Hub : Genes

ACOT7

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1720	0.0420	3.1e-06	0.156	NA	0.112	NA	0.156	9.4e-13	NA	2.1e-09	NA	9.6e-13
2	GTEx	Breast Mammary Tissue (Male)	0.3004	0.1282	5.7e-03	0.042	NA	0.042	NA	0.062	3.9e-02	NA	4.0e-02	NA	1.5e-02
3	GTEx	Muscle Skeletal	0.1326	0.0390	1.2e-04	0.064	NA	0.064	NA	0.068	6.3e-07	NA	6.4e-07	NA	2.9e-07
4	GTEx	Skin Not Sun Exposed Suprapubic	0.1170	0.0500	1.6e-03	0.011	NA	-0.005	NA	0.015	7.5e-02	NA	7.4e-01	NA	4.9e-02
5	GTEx	Skin Sun Exposed Lower leg	0.2410	0.0580	3.1e-08	0.061	NA	0.085	NA	0.082	8.1e-06	NA	1.7e-07	NA	2.5e-07
6	GTEx	Testis	0.1680	0.0690	1.8e-03	0.037	NA	0.025	NA	0.020	8.9e-03	NA	2.7e-02	NA	4.3e-02
7	METSIM	Adipose	0.1151	0.0265	2.7e-15	0.142	0.120	0.138	0.133	0.134	1.4e-20	1.7e-17	4.5e-20	2.5e-19	1.7e-19
8	ROSMAP	Brain Pre-frontal Cortex	0.0524	0.0225	2.9e-03	-0.002	0.007	-0.002	0.008	-0.002	7.0e-01	4.2e-02	9.9e-01	2.5e-02	6.5e-01
9	TCGA	Prostate Adenocarcinoma	0.0444	0.0258	2.8e-03	0.030	0.017	0.026	NA	0.021	3.4e-04	5.7e-03	8.3e-04	NA	2.3e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	4.8	7.6	14.3	-2.7	-3.2	-2.4	-3.4	-1.4	2.3	-3.8	1.8	-2.9
Bipolar Disorder or Schizophrenia	3.0	7.2	21.5	-2.2	-2.7	-2.0	-4.6	-1.8	2.1	-3.4	1.6	-2.4
Depressed Affect (Nagel 2018)	1.5	3.2	10.6	1.9	1.3	1.4	1.7	1.4	-1.5	1.6	-3.2	1.4
Depression (Nagel 2018)	0.4	0.7	4.2	0.5	0.1	0.5	-0.6	0.3	-0.9	0.3	-2.1	0.3
Intelligence (Savage-Jansen 2018)	0.6	2.0	6.2	1.3	0.0	0.6	2.3	2.5	-1.5	0.8	0.8	0.8
Neuroticism (Nagel 2018)	2.8	6.6	8.2	2.7	2.9	2.2	2.4	2.4	-2.5	2.8	-2.7	2.5
Schizophrenia (2018)	0.8	1.6	8.6	-0.7	-0.8	-0.5	-2.9	-1.1	0.9	-1.2	0.6	-0.8
Schizophrenia vs Biploar Disorder	0.3	0.4	1.3	1.1	0.3	0.9	-0.0	0.5	-0.1	0.7	-0.6	0.7
Worry (Nagel 2018)	2.4	5.1	8.3	2.2	2.2	2.6	1.9	1.6	-2.2	2.9	-1.8	2.7
Alzheimer’s Disease (in mother)	0.8	0.9	2.9	1.7	0.5	1.0	0.3	0.8	-0.6	1.0	-0.7	1.2
Alzheimer’s Disease (in father)	0.2	0.3	1.1	-0.6	0.6	-0.2	-0.2	-0.2	-1.0	-0.3	0.5	-0.0
Alzheimer’s Disease (including proxy)	0.2	0.3	0.9	1.0	0.5	0.5	-0.3	0.1	-0.7	0.3	-0.7	0.7
Crohns Disease (2017)	2.3	5.0	10.4	-1.7	-1.6	-2.1	-2.2	-2.0	3.2	-2.5	2.1	-2.3
Irritable Bowel Disease (IBD)	2.7	6.4	16.6	-1.8	-1.8	-2.0	-3.2	-2.4	4.1	-2.4	2.2	-2.0
Ulcerative Colitis (UC)	1.8	3.4	9.2	-1.4	-1.1	-1.3	-2.9	-2.0	3.0	-1.4	1.2	-1.1
Major Depression (MDD)	0.4	0.5	1.6	0.9	0.0	0.8	-1.3	0.3	0.9	0.3	-0.9	0.0
Reaction Time	0.4	0.8	3.6	-0.1	-0.1	-0.1	-0.9	-1.9	0.5	-0.4	-1.4	-0.5
Verbal and Numeric Reasoning (VNR)	0.4	1.1	3.2	0.4	-0.1	0.2	1.8	1.1	-1.3	0.4	1.7	0.4
Breast Cancer	0.9	2.2	4.9	1.8	1.4	2.2	0.3	1.3	0.2	1.5	-0.9	2.1
Ovarian Cancer	0.2	0.3	0.8	-0.5	0.4	-0.7	-0.2	0.4	-0.1	-0.2	0.9	-0.7
Prostate Cancer	0.2	0.3	0.8	-0.8	-0.3	-0.5	-0.0	-0.8	-0.5	0.2	0.9	-0.3
Age at First Birth	0.7	1.1	3.7	0.7	0.9	1.4	-0.3	0.0	-0.6	1.9	0.4	1.4
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.4	0.6	2.3	0.5	0.9	0.5	1.5	-0.1	-0.6	0.5	-0.5	0.8
Coronary Artery Disease (CAD)	0.2	0.2	0.7	-0.2	-0.9	-0.2	0.8	0.6	-0.0	-0.3	0.5	0.0
Crohns Disease (2012)	3.4	5.5	11.3	-1.6	-2.0	-2.1	-2.3	-2.4	3.4	-2.4	2.3	-2.1
Mean Putamen Volume	3.3	3.8	5.8	-2.3	-2.2	-2.4	-2.0	-1.0	1.1	-2.0	1.8	-2.2
Fasting Glucose	0.7	0.8	1.7	0.6	1.3	0.9	0.2	-0.3	-0.8	1.1	-0.7	1.3
HbA1C	4.9	5.5	10.0	3.2	2.3	2.8	2.4	1.9	-1.4	2.3	-1.3	2.7
HDL Cholesterol	0.7	1.1	2.6	-0.9	-0.5	-1.1	-1.6	-0.8	1.4	-1.1	0.6	-1.0
LDL Cholesterol	0.5	0.8	1.4	1.2	1.2	1.1	0.4	0.9	-0.7	0.8	-0.3	1.1
Lupus	3.6	5.4	9.0	2.5	2.9	2.3	3.0	2.5	-1.2	2.5	-1.2	2.2
Neuroticism (2016)	1.3	1.8	2.8	1.6	1.7	1.5	1.0	1.4	-1.7	1.1	-0.2	1.4
Primary Biliary Cirrhosis	0.9	1.4	3.3	1.7	0.9	1.8	1.1	0.2	-0.1	1.2	-0.4	1.5
