Hub : Genes

C17orf82

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 TCGA Bladder Urothelial Carcinoma 0.034 0.019 0.0032 0.020 0.004 0.001 NA 0.002 0.0079 0.130 0.25 NA 0.220
2 TCGA Skin Cutaneous Melanoma 0.126 0.062 0.0051 0.007 0.026 0.031 NA 0.026 0.2100 0.067 0.05 NA 0.068

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.2 0.3 0.6 -0.8 -0.1
Bipolar Disorder or Schizophrenia 1.3 3.1 5.0 -2.2 1.1
Depressed Affect (Nagel 2018) 0.1 0.3 0.5 0.7 -0.1
Depression (Nagel 2018) 0.7 1.1 1.9 -1.4 -0.5
Intelligence (Savage-Jansen 2018) 0.6 1.8 3.6 1.9 -0.1
Neuroticism (Nagel 2018) 0.0 0.1 0.2 0.4 0.1
Schizophrenia (2018) 1.7 3.5 4.9 -2.2 1.5
Schizophrenia vs Biploar Disorder 0.8 1.1 1.3 -1.1 0.9
Worry (Nagel 2018) 0.2 0.4 0.8 0.1 0.9
Alzheimer’s Disease (in mother) 2.8 3.3 6.5 2.5 -0.3
Alzheimer’s Disease (in father) 1.5 1.6 2.5 1.6 0.8
Alzheimer’s Disease (including proxy) 2.3 3.4 6.2 2.5 0.7
Crohns Disease (2017) 0.2 0.4 0.8 -0.9 -0.3
Irritable Bowel Disease (IBD) 0.3 0.6 1.2 -1.1 -0.3
Ulcerative Colitis (UC) 0.7 1.4 2.7 -1.6 0.2
Major Depression (MDD) 1.9 2.2 4.0 -0.7 -2.0
Reaction Time 0.2 0.3 0.5 -0.4 -0.7
Verbal and Numeric Reasoning (VNR) 1.4 3.4 4.9 2.2 -1.4
Breast Cancer 1.2 2.8 4.2 2.0 -1.2
Ovarian Cancer 0.2 0.2 0.4 -0.2 -0.7
Prostate Cancer 0.3 0.5 0.5 -0.7 0.7
Age at First Birth 0.2 0.3 0.4 0.4 0.7
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 1.4 1.9 3.4 1.8 -0.6
Coronary Artery Disease (CAD) 1.2 1.4 1.4 1.2 -1.2
Crohns Disease (2012) 0.0 0.0 0.0 0.0 0.0
Mean Putamen Volume 0.5 0.6 0.6 0.8 0.7
Fasting Glucose 0.4 0.5 0.8 0.4 -0.9
HbA1C 3.4 3.8 4.2 -2.1 1.8
HDL Cholesterol 0.5 0.9 1.7 1.3 -0.2
LDL Cholesterol 0.0 0.1 0.1 -0.2 -0.3
Lupus 0.3 0.5 0.8 0.4 -0.9
Neuroticism (2016) 0.0 0.0 0.1 -0.2 0.1
Primary Biliary Cirrhosis 0.4 0.6 1.1 -1.0 -0.4
Rheumatoid Arthritis 0.3 0.5 0.8 -0.9 0.4
Schizophrenia (2014) 1.3 2.9 5.3 -2.3 0.6
Triglycerides 0.7 1.1 2.2 -0.3 1.5
Type 2 Diabetes (T2D) (2012) 0.6 0.6 0.8 -0.9 0.7
Ulcerative Colitis 1.3 1.8 1.9 -1.4 1.3
Blood Eosinophil Count 0.2 1.4 2.5 -0.5 1.6
Blood Platelet Count 0.3 3.4 5.4 2.3 -1.2
Blood Red Count 3.9 37.7 48.7 -7.0 5.2
Blood White Count 0.1 0.7 0.8 -0.9 0.7
Heel T-Score 0.9 7.5 10.4 -3.2 2.1
BMI 2.2 12.6 19.6 4.4 -2.4
Height 26.5 511.4 835.2 -28.9 13.7
Waist Hip Ratio (WHR) 20.0 89.9 125.4 -11.2 7.4
Systolic Blood Pressure 8.1 40.5 63.8 8.0 -4.2
Smoking Status 0.1 0.2 0.3 0.1 0.6
Allergy or Eczema 0.1 0.2 0.3 -0.5 0.3
Cardiovascular Disease 6.4 21.1 33.6 5.8 -2.9
Hypothyroidism (self reported) 0.2 0.5 0.9 0.9 -0.3
