alzheimer’s Disease (in mother) 0.3 0.4 2.0 -1.4 0.1 0.0 0.3 0.2 1.3 0.7 -0.1 0.1 0.2 1.1 0.1 0.9 0.1 0.1 0.6 -0.1 0.4 0.4 0.1 0.9 0.8 0.2 0.3 0.0 0.0 0.5 1.2 0.4 0.2 0.2 0.8
Alzheimer’s Disease (in father) 0.0 0.0 0.5 -0.2 0.1 0.0 -0.2 0.1 0.0 0.2 -0.1 0.1 0.1 -0.6 -0.1 0.3 -0.1 -0.3 0.0 0.1 0.1 0.7 0.5 0.1 -0.0 0.2 -0.1 0.2 0.0 -0.1 -0.1 -0.0 0.0 -0.1 -0.0
Alzheimer’s Disease (including proxy) 0.6 0.9 3.3 -1.2 -1.1 -1.3 -0.5 -1.1 0.3 -0.2 -1.4 -1.3 -0.9 -0.5 -1.2 0.2 -1.3 -1.2 -0.8 -1.4 -0.6 -0.0 -0.9 -0.3 1.8 -1.0 -1.1 -0.9 -1.4 -0.6 0.1 -0.6 -1.0 -0.5 -0.4
Crohns Disease (2017) 0.5 1.1 4.4 1.3 -0.9 -0.5 -1.6 -1.2 -1.4 -0.7 -0.3 -1.2 -1.0 -0.7 -1.1 -1.8 -0.8 -0.8 -1.1 -0.7 -1.4 -0.8 -0.2 -1.0 -0.3 -1.1 -0.7 -0.5 -0.4 -1.5 -1.4 -0.4 -0.8 -2.1 -0.9
Irritable Bowel Disease (IBD) 1.0 2.3 5.2 1.6 -1.7 -1.0 -2.1 -1.8 -2.2 -0.6 -0.7 -1.6 -1.6 -1.3 -1.6 -2.0 -1.4 -1.5 -1.8 -1.0 -2.2 -1.0 -0.8 -1.1 0.2 -1.8 -1.3 -0.5 -0.9 -2.0 -2.2 -0.5 -1.4 -2.3 -1.3
Ulcerative Colitis (UC) 0.5 0.9 2.2 0.9 -1.4 -0.7 -1.3 -1.1 -1.5 -0.1 -0.4 -0.9 -1.0 -1.0 -1.0 -1.0 -0.9 -0.9 -1.1 -0.5 -1.4 0.1 -0.6 -0.2 0.2 -1.2 -0.9 -0.1 -0.7 -1.3 -1.4 -0.2 -0.8 -1.4 -0.7
Major Depression (MDD) 1.0 1.2 3.2 0.3 -1.3 -1.3 -0.6 -1.2 -0.5 -1.0 -1.4 -1.3 -0.8 -1.1 -1.4 -0.2 -1.2 -1.4 -1.0 -1.4 -0.2 -0.3 -1.0 -1.2 0.9 -1.2 -1.7 -1.3 -1.3 -0.9 -0.6 -1.8 -1.4 0.9 -0.3
Reaction Time 6.9 13.2 17.8 2.3 -4.0 -3.4 -3.1 -4.2 -4.1 -4.0 -3.1 -3.9 -4.0 -3.9 -4.0 -3.2 -3.6 -3.4 -4.0 -3.2 -4.2 -3.6 -3.0 -3.9 2.5 -4.2 -3.7 -3.2 -3.3 -4.1 -4.0 -3.8 -3.9 -2.5 -4.2
Verbal and Numeric Reasoning (VNR) 7.9 19.0 33.9 -0.1 5.1 5.4 2.6 4.6 2.9 5.3 5.6 5.0 4.2 2.8 4.5 2.6 4.9 3.8 4.5 5.8 3.0 1.6 5.4 4.5 -5.4 4.3 5.3 5.5 5.5 3.5 2.9 5.0 4.7 -0.1 4.6
Breast Cancer 1.9 4.5 9.2 0.6 2.4 2.7 1.6 2.4 1.3 2.1 2.9 2.7 1.9 0.5 2.5 0.2 2.4 2.2 2.3 3.0 1.5 1.8 2.9 1.6 -2.7 2.1 2.5 2.1 2.7 1.4 1.2 2.2 2.3 -1.1 2.0
Ovarian Cancer 0.3 0.3 0.8 0.1 0.8 0.6 0.2 0.6 0.6 0.1 0.7 0.8 0.6 0.8 0.8 0.2 0.6 0.3 0.7 0.6 0.6 -0.5 -0.1 0.5 -0.5 0.6 0.4 0.9 0.9 0.6 0.6 0.7 0.7 -0.5 0.3
Prostate Cancer 1.4 2.0 6.6 -2.4 0.5 0.2 2.4 1.2 2.2 0.3 -0.2 0.8 1.3 1.6 1.2 1.1 0.9 1.6 1.4 -0.3 2.4 1.7 0.4 0.5 0.9 1.6 0.4 -0.7 0.0 2.1 2.3 0.7 1.3 2.6 1.1
Age at First Birth 1.3 1.8 5.3 0.1 1.9 1.9 0.2 1.5 0.2 1.3 1.8 1.8 0.6 0.5 1.2 1.6 1.3 1.3 1.2 2.3 0.1 0.8 1.7 0.7 -1.7 1.3 1.8 1.8 2.3 0.6 0.0 1.5 1.3 0.0 1.5
Bipolar Disorder (2011) 2.1 2.0 3.8 1.8 -1.1 -1.4 -1.3 -1.7 -1.3 -1.3 -1.5 -1.8 -1.1 -1.7 -1.9 -1.1 -1.0 -1.9 -1.3 -1.6 -1.2 -1.8 -1.3 -1.4 0.4 -1.9 -1.5 -1.0 -1.7 -1.2 -1.2 -0.9 -1.2 -1.4 -1.5
Body Mass Index (BMI) (2010) 0.2 0.2 1.1 -0.8 0.4 0.3 0.2 0.4 0.4 0.1 0.3 0.3 0.1 0.5 0.4 0.6 0.3 0.7 0.4 0.3 0.5 0.5 0.4 0.1 0.2 0.3 0.3 -0.0 0.6 0.5 0.5 0.1 0.3 1.1 0.7
Coronary Artery Disease (CAD) 0.1 0.1 1.4 0.0 0.0 -0.0 1.1 0.0 0.1 -0.2 0.1 -0.1 0.4 -0.5 0.5 -1.2 -0.0 0.2 -0.0 0.2 0.5 0.2 0.5 0.2 -0.3 0.2 -0.1 0.0 0.2 0.2 0.2 0.1 -0.0 0.0 0.4
Crohns Disease (2012) 0.4 0.6 3.6 1.6 -0.1 0.4 -1.4 -0.4 -1.2 0.1 0.4 -0.4 -0.7 -0.1 -0.6 -1.0 -0.1 -0.4 -0.4 0.3 -1.0 -1.2 0.0 -0.2 -1.3 -0.4 0.2 0.4 0.5 -1.1 -1.3 0.2 -0.2 -1.9 -0.2
Mean Putamen Volume 0.2 0.3 4.3 -0.3 -0.0 -0.0 -0.3 0.4 0.6 -0.6 -0.4 0.5 0.0 0.0 -0.1 0.9 -0.2 -0.1 0.2 0.2 0.1 0.6 0.2 -0.3 -0.1 0.3 0.0 -0.8 0.0 -0.6 -0.0 -0.2 -0.2 -2.1 -0.3
Fasting Glucose 1.3 1.5 4.9 0.0 1.1 1.2 1.6 1.3 0.5 1.3 1.3 1.2 1.3 0.3 1.8 -0.3 1.2 1.4 0.9 1.4 1.1 0.6 1.8 0.9 -0.6 1.6 1.0 1.5 1.4 1.3 0.9 0.9 1.2 2.2 1.1
HbA1C 0.3 0.3 1.8 1.4 0.2 0.4 -1.2 0.2 -0.7 0.0 0.5 0.4 -0.3 0.7 0.1 0.0 0.2 0.2 -0.2 0.4 -0.1 -0.8 -0.3 -0.6 -1.1 0.0 0.3 -0.3 0.6 -0.6 -0.7 -0.8 -0.3 -0.2 0.3
HDL Cholesterol 0.1 0.2 0.7 -0.6 -0.3 -0.4 0.0 -0.4 0.1 -0.8 -0.3 -0.5 -0.6 -0.5 -0.4 -0.3 -0.5 -0.3 -0.3 -0.5 -0.5 0.0 -0.1 -0.1 0.8 -0.3 -0.5 -0.2 -0.6 -0.1 -0.0 0.3 -0.1 -0.7 -0.7
LDL Cholesterol 0.1 0.2 1.7 1.3 0.4 0.5 -0.2 0.0 -0.3 0.5 0.8 0.1 0.2 -0.5 0.1 -0.6 0.3 0.5 0.1 0.4 0.0 -0.5 0.4 -0.3 -0.7 0.1 0.5 0.3 0.3 -0.2 -0.2 0.1 0.1 -0.3 0.1
Lupus 0.1 0.2 1.0 -1.0 0.1 -0.2 -0.3 -0.1 0.4 -0.9 -0.2 -0.2 0.4 0.4 -0.4 1.0 -0.1 0.1 0.1 -0.2 0.2 0.6 -0.5 -0.1 0.3 -0.3 -0.1 -0.4 -0.1 0.0 0.4 -0.5 -0.2 0.5 0.4
Neuroticism (2016) 1.5 2.2 5.9 2.4 -1.1 -0.8 -1.3 -1.4 -2.3 -1.4 -0.7 -1.0 -1.8 -2.4 -1.3 -2.0 -1.0 -1.0 -1.7 -0.0 -2.1 -0.7 -0.6 -1.5 -0.2 -1.7 -1.0 -0.9 -0.6 -2.0 -2.1 -1.3 -1.5 -1.4 -1.5
Primary Biliary Cirrhosis 1.3 1.9 4.7 -0.4 -1.9 -1.4 -0.1 -2.0 -1.1 -1.3 -1.3 -2.1 -1.2 -1.5 -1.8 -1.0 -1.5 -1.7 -1.3 -1.8 -1.3 -0.2 -1.7 -0.6 1.3 -2.2 -1.6 -1.0 -1.9 -0.9 -1.0 -0.8 -1.2 -0.2 -1.2
Rheumatoid Arthritis 1.6 2.2 9.0 -3.0 1.5 1.0 0.3 1.2 2.3 0.8 0.7 1.0 1.3 2.8 1.1 1.7 1.1 1.0 1.7 0.0 1.6 1.2 1.0 2.2 -0.0 1.1 1.0 1.0 0.7 1.9 2.3 1.2 1.3 1.6 1.8
Schizophrenia (2014) 1.8 4.0 17.6 4.2 -1.2 -1.0 -2.0 -2.2 -3.3 -0.8 -0.8 -2.0 -2.1 -3.0 -2.0 -2.4 -1.1 -2.0 -2.1 -0.4 -2.7 -2.2 -0.5 -2.0 -0.9 -2.2 -1.3 -0.1 -0.5 -2.4 -2.7 -2.1 -1.9 -0.9 -2.0
Triglycerides 1.1 1.8 3.8 -0.1 1.2 1.6 0.4 1.5 1.0 1.6 1.7 1.7 1.2 1.1 1.4 1.6 1.4 1.4 1.4 1.9 0.9 1.0 1.7 1.3 -1.5 1.4 1.5 1.4 1.6 0.8 1.0 1.0 1.1 0.6 1.8
Type 2 Diabetes (T2D) (2012) 6.3 7.2 10.9 -0.3 3.1 3.2 2.4 2.6 2.3 2.9 3.0 2.3 2.8 2.7 2.6 1.6 3.1 2.6 3.1 2.3 3.1 2.1 2.3 2.9 -2.1 2.6 3.1 3.1 2.7 3.2 2.6 3.0 3.3 2.6 2.6
Ulcerative Colitis 1.7 2.5 5.4 1.5 -2.1 -1.2 -1.7 -1.9 -2.3 -0.6 -0.9 -1.7 -1.9 -1.5 -1.7 -1.4 -1.5 -1.7 -1.9 -0.8 -2.3 -1.3 -1.3 -1.6 0.5 -2.1 -1.4 -0.6 -1.3 -1.9 -2.2 -0.9 -1.6 -1.2 -1.3
Blood Eosinophil Count 0.2 1.7 7.7 2.8 1.5 1.8 0.2 1.3 0.0 1.3 1.9 1.6 1.4 0.9 1.2 0.2 1.5 1.1 1.1 1.8 0.4 0.3 -0.5 0.6 -2.5 1.1 1.8 1.4 1.6 0.4 0.1 0.8 1.1 -0.3 0.9
Blood Platelet Count 0.2 2.3 22.6 4.8 0.7 -0.4 -4.7 0.1 -1.9 2.0 -0.3 0.7 -0.7 1.3 0.2 -0.7 -0.4 0.7 -1.0 -0.7 -1.3 -1.0 -1.4 -0.2 -0.5 0.4 -0.2 0.8 0.6 -1.4 -1.6 -1.7 -0.9 -0.3 -1.2
Blood Red Count 0.5 5.1 22.5 -2.9 1.5 1.1 1.7 2.3 3.1 2.4 1.0 1.9 2.1 2.9 1.9 4.1 1.7 1.3 2.3 1.1 2.8 2.6 0.9 1.9 0.3 2.3 1.6 0.7 0.9 2.9 3.3 0.8 1.8 4.7 2.6
Blood White Count 0.3 2.5 12.5 0.6 -0.1 -1.4 -3.5 0.1 1.2 2.6 -1.8 0.3 -0.4 2.2 -0.3 2.9 -0.9 -0.6 -0.1 -2.2 -0.1 1.0 -3.3 0.0 2.9 0.2 -1.0 -0.4 -1.5 0.4 1.4 -1.3 -0.7 2.7 -0.2
Heel T-Score 0.2 1.6 4.8 -0.5 1.9 1.3 1.9 1.3 1.3 0.8 1.0 1.0 1.8 0.2 1.4 0.2 1.6 1.6 1.6 0.8 2.2 0.6 1.4 0.4 -0.9 1.3 1.1 0.4 1.0 1.5 1.2 0.2 1.3 1.6 1.1
BMI 1.6 9.6 24.0 -3.7 2.7 2.0 2.9 3.3 4.0 2.0 1.6 2.9 3.4 4.2 3.2 3.5 2.8 3.5 3.3 1.6 4.2 3.0 2.1 3.0 -0.8 3.1 2.4 1.3 1.6 3.9 4.3 1.9 2.9 4.9 3.7
Height 0.4 8.6 34.2 1.9 3.1 4.3 -0.3 2.9 -0.2 2.2 4.5 3.1 2.5 1.1 2.2 1.3 3.1 1.9 2.4 5.0 0.9 0.9 2.8 2.1 -5.8 1.9 4.4 3.5 4.7 0.3 -0.6 3.4 2.7 -3.2 3.0
Waist Hip Ratio (WHR) 0.3 1.2 6.5 -1.4 1.2 0.8 -0.9 1.0 1.5 1.2 0.8 1.0 0.2 1.9 0.7 2.5 0.6 0.4 1.1 0.5 0.8 1.2 0.6 1.2 0.0 0.7 0.6 0.8 0.9 0.8 1.3 0.1 0.4 1.7 1.9
Systolic Blood Pressure 1.5 7.3 18.7 -3.0 2.5 1.5 4.3 2.7 3.4 0.9 0.9 2.3 3.0 2.6 3.3 0.2 2.4 4.1 2.8 1.0 4.0 3.7 1.9 2.3 -0.6 3.3 1.8 0.7 1.3 3.8 3.7 2.1 2.8 3.6 2.3
Smoking Status 1.0 2.4 3.6 -0.1 1.7 1.4 1.6 1.7 1.6 1.4 1.5 1.7 1.8 1.2 1.7 0.8 1.7 1.5 1.7 1.4 1.9 1.1 1.9 1.9 -0.9 1.9 1.2 1.7 1.6 1.8 1.9 1.0 1.6 1.4 1.4
Allergy or Eczema 0.1 0.4 2.0 1.0 -0.3 -0.1 -0.8 -0.5 -0.5 0.7 -0.1 -0.3 -0.4 -0.1 -0.4 -1.0 -0.4 -1.1 -0.4 -0.1 -0.8 -0.7 -1.2 0.2 -0.2 -0.5 -0.3 0.6 -0.0 -0.6 -0.4 0.4 -0.3 -1.4 -0.2
Cardiovascular Disease 3.9 13.0 26.5 -2.5 2.8 2.8 4.8 3.9 4.0 2.6 2.6 3.6 4.0 3.5 4.5 1.7 3.5 5.0 3.7 2.4 4.9 4.8 2.8 3.0 -1.2 4.4 3.0 1.7 2.6 4.6 4.6 2.7 3.6 5.2 3.6
Hypothyroidism (self reported) 0.2 0.4 2.7 -1.6 -0.3 -0.3 1.2 -0.0 0.8 -0.2 -0.8 -0.3 -0.2 -0.4 -0.1 -0.0 -0.0 0.9 0.3 -0.6 0.6 0.4 -0.1 0.4 1.1 0.0 -0.2 -0.6 -0.8 0.7 0.9 0.3 0.3 1.0 0.1