Rheumatoid Arthritis	0.7	1.0	2.1	-0.9	-1.4	-0.5	-0.7	-0.4	1.0	-1.5	1.3	-0.8
Schizophrenia (2014)	2.2	4.9	15.3	-1.3	-2.2	-1.0	-3.9	-1.9	2.3	-2.5	1.8	-1.6
Triglycerides	0.2	0.3	0.7	0.5	0.5	0.9	0.6	0.2	-0.4	0.4	0.0	0.7
Type 2 Diabetes (T2D) (2012)	0.8	0.9	1.5	-0.3	-1.0	-0.8	0.1	-1.0	1.2	-1.2	1.2	-1.0
Ulcerative Colitis	1.5	2.1	7.3	-0.7	-0.9	-0.3	-2.6	-1.3	2.7	-0.9	0.9	-0.4
Blood Eosinophil Count	0.7	5.7	9.7	2.9	2.8	2.9	2.1	2.0	-1.4	2.1	-1.3	3.1
Blood Platelet Count	0.5	6.3	9.3	2.8	2.9	2.9	2.6	1.7	-0.8	2.3	-2.6	3.0
Blood Red Count	0.1	1.0	6.6	-0.5	-0.0	-0.0	-1.4	-0.7	-0.2	0.0	-2.6	0.0
Blood White Count	0.0	0.2	0.5	0.6	0.3	0.4	0.0	-0.0	0.4	-0.1	0.7	0.3
Heel T-Score	0.3	2.1	16.1	-0.3	-0.3	-0.2	4.0	0.5	0.3	-0.1	1.5	-0.4
BMI	0.2	1.4	7.2	-1.2	-0.1	-1.3	2.7	-0.2	0.2	-1.0	0.8	-1.0
Height	0.3	5.3	13.0	2.7	1.7	3.1	0.0	1.8	-1.4	3.6	-0.5	3.0
Waist Hip Ratio (WHR)	3.2	14.6	25.6	5.0	3.4	5.1	3.0	2.5	-1.3	4.2	-3.6	4.7
Systolic Blood Pressure	0.6	3.0	10.6	-0.9	-1.5	-1.4	3.2	1.1	-1.9	-0.8	2.0	-1.4
Smoking Status	0.3	0.6	1.9	-0.6	-1.2	-0.5	-1.4	-0.5	0.5	-0.7	0.6	-0.6
Allergy or Eczema	0.3	0.8	1.3	0.9	1.0	1.2	-0.5	0.6	-1.1	0.3	-1.1	1.0
Cardiovascular Disease	2.4	8.0	27.2	1.5	1.0	1.1	5.2	3.7	-4.1	1.9	-2.0	1.6
Hypothyroidism (self reported)	0.1	0.3	1.2	0.1	-0.1	-0.5	0.2	-1.0	-0.1	-0.3	-1.1	-0.6
Respiratory disease	0.3	0.8	2.3	0.6	1.5	0.8	0.3	0.7	-0.7	1.3	-0.4	1.0
Type 2 Diabetes (T2D) (2018)	2.3	4.3	6.4	1.8	1.3	2.2	2.5	2.3	-2.4	2.1	-1.2	2.5
Lung FEV1/FVC ratio	0.5	2.6	22.0	0.1	0.8	0.1	4.7	-0.3	0.1	-0.4	0.3	0.1
Lung FVC	0.2	1.1	2.9	-1.3	0.1	-1.2	-0.6	-0.9	1.0	-0.7	1.7	-1.2
Neuroticism	0.5	1.3	2.9	1.6	1.3	1.1	0.6	0.6	-0.4	1.0	-1.7	0.9
Chronotype (morning person)	0.8	1.7	2.9	-1.2	-1.7	-1.7	0.5	-0.3	-1.1	-1.2	-1.7	-1.6
Hair Pigment	0.0	0.8	4.5	-1.1	-0.1	-0.5	-2.1	-0.9	-0.0	-0.3	0.1	-0.6
Tanning	0.3	3.9	8.5	-2.9	-2.2	-2.7	-1.4	-1.0	0.3	-2.4	0.7	-2.2
Hand grip strength (left)	0.1	0.3	1.3	-0.1	-0.8	-0.2	-0.8	-0.4	1.1	-0.1	0.4	0.0
Number of treatments/medications taken	0.5	0.9	2.4	0.2	0.4	0.2	1.1	1.6	-1.3	0.8	-1.1	0.6
Average weekly spirits intake	0.6	0.8	1.9	1.3	0.6	1.1	-0.3	-0.8	0.4	0.3	-1.4	0.9
Sensitivity / hurt feelings	1.1	1.8	2.9	1.6	1.5	1.4	1.6	1.2	-0.8	1.7	-0.0	1.4
Frequency of depressed mood in last 2 weeks	0.5	0.8	2.1	1.3	-0.1	1.0	-0.4	0.8	-0.8	0.4	-1.4	0.7
Hearing difficulty/problems: Yes	3.1	4.8	13.1	-0.9	-2.0	-1.4	-2.4	-2.9	3.6	-2.4	0.5	-1.7
Relative age of first facial hair	0.4	0.9	3.5	-0.7	-0.9	-0.4	-1.5	-0.4	0.8	0.1	1.9	-0.1
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.6	-0.9	-0.3	-1.3	0.3	-0.6	-0.7	-0.5	-0.9	-0.9
Ever used hormone-replacement therapy (HRT)	0.1	0.2	1.0	-0.5	-0.1	0.1	-1.0	-0.4	-0.1	0.4	-0.3	0.1
Ever had hysterectomy (womb removed)	1.0	1.1	1.9	-0.6	-1.1	-0.6	-1.1	-1.2	1.0	-1.3	1.4	-0.7
Systolic blood pressure, automated reading	0.7	2.0	4.5	-1.4	-1.4	-1.6	2.1	0.7	-1.0	-1.1	1.5	-1.5
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	1.1	0.7	0.4	0.8	0.7	0.9	-0.9	1.0	0.2	1.1
Angina	0.7	1.0	2.6	1.3	-0.1	0.7	1.5	1.2	-0.2	0.0	-1.6	0.5
Medication for hormone replacement therapy	0.5	0.5	1.9	0.2	0.4	0.9	-1.4	-0.4	1.1	0.4	-0.2	0.5
Vitamin and mineral supplements	0.4	0.5	2.8	0.9	-0.2	0.7	1.7	0.1	-0.1	0.4	0.1	0.6
Supplements: Zinc	2.3	2.5	7.1	-1.2	-0.2	-1.1	-2.7	-1.8	2.6	-1.3	0.1	-1.1
Medication: Co-codamol	1.9	2.3	5.0	1.2	0.8	1.4	2.2	0.9	-1.4	1.7	-2.0	1.3
Medication: Metformin	2.1	2.9	4.5	1.6	1.2	1.9	2.1	2.1	-1.7	1.5	-1.2	1.9
Diabetes (father)	0.7	0.9	1.6	0.7	0.7	1.2	-0.4	-0.5	1.3	1.1	0.9	1.2
Diabetes (mother)	1.2	1.6	3.0	0.9	1.7	1.3	1.4	0.2	-1.5	1.0	-1.4	1.2
Severe depression (siblings)	0.2	0.2	0.4	0.6	0.6	0.4	0.1	0.1	0.4	0.3	0.5	0.6