Respiratory disease 0.1 0.1 0.2 -0.2 0.5
Type 2 Diabetes (T2D) (2018) 1.0 1.8 2.1 -1.4 1.2
Lung FEV1/FVC ratio 0.8 4.1 4.3 -2.0 2.1
Lung FVC 9.1 46.6 84.8 9.2 -2.9
Neuroticism 0.1 0.1 0.3 -0.1 0.5
Chronotype (morning person) 0.1 0.1 0.2 -0.5 -0.0
Hair Pigment 0.0 1.0 1.4 1.2 -0.8
Tanning 0.2 2.2 3.2 -1.1 1.8
Hand grip strength (left) 3.3 8.6 9.4 -3.1 2.8
Number of treatments/medications taken 0.1 0.1 0.2 -0.1 -0.5
Average weekly spirits intake 3.7 4.6 6.8 -2.6 1.6
Sensitivity / hurt feelings 0.2 0.3 0.5 -0.2 0.7
Frequency of depressed mood in last 2 weeks 0.3 0.4 0.8 -0.9 0.1
Hearing difficulty/problems: Yes 0.3 0.4 0.8 -0.9 0.1
Relative age of first facial hair 0.7 1.4 2.3 -1.5 0.6
Other serious medical condition/disability diagnosed by doctor 0.6 0.7 0.8 -0.9 0.8
Ever used hormone-replacement therapy (HRT) 2.0 2.6 3.2 -1.8 1.4
Ever had hysterectomy (womb removed) 0.3 0.3 0.7 -0.0 0.8
Systolic blood pressure, automated reading 8.3 24.0 38.3 6.2 -3.1
Eye problems/disorders: Diabetes related eye disease 4.7 5.1 7.8 1.6 -2.8
Angina 2.7 3.6 5.8 2.4 -1.2
Medication for hormone replacement therapy 3.4 3.8 4.1 -1.9 2.0
Vitamin and mineral supplements 0.0 0.0 0.1 0.2 -0.2
Supplements: Zinc 1.1 1.2 1.5 1.2 -0.9
Medication: Co-codamol 0.4 0.5 0.8 -0.9 -0.3
Medication: Metformin 0.4 0.6 1.1 -1.0 0.2
Diabetes (father) 2.0 2.4 4.5 0.6 -2.1
Diabetes (mother) 0.0 0.0 0.0 0.1 -0.0
Severe depression (siblings) 0.9 1.0 1.7 -0.6 1.3
Pack years adult smoking proportion 0.4 0.6 0.8 -0.6 -0.9
Impedance of leg (right) 0.7 3.4 3.9 -2.0 1.7
Leg fat-free mass (left) 5.7 30.1 53.3 -7.3 2.6
Trunk fat percentage 1.1 4.6 5.9 2.4 -1.8
Hand grip strength (right) 3.0 8.0 8.1 -2.8 2.8
Townsend deprivation index at recruitment 1.3 1.8 3.5 0.1 -1.9
Current tobacco smoking 0.3 0.4 0.7 -0.4 0.9
Average weekly fortified wine intake 0.0 0.0 0.1 0.1 -0.2
Maternal smoking around birth 0.1 0.1 0.2 0.5 0.0
Fed-up feelings 0.0 0.0 0.0 0.2 0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 1.1 1.5 2.6 -1.6 0.6
Relative age voice broke 3.2 4.8 6.1 -2.5 1.9
Taking other prescription medications 1.0 1.5 2.3 -1.5 0.9
Age when periods started (menarche) 0.4 0.8 1.4 0.6 -1.2
Bilateral oophorectomy (both ovaries removed) 0.3 0.4 0.6 -0.7 -0.4
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.6 0.8 -0.6 0.9
Tinnitus: Yes, but not now, but have in the past 0.1 0.1 0.1 0.4 0.0
Qualifications: CSEs or equivalent 0.5 0.7 0.8 0.9 -0.8
Serious illness, injury or assault to yourself 3.0 3.7 4.0 -1.8 2.0
