TWAS
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Traits
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Traits
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Cardiovascular Disease
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chr10:115,555,541-116,178,891
Best TWAS P=2.94e-15 · Best GWAS P=1.63e-23 conditioned to 4.94e-13
115.6M
115.7M
115.8M
115.9M
116M
116.1M
116.2M
0
5
10
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20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
ADRB1
0.16
0.03
enet
31
0.07
4.1e-08
-10.0
7.9
2.9e-15
-0.60
0.00
0.98
TRUE
2
The Cancer Genome Atlas
Lung Adenocarcinoma
C10orf118
0.03
0.01
blup
42
0.02
1.9e-03
-3.8
6.8
1.5e-11
0.07
0.02
0.26
TRUE