Best TWAS P=1.95e-09 · Best GWAS P=2.21e-09 conditioned to 0.000727
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | RGS12 | 0.09 | 0.00 | enet | 21 | 0.02 | 2.1e-02 | 4.9 | 6.0 | 2.0e-09 | 0.40 | 0.06 | 0.55 | TRUE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | RGS12 | 0.21 | 0.24 | enet | 9 | 0.27 | 8.9e-16 | -5.3 | -5.2 | 1.6e-07 | -0.57 | 0.03 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | C4orf44 | 0.03 | 0.02 | blup | 42 | 0.02 | 8.0e-04 | -4.6 | 5.3 | 1.3e-07 | 0.47 | 0.27 | 0.24 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | C4orf44 | 0.03 | 0.04 | lasso | 4 | 0.05 | 2.9e-06 | -4.7 | 5.2 | 2.4e-07 | 0.45 | 0.55 | 0.37 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | RGS12 | 0.08 | 0.01 | blup | 108 | 0.01 | 2.4e-02 | 3.6 | 5.9 | 4.8e-09 | 0.28 | 0.03 | 0.06 | TRUE |