[Hub]/) : Traits : Cardiovascular Disease : ← →

chr10:63,856,856-65,606,229

Best TWAS P=1.97e-16 · Best GWAS P=1.17e-15 conditioned to 0.023

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Muscle Skeletal ADO 0.15 0.16 lasso 8 0.16 1.1e-15 5.5 6.2 4.6e-10 -0.63 1.00 0.00 FALSE
2 GTEx Muscle Skeletal RP11-436D10.3 0.08 0.04 enet 13 0.06 3.2e-06 -7.2 7.2 6.2e-13 -0.73 0.15 0.84 FALSE
3 GTEx Skin Sun Exposed Lower leg NRBF2 0.06 0.01 lasso 3 0.00 4.0e-01 -8.0 8.2 2.0e-16 -0.81 0.02 0.74 TRUE
4 GTEx Testis ADO 0.21 0.23 lasso 7 0.22 6.6e-10 5.5 -5.6 1.9e-08 0.62 0.99 0.01 FALSE
5 METSIM Adipose ADO 0.07 0.00 bslmm 461 0.01 3.4e-02 4.2 5.8 6.8e-09 -0.49 0.09 0.84 FALSE
6 ROSMAP Brain Pre-frontal Cortex ADO 0.06 0.04 lasso 2 0.06 3.1e-08 -7.2 7.2 7.7e-13 -0.83 0.01 0.99 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma ADO 0.03 0.02 blup 53 0.03 1.8e-06 5.2 6.7 1.7e-11 -0.77 0.01 0.99 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ADO 0.10 0.03 enet 6 0.06 4.6e-07 5.6 7.4 9.7e-14 -0.81 0.00 1.00 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma ADO 0.14 0.05 blup 53 0.05 3.8e-06 -8.0 8.1 4.1e-16 -0.82 0.00 1.00 FALSE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma ADO 0.06 0.04 blup 55 0.01 1.4e-01 -7.2 8.0 8.8e-16 -0.83 0.01 0.76 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma ADO 0.12 0.10 lasso 5 0.09 5.2e-09 -7.2 7.5 7.1e-14 -0.86 0.02 0.98 FALSE