High blood pressure 4.0 11.2 18.6 4.3 -1.9
Hayfever, allergic rhinitis or eczema 0.0 0.1 0.1 -0.4 0.1
Multivitamins +/- minerals 0.3 0.3 0.6 0.8 0.3
Stomach or abdominal pain in last month 1.5 1.8 1.9 -1.3 1.4
Supplements: Glucosamine 0.6 0.8 0.9 0.9 -0.9
Diverticular disease/diverticulitis (self-reported) 2.2 2.6 5.1 -0.2 2.3
Medication: Atenolol 5.7 7.1 10.1 2.0 -3.2
Medication: Levothyroxine sodium 0.3 0.5 0.9 -0.0 1.0
Sitting height 0.9 6.5 6.7 -2.5 2.6
Chronic bronchitis/emphysema (father) 1.3 1.6 2.8 -1.7 0.6
High blood pressure (mother) 2.5 3.5 5.1 2.3 -1.4
Body mass index (BMI) 2.5 10.6 15.9 4.0 -2.3
Impedance of leg (left) 0.3 1.7 2.6 -0.9 1.6
Leg predicted mass (left) 5.6 29.9 52.7 -7.3 2.7
Trunk fat mass 0.1 0.4 0.7 -0.9 -0.3
Waist circumference 1.0 3.5 6.3 -2.5 0.8
Number of incorrect matches in round 0.1 0.1 0.2 0.0 -0.4
Past tobacco smoking 0.0 0.0 0.0 -0.0 0.2
Alcohol usually taken with meals 0.3 0.6 0.8 0.6 -0.9
Nervous feelings 0.4 0.8 1.5 1.2 -0.2
Frequency of tenseness / restlessness in last 2 weeks 0.6 1.0 1.8 -0.4 1.3
Hearing difficulty/problems with background noise 1.8 2.9 4.3 -2.1 1.2
Hair/balding pattern: Pattern 2 1.2 1.5 2.5 1.6 -0.7
Had menopause 0.8 1.0 1.5 -1.2 0.7
Had other major operations 0.7 0.8 1.0 1.0 -0.8
Forced vital capacity (FVC) 0.8 3.2 3.8 -2.0 1.6
Heel bone mineral density (BMD) T-score, automated (right) 0.8 1.8 2.2 -1.1 1.5
Ever unenthusiastic/disinterested for a whole week 2.0 2.4 3.5 -1.2 1.9
Qualifications: None of the above 0.3 0.7 1.2 -0.5 1.1
Financial difficulties in last 2 years 0.1 0.1 0.1 0.4 0.3
Mouth/teeth dental problems 1.7 2.6 2.7 1.6 -1.6
Heart attack 0.0 0.1 0.1 -0.1 0.3
Allergy 0.5 1.2 1.7 0.8 -1.3
Pain all over the body in last month 0.2 0.3 0.5 0.2 -0.7
Diabetes (self-reported) 0.5 0.8 1.1 -1.0 0.7
Hayfever/allergic rhinitis (self-reported) 0.5 0.6 0.6 -0.8 0.8
Medication: Ramipril 1.1 1.4 2.0 1.4 -0.9
Medication: Simvastatin 1.4 2.1 2.6 1.6 -1.2
Fluid intelligence score 1.4 3.0 3.6 1.9 -1.5
Illnesses of siblings 0.3 0.4 0.6 -0.8 0.5
Neuroticism score 0.1 0.1 0.2 0.2 0.5
Weight 2.6 12.6 23.3 -4.8 1.4
Impedance of arm (right) 0.3 1.3 1.7 1.3 -1.0
Arm fat percentage (right) 4.7 18.5 25.8 5.1 -3.4
Trunk fat-free mass 14.2 81.4 136.9 -11.7 5.1
Hip circumference 0.5 2.3 4.3 0.6 -2.1
Time employed in main current job 1.5 1.8 3.5 -1.9 0.3
Alcohol intake versus 10 years previously 2.4 3.7 4.5 -2.1 1.7
Father’s age at death 0.3 0.4 0.6 -0.4 0.8
Worrier / anxious feelings 0.2 0.5 0.7 -0.8 0.5
Frequency of tiredness / lethargy in last 2 weeks 0.1 0.1 0.2 -0.3 -0.4