Pack years adult smoking proportion	1.2	1.9	5.1	0.9	-0.5	0.6	1.8	2.0	-2.3	1.4	-0.8	0.8
Impedance of leg (right)	0.3	1.5	6.9	1.1	0.5	0.9	1.3	0.9	-0.7	1.0	-2.6	0.6
Leg fat-free mass (left)	0.1	0.4	1.8	-0.1	-0.5	-0.3	0.5	-0.4	1.0	-0.0	1.4	-0.1
Trunk fat percentage	0.3	1.2	8.0	-0.3	-0.5	-0.9	2.8	0.9	-0.7	-0.3	-0.0	-0.8
Hand grip strength (right)	0.1	0.3	1.1	0.0	-0.5	-0.1	-0.8	-0.4	0.8	-0.0	1.0	0.1
Townsend deprivation index at recruitment	0.3	0.4	1.2	0.3	0.7	-0.1	-0.2	-1.1	0.3	0.6	-1.1	0.0
Current tobacco smoking	0.1	0.2	0.6	-0.3	-0.7	-0.6	0.2	-0.0	-0.8	-0.4	-0.0	-0.3
Average weekly fortified wine intake	0.6	0.7	1.5	0.5	1.2	0.8	0.8	0.9	-0.4	1.0	0.1	1.1
Maternal smoking around birth	0.4	0.5	1.2	0.5	0.9	0.0	1.1	0.5	-0.8	0.6	-1.1	0.2
Fed-up feelings	1.4	2.5	6.8	1.8	0.3	1.3	1.5	1.8	-0.7	1.7	-2.6	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	1.6	-0.3	-0.9	-0.9	-1.0	-0.8	0.6	-1.3	-0.7	-1.2
Relative age voice broke	0.2	0.3	1.8	0.0	-0.7	-0.1	-0.4	0.1	-0.1	-0.2	1.4	0.0
Taking other prescription medications	1.4	2.2	3.8	1.3	1.8	1.2	1.3	1.3	-1.9	1.8	-0.7	1.6
Age when periods started (menarche)	0.2	0.4	1.5	0.9	0.7	0.5	-0.3	-0.3	-0.3	0.4	-1.2	0.1
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.5	-0.5	0.6	-0.1	-0.1	-0.7	-0.6	0.0	0.3	-0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.0	8.2	-0.8	-1.6	-1.3	2.9	1.3	-1.0	-0.2	1.1	-0.9
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	2.0	0.6	0.3	1.1	0.4	1.0	-0.6	1.4	-0.7	1.1
Qualifications: CSEs or equivalent	1.0	1.3	4.7	1.2	0.7	1.4	0.5	0.4	-0.5	0.6	-2.2	1.6
Serious illness, injury or assault to yourself	0.2	0.3	1.0	-0.3	-1.0	-0.3	-0.4	-0.6	-0.4	-0.3	-0.4	-0.1
High blood pressure	1.1	3.1	13.9	0.6	-0.0	-0.2	3.7	2.6	-2.4	0.7	-0.4	0.1
Hayfever, allergic rhinitis or eczema	0.4	0.9	2.5	1.0	0.8	1.6	-0.5	0.2	-0.7	0.4	-1.2	1.3
Multivitamins +/- minerals	1.2	1.5	6.8	-1.3	-0.7	-0.8	-2.6	-0.5	1.3	-1.1	0.4	-0.8
Stomach or abdominal pain in last month	1.2	1.5	3.3	1.8	1.4	1.7	0.3	0.4	0.4	1.6	-0.5	1.6
Supplements: Glucosamine	2.8	3.7	6.6	-2.0	-1.4	-2.1	-2.2	-1.5	1.8	-2.6	0.6	-2.2
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	4.6	0.4	1.7	0.7	2.1	0.2	-1.5	0.7	-0.7	0.6
Medication: Atenolol	1.6	2.0	9.6	1.2	0.3	0.9	3.1	1.8	-1.2	0.6	-0.3	0.7
Medication: Levothyroxine sodium	0.4	0.7	1.6	1.2	0.2	0.8	-0.6	-1.3	0.8	-0.1	-1.1	0.3
Sitting height	0.3	2.2	5.7	2.0	0.9	2.2	-0.4	0.7	-0.2	2.4	0.1	1.9
Chronic bronchitis/emphysema (father)	0.0	0.0	0.1	0.1	-0.1	-0.2	-0.1	0.4	-0.2	-0.1	-0.2	-0.3
High blood pressure (mother)	2.9	4.1	17.7	1.8	0.8	1.2	4.2	2.2	-2.4	1.0	-1.0	1.1
Body mass index (BMI)	0.3	1.4	6.2	-1.0	-0.6	-1.4	2.5	-0.1	-0.2	-1.2	0.6	-1.1
Impedance of leg (left)	0.4	1.8	6.9	1.4	0.7	1.1	1.3	1.0	-1.0	1.2	-2.6	0.8
Leg predicted mass (left)	0.1	0.4	1.6	-0.1	-0.5	-0.2	0.6	-0.4	0.9	0.0	1.3	-0.0
Trunk fat mass	0.2	1.0	8.0	-0.0	-0.4	-0.5	2.8	0.8	-0.5	-0.1	0.0	-0.4
Waist circumference	0.6	2.0	10.6	1.4	1.1	1.1	3.2	1.0	-0.4	0.9	-0.2	1.1
Number of incorrect matches in round	0.3	0.6	1.6	1.1	1.2	0.7	-0.0	0.0	0.8	0.7	0.4	0.7
Past tobacco smoking	0.2	0.4	1.3	-0.4	0.9	-0.5	1.0	0.7	-1.1	0.1	-0.2	-0.1
Alcohol usually taken with meals	0.6	0.9	5.5	0.0	0.7	0.3	-0.1	-0.2	1.4	0.4	2.4	0.1
Nervous feelings	5.2	9.6	14.6	3.5	3.3	3.6	2.9	3.0	-2.5	3.8	-0.5	3.6
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.9	8.3	1.9	1.3	1.4	0.1	-0.1	-0.4	0.9	-2.9	1.0
Hearing difficulty/problems with background noise	4.3	6.8	17.8	-1.8	-1.9	-1.6	-4.2	-3.8	3.2	-2.5	0.3	-2.0
Hair/balding pattern: Pattern 2	0.8	1.0	2.7	-1.6	-0.0	-1.6	0.1	-1.4	-0.1	-0.5	-0.5	-1.3
Had menopause	0.6	0.8	3.6	-1.0	0.2	-0.5	-1.9	-0.2	0.2	0.1	1.3	-0.3
Had other major operations	0.4	0.4	2.8	-0.4	-0.4	0.1	-1.7	-0.7	0.5	-0.1	-0.2	0.3