Respiratory disease 1.2 2.6 5.5 -0.1 1.3 1.8 1.9 2.0 1.1 1.1 2.0 2.1 1.6 1.2 2.2 -0.3 1.6 1.9 1.5 2.1 1.7 0.8 1.4 1.2 -1.9 2.3 2.0 1.3 2.1 1.3 1.0 2.0 1.8 -0.6 1.5
Type 2 Diabetes (T2D) (2018) 3.4 6.4 14.0 -2.4 2.9 1.9 2.7 2.7 3.3 1.8 1.5 2.3 2.3 3.1 2.8 2.3 2.5 2.1 2.8 1.0 3.5 2.2 2.0 2.7 -0.2 2.6 2.0 1.9 1.7 3.4 3.4 2.2 2.8 3.7 2.6
Lung FEV1/FVC ratio 0.6 3.0 8.6 2.1 -1.6 -0.7 -2.4 -1.7 -2.5 -1.1 -0.7 -1.5 -1.9 -1.9 -2.3 -0.4 -1.3 -2.4 -1.6 -0.2 -2.5 -1.5 -0.5 -1.6 -0.9 -2.3 -0.8 -0.6 -0.9 -2.5 -2.7 -0.9 -1.6 -2.9 -1.2
Lung FVC 0.2 0.9 3.3 -0.5 -0.9 -0.8 -0.4 -1.5 -0.2 -0.6 -1.1 -1.8 -0.7 -0.3 -1.7 0.4 -0.9 -1.7 -0.6 -1.4 -0.6 0.1 -0.9 0.3 1.2 -1.7 -0.5 -0.7 -1.4 -0.4 -0.4 0.1 -0.5 -1.0 -0.7
Neuroticism 1.7 4.0 8.2 2.5 -1.9 -1.2 -2.1 -2.2 -2.9 -2.7 -0.6 -1.8 -2.1 -1.7 -2.1 -1.7 -1.7 -2.1 -2.1 -0.7 -2.6 -2.1 -1.7 -2.5 -0.2 -2.6 -1.5 -1.4 -1.2 -2.7 -2.9 -2.0 -2.1 -1.7 -1.8
Chronotype (morning person) 8.7 20.1 32.5 1.0 -5.2 -4.9 -4.3 -5.0 -3.3 -3.6 -4.6 -5.2 -5.2 -3.6 -5.2 -1.8 -5.2 -4.6 -4.7 -5.2 -4.4 -2.5 -5.7 -4.0 4.8 -5.2 -4.9 -4.6 -5.1 -4.7 -3.6 -4.7 -5.0 -2.9 -4.5
Hair Pigment 0.4 10.6 20.2 -0.0 -3.9 -3.8 -2.8 -2.9 -2.1 -3.5 -3.9 -2.9 -3.5 -1.9 -3.1 -0.6 -4.1 -3.5 -3.5 -3.8 -2.9 -1.6 -4.5 -3.3 4.3 -2.9 -4.3 -3.7 -3.7 -3.1 -2.4 -3.8 -3.8 -0.7 -3.3
Tanning 0.3 3.7 5.8 1.6 -1.8 -1.9 -2.4 -2.1 -2.2 -2.1 -1.8 -2.0 -2.3 -0.9 -2.2 -1.2 -1.9 -1.9 -2.2 -1.7 -2.2 -1.3 -2.4 -2.1 1.1 -2.3 -1.8 -1.7 -1.7 -2.3 -2.1 -2.0 -2.1 -1.2 -1.9
Hand grip strength (left) 0.4 1.1 4.9 -0.8 1.3 1.1 0.2 1.4 1.4 0.9 0.8 1.2 1.1 1.0 0.7 2.2 1.0 0.3 1.3 1.3 1.4 0.9 1.1 0.8 -0.8 0.8 0.9 0.7 0.9 0.6 1.0 0.4 0.9 0.0 1.4
Number of treatments/medications taken 2.7 4.8 11.2 -0.6 1.9 2.1 2.0 2.5 2.0 1.9 2.1 2.7 2.4 2.0 2.8 1.3 1.9 3.3 2.2 2.2 2.5 2.5 1.7 1.8 -1.7 2.6 2.0 1.7 2.3 2.3 2.3 1.7 2.0 2.5 2.7
Average weekly spirits intake 1.1 1.4 4.6 1.7 2.1 1.5 -0.1 0.8 0.3 1.2 1.3 0.9 1.4 1.3 0.8 0.4 1.5 0.8 1.2 1.3 1.0 -0.3 1.5 1.1 -2.1 0.7 1.9 1.4 1.2 0.7 0.5 0.8 1.0 0.3 1.3
Sensitivity / hurt feelings 2.7 4.6 8.9 1.9 -2.6 -1.7 -2.8 -2.5 -2.7 -2.2 -1.1 -2.1 -2.4 -1.4 -2.6 -0.7 -2.3 -2.9 -2.5 -1.0 -2.8 -1.6 -1.4 -2.5 0.6 -2.9 -1.9 -1.7 -1.7 -3.0 -2.6 -2.0 -2.7 -1.5 -1.4
Frequency of depressed mood in last 2 weeks 1.9 2.7 5.2 -0.2 1.5 2.0 1.8 1.7 0.7 0.8 2.2 1.8 1.4 0.8 1.8 0.9 2.1 1.9 1.6 2.2 1.5 1.0 2.0 1.6 -1.9 1.8 1.8 1.9 2.3 1.6 1.0 1.4 1.8 1.8 1.4
Hearing difficulty/problems: Yes 1.0 1.5 4.3 -0.9 -2.0 -1.6 0.2 -0.9 -0.0 -1.5 -1.7 -1.1 -1.1 -0.7 -1.1 0.1 -1.4 -1.2 -0.9 -1.6 -0.4 1.0 -1.8 -0.7 1.8 -0.9 -1.6 -2.1 -1.9 -0.8 -0.4 -1.1 -1.1 -0.8 -0.9
Relative age of first facial hair 2.3 4.7 12.2 1.6 3.0 3.0 0.0 2.1 1.0 2.6 3.1 2.1 1.9 1.3 1.7 1.4 2.5 2.0 2.2 3.0 1.5 0.7 2.4 1.9 -3.5 2.0 3.0 2.6 3.1 1.0 0.9 1.9 2.0 -1.0 2.2
Other serious medical condition/disability diagnosed by doctor 0.1 0.2 1.9 0.6 -0.4 0.4 -0.1 0.3 -0.3 0.6 0.4 0.5 -0.1 -0.5 0.4 -0.2 -0.1 0.4 0.0 0.5 -0.2 0.4 -0.1 -0.1 -0.2 0.3 0.2 0.0 0.5 -0.3 -0.6 0.5 0.2 -1.4 -0.1
Ever used hormone-replacement therapy (HRT) 1.3 1.6 5.1 -0.3 -1.6 -1.5 -0.9 -1.4 -0.8 -2.2 -1.6 -1.3 -1.1 -1.1 -1.4 -0.3 -1.4 -0.8 -1.3 -1.3 -0.9 0.7 -1.5 -1.0 1.4 -1.2 -1.5 -1.8 -1.3 -1.1 -0.7 -1.5 -1.5 0.1 -1.0
Ever had hysterectomy (womb removed) 0.7 0.8 4.5 -0.2 -1.0 -1.1 -0.1 -0.9 -0.5 -2.1 -1.1 -0.9 -0.9 -0.8 -0.7 -1.0 -0.9 -0.4 -0.8 -0.8 -0.4 0.4 -1.4 -0.3 0.8 -0.9 -1.0 -1.4 -0.9 -0.6 -0.4 -1.0 -1.0 -0.1 -0.6
Systolic blood pressure, automated reading 0.3 0.8 5.7 -0.8 0.1 -0.5 1.9 0.2 0.3 -0.7 -1.0 -0.1 1.0 -0.2 0.8 -2.4 0.0 1.6 0.1 -0.8 1.2 1.6 0.3 0.0 0.2 0.8 -0.4 -1.2 -0.6 0.9 0.5 -0.1 0.2 1.1 -0.3
Eye problems/disorders: Diabetes related eye disease 1.3 1.4 3.8 -1.6 1.1 0.6 0.9 1.4 1.9 0.5 0.3 1.3 1.0 1.3 1.1 1.8 1.1 0.8 1.5 0.4 1.9 1.2 0.1 1.4 0.3 1.3 0.5 0.6 0.5 1.6 1.9 0.8 1.2 1.5 1.1
Angina 0.1 0.2 1.5 1.1 0.2 0.4 -0.5 0.0 -0.2 1.2 0.5 0.3 -0.1 -0.1 0.1 0.1 0.1 0.2 0.1 0.5 -0.2 0.0 -0.0 0.4 -0.6 -0.1 0.5 0.6 0.5 -0.2 -0.3 0.4 -0.0 -0.6 0.4
Medication for hormone replacement therapy 1.0 1.1 3.6 0.2 -0.9 -1.4 -1.9 -1.0 -0.6 -1.1 -1.1 -1.0 -1.2 -0.3 -1.1 -0.1 -1.4 -0.0 -1.3 -1.2 -1.2 0.5 -1.4 -0.7 1.1 -0.7 -1.1 -1.2 -1.0 -1.2 -0.5 -1.2 -1.4 -0.5 -0.8
Vitamin and mineral supplements 0.6 0.9 3.6 -1.9 -0.0 -0.7 0.5 0.2 1.2 -1.0 -0.8 -0.2 0.5 1.3 -0.0 1.0 -0.1 0.1 0.3 -1.3 1.1 1.5 -1.3 0.2 1.6 0.4 -0.7 -1.0 -0.8 0.8 1.2 -0.7 0.1 1.7 -0.2
Supplements: Zinc 0.3 0.3 1.3 0.7 -0.1 0.8 0.1 0.4 -0.3 0.3 0.9 0.6 0.5 -0.3 0.4 0.6 0.2 0.3 0.2 1.1 0.0 -0.3 0.4 -0.6 -1.1 0.2 0.4 0.2 0.9 -0.5 -0.6 -0.3 -0.0 -0.8 0.2
Medication: Co-codamol 1.6 1.9 3.7 1.1 -1.5 -1.2 -0.6 -1.3 -1.6 -1.1 -1.2 -1.3 -1.4 -1.9 -1.3 -0.9 -1.4 -0.9 -1.5 -1.1 -1.7 -0.3 -0.9 -1.7 0.8 -1.3 -1.3 -1.7 -1.2 -1.8 -1.9 -1.5 -1.5 -1.5 -1.7
Medication: Metformin 1.4 2.0 3.5 -1.4 1.8 1.4 1.3 1.6 1.9 0.9 1.1 1.4 1.6 1.7 1.5 1.3 1.5 1.1 1.8 0.6 1.8 0.9 0.4 1.8 -0.3 1.4 1.4 1.4 1.2 1.7 1.8 1.4 1.7 1.1 1.5
Diabetes (father) 1.9 2.3 6.2 0.4 -1.1 -1.9 -1.8 -1.1 -0.6 -1.5 -2.1 -1.3 -1.3 -0.5 -1.2 -0.3 -1.6 -1.9 -1.5 -2.3 -0.6 -1.9 -2.0 -1.6 2.3 -0.9 -2.3 -1.4 -1.4 -1.2 -0.4 -2.5 -1.7 0.5 -1.5
Diabetes (mother) 3.0 3.8 7.0 -0.3 1.9 1.9 2.6 1.9 1.4 2.2 1.7 1.6 2.2 1.0 2.4 -0.2 2.1 2.5 1.8 1.8 2.2 1.7 2.2 1.9 -1.9 1.9 2.1 2.1 1.8 2.3 1.7 2.0 2.2 2.6 2.2
Severe depression (siblings) 2.2 2.4 5.6 -0.7 1.5 1.4 1.7 1.5 1.5 1.8 1.4 1.4 2.2 1.1 1.5 0.6 1.6 1.4 1.7 1.4 1.9 1.1 2.4 1.7 -1.6 1.8 1.5 1.3 1.5 1.8 1.7 1.6 1.6 0.7 1.9
Pack years adult smoking proportion 0.6 0.9 2.5 0.2 0.4 1.1 0.9 0.6 0.0 0.4 1.1 0.7 1.1 1.6 0.8 0.0 1.1 1.0 0.7 1.0 0.5 1.3 0.9 1.1 -1.3 0.8 0.9 1.0 1.0 1.0 0.5 0.9 1.0 1.5 0.9
Impedance of leg (right) 0.3 1.5 4.1 0.8 -1.2 -1.1 -1.4 -1.2 -1.0 0.0 -0.9 -1.1 -1.6 -1.3 -1.3 -0.2 -1.5 -2.0 -1.4 -0.9 -1.7 -1.7 -1.2 -1.4 1.1 -1.1 -1.1 -0.7 -0.8 -1.5 -1.2 -0.6 -1.4 -1.8 -0.9
Leg fat-free mass (left) 1.4 7.2 11.3 -0.4 3.4 3.0 1.6 2.9 2.0 2.1 2.7 2.8 3.3 2.5 2.7 1.7 3.2 3.1 3.0 2.8 3.2 2.2 2.5 3.1 -3.3 2.6 3.2 2.7 2.9 2.6 2.2 2.3 3.0 1.8 2.9
Trunk fat percentage 1.6 6.3 11.9 -1.8 2.4 1.9 1.7 2.7 2.6 2.1 1.7 2.8 3.0 3.0 2.7 2.4 2.4 2.4 2.6 2.3 2.9 2.6 2.2 3.0 -1.8 2.7 2.1 2.2 2.1 2.8 3.0 2.1 2.2 3.3 3.5
Hand grip strength (right) 1.6 4.5 8.8 -1.7 2.7 2.1 1.2 2.6 2.7 1.5 1.4 2.2 2.5 2.4 1.9 3.0 2.3 1.6 2.7 1.8 3.0 2.2 2.1 2.1 -1.3 2.1 2.1 1.3 1.6 2.1 2.4 1.4 2.2 1.3 2.4
Townsend deprivation index at recruitment 0.3 0.5 2.0 0.4 0.2 0.9 0.9 0.4 0.0 0.7 1.4 0.5 1.1 0.6 0.8 -0.3 0.7 0.9 0.4 0.6 0.5 1.4 0.4 0.3 -1.0 0.4 0.7 0.4 1.0 0.5 0.3 0.3 0.6 0.6 0.5
Current tobacco smoking 0.2 0.4 1.1 0.6 0.8 0.8 0.7 0.5 0.2 0.1 0.8 0.5 0.6 0.3 0.5 -0.2 0.8 0.6 0.6 0.6 0.6 0.0 1.0 0.9 -0.8 0.6 0.5 0.9 0.7 0.5 0.4 0.1 0.6 0.5 0.4
Average weekly fortified wine intake 0.9 1.0 5.5 0.1 1.2 1.0 -0.4 1.0 0.7 0.4 0.9 0.9 0.6 1.6 0.9 1.6 1.1 0.6 1.0 0.6 1.1 -0.0 0.7 1.0 -0.5 0.8 1.1 1.1 1.2 1.0 1.0 0.3 1.0 2.3 1.1
Maternal smoking around birth 0.1 0.2 0.7 0.4 0.1 0.3 0.3 -0.1 -0.1 0.0 0.3 -0.2 0.3 0.7 -0.0 -0.5 0.5 -0.1 0.2 0.1 0.4 -0.4 0.2 0.7 -0.8 -0.2 0.2 0.8 0.4 0.3 0.3 0.1 0.3 0.8 0.5
Fed-up feelings 0.9 1.6 3.3 0.3 -1.7 -1.6 0.4 -1.4 -0.9 -1.6 -1.2 -1.3 -0.8 -1.3 -1.0 -1.1 -1.4 -1.0 -1.4 -1.1 -1.2 -0.9 -1.5 -1.7 1.4 -1.2 -1.8 -1.6 -1.4 -1.0 -0.8 -1.4 -1.4 0.3 -1.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.1 0.1 1.3 0.1 -0.2 0.2 0.2 0.2 -0.2 -0.6 0.5 0.3 -0.6 -0.2 0.2 0.6 0.2 0.3 0.0 0.6 -0.1 -0.2 -0.2 0.0 -0.2 0.3 -0.1 0.1 0.7 -0.1 -0.0 -0.8 -0.1 1.1 -0.0
Relative age voice broke 0.4 0.6 4.3 0.8 1.1 0.9 -0.6 0.7 0.6 2.1 1.1 0.7 0.3 0.9 0.4 1.1 0.4 0.4 0.6 0.8 0.2 -0.9 0.1 0.1 -1.0 0.7 0.8 0.7 1.1 0.1 0.4 0.5 0.3 -0.9 1.0
Taking other prescription medications 0.2 0.3 1.3 0.8 -0.3 0.3 0.6 0.3 -0.4 0.2 0.5 0.7 0.3 -0.6 0.6 -0.8 -0.0 1.0 0.0 0.7 -0.0 1.1 -0.1 -0.1 -0.8 0.5 0.0 0.0 0.5 -0.1 -0.3 0.3 0.1 -0.6 0.1
