[Hub]/) : Traits : Cardiovascular Disease : ← →

chr1:15,314,120-17,490,832

Best TWAS P=7.89e-10 · Best GWAS P=1.66e-07 conditioned to 0.582

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	ROSMAP	Brain Pre-frontal Cortex	PLEKHM2	0.06	0.01	blup	488	0.03	4.7e-05	-2.8	-6.2	7.9e-10	0.31	0.26	0.09	TRUE
3	GTEx	Pancreas	RP4-798A10.2	0.18	0.01	lasso	6	0.06	1.8e-03	-5.2	-5.5	3.2e-08	0.87	0.01	0.90	TRUE
4	GTEx	Skin Not Sun Exposed Suprapubic	RP11-169K16.9	0.19	0.06	lasso	8	0.06	4.7e-04	-4.5	5.6	2.2e-08	-0.66	0.07	0.88	FALSE
7	ROSMAP	Brain Pre-frontal Cortex	HSPB7	0.18	0.18	lasso	9	0.20	2.2e-25	-5.2	-5.4	5.9e-08	0.96	0.01	0.99	FALSE
1	CommonMind	Brain Pre-frontal Cortex	HSPB7	0.18	0.16	lasso	11	0.15	3.1e-18	-4.7	-5.4	6.8e-08	0.94	0.02	0.98	FALSE
10	The Cancer Genome Atlas	Skin Cutaneous Melanoma	SPEN	0.18	0.03	blup	71	0.00	3.7e-01	5.0	-5.3	1.4e-07	0.80	0.01	0.53	FALSE
9	The Cancer Genome Atlas	Lung Adenocarcinoma	HSPB7	0.08	0.04	lasso	3	0.06	8.0e-08	4.9	-5.2	1.5e-07	0.77	0.02	0.97	FALSE
5	GTEx	Thyroid	HSPB7	0.17	0.12	lasso	6	0.15	9.8e-12	-4.7	-5.2	1.6e-07	0.95	0.02	0.98	FALSE
2	GTEx	Esophagus Mucosa	PLEKHM2	0.10	0.01	enet	20	0.02	1.2e-02	-3.9	5.2	1.8e-07	-0.37	0.35	0.10	FALSE
8	ROSMAP	Brain Pre-frontal Cortex	CLCNKA	0.16	0.18	enet	15	0.21	1.4e-26	4.7	-5.2	2.2e-07	0.93	0.06	0.93	FALSE