[Hub]/) : Traits : Cardiovascular Disease : ← →

chr10:63,856,856-65,606,229

Best TWAS P=1.97e-16 · Best GWAS P=1.17e-15 conditioned to 0.023

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Skin Sun Exposed Lower leg	NRBF2	0.06	0.01	lasso	3	0.00	4.0e-01	-8.0	8.2	2.0e-16	-0.81	0.02	0.74	TRUE
9	The Cancer Genome Atlas	Lung Adenocarcinoma	ADO	0.14	0.05	blup	53	0.05	3.8e-06	-8.0	8.1	4.1e-16	-0.82	0.00	1.00	FALSE
10	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ADO	0.06	0.04	blup	55	0.01	1.4e-01	-7.2	8.0	8.8e-16	-0.83	0.01	0.76	FALSE
11	The Cancer Genome Atlas	Thyroid Carcinoma	ADO	0.12	0.10	lasso	5	0.09	5.2e-09	-7.2	7.5	7.1e-14	-0.86	0.02	0.98	FALSE
8	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ADO	0.10	0.03	enet	6	0.06	4.6e-07	5.6	7.4	9.7e-14	-0.81	0.00	1.00	FALSE
2	GTEx	Muscle Skeletal	RP11-436D10.3	0.08	0.04	enet	13	0.06	3.2e-06	-7.2	7.2	6.2e-13	-0.73	0.15	0.84	FALSE
6	ROSMAP	Brain Pre-frontal Cortex	ADO	0.06	0.04	lasso	2	0.06	3.1e-08	-7.2	7.2	7.7e-13	-0.83	0.01	0.99	FALSE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	ADO	0.03	0.02	blup	53	0.03	1.8e-06	5.2	6.7	1.7e-11	-0.77	0.01	0.99	FALSE
1	GTEx	Muscle Skeletal	ADO	0.15	0.16	lasso	8	0.16	1.1e-15	5.5	6.2	4.6e-10	-0.63	1.00	0.00	FALSE
5	METSIM	Adipose	ADO	0.07	0.00	bslmm	461	0.01	3.4e-02	4.2	5.8	6.8e-09	-0.49	0.09	0.84	FALSE
4	GTEx	Testis	ADO	0.21	0.23	lasso	7	0.22	6.6e-10	5.5	-5.6	1.9e-08	0.62	0.99	0.01	FALSE