Best TWAS P=1.58e-08 · Best GWAS P=1.49e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | MXI1 | 0.07 | 0.08 | enet | 3 | 0.07 | 1.1e-08 | 5.7 | 5.6 | 2.2e-08 | 0.98 | 0.00 | 1.00 | FALSE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | MXI1 | 0.04 | 0.03 | blup | 60 | 0.03 | 1.8e-04 | 4.9 | 5.2 | 1.9e-07 | 0.87 | 0.01 | 0.95 | FALSE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MXI1 | 0.08 | 0.08 | lasso | 2 | 0.08 | 2.4e-09 | 5.7 | 5.7 | 1.6e-08 | 1.00 | 0.00 | 1.00 | TRUE |