[Hub]/) : Traits : Cardiovascular Disease : ← →

chr19:10,283,932-12,196,190

Best TWAS P=1.6e-12 · Best GWAS P=4.03e-24 conditioned to 1.11e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous EPOR 0.11 0.04 lasso 7 0.04 3.8e-04 -7.0 -7.1 1.6e-12 0.48 0.52 0.38 TRUE
2 GTEx Artery Aorta RGL3 0.15 0.00 enet 23 0.00 2.8e-01 4.2 5.7 9.9e-09 -0.18 0.06 0.04 FALSE
3 GTEx Cells Transformed fibroblasts CARM1 0.11 0.01 lasso 4 0.00 6.9e-01 -5.3 -5.2 1.9e-07 0.35 0.29 0.04 FALSE
4 GTEx Colon Transverse SMARCA4 0.21 -0.01 enet 21 0.00 1.8e-01 -4.1 6.1 8.6e-10 -0.09 0.06 0.04 FALSE
5 GTEx Esophagus Muscularis SMARCA4 0.16 0.00 lasso 6 0.03 7.2e-03 -7.0 5.7 1.5e-08 -0.39 0.17 0.08 FALSE
6 GTEx Skin Sun Exposed Lower leg YIPF2 0.05 0.05 lasso 2 0.04 1.6e-04 -5.4 5.4 5.2e-08 -0.33 0.53 0.29 FALSE
7 GTEx Thyroid RGL3 0.32 0.17 enet 29 0.19 1.1e-14 4.7 5.5 4.6e-08 -0.09 1.00 0.00 TRUE
8 NTR Blood SMARCA4 0.07 0.06 lasso 11 0.06 9.0e-18 -5.5 6.1 9.1e-10 -0.38 1.00 0.00 FALSE
9 YFS Blood SMARCA4 0.02 0.01 enet 3 0.00 9.2e-03 -4.4 5.8 6.1e-09 -0.39 0.15 0.07 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C19orf52 0.04 0.04 blup 27 0.03 1.7e-04 -6.2 6.4 1.5e-10 -0.37 0.00 1.00 TRUE
11 The Cancer Genome Atlas Prostate Adenocarcinoma SPC24 0.06 0.00 enet 15 0.01 1.4e-02 -7.5 6.3 2.9e-10 -0.35 0.00 0.55 TRUE
12 The Cancer Genome Atlas Thyroid Carcinoma C19orf52 0.05 0.06 lasso 4 0.06 2.5e-06 -5.3 6.0 2.6e-09 -0.36 0.01 0.99 FALSE