Best TWAS P=1.37e-08 · Best GWAS P=1.14e-07 conditioned to 0.122
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | ADK | 0.25 | 0.14 | lasso | 9 | 0.12 | 1.6e-06 | 5.0 | 5.2 | 2.1e-07 | 0.90 | 0.02 | 0.97 | FALSE |
| 2 | GTEx | Pancreas | AGAP5 | 0.13 | 0.05 | lasso | 5 | 0.06 | 1.8e-03 | 4.3 | 5.2 | 1.8e-07 | 0.65 | 0.06 | 0.49 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | AP3M1 | 0.02 | 0.01 | blup | 231 | 0.02 | 1.3e-03 | -4.5 | 5.7 | 1.4e-08 | 0.76 | 0.05 | 0.51 | TRUE |