Best TWAS P=2.9e-20 · Best GWAS P=3.81e-35 conditioned to 1.07e-15
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | MASP1 | 0.25 | 0.10 | enet | 28 | 0.16 | 3.8e-12 | 0.5 | -6.6 | 4.9e-11 | -0.54 | 0.43 | 0.54 | FALSE |
| 2 | YFS | Blood | LPP | 0.33 | 0.11 | enet | 26 | 0.22 | 3.2e-70 | -3.2 | 5.2 | 2.1e-07 | 0.08 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | SST | 0.07 | 0.05 | blup | 48 | 0.03 | 1.6e-02 | 10.3 | -9.2 | 2.9e-20 | -0.86 | 0.01 | 0.94 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | RTP2 | 0.11 | 0.08 | enet | 9 | 0.08 | 2.7e-09 | 5.3 | -5.4 | 8.0e-08 | -0.38 | 1.00 | 0.00 | FALSE |