Best TWAS P=1.8e-10 · Best GWAS P=1.03e-19 conditioned to 5.74e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | SLC22A3 | 0.15 | 0.05 | lasso | 9 | 0.05 | 0.00099 | 3.1 | 5.2 | 1.5e-07 | 0.06 | 0.74 | 0.02 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | SLC22A1 | 0.04 | 0.00 | bslmm | 534 | 0.01 | 0.01280 | 2.6 | -6.4 | 1.8e-10 | -0.14 | 0.06 | 0.06 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SLC22A1 | 0.04 | 0.01 | enet | 17 | 0.01 | 0.00052 | 5.4 | -5.5 | 2.9e-08 | -0.59 | 0.01 | 0.94 | TRUE |