Age when periods started (menarche) 2.0 4.8 10.1 -1.8 2.5 2.6 0.2 2.6 1.9 2.3 2.3 2.8 1.4 2.3 2.2 3.2 2.0 1.7 2.4 2.7 1.5 1.4 2.6 2.3 -1.7 2.3 2.4 2.5 2.7 1.6 1.6 2.4 2.1 0.1 2.6
Bilateral oophorectomy (both ovaries removed) 0.4 0.4 2.0 -0.6 0.5 0.4 1.4 0.3 0.5 0.6 0.2 0.3 0.5 -0.5 0.5 0.2 0.7 0.4 0.6 0.6 0.5 1.3 0.9 0.6 -0.3 0.5 0.7 0.3 0.6 0.8 0.7 1.0 0.8 0.4 0.4
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 0.8 0.4 -0.1 -0.1 0.1 -0.3 -0.4 0.1 -0.1 -0.2 -0.4 -0.9 -0.2 -0.5 -0.1 -0.5 -0.3 0.0 -0.2 -0.9 0.7 -0.6 0.3 -0.3 -0.1 0.1 -0.1 -0.2 -0.2 -0.5 -0.2 0.3 -0.6
Tinnitus: Yes, but not now, but have in the past 0.5 0.6 2.7 1.3 -0.6 -0.1 -0.3 -0.3 -1.0 0.3 -0.2 -0.1 -0.7 -1.4 -0.3 -0.7 -0.4 -0.3 -0.6 0.2 -0.9 -0.4 -0.3 -1.3 -0.3 -0.5 -0.3 -1.0 -0.4 -1.1 -1.3 -0.7 -0.6 -1.6 -0.9
Qualifications: CSEs or equivalent 4.5 6.0 12.2 -0.3 -2.8 -3.1 -0.8 -3.1 -1.3 -3.0 -3.1 -3.5 -2.4 -1.6 -2.9 -2.0 -2.8 -2.7 -2.5 -3.5 -1.5 -1.9 -2.6 -1.8 3.1 -2.9 -2.9 -2.5 -3.4 -1.4 -1.2 -1.6 -2.3 -0.0 -2.4
Serious illness, injury or assault to yourself 1.4 1.7 4.8 0.8 1.1 1.6 0.8 1.1 0.2 1.4 1.8 1.2 1.5 1.4 1.4 -0.3 1.6 1.1 1.1 1.4 0.7 0.7 0.7 1.7 -1.6 1.1 1.8 2.2 1.4 1.5 0.6 2.0 1.7 0.8 0.9
High blood pressure 2.7 7.5 16.2 -1.6 2.1 2.2 3.9 2.9 2.9 2.0 2.1 2.7 2.9 2.0 3.6 0.4 2.7 4.0 2.8 2.1 3.6 3.6 1.9 2.3 -1.3 3.4 2.4 1.4 2.2 3.5 3.4 2.2 2.8 3.7 2.9
Hayfever, allergic rhinitis or eczema 0.1 0.1 0.7 0.7 -0.1 0.0 -0.3 -0.1 -0.0 0.8 0.1 -0.1 0.0 0.4 -0.1 -0.1 -0.1 -0.8 -0.1 0.1 -0.3 -0.4 -0.9 0.4 -0.2 -0.1 -0.1 0.6 0.2 0.1 0.2 0.3 -0.1 0.4 0.5
Multivitamins +/- minerals 0.3 0.3 1.3 1.1 -0.1 0.5 -0.3 -0.2 -0.9 0.5 0.6 0.1 -0.5 -0.6 0.0 -0.5 0.1 -0.1 -0.2 0.9 -1.0 -1.0 0.7 -0.5 -0.7 -0.2 0.3 0.7 0.7 -0.6 -0.9 0.3 -0.0 -0.8 -0.1
Stomach or abdominal pain in last month 0.4 0.5 3.1 0.8 -0.7 -0.8 -1.8 -0.7 -0.7 -0.2 -0.4 -0.4 -1.0 -0.1 -1.0 0.7 -0.8 -0.9 -0.8 -0.4 -0.9 -0.0 -0.7 -0.4 0.6 -0.8 -0.6 -0.5 -0.4 -1.0 -0.5 -0.8 -1.0 -0.4 -0.4
Supplements: Glucosamine 1.3 1.7 6.9 2.4 1.3 1.7 -0.4 0.8 -0.8 1.4 2.0 1.3 0.4 0.0 1.1 -0.5 1.0 0.4 0.5 2.2 -0.1 -0.6 1.1 0.6 -2.6 0.7 1.6 2.1 2.2 -0.1 -0.7 1.3 0.8 -1.4 0.8
Diverticular disease/diverticulitis (self-reported) 0.3 0.4 1.9 -0.2 -0.3 -0.5 0.5 -0.2 0.7 -0.1 -0.7 -0.4 0.8 0.7 -0.3 0.0 0.1 0.1 0.2 -1.0 1.2 0.5 -0.2 -0.2 0.2 0.3 -0.4 -1.0 -0.7 0.7 0.9 -0.7 -0.2 1.4 0.2
Medication: Atenolol 1.9 2.4 7.3 0.0 1.5 1.9 1.3 1.6 1.4 1.3 2.0 1.7 1.4 1.4 1.9 0.4 1.6 2.7 1.7 1.6 1.6 1.6 0.3 1.1 -1.3 1.5 1.9 1.4 1.4 1.5 1.3 1.9 1.8 0.3 1.7
Medication: Levothyroxine sodium 0.4 0.6 2.4 -1.0 0.6 0.7 0.8 0.7 0.9 0.8 0.6 0.7 0.6 0.2 0.8 0.4 0.7 1.5 0.9 0.6 1.0 0.7 0.2 1.3 -0.4 0.8 0.7 0.5 0.7 0.9 1.0 0.9 0.8 0.6 0.8
Sitting height 1.6 11.7 21.2 -0.7 4.0 4.3 2.5 3.8 2.2 2.3 4.0 3.8 3.8 2.5 3.8 1.0 3.9 3.7 3.6 4.3 3.3 2.0 3.5 3.3 -4.6 3.6 4.2 3.8 4.3 2.9 2.0 4.3 4.0 -0.4 3.4
Chronic bronchitis/emphysema (father) 0.5 0.6 1.5 -0.9 0.6 0.3 1.1 0.6 1.0 0.2 0.2 0.6 0.9 0.7 0.7 0.6 0.7 0.7 0.7 0.3 1.1 0.7 1.0 0.7 -0.2 0.8 0.5 -0.2 0.4 1.0 1.2 0.2 0.5 1.2 0.9
High blood pressure (mother) 0.4 0.6 3.9 0.7 -0.8 -0.5 1.1 -1.0 -0.5 -0.7 -0.8 -1.4 -0.1 -1.2 -0.8 -1.4 0.0 -0.1 -0.4 -0.8 0.1 0.2 0.2 -0.5 -0.1 -1.0 -0.5 -0.7 -1.1 0.3 -0.1 -0.4 -0.1 2.0 -0.1
Body mass index (BMI) 1.0 4.4 14.8 -2.1 1.9 1.1 2.1 2.1 2.5 1.4 0.7 1.9 2.6 2.7 2.2 1.6 2.0 2.3 2.2 1.0 3.1 2.3 1.5 2.5 -0.7 2.1 1.4 1.2 0.8 2.8 3.0 1.2 2.0 3.9 2.3
Impedance of leg (left) 0.3 1.3 3.8 1.0 -1.2 -0.8 -1.4 -1.1 -1.1 0.1 -0.6 -0.9 -1.5 -1.1 -1.1 -0.3 -1.4 -1.9 -1.3 -0.6 -1.7 -1.7 -1.0 -1.3 0.7 -1.0 -1.0 -0.5 -0.5 -1.5 -1.3 -0.6 -1.3 -1.8 -0.8
Leg predicted mass (left) 1.3 7.0 11.1 -0.4 3.3 3.0 1.6 2.9 2.0 2.1 2.6 2.7 3.2 2.5 2.7 1.6 3.2 3.0 3.0 2.7 3.1 2.3 2.5 3.1 -3.3 2.5 3.1 2.6 2.9 2.6 2.1 2.3 3.0 1.8 2.8
Trunk fat mass 1.6 6.8 12.2 -1.5 2.8 2.2 1.6 2.9 2.5 2.2 2.0 2.9 3.1 3.0 2.8 2.4 2.6 2.6 2.7 2.5 3.1 2.5 2.2 3.1 -2.2 2.7 2.4 2.4 2.3 2.8 2.9 2.1 2.5 3.2 3.5
Waist circumference 3.0 11.0 15.5 -2.2 3.5 3.0 2.4 3.7 3.2 3.1 2.6 3.6 3.8 3.7 3.7 2.8 3.4 3.5 3.5 2.9 3.8 3.4 3.0 3.9 -2.3 3.6 3.2 3.1 2.9 3.7 3.5 2.8 3.3 3.9 3.9
Number of incorrect matches in round 0.3 0.5 3.2 0.7 0.3 0.4 -1.2 0.2 -0.6 0.6 0.8 0.6 -0.3 -0.5 0.2 0.0 -0.3 -0.3 -0.2 0.8 -0.9 -0.2 -0.3 -0.7 -0.9 0.1 -0.0 0.8 1.1 -1.0 -0.9 -0.2 -0.4 -1.8 -0.0
Past tobacco smoking 1.2 2.2 4.7 0.9 -1.2 -1.0 -2.0 -1.9 -1.8 -1.4 -0.9 -1.9 -1.8 -0.5 -1.9 -1.2 -1.3 -1.9 -1.6 -1.3 -1.8 -2.1 -1.6 -1.3 0.1 -2.2 -0.8 -1.1 -1.3 -1.7 -1.9 -1.1 -1.5 -1.2 -1.2
Alcohol usually taken with meals 0.4 0.7 2.4 -0.8 1.1 0.8 0.6 1.0 1.0 1.6 0.5 0.7 1.2 0.1 0.9 0.8 0.9 0.6 1.0 0.3 1.2 0.2 0.8 0.9 -0.3 0.8 1.2 0.7 0.5 1.0 0.9 0.6 1.0 0.6 0.6
Nervous feelings 0.9 1.7 4.9 2.2 -1.0 -0.4 -1.0 -1.6 -2.1 -1.4 0.1 -1.4 -1.1 -1.2 -1.4 -1.5 -0.8 -1.1 -1.3 -0.1 -1.7 -1.2 -0.5 -1.2 -1.1 -2.0 -0.4 -0.8 -0.6 -1.8 -2.1 -0.9 -1.3 -1.9 -0.9
Frequency of tenseness / restlessness in last 2 weeks 0.9 1.5 5.2 -1.4 0.9 0.8 0.8 1.2 1.5 -0.4 0.6 1.1 0.6 2.3 1.0 2.2 1.1 1.6 1.3 0.7 1.6 1.1 0.5 0.5 -0.2 1.3 1.0 0.1 0.8 1.4 1.6 0.3 0.9 2.3 1.4
Hearing difficulty/problems with background noise 1.0 1.5 4.6 1.4 -1.2 -0.9 -1.3 -1.1 -1.4 -0.8 -0.8 -1.0 -1.3 -1.8 -1.4 -0.5 -1.1 -1.7 -1.2 -0.4 -1.3 -0.6 -1.8 -0.8 0.0 -1.5 -0.8 -0.9 -0.9 -1.8 -1.7 -1.1 -1.3 -2.1 -1.0
Hair/balding pattern: Pattern 2 0.1 0.1 0.7 0.0 -0.2 -0.5 0.5 -0.6 -0.1 -0.3 -0.1 -0.8 -0.4 0.2 -0.4 -0.8 -0.0 0.1 -0.3 -0.4 -0.4 -0.6 -0.3 -0.1 0.3 -0.2 0.2 -0.2 -0.3 0.2 0.3 0.3 0.0 0.3 -0.3
Had menopause 0.3 0.3 1.4 -0.9 0.2 0.4 1.2 0.5 0.2 0.0 0.4 0.5 0.9 -0.0 0.7 -0.0 0.4 1.1 0.4 0.7 0.4 1.0 0.5 0.0 -0.8 0.8 0.7 -0.0 0.6 0.5 0.1 0.6 0.3 0.1 0.4
Had other major operations 5.6 6.8 11.7 -0.9 2.9 2.8 3.1 2.5 2.2 2.7 2.8 2.3 2.9 1.6 2.7 0.6 3.0 2.7 2.8 2.8 2.6 1.9 3.2 2.3 -2.7 2.4 3.1 2.9 2.7 3.0 2.4 3.4 3.2 1.3 2.7
Forced vital capacity (FVC) 0.2 0.9 2.8 0.3 1.5 1.4 -0.7 0.4 0.4 1.0 1.0 0.1 1.0 0.7 -0.1 1.4 1.1 -0.1 1.0 0.7 0.8 -0.3 0.5 1.5 -1.7 -0.3 1.6 1.3 1.0 0.4 0.1 1.0 1.0 -0.8 0.9
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.2 0.9 -0.2 -0.1 -0.3 -0.3 -0.2 0.1 -0.3 -0.4 -0.4 -0.4 -0.3 -0.4 0.4 -0.1 -0.4 -0.1 -0.4 0.1 -0.4 -0.1 -0.5 0.7 -0.4 -0.4 -0.4 -0.4 -0.1 0.1 -0.9 -0.3 1.0 -0.3
Ever unenthusiastic/disinterested for a whole week 2.1 2.6 4.9 0.2 1.7 1.9 1.0 1.7 0.7 2.0 1.9 1.8 1.7 0.6 1.9 0.3 1.9 2.0 1.5 2.0 1.5 1.2 2.2 1.6 -2.2 1.8 1.4 1.8 2.0 1.3 0.9 1.0 1.5 1.5 1.7
Qualifications: None of the above 0.3 0.7 2.4 -1.3 -1.4 -1.2 -0.1 -0.6 -0.2 -1.6 -1.2 -0.5 -0.5 0.3 -0.4 -0.4 -0.9 -0.3 -0.8 -0.9 -0.3 1.4 -0.8 -0.5 1.2 -0.5 -1.3 -1.1 -1.0 -0.3 0.1 -0.8 -0.8 0.8 -0.4
Financial difficulties in last 2 years 0.7 1.0 5.0 2.2 0.4 1.1 0.5 0.5 -0.7 1.8 1.4 0.6 1.0 0.1 1.0 -1.2 0.9 0.9 0.3 1.0 0.5 0.4 1.1 1.0 -1.9 0.6 0.9 1.3 1.2 0.2 -0.4 0.4 0.6 0.4 0.3
Mouth/teeth dental problems 1.5 2.3 5.2 -1.4 2.0 1.5 1.6 1.4 1.7 1.8 1.3 1.0 1.1 0.8 1.4 1.5 1.7 1.2 1.8 1.0 1.7 -0.1 1.5 1.1 -0.4 1.4 1.7 1.7 1.5 2.0 1.7 1.6 1.8 2.3 1.5
Heart attack 0.1 0.1 0.3 0.5 -0.0 0.3 -0.5 0.2 -0.0 0.4 0.3 0.6 0.2 0.4 0.2 0.6 0.3 0.5 0.3 0.5 -0.1 0.5 -0.5 0.3 -0.2 0.1 0.2 0.4 0.1 0.0 0.0 0.1 0.1 0.3 0.2
Allergy 0.3 0.7 1.6 0.5 -0.6 -0.6 -1.3 -0.9 -1.0 -0.8 -0.4 -0.8 -0.7 -0.9 -0.9 -0.3 -0.7 -0.2 -0.8 -0.6 -1.0 -0.3 -0.0 -1.0 0.2 -1.2 -0.6 -0.8 -0.7 -1.1 -1.2 -0.9 -0.9 -1.0 -0.9
Pain all over the body in last month 0.4 0.4 3.7 -1.9 -0.5 -0.5 1.0 0.1 1.2 0.3 -0.6 -0.1 0.3 0.4 -0.0 0.8 -0.0 -0.3 0.4 -0.6 0.5 -0.1 -0.1 -0.3 1.2 0.3 -0.3 -0.5 -0.5 0.7 1.2 0.3 0.2 0.5 0.4
Diabetes (self-reported) 3.2 5.0 8.6 -1.8 2.8 2.0 1.8 2.6 2.9 1.7 1.6 2.2 2.2 2.8 2.4 2.2 2.4 2.0 2.7 1.2 2.9 1.8 1.4 2.2 -0.5 2.3 2.1 1.8 1.8 2.8 2.9 1.9 2.6 2.6 2.4
