[Hub]/) : Traits : Cardiovascular Disease :

chr3:26,563,909-28,211,713

Best TWAS P=1.33e-12 · Best GWAS P=5.34e-15 conditioned to 0.469

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NEK10 0.04 0.03 blup 450 0.03 9.5e-05 3.6 -5.1 2.8e-07 0.57 0.61 0.14 FALSE
2 GTEx Artery Aorta SLC4A7 0.10 0.08 enet 15 0.08 5.4e-05 -7.8 -7.1 1.3e-12 0.92 0.00 0.99 TRUE
3 GTEx Cells Transformed fibroblasts SLC4A7 0.15 0.02 enet 21 0.04 4.0e-04 -7.8 -7.0 2.3e-12 0.80 0.00 0.99 TRUE
4 The Cancer Genome Atlas Breast Invasive Carcinoma NEK10 0.02 0.02 lasso 4 0.02 1.3e-05 -5.4 5.4 8.2e-08 -0.69 0.14 0.86 FALSE
5 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma SLC4A7 0.08 0.02 lasso 4 0.04 1.4e-03 4.2 -6.4 1.5e-10 0.28 0.02 0.30 TRUE