Falls in the last year 0.0 0.0 0.1 -0.2 -0.2
Hair/balding pattern: Pattern 3 0.9 1.4 2.3 -1.5 0.7
Number of live births 1.2 1.7 2.0 1.4 -1.2
Forced expiratory volume in 1-second (FEV1) 0.9 2.9 2.9 -1.7 1.7
Pulse rate 0.7 1.2 1.8 -1.4 0.8
Happiness 0.5 0.6 1.2 0.1 -1.1
Noisy workplace 0.4 0.5 0.7 -0.6 0.9
Qualifications: A levels/AS levels or equivalent 0.5 1.1 2.2 0.0 1.5
Serious illness, injury or assault of a close relative in last 2 years 1.0 1.2 2.3 -0.2 1.5
Mouth/teeth dental problems: Dentures 0.2 0.4 0.6 -0.8 -0.3
Asthma 0.8 1.5 2.7 -0.6 1.6
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 1.2 1.1 -0.1
Medication: Cholesterol lowering 0.4 0.6 0.7 0.8 -0.8
Depression (self-reported) 0.5 0.6 0.8 -0.9 -0.7
Medication: Lansoprazole 1.8 2.0 3.2 -1.8 0.9
Prospective memory result 0.7 0.8 1.6 0.1 1.3
Lung cancer (father) 0.2 0.2 0.4 -0.7 0.2
Illnesses of mother 5.4 6.7 7.7 -2.8 2.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 2.0 2.8 -1.7 1.1
Pulse wave Arterial Stiffness index 2.0 2.4 4.5 -2.1 0.6
Impedance of arm (left) 0.4 1.9 2.3 1.5 -1.2
Arm fat mass (right) 0.3 1.4 1.7 1.0 -1.3
Trunk predicted mass 14.0 79.8 134.6 -11.6 5.0
Standing height 22.1 219.5 368.6 -19.2 8.4
Length of working week for main job 0.4 0.4 0.6 -0.4 -0.8
Exposure to tobacco smoke at home 0.3 0.4 0.7 0.8 -0.2
Breastfed as a baby 0.6 0.8 0.8 -0.9 -0.9
Tense / ‘highly strung’ 0.2 0.3 0.4 0.5 0.6
Seen doctor (GP) for nerves, anxiety, tension or depression 0.0 0.0 0.1 -0.2 0.1
Hair/balding pattern: Pattern 4 0.3 0.8 1.2 1.1 -0.7
Birth weight of first child 0.1 0.1 0.2 -0.3 -0.5
Peak expiratory flow (PEF) 0.3 0.6 0.9 -0.6 0.9
Pulse wave reflection index 1.2 1.5 1.7 1.3 -1.1
Ever highly irritable/argumentative for 2 days 1.5 1.8 2.4 -1.1 1.5
Loud music exposure frequency 1.7 1.9 2.2 1.2 -1.5
Qualifications: O levels/GCSEs or equivalent 0.3 0.5 0.8 0.4 0.9
Mouth/teeth dental problems: Bleeding gums 1.0 1.3 2.2 0.6 1.5
Blood clot in the leg (DVT) 1.4 1.7 3.1 -0.7 1.8
Medication: Paracetamol 0.3 0.5 0.9 1.0 -0.1
Headache pain in last month 0.1 0.2 0.4 0.6 -0.0
Medication for cholesterol, blood pressure or diabetes 1.4 2.3 2.6 -1.4 1.6
Glaucoma (self-reported) 4.4 5.2 5.3 -2.3 2.3
Gout (self-reported) 4.9 6.7 9.8 1.9 -3.1
Hypothyroidism/myxoedema (self-reported) 0.0 0.1 0.1 0.3 0.1
Medication: Amlodipine 0.5 0.7 1.3 1.2 0.0
Medication: Ventolin 100micrograms inhaler 0.1 0.1 0.3 0.5 -0.0
Birth weight 0.1 0.2 0.3 -0.4 0.6
Chronic bronchitis/emphysema (mother) 1.1 1.3 2.2 -1.5 0.5