Hayfever/allergic rhinitis (self-reported) 0.2 0.3 2.1 1.0 0.2 -0.1 -0.9 -0.5 -0.2 0.8 -0.2 -0.5 -0.3 0.5 -0.4 -0.4 -0.2 -0.8 -0.2 -0.7 -0.2 -1.5 -0.2 0.2 0.1 -0.3 -0.3 0.5 -0.2 0.2 0.2 -0.0 -0.1 1.2 0.3
Medication: Ramipril 2.3 3.0 10.3 -1.2 1.1 1.6 3.2 1.7 1.1 1.0 1.6 1.8 1.9 0.3 2.3 -0.3 1.9 2.4 1.6 2.1 1.7 1.7 1.4 1.6 -1.4 1.9 1.8 1.3 1.8 2.0 1.4 1.5 1.8 2.1 1.6
Medication: Simvastatin 2.4 3.5 9.1 -2.1 1.8 1.5 0.6 2.0 2.4 1.7 1.5 2.1 1.7 3.0 2.0 2.4 1.5 2.0 2.0 1.0 2.1 2.1 1.0 1.6 -0.3 1.8 1.4 1.4 1.6 2.1 2.3 1.9 1.8 2.0 2.4
Fluid intelligence score 9.3 19.3 33.2 -0.3 5.2 5.3 2.7 4.8 3.0 5.5 5.6 5.1 4.3 3.0 4.8 2.6 4.8 4.0 4.5 5.6 3.4 1.1 5.8 4.1 -5.1 4.6 5.3 5.3 5.4 3.7 3.1 4.8 4.6 0.8 4.8
Illnesses of siblings 2.4 3.3 7.7 1.8 -1.5 -1.4 -2.1 -1.9 -2.0 -0.7 -0.8 -1.9 -1.6 -2.1 -2.0 -1.3 -1.8 -2.2 -2.0 -1.3 -1.9 -2.5 -1.6 -2.4 0.5 -2.2 -1.1 -1.3 -1.3 -2.4 -2.3 -1.6 -1.8 -2.8 -2.0
Neuroticism score 1.2 2.5 6.5 2.2 -1.7 -0.7 -1.5 -1.7 -2.5 -1.9 0.1 -1.4 -1.7 -1.5 -1.6 -1.2 -1.2 -1.6 -1.8 -0.1 -2.1 -1.7 -0.8 -1.9 -0.7 -2.1 -1.0 -0.8 -0.6 -2.3 -2.5 -1.4 -1.7 -1.4 -1.2
Weight 1.8 8.8 13.4 -1.4 3.4 2.9 2.1 3.3 2.7 2.6 2.4 3.1 3.7 3.1 3.1 2.1 3.2 3.2 3.2 2.8 3.6 2.6 2.7 3.5 -2.9 3.0 3.1 2.8 2.7 3.2 2.9 2.6 3.1 2.8 3.5
Impedance of arm (right) 0.3 1.2 9.0 1.6 -0.8 -0.1 -1.5 -0.7 -1.4 0.2 0.3 -0.3 -1.1 -1.7 -0.9 0.4 -0.9 -1.6 -1.0 0.6 -1.8 -0.5 0.2 -0.7 -0.4 -0.8 -0.3 0.3 0.5 -1.7 -1.7 0.0 -1.0 -3.0 -0.4
Arm fat percentage (right) 0.8 3.2 8.2 -1.8 1.6 0.9 1.2 1.8 2.2 1.5 0.6 1.7 2.0 2.3 1.7 2.2 1.5 1.5 1.8 1.2 2.3 2.4 1.4 2.3 -0.6 1.7 1.2 1.3 0.9 2.1 2.5 1.3 1.5 2.9 2.4
Trunk fat-free mass 0.8 4.4 9.1 -0.3 3.0 2.5 1.2 2.3 1.6 2.0 2.1 2.0 2.5 1.6 2.1 1.1 2.6 2.6 2.4 2.1 2.5 1.4 1.9 2.5 -2.8 1.9 2.7 2.2 2.3 1.9 1.5 1.8 2.4 0.9 2.1
Hip circumference 2.3 9.9 17.4 -1.0 3.5 3.0 2.6 3.6 2.6 2.8 2.8 3.5 4.2 2.8 3.5 1.8 3.4 3.5 3.3 3.2 3.8 2.6 3.0 3.5 -3.3 3.5 3.5 3.0 3.1 3.3 2.9 2.9 3.3 2.6 3.4
Time employed in main current job 0.2 0.2 2.3 -0.5 -0.2 0.0 0.5 -0.2 -0.2 0.4 -0.4 -0.3 0.3 -0.2 -0.1 -0.7 0.2 0.7 0.0 -0.2 -0.5 1.5 0.5 0.4 0.0 -0.1 -0.2 0.1 -0.2 0.4 -0.1 0.6 0.3 1.1 0.1
Alcohol intake versus 10 years previously 0.2 0.3 2.0 0.5 -1.0 -0.5 0.3 -0.8 -0.7 0.1 0.3 -0.7 -0.6 -0.2 -0.2 -1.4 -0.8 -0.5 -0.7 -0.5 -0.5 -0.2 -0.7 -0.1 0.4 -0.6 -0.2 0.2 -0.5 -0.2 -0.5 0.4 -0.3 0.2 -0.1
Father’s age at death 0.2 0.3 2.6 -0.5 0.6 0.6 -0.6 0.5 0.5 0.8 0.3 0.5 0.4 0.8 0.3 1.6 0.4 0.5 0.5 0.3 0.3 -0.0 0.1 -0.0 -0.1 0.4 0.6 0.5 0.6 0.5 0.4 0.7 0.5 0.8 0.7
Worrier / anxious feelings 1.0 2.0 4.8 1.8 -1.2 -0.8 -1.5 -1.4 -2.1 -1.5 -0.2 -1.1 -1.3 -1.4 -1.7 -0.1 -1.2 -1.6 -1.6 0.2 -2.0 -1.9 -0.6 -1.8 -0.7 -1.7 -0.9 -0.9 -0.4 -2.1 -2.2 -1.2 -1.6 -1.6 -0.8
Frequency of tiredness / lethargy in last 2 weeks 0.8 1.3 5.5 -2.0 0.4 0.0 1.5 0.8 1.9 0.2 0.1 0.5 1.0 1.5 0.7 1.6 0.5 1.7 1.0 -0.2 1.6 1.1 0.1 0.6 0.9 1.0 0.3 -0.5 -0.1 1.5 2.1 0.3 0.7 2.4 1.2
Falls in the last year 3.6 4.9 9.7 -0.8 2.5 2.4 2.4 2.2 2.0 2.5 2.3 2.0 2.2 1.6 2.2 0.9 2.7 2.1 2.5 2.0 2.3 1.3 2.9 1.7 -2.3 2.1 3.1 2.2 2.2 2.6 2.1 2.9 2.9 1.0 2.0
Hair/balding pattern: Pattern 3 0.3 0.4 4.8 2.2 0.2 0.2 -0.4 -0.3 -1.1 -0.2 0.5 -0.1 0.0 -0.4 -0.3 -1.0 0.0 -0.3 -0.4 0.5 -0.5 -0.9 -0.1 -0.6 -1.1 -0.4 0.0 0.3 0.2 -0.5 -1.0 0.0 -0.2 -0.7 -0.4
Number of live births 1.5 2.1 6.2 -1.8 1.1 1.1 2.0 1.6 2.2 0.6 0.8 1.3 1.5 1.3 1.2 2.0 1.5 1.2 1.9 0.7 2.1 2.5 0.6 1.2 0.1 1.5 1.1 0.5 0.6 1.9 2.1 1.0 1.8 1.0 1.1
Forced expiratory volume in 1-second (FEV1) 0.2 0.6 2.6 0.8 0.6 0.7 -1.5 -0.4 -0.4 0.4 0.4 -0.6 0.1 0.1 -0.9 0.8 0.4 -1.2 0.2 0.2 -0.1 -0.8 0.1 0.8 -1.4 -1.2 1.0 0.8 0.2 -0.5 -0.7 0.6 0.2 -1.6 0.3
Pulse rate 1.4 2.4 7.3 -2.3 -1.4 -2.0 -1.2 -1.3 0.7 -1.9 -2.6 -1.6 -1.2 0.3 -1.8 1.9 -1.5 -1.8 -0.8 -2.2 -0.7 0.0 -1.7 -0.8 2.7 -1.5 -1.3 -2.5 -2.2 -0.5 0.5 -1.2 -1.3 0.7 -0.5
Happiness 0.2 0.2 0.7 -0.7 0.1 0.4 0.5 0.1 0.7 0.3 0.6 0.1 0.1 0.5 0.3 0.6 0.1 0.5 0.4 0.0 0.6 0.6 -0.2 0.6 0.1 0.3 0.0 0.2 0.1 0.6 0.6 0.4 0.2 0.8 0.8
Noisy workplace 1.6 1.9 3.1 1.1 -1.6 -1.5 -1.1 -1.5 -1.5 -1.3 -1.2 -1.5 -1.7 -1.3 -1.4 -1.5 -1.3 -0.9 -1.5 -1.5 -1.4 0.3 -1.1 -1.5 1.2 -1.6 -1.4 -1.8 -1.5 -1.3 -1.4 -1.7 -1.4 0.1 -1.7
Qualifications: A levels/AS levels or equivalent 2.8 6.3 13.6 -0.4 3.4 3.4 -0.0 2.6 2.0 3.1 3.3 2.5 2.0 2.6 1.9 3.5 2.8 1.7 2.9 2.6 2.0 0.5 3.1 2.4 -2.7 2.0 3.7 2.7 2.8 1.8 1.5 2.6 2.7 0.1 2.9
Serious illness, injury or assault of a close relative in last 2 years 1.1 1.2 4.8 0.1 1.1 1.2 1.7 1.1 0.8 0.6 0.7 0.9 1.0 0.5 1.3 -0.4 1.0 2.2 1.1 0.9 1.0 0.8 0.2 0.8 -0.5 1.4 1.0 0.9 0.8 1.6 0.8 1.6 1.5 1.6 1.0
Mouth/teeth dental problems: Dentures 1.4 2.4 5.1 0.6 -2.3 -1.7 -1.4 -1.4 -1.5 -2.2 -1.4 -0.9 -1.4 -1.1 -1.3 -1.1 -1.8 -1.0 -1.7 -0.9 -1.8 0.8 -1.7 -0.9 0.8 -1.3 -2.1 -1.8 -1.6 -1.9 -1.5 -1.5 -1.9 -2.3 -1.6
Asthma 1.1 2.2 3.8 -0.6 1.4 1.7 1.8 1.7 1.3 1.0 1.4 1.5 1.4 1.3 1.7 0.5 1.6 1.4 1.7 1.4 1.9 0.7 1.4 1.2 -1.5 1.9 1.9 1.2 1.8 1.5 1.2 1.9 1.8 -0.2 1.4
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.2 1.3 0.5 0.6 0.1 -0.5 0.1 0.5 0.4 0.2 0.0 0.2 0.5 0.2 0.0 0.0 0.1 0.2 -0.2 0.5 -0.7 -0.1 0.2 0.1 0.1 -0.1 0.7 0.3 0.4 0.7 0.1 0.1 1.1 0.7
Medication: Cholesterol lowering 0.8 1.2 3.2 -0.9 0.9 0.7 -0.0 1.3 1.4 1.8 0.8 1.5 0.7 1.6 1.4 1.6 0.6 1.2 1.0 0.7 1.0 1.1 0.8 1.0 -0.0 1.2 0.5 1.0 1.0 0.9 1.4 0.9 0.7 1.2 1.7
Depression (self-reported) 1.4 1.7 3.8 -0.0 -1.6 -1.0 -1.5 -1.6 -1.4 -1.2 -0.8 -1.4 -1.8 -0.9 -1.6 -0.3 -1.6 -1.8 -1.4 -0.9 -2.0 -0.9 -1.5 -1.2 0.7 -1.8 -1.5 -0.7 -0.9 -1.6 -1.5 -1.1 -1.7 -0.3 -0.5
Medication: Lansoprazole 0.2 0.3 2.4 -1.5 -0.5 -0.6 0.5 -0.0 0.7 -0.4 -0.8 -0.1 -0.2 -0.1 -0.4 0.9 -0.2 -0.3 0.1 -0.2 -0.1 1.0 0.0 0.0 0.7 0.2 -0.4 -0.5 -0.4 0.1 0.7 0.3 -0.1 -0.8 -0.0
Prospective memory result 4.7 5.7 9.7 0.8 -2.6 -2.8 -2.4 -2.8 -1.8 -2.4 -2.4 -2.7 -2.9 -1.4 -2.6 -1.6 -2.8 -2.4 -2.7 -3.1 -2.1 -2.3 -2.7 -2.2 2.7 -2.3 -2.9 -2.3 -2.3 -2.3 -1.6 -2.6 -2.7 -1.0 -2.4
Lung cancer (father) 1.7 2.0 4.2 -0.8 1.4 1.2 2.0 1.6 1.2 0.0 1.0 1.5 1.5 1.2 1.5 0.9 1.8 1.8 1.6 1.6 1.8 1.5 1.3 1.1 -1.3 1.9 1.2 0.9 1.5 1.8 1.5 0.8 1.5 2.0 1.2
Illnesses of mother 1.0 1.2 4.8 0.0 -0.7 -0.9 -2.2 -0.8 -0.9 -1.7 -0.6 -0.6 -1.6 0.3 -1.1 0.1 -1.1 -1.3 -1.0 -0.6 -1.6 -1.3 -1.8 -0.5 0.8 -0.8 -1.2 -0.4 -0.4 -1.4 -1.0 -0.9 -1.2 -1.6 -1.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.7 2.5 0.3 1.1 1.0 -0.7 0.1 0.4 0.8 0.8 0.0 0.7 0.6 -0.3 1.2 0.8 -0.4 0.7 0.8 0.4 0.2 0.2 1.4 -1.6 -0.5 1.4 1.2 0.8 0.3 0.2 1.4 0.8 -1.2 0.9
Pulse wave Arterial Stiffness index 0.6 0.7 1.8 0.1 -0.7 -1.0 -0.7 -0.9 -0.6 -0.6 -1.0 -0.9 -0.8 -0.9 -1.1 -0.1 -0.9 -0.6 -0.8 -0.9 -1.0 -0.4 -1.3 -0.9 1.0 -1.1 -0.6 -1.0 -0.9 -0.8 -0.7 -0.5 -0.7 -0.8 -1.0
Impedance of arm (left) 0.2 0.8 5.4 1.4 -0.4 0.3 -0.9 -0.3 -1.2 0.3 0.8 0.2 -0.7 -1.2 -0.2 -0.0 -0.4 -0.9 -0.6 1.1 -1.5 -0.7 0.8 -0.4 -0.8 -0.1 0.1 0.7 1.0 -1.1 -1.2 0.6 -0.4 -2.3 0.0
Arm fat mass (right) 1.0 4.1 9.5 -1.7 2.0 1.4 1.4 2.1 2.2 1.6 1.0 2.0 2.4 2.5 2.0 2.0 1.9 2.0 2.1 1.4 2.6 2.2 1.6 2.5 -1.2 1.9 1.6 1.6 1.2 2.4 2.6 1.6 1.9 3.1 2.6
Trunk predicted mass 0.7 3.7 8.1 -0.1 2.8 2.3 0.9 2.1 1.4 1.9 1.9 1.8 2.3 1.4 1.9 0.9 2.4 2.4 2.2 1.9 2.2 1.2 1.7 2.3 -2.7 1.7 2.6 2.1 2.2 1.7 1.3 1.6 2.2 0.7 2.0
Standing height 0.7 7.2 22.3 1.1 3.5 3.8 0.1 2.7 0.6 2.7 3.8 2.8 2.4 1.3 2.4 1.4 2.9 2.3 2.5 3.9 1.5 0.8 2.7 2.3 -4.7 2.2 3.9 3.4 4.2 1.1 0.3 3.0 2.7 -1.7 2.7
Length of working week for main job 0.6 0.7 2.3 0.6 1.1 1.0 -0.0 0.8 0.3 1.3 0.7 0.7 0.9 0.9 0.7 0.1 0.9 0.8 0.7 0.7 0.9 -0.7 0.8 0.3 -1.5 1.0 1.0 1.0 0.8 0.6 0.2 1.0 0.8 -0.0 0.9
Exposure to tobacco smoke at home 0.9 1.0 3.5 -1.4 0.8 0.3 1.2 1.1 1.4 0.7 0.2 1.0 0.4 1.3 1.3 0.7 0.6 1.7 0.8 0.3 1.5 0.9 0.2 0.7 0.4 1.4 0.6 0.4 0.5 1.3 1.5 0.6 0.9 1.9 0.7
