Best TWAS P=8.48e-10 · Best GWAS P=2.42e-07 conditioned to 0.0909
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | ABCF3 | 0.19 | 0.14 | enet | 20 | 0.16 | 1.8e-22 | 5.2 | 5.9 | 4.2e-09 | 0.88 | 0.00 | 1.00 | FALSE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CAMK2N2 | 0.04 | 0.01 | enet | 8 | 0.03 | 3.9e-04 | 4.3 | 6.1 | 8.5e-10 | 0.63 | 0.02 | 0.75 | TRUE |