High blood pressure (siblings) 5.8 8.4 9.3 2.8 -3.0
Forced vital capacity (FVC), Best measure 0.6 2.3 3.5 -1.9 1.1
Body fat percentage 2.0 7.9 11.1 3.3 -2.2
Leg fat percentage (right) 1.9 6.9 9.7 3.1 -2.0
Arm fat-free mass (right) 11.5 59.0 97.0 -9.8 4.6
Exposure to tobacco smoke outside home 0.3 0.4 0.8 -0.2 -0.9
Comparative body size at age 10 0.9 2.5 4.5 2.1 -0.6
Number of full brothers 0.5 0.7 0.7 -0.8 0.8
Worry too long after embarrassment 0.4 0.7 1.2 1.1 -0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 1.6 2.0 3.7 -1.9 0.6
Wheeze or whistling in the chest in last year 0.3 0.5 0.6 -0.8 -0.6
Number of children fathered 0.7 0.8 1.4 -0.4 1.2
Reason for reducing amount of alcohol drunk: Health precaution 6.0 7.0 11.2 3.3 -1.7
Age at first live birth 1.2 2.1 4.1 2.0 -0.3
Pulse wave peak to peak time 0.2 0.3 0.5 0.7 0.2
Health satisfaction 1.2 1.5 3.0 -1.7 0.2
Shortness of breath walking on level ground 0.6 0.7 1.1 -1.0 0.5
Qualifications: College or University degree 0.1 0.2 0.2 -0.3 0.5
Eye problems/disorders: None of the above 0.5 0.6 1.2 1.1 0.1
Mouth/teeth dental problems: Loose teeth 0.4 0.5 0.6 -0.8 -0.6
Emphysema/chronic bronchitis 0.7 0.8 1.1 -0.6 1.1
Medication for pain relief, constipation, heartburn 0.7 1.2 2.4 -1.5 0.2
Neck or shoulder pain in last month 2.0 2.8 4.8 -0.9 2.2
Medication: Blood pressure 2.7 4.8 5.0 2.1 -2.2
Angina (self-reported) 1.8 2.4 3.9 2.0 -1.0
Migraine (self-reported) 1.3 1.7 1.8 1.2 1.4
Medication: Ibuprofen 0.1 0.2 0.2 0.5 0.3
Medication: Allopurinol 3.8 5.0 7.1 1.7 -2.7
Medication: Omeprazole 1.1 1.3 1.5 -1.2 1.1
Medication: Seretide 50 evohaler 0.2 0.2 0.4 0.1 -0.6
Mean time to correctly identify matches 0.1 0.2 0.2 -0.5 -0.2
Heart disease (mother) 1.7 2.0 2.6 1.2 -1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.2 2.6 3.7 1.2 -1.9
Whole body fat mass 0.1 0.2 0.4 -0.3 -0.6
Leg fat mass (right) 0.0 0.1 0.1 -0.3 -0.3
Arm predicted mass (right) 11.1 56.9 93.3 -9.7 4.5
Pulse rate, automated reading 1.4 4.6 4.6 -2.1 2.1
Alcohol intake frequency. 1.6 3.6 6.2 -2.5 1.1
Comparative height size at age 10 11.9 65.4 110.2 -10.5 4.5
Number of full sisters 1.4 1.7 3.3 -0.5 1.8
Suffer from ‘nerves’ 0.2 0.3 0.5 -0.4 0.7
Overall health rating 0.7 1.6 2.9 -1.7 0.6
Chest pain or discomfort 0.1 0.1 0.2 0.2 -0.5
Had major operations 0.3 0.4 0.7 -0.9 -0.2
Age at last live birth 0.2 0.3 0.5 0.3 0.7
Family relationship satisfaction 0.0 0.0 0.0 -0.1 0.1
Leg pain on walking 0.1 0.2 0.3 -0.5 0.3
Qualifications: NVQ or HND or HNC or equivalent 2.0 2.4 2.9 1.4 -1.7