Breastfed as a baby 0.1 0.2 0.6 -0.4 0.5 0.4 0.8 0.5 0.0 0.2 0.3 0.5 0.3 -0.5 0.6 -0.3 0.2 0.6 0.2 0.4 0.4 -0.3 0.6 0.2 -0.3 0.6 0.3 0.3 0.6 0.2 -0.1 0.1 0.3 -0.3 -0.1
Tense / ‘highly strung’ 4.1 6.8 10.9 2.1 -2.9 -2.4 -2.4 -3.2 -3.2 -2.4 -2.0 -2.8 -3.2 -2.0 -2.7 -2.2 -2.7 -2.9 -3.1 -2.1 -3.2 -2.2 -2.0 -3.0 1.7 -3.3 -2.8 -2.1 -2.3 -2.9 -2.9 -3.0 -3.1 0.1 -2.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.5 4.0 1.7 0.0 0.8 -0.4 -0.2 -0.8 0.3 0.9 0.1 0.3 -0.3 -0.3 -0.2 0.4 -0.0 0.0 1.0 -0.3 -0.0 0.7 0.5 -2.0 -0.3 0.5 0.6 0.6 -0.6 -0.7 -0.1 -0.2 -0.9 0.6
Hair/balding pattern: Pattern 4 0.8 1.9 4.5 0.0 1.5 2.0 -0.1 1.4 0.6 1.4 1.9 1.6 1.2 1.0 1.4 1.0 1.6 0.9 1.4 1.8 0.6 2.0 1.1 1.4 -2.0 0.9 1.6 1.9 2.1 0.7 0.3 1.6 1.5 -0.8 1.2
Birth weight of first child 0.6 1.1 5.1 2.2 1.1 1.3 -1.9 0.1 -1.4 0.4 1.2 0.4 -0.2 -0.0 0.0 -0.2 0.7 -0.1 0.1 1.3 -0.9 -1.4 0.7 -0.2 -2.2 -0.5 0.6 1.4 1.2 -1.0 -1.5 -0.4 0.0 -1.1 0.1
Peak expiratory flow (PEF) 0.2 0.5 2.4 1.3 0.8 0.7 -1.2 -0.1 -0.4 0.8 0.5 -0.3 0.4 0.6 -0.5 0.5 0.7 -0.7 0.3 0.1 0.2 -0.0 0.2 1.0 -1.5 -0.7 1.3 0.8 0.2 -0.2 -0.6 0.6 0.5 -0.8 0.3
Pulse wave reflection index 0.9 1.1 2.5 1.0 -0.4 -0.9 -1.3 -1.2 -0.8 -0.7 -0.9 -1.3 -0.9 -1.2 -1.6 -0.2 -0.8 -1.2 -0.8 -1.2 -0.8 -1.2 -1.5 -1.3 0.6 -1.3 -0.7 -0.9 -1.2 -1.1 -1.0 -1.1 -0.9 -1.1 -1.2
Ever highly irritable/argumentative for 2 days 0.1 0.1 1.1 0.2 0.0 -0.1 0.0 -0.3 -0.1 -0.6 0.0 -0.6 -0.2 0.1 -0.5 0.4 -0.0 -0.3 -0.1 -0.5 0.5 -0.3 -0.3 -0.2 0.1 -0.4 -0.3 -0.4 -0.4 -0.1 -0.2 -1.0 -0.4 0.7 -0.0
Loud music exposure frequency 1.5 1.6 3.8 0.9 -1.1 -1.3 -0.7 -1.9 -1.3 -1.4 -1.2 -1.9 -0.9 -0.4 -1.6 -1.5 -1.3 -1.3 -1.4 -1.7 -1.2 -0.9 -0.9 -1.3 0.8 -1.7 -1.2 -1.2 -1.7 -0.9 -1.0 -1.5 -1.4 0.7 -1.1
Qualifications: O levels/GCSEs or equivalent 1.5 2.4 5.8 0.1 2.4 2.1 -0.5 1.7 1.2 1.5 2.1 1.7 1.1 1.7 1.2 2.2 1.8 0.7 1.9 1.4 1.1 -0.5 1.2 1.9 -1.6 1.4 2.0 2.1 1.9 1.2 1.0 1.2 1.6 0.6 1.6
Mouth/teeth dental problems: Bleeding gums 1.6 2.1 4.3 -1.0 1.4 1.4 0.6 1.6 1.8 1.5 1.3 1.4 1.6 2.1 1.5 1.1 1.5 1.6 1.7 1.0 1.7 1.3 0.8 1.6 -0.8 1.4 1.6 1.3 1.3 1.5 1.8 1.6 1.7 0.5 1.6
Blood clot in the leg (DVT) 0.8 1.0 3.6 -1.1 0.8 0.5 1.1 1.5 1.6 0.3 0.0 1.4 0.7 1.3 1.2 1.4 0.8 1.0 1.1 0.5 1.4 1.9 0.2 0.8 0.3 1.8 0.5 0.2 0.5 1.1 1.4 0.6 0.9 0.2 0.6
Medication: Paracetamol 0.1 0.1 1.1 0.2 0.1 -0.0 -0.3 -0.1 -0.3 -1.1 0.3 0.0 0.2 0.9 0.3 -0.4 -0.4 0.3 -0.3 -0.0 -0.1 -0.7 -0.5 -0.6 -0.3 0.0 -0.0 -0.2 0.2 -0.2 -0.1 -0.3 -0.4 0.5 0.4
Headache pain in last month 4.1 7.0 10.7 1.0 -2.8 -3.0 -2.9 -2.8 -2.1 -2.8 -2.8 -2.9 -3.2 -1.8 -2.9 -1.0 -3.3 -2.2 -2.9 -3.1 -2.4 -2.1 -2.7 -2.9 2.5 -2.7 -3.2 -3.0 -2.9 -2.8 -2.2 -3.1 -3.3 -0.8 -2.1
Medication for cholesterol, blood pressure or diabetes 1.5 2.5 5.5 1.9 -1.1 -0.7 -1.4 -1.9 -2.2 -1.9 -0.9 -2.0 -1.3 -1.9 -2.2 -1.3 -0.9 -2.1 -1.5 -1.0 -1.8 -1.9 -1.2 -1.4 -0.2 -2.1 -1.0 -0.9 -1.2 -1.8 -2.3 -1.2 -1.2 -1.8 -1.8
Glaucoma (self-reported) 1.4 1.6 3.6 0.3 -1.1 -1.4 -1.8 -1.4 -0.9 -0.6 -1.0 -1.3 -1.1 -0.4 -1.4 -0.3 -1.5 -1.2 -1.3 -1.6 -1.3 -1.4 -1.9 -1.9 1.3 -1.5 -1.4 -1.2 -1.1 -1.3 -0.9 -1.5 -1.5 -0.4 -0.9
Gout (self-reported) 0.2 0.3 1.9 -1.4 0.2 -0.2 0.5 0.2 0.6 -1.0 -0.2 0.2 0.2 0.9 0.3 0.2 0.1 -0.1 0.2 0.1 0.4 -0.7 -0.1 0.7 0.6 0.5 -0.3 0.1 0.0 0.5 0.9 0.1 0.1 1.1 0.3
Hypothyroidism/myxoedema (self-reported) 0.1 0.3 1.3 -0.8 0.3 0.4 1.0 0.5 0.6 0.2 0.2 0.4 0.1 0.0 0.5 0.2 0.5 1.2 0.6 0.4 0.8 0.2 0.2 0.5 0.0 0.5 0.3 0.2 0.2 0.7 0.7 0.6 0.6 0.6 0.6
Medication: Amlodipine 13.5 18.9 27.9 -2.8 4.3 4.1 5.3 4.5 4.6 3.8 4.0 4.4 4.8 3.7 4.9 2.3 4.8 4.4 4.8 4.0 5.0 3.6 4.4 4.6 -3.2 4.8 4.4 4.3 4.2 5.3 5.1 4.5 4.9 3.7 4.3
Medication: Ventolin 100micrograms inhaler 0.1 0.1 0.6 -0.5 -0.0 0.4 0.6 0.3 0.1 -0.1 0.3 0.4 0.2 0.3 0.4 -0.3 0.0 -0.0 0.2 0.4 0.1 -0.2 0.8 0.1 -0.4 0.2 0.3 0.0 0.3 -0.1 -0.1 0.3 0.2 -0.6 0.2
Birth weight 2.2 4.8 10.2 2.0 -1.5 -1.8 -2.9 -2.2 -2.4 -1.6 -1.9 -2.1 -2.5 -1.9 -2.6 -0.8 -2.2 -2.6 -2.3 -1.5 -2.7 -3.2 -2.3 -2.7 0.8 -2.5 -2.1 -1.6 -1.8 -2.7 -2.6 -2.4 -2.5 -1.5 -1.7
Chronic bronchitis/emphysema (mother) 2.1 2.4 5.7 0.3 -1.8 -1.6 -1.0 -1.6 -1.6 -2.4 -1.4 -1.4 -1.8 -1.8 -1.5 -1.0 -1.6 -1.4 -1.7 -1.1 -1.7 -1.3 -1.0 -1.5 1.1 -1.6 -2.0 -1.7 -1.5 -1.8 -1.6 -2.1 -1.9 -0.6 -1.6
High blood pressure (siblings) 0.6 0.9 5.8 0.5 0.8 0.6 1.5 0.7 0.4 0.1 -0.1 0.6 1.2 0.1 0.9 -0.5 1.1 1.5 0.8 0.8 1.1 1.4 0.7 1.1 -1.0 1.0 0.6 0.4 0.5 1.2 0.8 0.4 0.7 2.4 1.1
Forced vital capacity (FVC), Best measure 0.6 2.3 5.4 -0.3 2.0 1.9 0.2 1.1 1.3 1.6 1.6 0.9 1.8 1.4 0.7 2.0 1.8 0.5 1.7 1.4 1.5 1.0 1.0 2.3 -2.0 0.6 2.1 1.9 1.6 1.3 1.1 2.0 1.7 -0.4 1.7
Body fat percentage 1.4 5.5 11.4 -1.9 2.2 1.6 1.5 2.6 2.6 2.1 1.4 2.5 2.7 3.0 2.5 2.5 2.2 2.1 2.4 1.9 2.9 2.5 1.9 2.9 -1.4 2.5 1.8 1.9 1.7 2.7 3.0 1.8 2.0 3.4 3.2
Leg fat percentage (right) 0.7 2.6 9.7 -2.0 1.3 0.5 1.1 1.6 2.3 1.4 0.1 1.4 1.9 2.2 1.5 1.8 1.1 1.2 1.5 0.5 2.3 1.7 0.7 1.9 -0.1 1.7 0.7 0.8 0.4 2.1 2.6 0.9 1.2 3.1 2.1
Arm fat-free mass (right) 1.2 6.0 10.4 -0.5 3.2 2.7 1.5 2.7 1.9 2.1 2.3 2.5 2.9 2.5 2.6 1.0 3.0 2.9 2.7 2.3 2.9 1.4 2.0 2.8 -3.0 2.4 3.0 2.5 2.5 2.5 2.0 2.1 2.8 2.0 2.6
Exposure to tobacco smoke outside home 0.4 0.5 3.1 -1.1 -0.9 -0.7 1.8 -0.4 0.0 -1.3 -0.8 -0.5 0.1 -0.7 0.1 -0.9 -0.4 0.7 -0.4 -0.4 0.2 1.3 0.1 -0.0 0.8 0.0 -0.6 -0.8 -0.8 0.4 0.3 -0.1 -0.2 1.3 -0.3
Comparative body size at age 10 0.6 1.5 3.7 0.8 -1.1 -1.0 -1.0 -1.6 -1.2 -0.9 -0.9 -1.7 -1.2 -1.1 -1.5 -1.2 -1.2 -1.8 -1.2 -1.6 -1.3 -1.2 -1.1 -1.2 1.1 -1.9 -1.3 -0.5 -1.3 -1.1 -1.2 -0.9 -1.0 -0.7 -1.6
Number of full brothers 0.5 0.6 5.4 -0.3 0.3 0.2 1.7 0.7 0.7 -0.5 0.1 0.5 0.8 0.9 0.9 0.1 0.7 0.9 0.6 0.1 1.1 0.8 0.1 -0.2 0.1 0.7 0.3 -0.3 0.2 1.1 0.9 -0.2 0.6 2.3 0.4
Worry too long after embarrassment 0.7 1.3 5.8 -0.3 1.1 1.5 0.4 1.2 0.9 1.0 1.4 1.1 1.0 1.0 0.7 2.4 1.2 0.9 1.3 1.3 1.0 1.0 1.1 0.7 -1.4 0.9 1.4 0.8 1.1 0.8 0.7 0.9 1.1 0.7 1.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.6 1.8 0.6 -0.7 -0.1 -1.3 -0.6 -1.2 -0.1 0.1 -0.3 -1.1 -0.9 -0.9 0.9 -0.7 -1.0 -0.8 0.3 -1.2 -0.8 0.1 -0.6 -0.2 -1.0 -0.8 -0.0 0.2 -1.3 -1.2 -1.0 -1.1 -0.2 0.0
Wheeze or whistling in the chest in last year 1.5 2.8 8.8 -2.3 1.0 0.5 3.0 1.7 2.5 0.2 0.4 1.3 1.6 1.9 1.7 0.7 1.2 2.3 1.6 0.4 2.6 2.2 0.5 1.4 0.3 2.4 0.9 -0.0 0.7 2.3 2.8 1.3 1.6 1.4 1.4
Number of children fathered 0.3 0.3 1.5 1.2 0.2 0.0 -0.8 -0.8 -0.3 0.2 0.2 -0.8 -0.1 0.3 -0.7 -0.8 0.1 -0.9 -0.1 -0.4 -0.4 -0.7 -0.3 0.5 -0.7 -1.0 -0.0 0.3 -0.5 -0.3 -0.2 0.3 -0.1 -1.1 -0.0
Reason for reducing amount of alcohol drunk: Health precaution 0.6 0.7 1.6 0.9 -0.7 -0.9 -0.5 -1.0 -0.6 0.1 -0.7 -0.9 -0.7 -0.9 -0.8 -1.0 -1.1 -1.0 -0.9 -0.7 -1.1 -0.7 -1.2 -1.3 0.7 -1.1 -0.8 -0.6 -0.9 -1.0 -0.7 -0.4 -1.0 -1.2 -0.6
Age at first live birth 1.3 2.3 8.6 1.5 2.2 2.1 -0.8 1.4 -0.1 2.1 2.2 1.4 1.1 0.4 1.1 0.2 1.3 1.7 1.1 2.0 0.1 -0.5 1.7 0.1 -2.9 1.2 2.0 1.4 2.4 0.0 -0.6 1.5 1.1 -2.0 1.4
Pulse wave peak to peak time 0.8 1.0 2.1 0.3 1.0 1.3 0.6 1.1 0.4 0.8 1.3 1.2 0.9 0.9 1.3 0.0 1.1 0.8 0.9 1.3 1.0 0.4 1.4 1.0 -1.4 1.2 0.9 1.2 1.3 0.8 0.5 0.7 0.8 0.5 1.1
Health satisfaction 0.3 0.4 1.4 -0.8 0.7 0.4 0.6 0.8 0.9 0.5 0.3 0.8 0.6 0.8 1.1 0.3 0.4 1.0 0.7 0.2 0.8 -0.3 0.1 0.5 0.0 0.9 0.1 0.3 0.5 0.8 0.8 0.0 0.3 1.2 0.8
Shortness of breath walking on level ground 0.3 0.4 1.2 -0.1 -0.6 -0.6 -0.8 -0.7 -0.5 -1.0 -0.3 -0.8 -0.8 0.8 -0.5 -0.5 -0.7 -0.3 -0.6 -1.0 -0.6 -0.8 -1.1 -0.9 0.8 -0.6 -0.5 -0.5 -0.4 -0.4 -0.4 -0.2 -0.5 0.1 -0.3
Qualifications: College or University degree 1.6 4.9 13.6 1.3 3.3 3.1 0.4 2.2 0.6 3.2 2.9 2.4 2.1 0.2 1.8 1.2 2.7 1.4 2.2 3.0 1.0 -1.8 3.6 1.1 -3.7 1.9 3.2 2.4 3.0 1.0 0.2 1.8 2.2 -1.5 1.6
Eye problems/disorders: None of the above 0.1 0.1 0.8 0.3 -0.2 -0.1 0.5 -0.3 -0.6 -0.3 0.0 -0.4 -0.2 -0.5 -0.1 -0.9 -0.2 -0.3 -0.4 -0.2 -0.2 -0.5 0.3 -0.3 0.0 -0.2 0.2 -0.1 -0.2 -0.2 -0.7 0.0 -0.1 -0.1 -0.5
