Best TWAS P=9.31e-11 · Best GWAS P=3.85e-07 conditioned to 0.0593
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DNAJC11 | 0.03 | 0.03 | lasso | 5 | 0.04 | 3.1e-05 | 5.1 | 5.8 | 5.2e-09 | 0.89 | 0.03 | 0.95 | FALSE |
| 2 | CommonMind | Brain Pre-frontal Cortex | TNFRSF25 | 0.09 | 0.03 | enet | 22 | 0.06 | 1.1e-07 | 3.2 | 6.5 | 9.3e-11 | 0.54 | 0.08 | 0.82 | TRUE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | ACOT7 | 0.12 | 0.01 | lasso | 8 | 0.01 | 4.9e-02 | 3.9 | 5.2 | 1.8e-07 | 0.32 | 0.07 | 0.48 | FALSE |
| 4 | GTEx | Testis | THAP3 | 0.22 | 0.19 | lasso | 5 | 0.22 | 3.1e-10 | 4.9 | 5.7 | 1.5e-08 | 0.89 | 0.03 | 0.96 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DNAJC11 | 0.02 | 0.00 | blup | 74 | 0.01 | 9.1e-03 | 4.9 | 5.4 | 7.6e-08 | 0.90 | 0.02 | 0.61 | FALSE |