Forced vital capacity (FVC)	0.2	0.8	1.5	0.2	1.0	0.6	-1.2	-0.7	1.2	0.8	1.1	0.6
Heel bone mineral density (BMD) T-score, automated (right)	1.6	3.6	7.5	-2.1	-2.7	-2.7	1.5	0.1	0.6	-1.6	1.5	-2.4
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	3.5	-0.6	-1.4	-0.8	-1.2	-0.5	0.5	-1.0	1.9	-0.5
Qualifications: None of the above	1.3	2.9	6.9	0.8	1.9	1.0	2.3	1.0	-1.6	1.7	-2.6	1.4
Financial difficulties in last 2 years	0.5	0.7	1.8	-1.4	-0.8	-0.8	-0.4	-1.2	0.7	-1.0	-0.1	-0.4
Mouth/teeth dental problems	0.2	0.2	1.0	0.3	1.0	0.3	0.4	0.6	-0.1	0.6	0.1	0.2
Heart attack	0.6	0.8	2.3	0.8	-0.8	0.5	1.1	1.5	-0.7	0.4	-1.2	0.6
Allergy	1.0	2.4	5.2	-1.8	-1.6	-2.3	-0.1	-0.7	0.8	-1.3	1.7	-2.2
Pain all over the body in last month	1.4	1.5	3.8	-1.1	-1.9	-1.5	-0.0	-0.1	0.3	-1.2	-1.6	-1.6
Diabetes (self-reported)	3.3	5.1	9.2	2.1	1.4	2.2	3.0	2.5	-2.2	2.0	-1.8	2.5
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	2.2	1.0	1.5	1.1	-0.2	1.4	-1.4	0.9	0.4	0.8
Medication: Ramipril	0.5	0.6	2.9	0.6	-0.7	-0.0	1.7	0.9	-0.8	0.4	-0.3	-0.1
Medication: Simvastatin	1.1	1.6	6.2	0.2	1.3	0.4	2.5	1.2	-1.8	0.3	-0.5	0.8
Fluid intelligence score	0.7	1.5	4.4	-1.4	-1.3	-1.3	0.1	-0.5	-0.6	-1.3	2.1	-1.3
Illnesses of siblings	0.5	0.7	3.8	-0.7	-0.0	-0.7	-2.0	-0.6	0.4	-0.5	0.2	-1.0
Neuroticism score	0.9	1.9	4.7	2.2	1.3	1.4	1.0	0.8	-0.5	1.3	-1.8	1.3
Weight	0.1	0.6	4.5	-0.0	-0.3	-0.3	2.1	0.2	0.0	0.1	0.6	-0.0
Impedance of arm (right)	0.1	0.3	0.7	0.7	-0.0	0.7	-0.2	0.8	0.2	0.8	-0.8	0.3
Arm fat percentage (right)	0.3	1.1	6.9	-0.5	-0.5	-0.9	2.6	0.3	0.0	-0.8	0.3	-0.8
Trunk fat-free mass	0.1	0.4	0.9	0.6	0.1	0.6	0.2	-0.6	0.9	0.7	0.8	0.8
Hip circumference	0.2	0.9	4.0	-0.6	-0.5	-1.0	2.0	-0.1	0.5	-0.3	1.3	-0.7
Time employed in main current job	1.1	1.3	4.6	0.2	1.5	0.4	0.8	1.5	-2.1	0.8	-0.9	0.7
Alcohol intake versus 10 years previously	1.4	2.0	4.6	1.5	1.3	2.1	0.1	0.9	-1.3	1.4	-1.1	2.0
Father’s age at death	0.3	0.5	1.7	-0.6	0.5	-0.0	-1.0	-0.1	-1.3	0.1	0.9	0.2
Worrier / anxious feelings	1.3	2.4	4.0	1.7	1.0	1.6	1.5	1.1	-2.0	2.0	-0.9	1.7
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.1	6.0	2.4	0.7	1.6	0.6	1.4	-0.7	1.2	-1.9	1.6
Falls in the last year	0.4	0.5	2.1	0.5	-0.7	-0.3	0.4	1.5	-0.7	0.6	-0.8	0.1
Hair/balding pattern: Pattern 3	1.7	2.6	3.9	1.6	2.0	1.6	1.8	1.1	-1.1	1.9	-1.7	1.5
Number of live births	0.7	1.0	4.1	-0.3	-0.6	-0.4	2.0	1.6	-0.4	-0.4	-1.2	0.1
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	2.3	-0.7	1.3	-0.1	-0.3	-1.5	1.5	0.2	0.9	-0.1
Pulse rate	0.9	1.5	4.7	-1.1	-2.2	-1.3	-0.6	-0.2	0.1	-1.2	-1.4	-1.3
Happiness	0.9	1.1	2.7	1.1	0.6	1.2	0.5	1.6	-1.0	0.8	0.6	1.4
Noisy workplace	1.2	1.4	6.6	-0.8	0.5	-0.8	-1.6	-2.6	1.1	-0.3	-0.7	-0.5
Qualifications: A levels/AS levels or equivalent	0.4	0.9	2.8	-0.4	-0.9	-0.2	-1.0	0.2	1.6	-0.6	1.7	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.4	1.3	-0.6	0.7	0.4	1.5	-0.6	0.2	-0.4	1.0
Mouth/teeth dental problems: Dentures	0.2	0.4	1.7	-0.4	-1.3	-0.3	-0.3	-0.9	0.6	0.2	-0.4	-0.1
Asthma	1.2	2.3	3.0	1.6	1.7	1.4	1.6	1.7	-1.1	1.6	-1.0	1.6
Medication: Ibuprofen (e.g. Nurofen)	2.4	3.0	4.5	-1.4	-2.1	-1.7	-2.1	-1.8	1.9	-1.9	0.5	-1.8
Medication: Cholesterol lowering	1.4	2.1	8.9	0.6	0.5	0.4	3.0	1.7	-2.3	0.6	-0.7	0.8
Depression (self-reported)	0.6	0.7	1.6	0.7	1.0	1.0	0.6	0.5	-0.5	1.2	-0.1	1.3
Medication: Lansoprazole	1.3	1.5	3.8	-1.6	-0.6	-1.9	-0.4	-1.0	0.5	-1.2	-0.7	-1.9
Prospective memory result	0.5	0.7	5.0	-0.0	0.3	0.3	-0.0	-0.6	0.5	0.4	-2.2	0.2
Lung cancer (father)	2.0	2.3	3.8	1.3	1.9	1.2	0.8	0.8	-1.8	1.6	-1.9	1.8
Illnesses of mother	1.2	1.4	3.3	-1.3	-1.2	-0.7	-1.8	-1.4	1.7	-0.4	0.8	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.8	2.9	0.3	1.7	0.8	0.5	-1.1	0.8	1.0	0.3	0.6