Mouth/teeth dental problems: Loose teeth 0.2 0.2 1.1 0.8 0.1 0.3 0.2 0.1 -0.5 -0.2 0.3 0.4 0.4 -0.3 0.2 -0.4 0.5 -0.3 0.0 0.9 0.0 0.6 0.6 0.3 -0.8 0.1 0.1 1.0 0.3 -0.0 -0.4 0.4 0.2 -0.2 -0.2
Emphysema/chronic bronchitis 1.7 1.9 4.6 -1.4 1.0 1.1 2.1 1.7 1.3 0.9 1.4 1.9 1.4 1.2 2.0 0.6 1.2 1.9 1.3 1.6 1.3 0.6 0.5 1.4 -0.7 1.9 1.3 1.1 1.3 1.7 1.4 1.6 1.5 1.2 1.2
Medication for pain relief, constipation, heartburn 0.5 0.8 3.3 -0.7 -0.9 -0.8 -0.5 -0.9 -0.3 -0.5 -1.0 -1.3 -0.9 -0.9 -1.6 0.5 -0.5 -1.8 -0.6 -1.1 -0.4 -0.0 -0.1 -0.4 0.9 -1.3 -0.7 -1.2 -1.3 -0.7 -0.6 -1.0 -0.6 -0.5 -1.0
Neck or shoulder pain in last month 1.6 2.2 4.4 1.3 -1.5 -1.8 -1.7 -1.5 -1.0 -0.7 -1.7 -1.7 -1.8 -0.5 -1.7 -0.5 -1.6 -1.7 -1.5 -2.1 -1.0 -1.9 -2.0 -1.4 1.3 -1.6 -1.7 -1.4 -1.8 -1.3 -0.9 -2.0 -1.6 0.3 -1.2
Medication: Blood pressure 3.3 5.9 11.2 -2.1 1.9 1.7 2.8 2.8 2.9 2.4 1.9 3.0 2.2 2.2 3.4 1.2 2.0 3.2 2.4 2.3 2.6 2.5 2.2 2.5 -0.8 3.1 2.0 1.8 2.2 2.8 3.1 2.3 2.3 2.3 2.7
Angina (self-reported) 0.1 0.1 1.2 1.1 -0.1 0.1 -0.6 -0.3 -0.4 0.8 0.2 0.0 -0.4 -0.4 -0.2 -0.1 -0.2 -0.1 -0.2 0.2 -0.4 -0.1 -0.2 0.0 -0.3 -0.3 0.1 0.3 0.2 -0.4 -0.5 -0.0 -0.3 -0.4 0.2
Migraine (self-reported) 0.2 0.3 2.4 -0.9 -0.2 -0.4 1.6 0.1 1.0 -0.4 -0.3 -0.0 -0.0 -0.1 0.2 -0.1 -0.1 0.3 0.2 -0.2 0.8 0.6 0.5 0.3 0.7 0.4 -0.6 -0.5 -0.7 0.5 1.0 -0.3 -0.1 0.4 0.3
Medication: Ibuprofen 0.2 0.3 1.3 0.1 0.7 -0.1 -0.8 -0.1 0.9 0.2 -0.1 -0.4 0.1 0.5 -0.3 0.8 -0.0 -0.1 0.3 -0.6 0.8 -0.6 -0.2 0.2 0.4 -0.1 -0.2 0.2 -0.1 0.4 1.0 -0.4 -0.1 1.2 0.9
Medication: Allopurinol 0.1 0.2 1.0 -0.6 0.5 0.2 -0.1 0.2 -0.0 -0.8 0.4 0.3 0.1 0.9 0.4 -0.1 0.3 -0.2 0.1 0.4 0.0 -0.9 -0.1 1.0 -0.0 0.3 0.0 0.7 0.5 0.2 0.3 0.1 0.1 0.7 0.2
Medication: Omeprazole 0.2 0.2 0.8 -0.2 -0.7 -0.7 -0.5 -0.2 -0.1 -0.2 -0.4 0.0 -0.3 0.6 0.0 -0.2 -0.6 0.2 -0.5 -0.4 -0.0 0.9 -0.8 0.2 0.7 -0.0 -0.4 -0.4 -0.5 -0.3 -0.0 -0.4 -0.6 0.2 -0.2
Medication: Seretide 50 evohaler 2.6 3.0 5.1 -0.4 1.9 2.1 1.6 1.9 1.4 0.7 2.0 1.9 1.7 1.3 1.9 0.8 2.1 1.7 2.0 1.9 1.9 1.6 2.0 2.3 -1.9 1.9 2.0 1.7 1.8 1.7 1.3 1.7 2.0 0.3 1.7
Mean time to correctly identify matches 6.4 12.3 16.2 1.7 -3.9 -3.5 -3.0 -3.7 -3.8 -3.9 -3.2 -3.4 -3.8 -3.7 -3.5 -3.0 -3.7 -3.1 -3.9 -3.0 -4.0 -3.0 -3.1 -3.8 2.7 -3.6 -3.7 -3.5 -3.2 -4.0 -3.8 -3.9 -4.0 -2.7 -4.0
Heart disease (mother) 1.8 2.2 5.4 -0.3 1.4 1.3 1.6 1.6 0.9 2.3 1.4 1.5 1.8 0.6 1.7 0.7 1.3 1.5 1.3 1.3 1.4 2.1 1.5 1.0 -0.9 1.6 1.4 1.5 1.5 1.7 1.1 1.7 1.6 1.9 1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.4 4.9 -0.3 -0.2 -0.3 0.7 0.2 0.4 -0.5 -0.3 -0.0 0.8 0.9 0.3 0.0 0.1 0.2 0.2 -0.7 0.9 0.6 -0.8 0.0 0.6 0.4 -0.2 -0.6 -0.4 0.8 0.7 -0.7 0.1 2.2 0.2
Whole body fat mass 1.5 6.1 10.5 -1.5 2.6 2.1 1.5 2.7 2.5 2.1 1.7 2.7 3.0 3.0 2.6 2.3 2.5 2.4 2.6 2.2 3.0 2.3 2.0 3.0 -1.9 2.6 2.2 2.2 2.0 2.7 2.8 2.0 2.3 3.1 3.2
Leg fat mass (right) 1.2 4.6 10.5 -1.7 2.3 1.5 1.3 2.3 2.4 1.9 1.1 2.2 2.5 2.7 2.2 2.1 2.1 2.1 2.3 1.5 2.8 2.0 1.5 2.6 -1.3 2.2 1.7 1.7 1.4 2.5 2.8 1.6 2.0 3.2 2.8
Arm predicted mass (right) 1.2 6.0 10.2 -0.8 3.2 2.7 1.5 2.7 2.0 2.1 2.3 2.4 2.9 2.4 2.5 1.3 3.0 3.0 2.8 2.2 3.0 1.5 2.1 2.8 -2.8 2.4 2.9 2.4 2.5 2.5 2.1 2.1 2.8 2.0 2.6
Pulse rate, automated reading 0.9 2.9 20.8 -4.6 0.9 -0.1 -0.0 1.5 3.0 0.4 -1.0 1.2 0.9 2.4 0.5 4.1 0.5 0.7 1.6 -0.4 1.4 1.8 0.7 1.7 1.5 1.4 0.3 -0.7 0.1 1.6 2.7 0.5 0.7 1.5 1.7
Alcohol intake frequency. 1.6 3.7 7.3 0.4 -2.7 -2.0 -1.8 -2.1 -2.1 -2.4 -1.4 -2.1 -2.1 -1.1 -2.3 -0.6 -2.2 -2.1 -2.2 -1.8 -2.0 -0.7 -1.9 -2.3 1.1 -2.1 -2.1 -2.3 -1.8 -2.1 -2.1 -2.1 -2.2 -1.1 -1.9
Comparative height size at age 10 0.2 1.0 3.5 0.5 -1.4 -0.8 -0.5 -0.9 -1.2 -1.2 -0.8 -0.9 -0.3 -1.2 -1.0 -0.6 -1.1 -0.7 -1.1 -0.6 -1.0 0.3 -1.9 -1.3 0.3 -1.1 -0.7 -1.1 -0.8 -1.2 -1.4 -0.6 -0.9 -1.1 -0.9
Number of full sisters 4.6 5.5 9.7 -2.7 2.0 2.0 2.5 2.6 3.0 2.0 2.1 2.4 2.3 1.8 2.5 2.8 2.3 2.4 2.6 1.9 2.9 3.1 1.6 3.0 -0.5 2.3 1.9 2.1 1.9 2.6 3.0 1.7 2.5 1.8 2.3
Suffer from ‘nerves’ 3.4 5.3 11.8 2.4 -2.3 -1.5 -2.5 -2.6 -3.3 -1.9 -0.5 -2.2 -2.9 -1.8 -2.2 -2.1 -2.2 -2.3 -2.7 -1.1 -3.4 -2.7 -1.8 -2.9 0.1 -2.9 -1.5 -1.6 -1.3 -2.9 -3.4 -1.7 -2.4 -1.9 -2.1
Overall health rating 1.2 2.6 5.9 -1.2 0.9 1.1 2.1 1.9 1.9 0.9 1.1 2.0 1.7 2.1 2.3 0.9 1.4 2.0 1.6 1.0 2.0 1.7 0.2 1.4 -0.2 2.1 1.1 0.7 1.2 2.1 2.1 1.4 1.6 2.4 1.6
Chest pain or discomfort 4.8 6.9 10.3 -0.7 2.9 2.7 1.7 3.2 2.7 3.0 2.5 3.2 2.6 2.1 2.9 2.5 2.8 2.9 3.0 2.9 3.0 2.5 2.9 2.3 -2.6 3.2 2.7 2.2 3.0 2.2 2.6 2.2 2.5 0.7 3.0
Had major operations 2.7 3.1 5.2 0.4 -1.8 -2.1 -2.0 -1.9 -1.2 -1.5 -1.8 -1.9 -2.3 -1.2 -2.0 -0.7 -2.2 -1.8 -1.9 -2.0 -1.8 -1.3 -2.2 -1.1 2.2 -2.2 -2.0 -1.9 -2.0 -1.9 -1.2 -2.0 -2.1 -0.5 -1.3
Age at last live birth 2.4 3.5 7.4 0.5 2.0 2.5 0.8 2.1 1.0 2.7 2.5 2.0 2.3 0.4 1.8 1.0 2.0 2.5 1.9 2.4 1.4 2.2 1.8 1.0 -2.7 1.9 2.2 1.6 2.4 1.1 0.5 2.2 2.0 -1.3 1.9
Family relationship satisfaction 0.3 0.4 2.8 0.8 -0.1 -0.4 -1.7 -0.5 -0.5 0.1 0.1 -0.3 -0.7 0.3 -0.8 0.7 -0.5 -0.7 -0.5 -0.2 -0.5 -1.4 -0.6 -0.7 0.0 -0.5 -0.2 -0.2 0.1 -0.8 -0.5 -1.0 -0.9 0.1 -0.0
Leg pain on walking 0.5 0.6 2.6 1.1 -0.4 -0.4 0.1 -0.7 -1.2 0.1 -0.9 -0.5 -0.7 -1.2 -0.3 -1.6 -0.6 -0.5 -0.8 -0.2 -0.9 -1.4 0.2 -1.5 0.1 -0.5 -0.5 -0.2 -0.3 -0.5 -1.2 -0.0 -0.5 -0.1 -0.8
Qualifications: NVQ or HND or HNC or equivalent 1.6 1.9 4.6 0.6 -1.7 -1.7 -1.1 -1.5 -0.8 -1.3 -1.5 -1.6 -1.6 -0.0 -1.4 -0.9 -1.4 -1.6 -1.4 -2.0 -1.0 -0.2 -2.1 -0.6 1.9 -1.2 -2.0 -1.1 -1.8 -0.7 -0.4 -1.6 -1.3 1.1 -1.4
Commuting to job workplace: Car/motor vehicle 0.2 0.3 1.4 -0.7 -0.6 -0.8 0.4 -0.4 0.7 0.2 -1.2 -0.4 0.0 -0.1 -0.3 0.2 -0.4 0.1 -0.2 -0.7 0.2 0.3 -1.0 -0.1 0.6 -0.1 -0.8 -0.7 -0.6 0.3 0.8 0.1 -0.3 0.2 0.2
Illness, injury, bereavement, stress in last 2 years 0.8 1.0 3.1 -1.0 -0.7 -1.0 -1.3 -0.7 -0.2 -1.2 -1.0 -0.6 -1.3 -0.6 -1.1 1.1 -1.0 -1.8 -0.7 -0.7 -0.9 -0.8 -0.6 -0.9 1.1 -1.2 -1.2 -1.0 -0.9 -1.3 -0.6 -1.4 -1.2 -1.1 -0.7
Medication: Aspirin 6.2 8.1 15.3 0.5 3.4 3.5 2.4 3.3 2.0 3.0 3.3 3.5 2.8 1.7 3.6 1.0 3.2 3.9 3.1 3.5 2.5 1.8 2.6 2.2 -3.1 3.5 3.4 3.1 3.7 2.5 2.0 2.9 3.1 0.3 2.7
Supplements: Vitamin C 1.0 1.2 3.9 0.9 1.3 1.4 0.2 1.0 0.5 1.7 1.1 1.4 0.7 -0.1 1.0 0.6 1.0 0.6 1.0 1.7 0.7 -0.1 2.0 1.3 -1.8 0.7 1.5 1.4 1.2 0.4 0.3 1.3 0.9 -0.8 1.3
Knee pain experienced in last month 1.7 2.7 5.3 -0.2 1.7 1.9 1.6 2.1 1.1 1.6 1.5 2.2 1.6 1.3 2.3 1.1 1.7 1.9 1.7 1.8 1.6 1.3 2.0 1.4 -1.2 2.0 1.4 1.7 1.7 1.7 1.2 1.0 1.7 2.3 1.6
Hypertension (Self-reported) 2.3 6.5 13.8 -1.4 2.0 2.0 3.6 2.7 2.7 1.9 1.8 2.5 2.6 1.9 3.3 0.3 2.6 3.7 2.6 2.0 3.4 3.4 1.8 2.2 -1.2 3.0 2.3 1.3 2.0 3.2 3.3 2.0 2.6 3.6 2.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.7 1.6 0.4 0.9 0.7 -0.6 0.8 0.3 1.1 0.9 0.9 0.5 0.9 0.6 1.0 1.1 0.8 0.7 1.0 0.6 1.3 0.8 0.9 -1.0 0.7 0.9 1.2 1.1 0.5 0.7 0.2 0.6 1.1 0.8
Illnesses of father: Heart disease 0.4 0.5 2.2 -1.0 0.4 0.0 0.6 0.6 1.2 0.3 0.0 0.5 0.1 0.7 0.6 0.7 0.4 0.4 0.6 -0.0 1.1 1.4 -0.0 0.8 0.6 0.6 0.1 0.4 0.2 0.9 1.5 0.3 0.5 1.5 0.8
Illnesses of siblings: Diabetes 0.1 0.1 0.4 -0.4 -0.7 -0.1 0.3 0.2 0.0 -0.4 0.0 0.2 -0.4 0.6 0.3 0.1 -0.2 0.1 -0.1 -0.1 -0.3 0.3 -0.1 -0.2 0.5 0.2 -0.3 -0.2 0.2 0.2 0.2 0.2 0.0 0.6 -0.1
Smoking status: Previous 0.3 0.4 2.5 -0.9 -0.1 -0.3 1.1 0.6 1.0 0.4 -0.5 0.6 0.7 -0.3 0.6 0.5 -0.0 0.8 0.4 0.1 0.8 1.6 0.5 0.1 0.9 1.0 -0.4 -0.4 0.0 0.6 1.0 0.1 0.2 0.6 0.3
Forced expiratory volume in 1-second (FEV1), predicted 1.3 2.8 9.2 -0.8 2.4 1.9 -0.4 1.7 1.6 0.7 1.6 1.4 1.6 3.0 1.4 1.7 1.9 1.3 1.8 1.0 2.0 0.9 0.8 2.3 -1.6 1.6 2.1 1.6 1.9 1.6 1.6 1.7 1.8 1.1 2.0
Whole body fat-free mass 1.1 6.0 11.0 -0.4 3.3 2.9 1.4 2.7 1.8 2.1 2.5 2.5 3.0 2.1 2.5 1.3 3.0 3.0 2.8 2.5 2.9 1.8 2.2 2.8 -3.2 2.3 3.0 2.5 2.7 2.3 1.8 2.1 2.8 1.3 2.5