Commuting to job workplace: Car/motor vehicle 3.8 4.4 7.5 2.7 -1.1
Illness, injury, bereavement, stress in last 2 years 1.3 1.5 3.0 0.3 -1.7
Medication: Aspirin 0.1 0.1 0.1 0.3 -0.3
Supplements: Vitamin C 0.9 1.1 2.1 -1.5 0.1
Knee pain experienced in last month 1.5 2.3 4.5 -2.1 0.2
Hypertension (Self-reported) 4.3 12.0 18.4 4.3 -2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.1 0.3 -0.3
Illnesses of father: Heart disease 0.7 1.0 1.8 1.4 0.3
Illnesses of siblings: Diabetes 0.1 0.1 0.1 0.3 0.3
Smoking status: Previous 0.0 0.1 0.1 -0.3 -0.1
Forced expiratory volume in 1-second (FEV1), predicted 8.2 17.1 29.5 -5.4 2.2
Whole body fat-free mass 10.5 60.0 102.0 -10.1 4.2
Leg fat-free mass (right) 5.1 27.2 48.2 -6.9 2.5
Arm fat percentage (left) 5.1 20.2 28.2 5.3 -3.5
Average weekly red wine intake 1.5 2.1 3.1 1.1 -1.7
Handedness (chirality/laterality): Left-handed 0.7 0.8 1.6 -0.2 1.3
Mood swings 0.4 0.7 1.0 1.0 -0.6
Loneliness, isolation 2.3 3.1 3.3 -1.8 1.7
Long-standing illness, disability or infirmity 3.4 5.1 7.5 -2.7 1.7
Ever had bowel cancer screening 0.9 1.1 1.7 -1.3 0.7
Diabetes diagnosed by doctor 0.4 0.6 0.8 -0.7 0.9
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.3 0.5 -0.7 0.1
Friendships satisfaction 0.6 0.7 1.1 1.1 -0.6
Qualifications: nursing, teaching 2.8 4.4 6.5 2.5 -1.5
Commuting to job workplace: Walk 2.1 2.2 2.5 -1.6 1.4
Eye problems/disorders: Cataract 0.6 0.6 1.0 -1.0 -0.5
Mouth/teeth dental problems: Mouth ulcers 1.0 1.6 2.0 -1.1 1.4
Medication for cholesterol 0.0 0.0 0.0 -0.1 0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 1.0 -0.5 1.0
Back pain experienced in last month 0.6 0.9 1.5 -1.2 0.5
Mineral and other dietary supplements 1.1 1.4 2.3 -0.8 1.5
Breast cancer (self-reported) 0.2 0.2 0.4 -0.2 -0.6
Asthma (self-reported) 0.5 1.0 1.8 -0.4 1.4
Osteoporosis (self-reported) 0.3 0.3 0.4 -0.5 -0.6
Osteoarthritis (self-reported) 1.6 2.0 3.2 -1.8 0.9
Medication: Aspirin 0.0 0.0 0.0 0.2 -0.1
Medication: Gliclazide 0.0 0.0 0.0 -0.2 -0.2
Illnesses of father: None of the above (group 1) 0.5 0.6 0.8 -0.9 0.6
Smoking status: Current 0.3 0.4 0.8 -0.2 0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.5 3.2 6.3 2.5 0.3
Whole body water mass 10.4 59.5 102.0 -10.1 4.1
Leg predicted mass (right) 5.0 26.6 47.2 -6.9 2.5
Arm fat mass (left) 0.4 1.6 2.0 1.1 -1.4
Number of self-reported non-cancer illnesses 0.1 0.2 0.4 0.7 0.1
Average weekly champagne plus white wine intake 3.9 5.3 7.3 -1.8 2.7
Miserableness 0.2 0.3 0.5 0.7 -0.3
Guilty feelings 0.5 0.8 1.0 -1.0 0.8