Pulse wave Arterial Stiffness index	4.2	4.9	9.7	0.9	2.5	1.0	2.7	2.3	-3.1	2.4	-2.4	1.6
Impedance of arm (left)	0.1	0.5	1.1	0.8	0.2	0.7	-0.1	1.1	0.1	1.0	-1.1	0.5
Arm fat mass (right)	0.2	0.9	5.7	-0.4	-0.6	-0.8	2.4	0.2	0.2	-0.6	0.4	-0.6
Trunk predicted mass	0.1	0.4	1.0	0.5	0.1	0.6	0.1	-0.6	1.0	0.6	0.8	0.7
Standing height	0.2	2.1	5.2	2.0	0.5	2.0	-0.9	0.4	0.7	2.3	-0.0	1.9
Length of working week for main job	1.1	1.2	5.5	0.1	-0.3	0.1	-0.5	-2.0	2.3	-0.3	0.7	-0.2
Exposure to tobacco smoke at home	1.2	1.3	2.9	1.2	0.4	1.0	1.3	1.7	-1.1	1.5	-0.9	0.8
Breastfed as a baby	0.5	0.7	2.2	-1.5	-0.8	-1.1	0.0	-0.8	-0.2	-0.6	-0.6	-0.7
Tense / ‘highly strung’	0.9	1.6	4.9	0.9	0.6	1.1	1.1	0.6	-2.2	1.6	-0.8	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	2.0	1.4	-0.1	0.6	0.3	0.4	0.3	0.2	-0.7	0.3
Hair/balding pattern: Pattern 4	0.2	0.6	2.6	0.1	-1.2	-0.3	0.1	0.9	-0.1	-0.4	1.6	-0.2
Birth weight of first child	0.3	0.6	3.0	-0.3	-0.9	0.0	-1.7	0.0	-0.3	-0.1	1.0	0.2
Peak expiratory flow (PEF)	0.3	0.6	2.6	-0.5	1.6	-0.0	1.4	-0.5	0.1	0.4	0.4	-0.1
Pulse wave reflection index	1.1	1.3	4.7	0.0	1.4	-0.2	1.7	0.9	-2.2	1.1	-0.5	0.3
Ever highly irritable/argumentative for 2 days	0.9	1.1	3.1	-1.1	-1.8	-0.7	-1.7	0.3	0.7	-0.9	-0.6	-0.4
Loud music exposure frequency	1.1	1.3	5.5	-0.7	-0.6	-0.2	-1.8	-2.3	0.9	-0.6	-0.6	-0.3
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.8	0.5	-0.5	0.1	-0.0	0.5	0.7	-0.7	0.9	-0.3
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.3	0.2	0.5	0.3	0.6	0.2	-0.5	-0.2	-0.1	0.1
Blood clot in the leg (DVT)	0.2	0.3	0.5	-0.3	0.2	-0.5	-0.6	-0.6	-0.2	-0.7	0.6	-0.4
Medication: Paracetamol	0.7	1.1	4.4	-0.4	-1.1	-0.8	-0.8	-0.2	0.9	-1.1	-2.1	-0.8
Headache pain in last month	0.7	1.2	2.6	1.4	1.3	1.5	-0.4	0.0	-0.2	0.7	-1.6	1.3
Medication for cholesterol, blood pressure or diabetes	1.2	1.9	9.9	-0.6	-0.5	-0.3	-3.1	-1.7	1.8	-0.7	-0.1	-0.6
Glaucoma (self-reported)	0.8	1.0	2.2	-0.7	-0.8	-1.2	-1.2	0.7	0.3	-1.1	1.5	-0.9
Gout (self-reported)	1.1	1.4	4.2	0.6	2.0	0.6	1.5	0.9	-1.4	1.3	-0.5	1.0
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	2.2	0.4	0.1	0.0	-0.8	-1.5	1.0	-0.7	-0.5	-0.4
Medication: Amlodipine	0.9	1.3	4.5	-0.0	-0.2	0.5	1.3	1.6	-1.2	0.7	2.1	0.6
Medication: Ventolin 100micrograms inhaler	0.7	0.9	2.1	1.0	1.4	0.4	0.9	1.0	0.1	0.8	-1.3	0.6
Birth weight	0.3	0.6	2.2	-0.8	0.1	-0.0	-1.4	-1.5	0.4	0.1	-0.3	-0.1
Chronic bronchitis/emphysema (mother)	0.9	1.1	2.3	-1.0	-0.1	-1.5	-1.1	-0.5	0.1	-1.5	-0.8	-1.5
High blood pressure (siblings)	0.5	0.8	2.6	0.7	-0.8	0.5	1.6	1.1	-1.1	0.3	0.1	0.8
Forced vital capacity (FVC), Best measure	0.3	1.1	2.7	0.8	1.6	1.2	-0.3	-0.5	0.7	1.5	0.5	1.1
Body fat percentage	0.4	1.5	10.8	-0.3	-0.3	-0.8	3.3	0.9	-0.7	-0.3	-0.4	-0.7
Leg fat percentage (right)	0.7	2.5	18.5	-0.4	-0.0	-1.0	4.3	0.7	-1.0	-0.4	-0.7	-0.7
Arm fat-free mass (right)	0.0	0.1	0.4	0.2	-0.2	0.1	0.6	-0.3	0.3	0.2	0.6	0.2
Exposure to tobacco smoke outside home	1.6	2.1	7.3	1.6	1.8	1.8	-0.3	-1.0	0.4	0.7	-2.7	1.1
Comparative body size at age 10	0.4	1.0	5.7	-0.2	-0.1	-0.6	2.4	0.8	-0.6	-1.4	0.3	-0.2
Number of full brothers	0.5	0.7	1.3	-0.8	-0.4	-0.9	1.0	-0.7	-0.3	-1.1	-0.8	-1.0
Worry too long after embarrassment	0.2	0.3	0.5	0.7	0.7	0.3	0.3	0.7	0.5	0.7	-0.3	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.1	1.0	0.3	0.8	-0.4	-0.0	-0.2	0.4	-1.1	0.9
Wheeze or whistling in the chest in last year	2.4	4.2	5.7	1.9	1.4	1.7	2.0	2.2	-2.4	2.3	-2.2	2.2
Number of children fathered	0.0	0.0	0.2	0.2	0.5	-0.0	0.2	-0.2	-0.0	0.3	-0.1	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.7	-0.6	-0.1	0.0	-1.2	-0.3	0.1	0.1	1.3	0.2
Age at first live birth	1.9	3.4	8.5	-1.6	-1.3	-1.2	-2.5	-1.6	1.1	-1.9	2.9	-1.7