Leg fat-free mass (right) 1.3 7.1 12.2 -0.2 3.4 3.1 1.5 2.9 1.8 1.9 2.8 2.8 3.2 2.6 2.7 1.5 3.3 3.1 3.0 2.8 3.0 2.1 2.6 3.0 -3.5 2.5 3.2 2.8 3.0 2.5 2.0 2.2 3.0 1.7 2.8
Arm fat percentage (left) 0.9 3.7 9.2 -1.6 1.7 1.2 1.3 2.0 2.1 1.5 0.9 2.0 2.2 2.4 1.9 2.0 1.8 1.8 1.9 1.5 2.4 2.2 1.7 2.4 -1.0 2.0 1.4 1.5 1.2 2.3 2.6 1.4 1.7 3.0 2.6
Average weekly red wine intake 1.9 2.8 7.2 1.0 2.7 2.3 0.3 1.6 1.0 2.4 1.9 1.6 1.9 0.8 1.3 0.7 2.0 1.1 1.9 1.8 1.4 -0.1 2.3 1.1 -2.6 1.3 2.1 2.1 1.9 1.0 0.7 1.7 1.8 -1.5 1.4
Handedness (chirality/laterality): Left-handed 0.5 0.6 2.1 -0.9 -1.2 -1.0 1.1 -0.4 -0.0 -0.5 -1.1 -0.6 -0.2 -1.1 -0.4 -0.3 -0.9 -0.5 -0.7 -0.6 -0.3 0.5 0.1 -0.7 0.8 -0.2 -0.7 -1.4 -1.0 -0.5 -0.3 -0.1 -0.5 -1.4 -0.8
Mood swings 0.2 0.4 2.4 -0.2 -0.9 -0.5 0.9 -0.6 -0.4 -1.6 0.1 -0.6 -0.3 -0.4 -0.4 -0.4 -0.6 -0.1 -0.6 -0.2 -0.2 -0.8 -0.8 -1.1 0.2 -0.4 -0.5 -1.0 -0.4 -0.4 -0.3 -0.6 -0.6 0.2 -0.3
Loneliness, isolation 2.1 2.9 13.1 3.6 -1.4 -0.7 -1.3 -1.6 -3.0 -0.8 0.1 -1.1 -1.7 -2.1 -1.3 -2.1 -0.9 -1.9 -1.9 0.0 -2.2 -2.5 -0.9 -1.8 -0.9 -1.6 -0.9 0.2 -0.2 -2.1 -2.6 -1.3 -1.4 -1.4 -1.9
Long-standing illness, disability or infirmity 0.9 1.3 4.1 -0.5 0.2 1.1 1.5 1.5 0.6 1.0 1.0 1.8 1.0 1.1 2.0 -0.3 1.0 1.3 0.9 1.4 0.9 1.1 0.5 0.9 -0.4 1.5 0.9 0.9 1.2 1.3 0.7 1.8 1.3 1.4 1.0
Ever had bowel cancer screening 0.7 0.8 3.9 1.6 0.1 0.9 -0.4 0.2 -1.1 0.4 1.4 0.7 -0.0 -0.7 0.3 -0.3 0.3 0.3 -0.0 1.8 -0.7 0.2 1.2 0.2 -1.8 -0.0 1.0 0.8 1.1 -0.7 -1.1 0.9 0.2 -2.0 0.3
Diabetes diagnosed by doctor 2.3 3.8 8.4 -2.2 2.3 1.4 1.5 2.3 2.9 1.4 1.0 2.0 1.8 2.9 2.1 2.3 1.8 1.6 2.4 0.6 2.7 1.5 0.6 2.0 0.2 2.2 1.4 1.2 1.3 2.5 2.8 1.5 2.1 2.4 2.0
Ever had stillbirth, spontaneous miscarriage or termination 0.0 0.1 0.2 -0.0 -0.0 -0.2 0.2 0.1 0.0 0.2 -0.2 0.3 -0.1 -0.5 0.2 0.4 -0.2 0.1 -0.2 0.3 -0.2 0.0 -0.5 0.0 0.3 0.1 -0.4 0.3 -0.1 -0.0 0.0 -0.2 -0.2 0.4 0.0
Friendships satisfaction 6.3 7.8 12.2 1.8 -2.7 -2.8 -3.1 -3.1 -2.5 -2.3 -2.6 -3.0 -3.2 -2.2 -3.3 -1.1 -3.0 -3.5 -2.9 -2.9 -2.9 -2.9 -2.9 -2.8 2.3 -3.0 -2.7 -2.7 -2.7 -3.1 -2.7 -3.5 -3.4 -1.4 -2.8
Qualifications: nursing, teaching 1.5 2.4 5.9 0.4 2.0 1.9 0.6 1.5 0.8 2.4 2.1 1.5 1.1 1.0 1.3 0.9 1.6 1.1 1.5 2.0 0.8 -0.3 1.9 1.1 -1.7 1.6 2.0 2.2 2.4 1.1 0.8 2.1 1.7 -0.3 1.5
Commuting to job workplace: Walk 1.0 1.1 3.8 -1.1 1.1 1.0 1.0 0.9 1.4 0.2 1.1 0.5 0.8 0.5 0.5 1.6 1.2 1.0 1.4 0.4 1.5 1.0 1.2 0.6 0.1 0.7 1.2 0.5 0.5 1.2 1.4 0.2 1.1 1.9 1.1
Eye problems/disorders: Cataract 0.2 0.3 1.5 0.5 0.2 0.6 -1.2 0.4 0.1 1.0 0.6 0.7 0.1 0.9 0.4 0.5 0.3 0.3 0.3 0.6 -0.2 -0.0 0.1 0.7 -0.5 0.2 0.4 0.7 0.8 0.0 0.2 0.6 0.4 -0.3 0.5
Mouth/teeth dental problems: Mouth ulcers 2.9 4.6 6.9 0.9 -2.4 -2.2 -1.3 -2.4 -2.4 -2.6 -2.3 -2.3 -1.8 -1.8 -2.3 -1.8 -2.5 -2.5 -2.5 -2.1 -2.3 -1.6 -1.2 -2.2 1.4 -2.4 -2.4 -2.5 -2.4 -2.3 -2.5 -2.3 -2.5 -1.1 -2.1
Medication for cholesterol 4.1 6.2 13.8 -0.1 -2.3 -2.6 -2.4 -2.8 -1.6 -1.5 -2.8 -2.9 -2.7 -2.1 -3.1 -0.5 -2.8 -3.7 -2.4 -2.9 -2.5 -3.4 -1.6 -2.0 2.6 -3.1 -2.7 -2.1 -2.9 -2.5 -2.1 -2.0 -2.5 -2.5 -2.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.8 3.2 1.4 0.6 0.9 0.2 0.6 -0.4 0.3 0.9 1.0 1.0 0.2 0.8 -1.0 0.7 1.5 0.4 1.3 -0.2 0.5 0.1 0.6 -1.8 0.8 1.2 0.5 1.0 -0.1 -0.5 0.8 0.5 -1.7 0.1
Back pain experienced in last month 0.2 0.3 5.8 0.7 0.1 0.2 -0.2 0.1 -0.1 -0.3 0.2 0.2 0.1 1.0 0.4 0.1 0.2 0.3 0.1 -0.1 0.6 -0.3 -1.1 0.0 -0.3 -0.1 0.1 0.2 0.0 0.6 0.2 -0.0 0.2 2.4 0.6
Mineral and other dietary supplements 0.8 1.1 3.5 -0.6 -1.1 -1.4 0.3 -0.8 -0.1 -1.1 -1.5 -1.2 -0.0 -0.1 -0.9 -0.2 -0.5 -0.4 -0.6 -1.9 0.1 0.7 -1.1 -0.8 1.8 -0.6 -1.3 -1.8 -1.8 0.0 0.1 -1.4 -0.6 1.8 -1.1
Breast cancer (self-reported) 0.1 0.1 1.0 0.3 0.1 0.1 0.1 -0.2 -0.1 0.2 -0.1 -0.1 0.4 -0.6 -0.1 -0.3 0.0 -0.2 0.1 -0.0 -0.2 0.1 0.5 -0.3 -0.1 -0.1 0.1 -0.0 -0.2 -0.1 -0.3 0.4 0.2 -1.0 -0.4
Asthma (self-reported) 1.4 2.8 4.9 -0.9 1.5 1.8 2.1 1.9 1.6 1.2 1.6 1.7 1.6 1.5 1.9 0.7 1.8 1.5 1.9 1.6 2.1 0.9 1.6 1.4 -1.4 2.2 2.1 1.4 1.9 1.8 1.5 2.2 2.1 0.2 1.6
Osteoporosis (self-reported) 0.6 0.8 2.5 1.2 -0.9 -0.5 -0.7 -0.7 -1.0 -0.7 -0.4 -0.6 -0.5 -1.1 -0.8 -0.5 -0.8 -0.2 -0.8 -0.5 -0.6 -0.7 -0.4 -1.6 -0.2 -0.6 -0.7 -1.4 -0.3 -1.2 -1.3 -1.2 -1.0 -1.6 -1.0
Osteoarthritis (self-reported) 0.5 0.7 4.3 2.1 0.1 0.6 -0.5 0.4 -1.0 0.8 0.6 0.7 -0.2 -1.1 0.4 -0.7 0.2 0.6 -0.1 1.1 -0.4 0.3 0.5 -1.1 -1.5 0.5 0.9 -0.0 1.1 -0.7 -1.1 0.0 0.1 -1.7 -0.2
Medication: Aspirin 6.6 8.6 16.9 0.0 3.5 3.4 2.5 3.4 2.4 2.9 3.1 3.6 3.0 2.1 3.6 1.5 3.2 4.1 3.3 3.4 2.9 2.0 2.5 2.4 -2.9 3.7 3.4 2.8 3.5 2.8 2.4 2.9 3.1 1.0 2.9
Medication: Gliclazide 1.7 1.9 4.0 -1.7 1.5 1.1 1.4 1.6 2.0 0.8 0.8 1.4 1.7 1.0 1.3 1.7 1.3 1.6 1.8 0.8 1.6 1.9 0.4 1.6 -0.3 1.4 1.3 0.9 1.0 1.5 1.7 1.6 1.6 0.0 1.3
Illnesses of father: None of the above (group 1) 0.6 0.7 4.2 1.4 -0.4 -0.1 -0.4 -0.7 -1.5 -0.7 0.1 -0.7 -0.3 -1.0 -0.9 -1.4 -0.2 -0.2 -0.7 0.3 -1.2 -1.1 0.2 -0.5 -1.1 -0.7 0.0 -0.1 -0.2 -1.0 -1.7 -0.1 -0.4 -2.0 -0.9
Smoking status: Current 0.3 0.5 1.1 0.9 0.9 1.0 0.9 0.6 0.1 0.4 1.0 0.7 0.8 0.2 0.7 -0.4 0.9 0.7 0.7 0.8 0.6 -0.0 1.0 0.9 -1.0 0.7 0.7 1.1 0.9 0.6 0.4 0.3 0.7 0.2 0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.2 2.5 -0.6 0.1 -0.1 -1.0 -0.1 0.4 0.2 -0.5 -0.3 -0.2 0.0 -0.6 1.6 -0.1 -0.7 0.1 -0.1 -0.0 0.3 -0.2 0.7 -0.0 -0.6 0.2 -0.1 -0.3 -0.2 0.1 0.1 -0.1 -0.8 0.2
Whole body water mass 1.1 6.0 10.9 -0.4 3.3 2.8 1.3 2.7 1.9 2.1 2.4 2.5 3.0 2.2 2.4 1.5 3.0 3.0 2.8 2.4 2.9 1.8 2.2 2.8 -3.1 2.3 3.0 2.5 2.7 2.3 1.9 2.1 2.8 1.4 2.6
Leg predicted mass (right) 1.3 7.0 12.0 -0.3 3.4 3.1 1.4 2.9 1.8 1.9 2.8 2.7 3.2 2.7 2.7 1.5 3.3 3.1 2.9 2.8 3.0 2.1 2.5 3.0 -3.5 2.5 3.2 2.8 3.0 2.5 2.0 2.2 2.9 1.7 2.8
Arm fat mass (left) 1.0 4.0 9.1 -1.4 2.1 1.5 1.3 2.1 2.0 1.6 1.2 2.0 2.4 2.5 2.1 1.7 2.0 2.0 2.1 1.6 2.6 2.0 1.7 2.5 -1.5 1.9 1.7 1.8 1.4 2.4 2.5 1.6 1.9 3.0 2.6
Number of self-reported non-cancer illnesses 2.0 3.4 8.4 -0.3 1.3 1.5 2.0 2.1 1.9 1.8 1.3 2.1 1.9 1.7 2.4 0.9 1.7 2.8 1.8 1.4 2.5 2.9 1.1 1.4 -0.7 2.4 1.4 0.8 1.4 2.1 2.3 0.9 1.6 2.9 2.2
Average weekly champagne plus white wine intake 1.3 1.8 3.1 -0.8 1.4 1.2 1.4 1.5 1.8 1.7 1.1 1.4 1.7 1.3 1.5 1.3 1.2 1.5 1.5 1.0 1.7 0.3 0.5 1.0 -0.6 1.6 1.6 0.6 1.1 1.6 1.7 1.1 1.3 1.3 1.7
Miserableness 0.1 0.1 1.1 -0.4 -0.4 0.4 0.2 -0.1 0.1 -0.6 0.4 -0.2 -0.1 -0.3 -0.4 1.1 0.1 0.1 0.2 0.3 -0.0 0.9 0.2 -0.0 -0.5 -0.4 0.1 -0.2 0.2 -0.2 -0.1 -0.1 0.0 -0.4 0.4
Guilty feelings 0.3 0.4 2.1 1.0 0.1 0.5 0.4 0.1 -0.6 0.1 1.2 0.3 -0.0 -1.0 0.1 -0.2 0.5 -0.4 0.0 1.5 -0.3 -0.5 0.9 0.2 -1.3 -0.1 0.5 0.9 0.9 -0.4 -0.4 -0.1 0.1 -0.3 0.2
Wears glasses or contact lenses 0.2 0.2 0.9 -0.6 0.6 0.1 0.3 0.5 0.7 0.3 0.2 0.5 0.6 0.3 0.4 0.3 0.2 0.3 0.3 0.6 -0.0 0.4 0.7 0.8 -0.1 0.8 0.2 0.2 0.4 0.3 0.9 0.1 -0.0 0.4 1.0
Ever taken oral contraceptive pill 0.5 0.6 2.7 -0.0 0.8 0.5 1.0 0.7 0.4 1.6 0.5 0.8 0.8 0.2 1.0 -0.7 0.5 0.7 0.4 0.5 0.4 -0.3 1.3 1.1 -0.5 1.1 0.4 1.2 0.9 0.7 0.5 0.8 0.6 0.2 0.3
Hearing aid user 0.7 0.8 2.4 -0.3 -1.3 -1.1 -0.6 -0.4 -0.4 -1.2 -1.4 -0.2 -1.2 -0.8 -0.4 -0.4 -1.2 -0.8 -0.8 -0.8 -0.7 0.7 -1.1 -0.8 1.1 -0.3 -1.4 -1.5 -1.1 -0.8 -0.6 -0.7 -1.0 -0.8 -0.9
Mother’s age at death 0.3 0.4 1.3 -0.0 0.7 0.6 1.0 0.5 0.2 0.6 0.6 0.6 0.7 -0.6 0.5 0.4 0.4 0.8 0.5 1.1 0.3 -0.3 0.6 0.2 -0.9 0.6 0.8 0.8 0.8 0.4 0.2 1.0 0.6 -0.4 0.9
Financial situation satisfaction 4.6 5.7 8.4 2.1 -2.9 -2.6 -2.4 -2.7 -2.3 -1.1 -2.6 -2.6 -2.7 -2.6 -2.5 -1.8 -2.6 -2.3 -2.7 -2.8 -2.2 -0.7 -2.1 -1.3 2.5 -2.6 -2.9 -2.1 -2.7 -2.4 -2.2 -2.8 -2.7 -0.5 -2.8
Tinnitus: Yes, now most or all of the time 0.9 1.1 6.6 -0.8 0.8 0.6 0.7 0.9 1.2 0.1 0.5 1.0 1.1 1.4 0.9 1.5 0.8 0.3 1.0 0.5 1.3 0.4 0.5 1.2 0.0 1.0 0.0 1.4 0.5 1.4 1.7 0.4 0.8 2.6 1.1