Wears glasses or contact lenses 0.4 0.5 1.0 -0.3 1.0
Ever taken oral contraceptive pill 0.8 0.9 1.6 -0.5 1.3
Hearing aid user 0.6 0.6 1.2 -0.3 1.1
Mother’s age at death 1.7 2.1 3.1 -1.7 1.1
Financial situation satisfaction 0.1 0.1 0.2 0.2 -0.5
Tinnitus: Yes, now most or all of the time 0.0 0.0 0.0 -0.1 0.2
Commuting to job workplace: Public transport 0.5 0.5 0.6 -0.7 -0.8
Eye problems/disorders: Glaucoma 4.5 5.4 5.5 -2.4 2.3
Medication: Blood pressure 2.4 4.6 4.8 2.1 -2.2
Pain type(s) experienced in last month: Hip pain 0.1 0.1 0.2 0.3 0.5
Supplements: Fish oil (including cod liver oil) 0.2 0.2 0.2 -0.5 -0.5
High cholesterol (Self-reported) 2.1 3.7 5.6 2.4 -1.3
Medication: Bendroflumethiazide 5.3 8.1 8.7 2.7 -2.9
Medication: Paracetamol 0.0 0.0 0.1 0.3 0.2
Medication: Lisinopril 0.6 0.8 1.5 0.4 -1.2
Medication: Atorvastatin 0.3 0.3 0.4 0.6 0.5
Illnesses of father: High blood pressure 2.5 3.2 4.3 2.1 -1.4
Alcohol drinker status: Never 0.2 0.2 0.4 0.7 -0.2
Ever smoked 0.1 0.1 0.2 0.1 -0.5
Basal metabolic rate 8.3 46.1 79.7 -8.9 3.5
Leg fat percentage (left) 2.6 9.5 14.7 3.8 -2.1
Arm fat-free mass (left) 10.8 54.6 91.8 -9.6 4.2
Number of operations (self-reported) 0.2 0.3 0.5 -0.4 -0.7
Average weekly beer plus cider intake 1.0 1.5 3.0 -0.2 -1.7
Irritability 0.9 1.6 2.5 0.8 -1.6
Risk taking 0.0 0.1 0.1 0.3 -0.1
Ever had prostate specific antigen (PSA) test 2.0 2.3 4.4 0.6 -2.1
Fractured/broken bones in last 5 years 3.6 4.6 8.8 -3.0 -0.7
Age started oral contraceptive pill 0.5 0.7 0.9 -1.0 0.6
Diastolic blood pressure, automated reading 3.8 11.8 19.3 4.4 -2.1
Ever depressed for a whole week 2.2 2.7 3.4 -1.9 1.4
Unable to work because of sickness or disability 1.1 1.4 1.7 -1.3 -1.0
Commuting to job workplace: Cycle 0.9 1.1 1.8 -1.4 0.5
Myopia 0.6 0.9 1.2 0.8 -1.1
Vascular/heart problems diagnosed by doctor 3.9 10.7 18.0 -4.2 1.8
Cholesterol lowering medication 1.1 1.7 3.0 1.7 -0.6
Medication: Omeprazole (e.g. Zanprol) 0.7 0.9 1.1 -1.1 0.8
Pain experienced in last month 1.8 3.0 3.9 2.0 -1.5
Supplements: Calcium 0.7 0.8 1.5 0.4 -1.2
Basal cell carcinoma (self-reported) 1.1 1.3 2.6 0.2 -1.6
Heart attack/myocardial infarction (self-reported) 0.1 0.1 0.1 0.3 0.3
Deep venous thrombosis (DVT) (self-reported) 1.7 2.2 3.8 -0.8 2.0
Heart disease (siblings) 1.9 2.4 4.0 -0.9 2.0
Alcohol drinker status: Previous 0.6 0.6 0.9 -0.6 -0.9
Pack years of smoking 0.4 0.6 0.7 -0.9 -0.6
Impedance of whole body 0.0 0.1 0.2 0.3 0.5
Leg fat mass (left) 0.0 0.1 0.1 0.3 -0.4
Arm predicted mass (left) 11.0 56.0 92.4 -9.6 4.4