Pulse wave peak to peak time	3.5	4.2	9.4	-0.5	-2.1	-0.6	-2.7	-2.1	3.1	-2.0	2.4	-1.2
Health satisfaction	0.3	0.4	1.9	1.4	0.2	0.7	0.2	0.3	-0.4	0.4	-0.5	0.8
Shortness of breath walking on level ground	0.4	0.5	2.8	-0.1	-0.6	-0.4	0.1	0.0	0.9	-0.4	-1.7	-0.6
Qualifications: College or University degree	1.9	6.1	12.5	-2.2	-2.0	-1.3	-3.2	-2.1	3.4	-2.1	3.5	-1.4
Eye problems/disorders: None of the above	2.6	3.0	5.1	1.7	1.9	2.1	2.0	-0.2	-1.0	2.3	-1.3	2.1
Mouth/teeth dental problems: Loose teeth	0.3	0.3	0.9	0.3	-0.8	-0.2	-0.7	-0.1	0.5	-0.6	-0.9	-0.4
Emphysema/chronic bronchitis	0.2	0.3	1.3	0.3	-0.7	0.5	0.0	-0.4	-0.0	0.2	-1.1	0.2
Medication for pain relief, constipation, heartburn	0.6	1.0	8.1	-0.7	0.2	0.1	-0.3	-0.2	0.2	0.2	2.9	-0.0
Neck or shoulder pain in last month	1.3	1.9	5.1	1.6	-0.1	1.8	0.8	0.0	-1.0	0.9	-2.3	1.9
Medication: Blood pressure	1.3	2.4	12.9	0.9	0.7	0.2	3.6	1.9	-1.5	0.9	0.5	0.6
Angina (self-reported)	0.8	1.1	3.0	1.3	0.3	0.8	1.6	1.1	-0.3	0.2	-1.7	0.7
Migraine (self-reported)	1.2	1.4	3.1	-1.6	-1.0	-1.3	-1.2	-0.3	0.4	-1.2	1.8	-1.2
Medication: Ibuprofen	2.2	2.6	4.9	-1.5	-2.2	-1.8	-1.8	-1.2	1.4	-1.8	0.6	-1.6
Medication: Allopurinol	0.1	0.1	0.3	0.4	0.4	-0.1	0.6	0.5	-0.2	0.3	-0.1	0.1
Medication: Omeprazole	2.9	3.4	5.7	2.1	1.3	2.2	2.0	1.3	-2.4	1.6	-1.3	2.0
Medication: Seretide 50 evohaler	1.0	1.1	2.6	1.2	0.8	1.1	1.1	1.6	-0.4	0.6	-1.3	0.8
Mean time to correctly identify matches	0.2	0.4	2.1	0.0	0.1	0.1	-0.7	-1.4	0.3	-0.2	-1.1	-0.1
Heart disease (mother)	0.7	0.9	3.1	-0.6	-0.7	-1.1	-0.7	-0.7	1.8	-1.2	0.1	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.0	0.4	1.0	0.4	1.0	0.1	-0.5	0.1	-1.0	0.5
Whole body fat mass	0.3	1.1	8.8	-0.1	-0.3	-0.6	3.0	0.7	-0.4	-0.2	-0.1	-0.5
Leg fat mass (right)	0.4	1.4	9.4	-0.6	-0.5	-1.1	3.1	0.2	-0.2	-0.7	0.1	-0.9
Arm predicted mass (right)	0.0	0.1	0.3	0.2	-0.2	0.0	0.5	-0.4	0.4	0.2	0.5	0.2
Pulse rate, automated reading	0.6	2.0	11.4	0.5	-1.2	0.1	1.3	1.3	-1.1	0.3	-3.4	-0.0
Alcohol intake frequency.	0.6	1.5	2.9	0.7	0.7	0.9	1.6	1.5	-1.3	0.9	-1.7	1.1
Comparative height size at age 10	0.3	1.4	3.3	1.4	0.6	1.7	0.1	0.1	0.9	1.8	-0.6	1.8
Number of full sisters	1.4	1.7	3.7	-1.6	-1.4	-1.9	-0.4	0.2	0.6	-1.5	-0.6	-1.9
Suffer from ‘nerves’	1.0	1.6	3.2	1.2	1.4	1.2	1.1	0.3	-1.4	1.8	-1.3	1.3
Overall health rating	0.5	1.0	4.5	0.6	0.4	0.0	2.1	0.2	-1.2	0.3	-1.4	0.2
Chest pain or discomfort	0.5	0.8	3.8	0.3	0.1	-0.3	1.7	0.2	-0.1	-0.3	-1.9	-0.2
Had major operations	0.3	0.3	1.8	-0.2	0.1	-0.0	-0.8	-1.3	0.3	-0.4	-0.2	-0.1
Age at last live birth	1.1	1.6	6.1	-1.0	-0.8	-1.0	-0.8	-1.2	0.6	-1.4	2.5	-1.2
Family relationship satisfaction	0.2	0.3	1.2	0.1	-1.1	0.1	-0.9	0.2	0.2	-0.4	0.0	0.2
Leg pain on walking	0.6	0.7	3.9	-0.1	0.2	-1.0	0.5	0.3	-0.8	-0.3	-2.0	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.1	1.2	-1.0	0.7	0.0	-0.4	-0.0	0.2	-1.5	0.5
Commuting to job workplace: Car/motor vehicle	0.9	1.0	2.6	0.9	1.6	1.2	1.1	0.9	-0.4	1.0	-0.5	1.0
Illness, injury, bereavement, stress in last 2 years	1.3	1.5	3.4	-1.4	-0.3	-1.4	-0.9	-1.3	1.0	-1.4	1.0	-1.8
Medication: Aspirin	0.7	1.0	5.0	0.8	-0.3	0.4	0.8	0.9	-0.8	0.6	-2.2	0.7
Supplements: Vitamin C	0.3	0.4	1.5	0.0	1.2	-0.4	-0.7	-1.0	0.0	0.1	-0.2	-0.4
Knee pain experienced in last month	1.2	1.8	3.5	-1.5	-1.9	-1.7	-1.0	-0.8	0.5	-1.6	1.0	-1.6
Hypertension (Self-reported)	1.1	3.0	14.2	0.8	-0.0	-0.2	3.8	2.6	-2.3	0.7	-0.3	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.7	3.1	-1.1	-0.2	-1.2	-1.8	-1.6	1.5	-1.7	-0.3	-1.5
Illnesses of father: Heart disease	0.3	0.4	1.1	0.6	-1.1	0.9	0.8	0.1	-0.4	-0.6	-0.3	0.4
Illnesses of siblings: Diabetes	0.2	0.3	0.9	-1.0	0.2	-0.2	0.7	-0.5	-0.2	0.5	-0.7	0.2