Commuting to job workplace: Public transport 1.4 1.6 3.7 -0.1 1.3 1.6 1.6 1.4 0.3 0.8 1.9 1.4 1.5 0.1 1.4 -0.1 1.3 1.2 1.2 1.7 1.0 0.9 1.8 1.5 -1.6 1.2 1.7 1.6 1.5 0.8 0.1 1.5 1.4 -0.7 0.7
Eye problems/disorders: Glaucoma 1.5 1.8 5.2 0.6 -1.0 -1.5 -2.3 -1.4 -1.0 -0.6 -1.0 -1.3 -1.4 -0.4 -1.3 -0.6 -1.5 -1.2 -1.4 -1.7 -1.4 -1.7 -1.7 -1.8 1.3 -1.4 -1.6 -1.0 -1.0 -1.4 -0.9 -1.9 -1.7 0.0 -1.0
Medication: Blood pressure 3.6 6.9 14.9 -1.1 2.2 2.7 3.9 2.7 2.3 1.4 2.5 2.5 2.9 1.9 3.0 0.9 3.1 3.5 2.9 2.6 3.1 3.1 2.0 2.1 -2.2 2.8 2.8 1.9 2.3 3.1 2.7 2.4 2.9 3.2 2.9
Pain type(s) experienced in last month: Hip pain 0.3 0.4 1.6 1.3 0.3 0.7 0.3 0.5 -0.6 0.6 0.8 0.7 0.2 -0.1 0.8 -0.9 0.5 0.4 0.1 0.7 -0.0 -0.8 0.6 -0.4 -0.8 0.7 0.3 1.1 1.0 0.2 -0.4 0.5 0.6 0.3 -0.2
Supplements: Fish oil (including cod liver oil) 0.4 0.5 2.9 1.1 0.1 0.5 -0.9 -0.1 -0.8 0.4 0.7 0.3 -0.8 -0.6 0.1 -0.5 -0.3 -0.5 -0.3 0.9 -0.9 -0.9 0.5 -0.2 -0.9 -0.2 0.2 1.1 0.8 -0.8 -0.8 0.5 -0.2 -1.7 0.1
High cholesterol (Self-reported) 2.0 3.6 7.1 -1.8 1.5 1.2 1.7 2.1 2.2 2.2 0.9 2.2 1.8 2.6 2.5 1.0 1.4 2.4 1.8 1.0 2.2 2.7 1.8 1.8 -0.1 2.3 1.2 1.1 1.2 2.3 2.3 1.9 1.7 2.3 2.1
Medication: Bendroflumethiazide 1.4 2.1 4.8 -2.1 0.9 0.8 2.2 1.5 2.0 0.8 0.7 1.3 1.7 1.4 1.7 1.1 1.0 1.8 1.5 0.9 2.1 2.2 0.4 1.0 -0.1 1.6 1.1 0.5 0.8 1.8 2.0 1.1 1.2 1.7 1.7
Medication: Paracetamol 0.1 0.2 1.5 0.6 0.3 0.2 -0.4 -0.2 -0.1 -0.9 0.5 -0.1 0.7 1.2 0.1 -0.2 -0.1 0.2 -0.1 -0.2 0.3 -0.1 -0.3 -0.3 -0.7 -0.1 0.1 -0.2 0.1 -0.1 0.1 -0.6 -0.3 0.5 0.6
Medication: Lisinopril 1.1 1.4 3.2 0.3 1.5 1.0 0.8 1.4 1.1 0.7 1.2 1.5 0.9 1.0 1.6 0.5 1.2 1.8 1.2 1.3 1.3 1.5 1.1 0.9 -0.8 1.2 1.1 1.2 1.2 1.0 1.3 0.9 1.1 1.1 1.5
Medication: Atorvastatin 3.9 4.8 9.1 -1.6 2.1 1.9 2.5 2.3 2.4 2.2 1.4 2.2 2.1 2.0 2.5 1.3 2.3 2.2 2.5 1.6 2.3 2.8 1.8 3.0 -1.1 2.5 2.0 1.8 1.6 2.9 2.6 2.5 2.6 2.2 2.2
Illnesses of father: High blood pressure 0.1 0.2 0.9 0.8 -0.3 -0.1 0.2 -0.3 -0.2 0.0 -0.3 -0.3 0.6 -0.4 -0.0 -0.7 -0.1 0.2 -0.2 -0.5 0.1 0.1 -0.5 -1.0 -0.2 -0.2 -0.4 -0.6 -0.4 -0.1 -0.2 -0.6 -0.2 0.4 -0.3
Alcohol drinker status: Never 0.5 0.6 3.2 1.3 -0.6 -0.0 -0.1 -0.7 -1.6 -0.6 0.2 -0.7 -0.0 -0.8 -0.3 -1.8 -0.3 -0.1 -0.8 -0.1 -0.7 0.2 0.7 -1.0 -1.3 -0.5 -0.1 -0.5 0.0 -0.6 -1.5 -0.3 -0.4 -0.2 -0.4
Ever smoked 2.1 3.7 6.4 -0.7 2.0 1.7 2.2 2.2 2.1 1.6 1.6 2.1 2.1 1.2 2.1 1.6 2.1 2.0 2.1 1.7 2.3 1.7 2.5 2.1 -0.8 2.4 1.6 2.0 1.9 2.2 2.3 1.6 2.2 1.7 1.7
Basal metabolic rate 1.3 7.2 12.1 -0.7 3.5 3.0 1.6 2.9 2.2 2.3 2.5 2.7 3.3 2.5 2.7 1.6 3.2 3.1 3.0 2.6 3.2 2.0 2.4 3.1 -3.2 2.6 3.2 2.7 2.8 2.6 2.2 2.4 3.0 1.8 3.0
Leg fat percentage (left) 0.8 2.9 10.2 -2.1 1.3 0.6 1.2 1.7 2.3 1.4 0.3 1.6 2.0 2.5 1.7 1.9 1.3 1.3 1.7 0.7 2.4 1.9 0.8 2.0 -0.2 1.8 0.8 0.9 0.5 2.2 2.7 0.9 1.3 3.2 2.2
Arm fat-free mass (left) 0.8 4.0 7.2 -0.7 2.7 2.1 1.1 2.2 1.8 1.9 1.6 1.9 2.5 2.1 2.0 1.3 2.4 2.3 2.3 1.6 2.7 1.5 1.4 2.3 -2.3 1.9 2.4 1.9 1.9 2.1 1.8 1.6 2.2 1.7 2.2
Number of operations (self-reported) 0.1 0.2 0.9 0.0 0.2 -0.5 -0.1 -0.3 0.4 0.3 -0.5 -0.4 -0.5 -0.3 -0.3 0.1 -0.4 -0.0 -0.1 -0.4 -0.0 0.7 -0.3 0.4 0.6 -0.3 -0.4 -0.4 -0.6 0.1 0.6 -0.3 -0.3 0.9 0.5
Average weekly beer plus cider intake 2.8 4.0 6.6 -0.6 2.0 2.1 2.2 1.9 1.5 2.1 1.8 1.9 1.9 1.7 2.2 0.2 2.5 2.1 2.1 2.0 1.8 1.7 1.9 2.6 -1.9 2.1 2.3 2.3 2.3 2.4 1.9 2.2 2.4 2.0 2.0
Irritability 0.3 0.5 2.6 1.3 0.3 0.9 0.4 0.1 -0.8 -0.2 1.5 0.3 0.4 0.1 0.5 -0.9 0.6 0.5 0.1 1.1 0.0 -0.9 0.5 -0.5 -1.6 -0.2 1.0 0.5 0.7 -0.3 -0.8 0.3 0.3 -0.5 0.3
Risk taking 0.1 0.1 0.4 0.6 -0.2 -0.4 -0.3 -0.5 -0.2 -0.3 -0.3 -0.6 -0.3 0.1 -0.4 -0.5 -0.2 -0.6 -0.4 -0.6 0.3 0.1 -0.2 0.6 0.3 -0.6 -0.3 0.0 -0.5 -0.1 -0.0 -0.2 -0.2 0.3 -0.3
Ever had prostate specific antigen (PSA) test 2.8 3.2 8.3 1.9 -1.4 -1.5 -2.7 -2.1 -2.4 -0.8 -1.1 -2.0 -2.3 -1.5 -2.0 -1.7 -1.8 -1.6 -2.1 -1.3 -2.9 -1.7 -1.0 -1.9 0.9 -2.1 -1.5 -1.0 -1.1 -2.1 -2.1 -1.5 -2.0 -1.0 -1.7
Fractured/broken bones in last 5 years 0.3 0.4 1.1 0.4 0.4 0.9 -0.0 0.6 0.4 0.9 0.8 0.7 0.5 0.8 0.5 0.4 0.7 0.3 0.7 0.6 0.4 0.1 0.5 1.0 -1.0 0.5 0.9 0.8 0.7 0.4 0.3 0.7 0.7 -0.5 0.4
Age started oral contraceptive pill 1.5 1.9 6.8 0.4 1.6 1.9 0.2 1.7 0.3 0.6 1.8 2.0 1.1 -0.2 1.4 1.5 1.7 1.5 1.4 2.6 0.7 1.0 1.3 0.8 -2.5 1.2 1.9 1.1 2.0 0.4 -0.1 0.8 1.2 -1.0 1.1
Diastolic blood pressure, automated reading 1.1 3.4 7.7 -2.0 1.9 1.1 2.8 1.8 2.1 1.4 0.6 1.3 2.7 1.6 2.1 -0.7 1.7 2.8 1.9 0.4 2.7 2.2 1.5 1.8 -1.1 2.4 1.5 0.5 1.1 2.6 2.3 1.7 2.0 1.8 1.5
Ever depressed for a whole week 3.2 4.0 9.1 0.3 2.0 2.5 1.5 1.9 1.2 2.3 2.5 1.9 2.0 1.3 2.0 0.4 2.4 1.9 2.1 2.4 1.9 1.1 3.0 2.0 -2.7 2.0 2.3 2.1 2.0 1.9 1.5 2.0 2.1 1.4 2.4
Unable to work because of sickness or disability 0.8 1.0 3.5 0.7 0.5 1.5 0.8 0.8 -0.6 0.8 1.7 1.1 0.7 0.4 1.2 -0.4 1.1 0.9 0.5 1.5 -0.0 0.7 1.3 0.7 -1.9 0.7 1.5 1.4 1.5 0.3 -0.5 1.2 1.0 -0.1 0.3
Commuting to job workplace: Cycle 0.3 0.4 4.1 -0.3 0.3 0.5 -0.5 0.4 -0.0 0.0 0.6 0.4 -0.4 -0.6 -0.1 1.6 0.1 0.1 0.3 0.5 -0.1 -0.7 0.4 -0.4 -0.4 0.1 0.6 -0.1 0.4 -0.6 -0.7 -0.2 0.1 -2.0 -0.2
Myopia 6.3 9.1 15.4 -3.9 3.0 2.6 3.5 3.2 3.9 2.1 2.6 2.8 3.6 3.4 3.0 3.2 2.9 3.2 3.5 2.0 3.5 3.0 2.4 3.1 -1.3 3.1 2.8 1.8 2.1 3.5 3.6 3.0 3.2 2.1 3.3
Vascular/heart problems diagnosed by doctor 2.4 6.7 16.6 1.8 -1.9 -1.8 -3.7 -2.7 -3.0 -1.9 -1.7 -2.4 -2.6 -2.1 -3.2 -0.8 -2.5 -3.8 -2.7 -1.6 -3.5 -3.7 -1.5 -1.9 0.6 -3.1 -2.0 -1.0 -1.9 -3.4 -3.5 -1.9 -2.5 -4.1 -2.8
Cholesterol lowering medication 4.6 6.8 10.2 -1.4 2.6 2.7 2.0 2.9 2.6 2.4 2.1 2.9 2.6 3.2 3.0 2.3 2.9 2.8 3.0 2.2 2.9 3.1 2.1 2.4 -1.6 2.9 2.6 2.1 2.5 3.0 2.7 2.5 2.9 2.9 2.8
Medication: Omeprazole (e.g. Zanprol) 0.1 0.1 0.9 0.4 -0.3 0.0 -0.2 0.3 -0.3 0.6 0.5 0.6 0.2 0.4 0.6 -0.4 -0.1 0.4 -0.2 0.4 0.1 1.0 -0.0 0.4 -0.2 0.4 0.2 0.4 0.3 -0.3 -0.3 0.3 -0.1 -0.6 0.0
Pain experienced in last month 0.4 0.7 3.9 -1.8 0.8 0.5 0.8 0.6 1.3 0.3 0.4 0.4 0.8 -0.0 0.3 1.0 0.6 0.5 0.9 0.6 0.7 2.0 1.0 1.2 -0.1 0.5 0.7 0.4 0.4 0.6 0.9 1.0 0.7 -1.2 0.6
Supplements: Calcium 0.4 0.5 2.6 1.5 0.4 0.9 0.1 0.1 -0.6 0.6 1.1 0.3 0.1 -0.6 0.2 -0.9 0.4 0.8 0.2 1.2 0.0 -0.3 0.3 0.2 -1.6 -0.0 0.8 0.8 1.1 -0.2 -0.7 0.7 0.3 -0.9 0.4
Basal cell carcinoma (self-reported) 0.1 0.2 0.8 0.7 0.0 -0.3 0.5 -0.2 -0.1 -0.2 -0.3 -0.5 0.3 -0.3 -0.2 -0.5 -0.1 0.7 -0.1 -0.4 0.6 0.4 -0.0 -0.3 0.0 0.1 0.0 -0.8 -0.3 0.2 0.1 -0.6 -0.2 0.9 -0.2
Heart attack/myocardial infarction (self-reported) 0.1 0.1 0.5 0.7 -0.0 0.3 -0.7 0.1 -0.2 0.3 0.3 0.4 0.1 0.2 0.0 0.3 0.3 0.5 0.2 0.4 -0.3 0.3 -0.6 0.2 -0.3 -0.0 0.2 0.5 0.1 -0.1 -0.2 0.1 0.1 0.1 0.2
Deep venous thrombosis (DVT) (self-reported) 0.9 1.1 4.2 -1.6 0.7 0.3 1.1 1.5 1.8 -0.0 -0.1 1.4 0.7 1.4 1.1 1.6 0.6 1.0 1.1 0.3 1.4 2.0 -0.1 0.8 0.6 1.7 0.3 -0.1 0.3 1.0 1.6 0.5 0.8 0.1 0.6
Heart disease (siblings) 0.6 0.8 2.9 -1.6 0.5 0.4 0.5 1.1 1.1 0.2 0.2 1.2 -0.1 1.1 0.9 1.7 0.5 0.8 0.8 0.6 0.4 1.6 0.1 0.7 0.6 1.0 0.2 0.6 0.7 0.9 1.2 0.8 0.8 1.0 0.9
Alcohol drinker status: Previous 0.7 0.8 2.8 1.5 -1.0 -0.0 -1.1 -0.5 -1.5 0.0 0.6 -0.1 -0.8 -1.5 -0.4 -0.2 -0.6 -0.3 -0.9 0.3 -1.2 -0.2 -0.2 -1.3 -0.4 -0.7 -0.4 -0.4 0.3 -1.6 -1.7 -1.2 -0.9 -1.6 -0.8
Pack years of smoking 0.7 1.0 2.4 -0.0 0.5 1.1 0.7 0.9 0.1 0.6 1.1 1.0 1.1 1.5 1.0 0.3 1.1 1.1 0.8 1.2 0.4 1.5 0.9 1.2 -1.4 1.0 1.0 1.1 1.2 0.9 0.5 1.1 1.1 1.2 0.9
Impedance of whole body 0.2 1.0 4.8 1.1 -1.0 -0.5 -1.3 -0.9 -1.2 0.1 -0.0 -0.5 -1.2 -1.2 -0.8 -0.2 -1.1 -1.7 -1.2 0.1 -1.8 -1.3 -0.2 -1.0 0.2 -0.7 -0.6 0.0 0.1 -1.5 -1.3 0.0 -1.0 -2.2 -0.5
Leg fat mass (left) 1.2 4.8 10.8 -1.8 2.2 1.6 1.4 2.4 2.5 1.8 1.2 2.2 2.5 2.9 2.3 2.2 2.1 2.1 2.3 1.6 2.9 2.0 1.5 2.6 -1.2 2.3 1.7 1.7 1.4 2.6 2.8 1.6 2.0 3.3 2.8
Arm predicted mass (left) 1.1 5.6 10.3 -0.8 3.2 2.6 1.4 2.6 2.1 2.2 2.0 2.3 3.0 2.5 2.4 1.5 2.8 2.8 2.8 2.0 3.1 1.6 1.8 2.8 -2.7 2.2 2.8 2.3 2.3 2.4 2.1 1.9 2.7 1.7 2.6