Best TWAS P=2.57e-09 · Best GWAS P=3.39e-10 conditioned to 0.0266
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ATG7 | 0.07 | 0.07 | lasso | 3 | 0.07 | 3.3e-09 | -4.6 | 5.3 | 1.2e-07 | -0.83 | 0.19 | 0.81 | FALSE |
| 2 | CommonMind | Brain Pre-frontal Cortex | VGLL4 | 0.04 | 0.02 | blup | 511 | 0.02 | 7.8e-04 | -6.0 | -5.4 | 6.4e-08 | 0.81 | 0.03 | 0.95 | FALSE |
| 3 | GTEx | Muscle Skeletal | ATG7 | 0.06 | 0.02 | lasso | 4 | 0.03 | 8.6e-04 | -5.9 | 6.0 | 2.6e-09 | -0.87 | 0.06 | 0.91 | TRUE |