Smoking status: Previous	0.4	0.6	1.9	-0.1	-0.9	0.0	-1.3	-0.5	1.4	-0.3	0.7	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	2.9	1.7	0.9	1.7	0.4	1.2	-0.4	1.1	-0.9	1.7
Whole body fat-free mass	0.1	0.3	1.0	0.3	-0.1	0.2	0.3	-0.6	1.0	0.4	1.0	0.4
Leg fat-free mass (right)	0.1	0.4	2.1	0.0	-0.3	-0.1	0.2	-0.5	0.9	0.1	1.4	0.0
Arm fat percentage (left)	0.3	1.2	7.1	-0.7	-0.6	-1.1	2.7	0.4	-0.0	-0.9	0.2	-0.9
Average weekly red wine intake	1.0	1.5	2.6	-1.2	-0.4	-1.3	-1.3	-1.3	1.4	-1.0	1.6	-1.2
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.8	-0.9	-0.3	-0.5	-0.1	-0.0	-0.7	-0.6	0.6	-0.5
Mood swings	0.7	1.3	3.1	1.8	0.8	1.3	0.3	0.7	-0.4	1.4	-1.7	1.1
Loneliness, isolation	0.6	0.9	2.5	1.1	1.1	0.9	0.6	0.6	-0.7	0.6	-1.6	0.7
Long-standing illness, disability or infirmity	0.4	0.6	1.1	0.6	0.0	0.6	1.1	0.6	-0.9	0.8	-0.9	0.9
Ever had bowel cancer screening	1.1	1.2	2.6	1.6	0.7	1.6	1.0	0.5	-0.4	1.2	-0.5	1.6
Diabetes diagnosed by doctor	3.3	5.3	9.4	2.0	1.6	2.3	3.1	2.5	-2.5	2.1	-1.7	2.6
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	4.5	1.7	1.3	1.3	1.2	0.2	0.2	1.3	-2.1	1.2
Friendships satisfaction	0.4	0.5	1.5	0.4	-0.2	0.6	-0.9	1.2	-1.0	-0.2	0.3	0.6
Qualifications: nursing, teaching	0.3	0.5	2.5	0.1	-0.6	0.1	-1.1	-0.2	1.6	-0.4	0.4	-0.0
Commuting to job workplace: Walk	0.3	0.3	1.3	0.6	-0.5	0.1	-0.4	-0.6	-0.2	0.1	-1.1	0.3
Eye problems/disorders: Cataract	0.5	0.6	1.9	-0.3	-0.4	-0.4	-0.7	1.4	0.2	-0.7	1.4	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.9	0.9	-0.2	0.6	-0.5	-0.2	1.4	-0.7	-0.0	0.6
Medication for cholesterol	0.3	0.4	1.3	-0.5	0.1	-0.4	-0.9	-0.7	0.7	-0.2	1.1	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.9	0.7	-0.8	0.1	0.6	-0.1	0.0	-0.2	-1.4	-0.0
Back pain experienced in last month	1.5	2.2	4.9	1.2	2.1	1.1	1.1	0.6	-0.6	2.2	-1.5	1.8
Mineral and other dietary supplements	3.2	4.2	9.8	2.1	1.3	2.2	3.1	1.6	-1.7	2.4	-0.9	2.4
Breast cancer (self-reported)	0.5	0.6	2.1	0.6	1.4	0.6	0.2	0.5	-0.5	1.2	0.2	0.4
Asthma (self-reported)	1.4	2.8	3.8	1.8	1.8	1.5	1.9	1.9	-1.1	1.8	-1.1	1.8
Osteoporosis (self-reported)	1.3	1.6	2.7	1.0	1.4	1.0	1.0	1.4	-1.6	1.2	-1.0	1.3
Osteoarthritis (self-reported)	1.0	1.3	2.2	-1.5	-1.2	-1.3	-0.9	-1.1	-0.0	-1.3	-1.0	-1.2
Medication: Aspirin	0.6	0.8	4.0	0.4	-0.5	-0.0	0.9	0.9	-1.0	0.4	-2.0	0.4
Medication: Gliclazide	1.2	1.3	2.6	1.4	0.8	1.6	1.6	1.0	-0.9	0.5	-0.3	1.4
Illnesses of father: None of the above (group 1)	0.3	0.3	0.9	0.5	0.9	0.3	0.5	0.5	-0.2	0.9	-0.1	0.4
Smoking status: Current	0.1	0.2	0.6	-0.2	-0.8	-0.5	0.0	-0.2	-0.7	-0.4	-0.1	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	2.4	0.4	1.5	0.9	0.3	-0.8	1.2	0.3	0.2	0.9
Whole body water mass	0.1	0.3	1.2	0.3	-0.1	0.3	0.3	-0.5	0.9	0.4	1.1	0.5
Leg predicted mass (right)	0.1	0.4	2.3	-0.0	-0.4	-0.2	0.2	-0.6	0.9	0.0	1.5	-0.0
Arm fat mass (left)	0.2	1.0	5.5	-0.7	-0.7	-1.0	2.4	0.1	0.2	-0.8	0.6	-0.8
Number of self-reported non-cancer illnesses	0.9	1.6	4.6	0.9	0.8	0.8	2.1	1.4	-1.7	1.2	-0.2	1.1
Average weekly champagne plus white wine intake	0.1	0.1	0.4	0.2	0.6	0.2	0.1	0.2	0.6	0.3	-0.4	0.3
Miserableness	1.9	3.3	7.1	2.7	1.7	1.9	1.5	0.9	-1.3	1.5	-2.5	1.7
Guilty feelings	0.1	0.1	0.2	0.2	0.2	-0.4	-0.5	-0.1	-0.3	-0.4	-0.3	-0.2
Wears glasses or contact lenses	0.7	0.9	2.1	-0.8	-1.3	-0.7	-1.5	-1.0	0.6	-0.7	-0.1	-0.9
Ever taken oral contraceptive pill	0.9	1.0	2.4	-1.4	-1.2	-1.5	0.5	-0.0	0.1	-1.1	-0.3	-1.2
Hearing aid user	0.6	0.7	1.6	-0.1	-1.2	-0.8	0.9	0.2	0.4	-0.8	-1.3	-0.7
Mother’s age at death	0.8	1.0	2.0	1.0	1.4	1.3	0.0	0.9	-0.9	0.9	0.8	1.2
Financial situation satisfaction	0.3	0.4	1.1	1.0	0.4	0.8	-1.1	-0.1	0.1	0.3	-0.4	0.5
Tinnitus: Yes, now most or all of the time	3.1	3.6	5.7	-2.1	-1.6	-2.4	-1.9	-1.6	2.1	-2.1	0.1	-2.1
