TWAS
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Traits
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Traits
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Cardiovascular Disease
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chr3:10,617,048-12,457,119
Best TWAS P=2.57e-09 · Best GWAS P=3.39e-10 conditioned to 0.0266
11M
11.5M
12M
12.5M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Muscle Skeletal
ATG7
0.06
0.02
lasso
4
0.03
8.6e-04
-5.9
6.0
2.6e-09
-0.87
0.06
0.91
TRUE
2
CommonMind
Brain Pre-frontal Cortex
VGLL4
0.04
0.02
blup
511
0.02
7.8e-04
-6.0
-5.4
6.4e-08
0.81
0.03
0.95
FALSE
1
CommonMind
Brain Pre-frontal Cortex
ATG7
0.07
0.07
lasso
3
0.07
3.3e-09
-4.6
5.3
1.2e-07
-0.83
0.19
0.81
FALSE