Commuting to job workplace: Public transport	0.5	0.6	2.5	-0.6	-1.6	-1.1	0.2	-0.3	0.7	-0.6	0.4	-0.7
Eye problems/disorders: Glaucoma	1.1	1.3	2.8	-1.1	-1.3	-1.7	-1.5	0.2	0.8	-1.1	0.7	-1.2
Medication: Blood pressure	0.8	1.5	5.0	0.4	0.1	0.1	2.2	1.5	-2.1	0.1	-1.1	-0.0
Pain type(s) experienced in last month: Hip pain	1.7	2.1	3.1	1.5	1.7	1.3	1.3	0.8	-1.2	1.8	-1.5	1.7
Supplements: Fish oil (including cod liver oil)	0.8	1.0	3.0	-1.0	-0.9	-1.1	-1.7	0.1	0.6	-0.9	0.5	-1.3
High cholesterol (Self-reported)	1.3	2.2	6.9	0.7	1.3	0.6	2.6	1.1	-2.2	1.0	-1.7	1.0
Medication: Bendroflumethiazide	0.7	1.1	4.2	0.2	0.0	-0.0	2.1	1.3	-1.8	0.4	-0.5	0.2
Medication: Paracetamol	0.6	1.0	2.4	-0.3	-1.4	-0.7	-0.9	-0.1	1.0	-1.2	-1.6	-0.8
Medication: Lisinopril	3.0	3.9	7.6	2.8	2.5	2.3	2.1	1.5	-0.7	2.0	-0.8	1.9
Medication: Atorvastatin	0.2	0.3	1.1	0.6	-1.0	0.3	0.4	-0.5	-0.5	-0.3	0.1	-0.1
Illnesses of father: High blood pressure	0.9	1.1	1.8	-1.1	-0.8	-1.2	-0.1	-1.4	0.9	-1.3	-0.5	-1.3
Alcohol drinker status: Never	1.3	1.6	2.7	-1.4	-1.3	-1.6	-1.0	-1.3	0.7	-1.4	0.7	-1.6
Ever smoked	0.2	0.3	0.9	0.9	-0.1	0.8	-0.0	-0.0	0.6	0.5	0.2	0.6
Basal metabolic rate	0.0	0.3	0.8	0.2	-0.3	0.1	0.8	-0.4	0.7	0.3	0.9	0.3
Leg fat percentage (left)	0.6	2.3	17.6	-0.3	0.1	-0.9	4.2	0.7	-1.1	-0.4	-0.6	-0.7
Arm fat-free mass (left)	0.0	0.2	0.6	-0.1	-0.3	-0.2	0.6	-0.6	0.6	-0.0	0.8	0.0
Number of operations (self-reported)	1.0	1.4	5.2	-0.9	-0.3	-0.6	-2.2	-2.3	0.4	-1.0	-0.2	-0.6
Average weekly beer plus cider intake	0.6	0.8	2.6	-0.9	-1.1	-0.8	-1.6	-1.1	0.5	-0.6	-0.0	-0.5
Irritability	1.2	2.1	4.1	2.0	0.7	1.3	1.6	1.2	-1.3	1.3	-1.9	1.2
Risk taking	2.2	3.2	11.0	-1.9	-0.6	-1.7	-2.2	-3.3	1.6	-0.8	0.8	-1.5
Ever had prostate specific antigen (PSA) test	3.0	3.4	6.5	1.9	2.5	2.1	1.4	1.0	-1.4	1.9	-1.2	2.5
Fractured/broken bones in last 5 years	0.2	0.2	1.0	0.1	0.4	-0.5	0.1	-0.4	-0.1	-0.1	-1.0	-0.5
Age started oral contraceptive pill	1.4	1.8	5.0	-1.6	-0.4	-1.0	-1.2	-0.8	2.0	-0.9	2.2	-0.9
Diastolic blood pressure, automated reading	1.2	3.7	7.2	-2.2	-2.5	-2.7	-0.3	-1.5	0.6	-2.5	-0.4	-2.4
Ever depressed for a whole week	0.5	0.7	2.5	0.8	0.1	1.0	-0.9	0.2	0.7	0.2	1.6	0.7
Unable to work because of sickness or disability	0.8	1.1	6.2	-0.0	-1.0	-0.6	0.5	0.5	-1.0	-0.4	-2.5	-0.7
Commuting to job workplace: Cycle	3.1	3.7	6.6	-1.6	-2.5	-1.7	-1.9	-1.4	1.6	-2.6	1.8	-1.9
Myopia	0.8	1.2	5.3	-1.1	-0.9	0.2	-2.3	-1.2	1.1	-0.1	0.9	-0.1
Vascular/heart problems diagnosed by doctor	1.4	3.8	16.8	-1.1	0.2	-0.3	-4.1	-2.8	2.5	-0.9	1.1	-0.5
Cholesterol lowering medication	0.5	0.7	3.4	0.7	0.5	0.5	1.8	0.4	-0.7	0.1	-0.9	0.6
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	4.5	1.1	-0.1	1.1	1.2	0.7	-2.1	0.5	-1.3	0.9
Pain experienced in last month	2.4	3.9	6.5	-2.4	-2.1	-2.4	-1.3	-0.8	1.0	-2.1	2.4	-2.5
Supplements: Calcium	1.2	1.3	3.2	-1.3	-0.2	-1.0	-1.8	-1.5	0.3	-1.1	-1.2	-1.1
Basal cell carcinoma (self-reported)	0.6	0.7	2.0	0.6	1.0	1.4	0.0	0.0	-0.3	1.3	0.6	1.2
Heart attack/myocardial infarction (self-reported)	0.9	1.2	2.9	1.1	-0.8	0.7	1.3	1.7	-0.9	0.5	-1.4	0.8
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.7	-0.2	0.1	-0.4	-0.6	-0.8	0.0	-0.7	0.6	-0.4
Heart disease (siblings)	0.6	0.7	2.9	0.2	1.1	0.0	1.7	-0.1	-0.0	0.2	-1.4	0.1
Alcohol drinker status: Previous	0.4	0.5	1.0	-0.7	-1.0	-0.5	0.4	1.0	-0.7	-0.6	-0.6	-0.4
Pack years of smoking	1.1	1.5	4.8	0.6	-0.6	0.4	1.6	1.8	-2.2	1.1	-0.8	0.7
Impedance of whole body	0.2	0.8	3.1	0.8	0.2	0.7	0.4	1.3	-0.8	0.9	-1.8	0.4
Leg fat mass (left)	0.4	1.4	8.7	-0.6	-0.6	-1.1	3.0	0.1	-0.1	-0.8	0.3	-1.0
Arm predicted mass (left)	0.0	0.2	0.9	0.1	-0.3	-0.0	0.6	-0.6	0.6	0.1	0.9	0.2