Hub : Genes

CCDC50

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1280 0.0340 7.3e-06 0.084 0.043 0.058 0.082 0.067 2.1e-10 4.9e-06 1.3e-07 3.4e-10 1.4e-08
2 GTEx Adipose Subcutaneous 0.1960 0.0420 7.9e-09 0.160 NA 0.162 NA 0.160 4.4e-13 NA 3.2e-13 NA 4.5e-13
3 GTEx Adipose Visceral Omentum 0.2020 0.0560 3.9e-05 0.139 NA 0.124 NA 0.143 1.1e-07 NA 5.6e-07 NA 7.3e-08
4 GTEx Artery Aorta 0.3430 0.0550 1.6e-13 0.230 NA 0.317 NA 0.320 7.1e-13 NA 5.6e-18 NA 3.7e-18
5 GTEx Artery Coronary 0.3470 0.0850 2.1e-05 0.122 NA 0.127 NA 0.147 6.6e-05 NA 4.6e-05 NA 1.2e-05
6 GTEx Artery Tibial 0.4168 0.0478 0.0e+00 0.420 NA 0.438 NA 0.450 2.0e-35 NA 2.4e-37 NA 9.6e-39
7 GTEx Breast Mammary Tissue 0.1500 0.0490 8.2e-04 0.091 NA 0.119 NA 0.114 2.0e-05 NA 1.1e-06 NA 1.9e-06
8 GTEx Breast Mammary Tissue (Female) 0.1350 0.0667 3.8e-02 -0.003 NA -0.002 NA 0.001 3.9e-01 NA 3.6e-01 NA 2.9e-01
9 GTEx Cells Transformed fibroblasts 0.2020 0.0400 8.4e-12 0.161 NA 0.232 NA 0.232 4.3e-12 NA 2.5e-17 NA 2.1e-17
10 GTEx Colon Sigmoid 0.4500 0.1040 1.7e-04 0.122 NA 0.122 NA 0.087 4.4e-05 NA 4.6e-05 NA 5.3e-04
11 GTEx Colon Transverse 0.1650 0.0590 2.3e-03 0.110 NA 0.086 NA 0.095 6.9e-06 NA 6.8e-05 NA 2.7e-05
12 GTEx Esophagus Gastroesophageal Junction 0.2250 0.0690 2.6e-04 0.158 NA 0.130 NA 0.127 2.4e-06 NA 2.0e-05 NA 2.5e-05
13 GTEx Esophagus Muscularis 0.2900 0.0580 5.2e-10 0.188 NA 0.253 NA 0.254 1.5e-11 NA 1.6e-15 NA 1.3e-15
14 GTEx Heart Atrial Appendage 0.2650 0.0850 2.9e-03 0.050 NA 0.021 NA 0.054 2.8e-03 NA 3.8e-02 NA 1.9e-03
15 GTEx Lung 0.1406 0.0498 1.2e-03 0.019 NA 0.090 NA 0.046 1.3e-02 NA 2.0e-07 NA 2.0e-04
16 GTEx Nerve Tibial 0.3266 0.0545 6.9e-13 0.202 NA 0.231 NA 0.241 2.6e-14 NA 2.4e-16 NA 4.2e-17
17 GTEx Ovary 0.5610 0.1390 6.1e-04 0.191 NA 0.266 NA 0.287 1.9e-05 NA 3.0e-07 NA 9.3e-08
18 GTEx Pancreas 0.3360 0.0610 6.9e-10 0.310 NA 0.307 NA 0.299 1.2e-13 NA 1.6e-13 NA 4.1e-13
19 GTEx Skin Not Sun Exposed Suprapubic 0.2300 0.0710 1.2e-03 0.001 NA 0.001 NA 0.002 2.7e-01 NA 2.6e-01 NA 2.3e-01
20 GTEx Testis 0.4770 0.0770 7.3e-08 0.235 NA 0.310 NA 0.335 8.7e-11 NA 2.8e-14 NA 1.5e-15
21 GTEx Thyroid 0.3890 0.0490 0.0e+00 0.337 NA 0.398 NA 0.397 1.4e-26 NA 2.2e-32 NA 2.6e-32
22 METSIM Adipose 0.0517 0.0161 3.6e-05 0.067 0.035 0.055 0.047 0.062 2.6e-10 5.2e-06 1.2e-08 1.3e-07 1.4e-09
23 YFS Blood 0.0379 0.0124 1.9e-05 0.006 0.016 0.010 0.016 0.013 2.7e-03 3.3e-06 1.6e-04 3.3e-06 2.1e-05
24 TCGA Breast Invasive Carcinoma 0.0775 0.0385 2.7e-05 0.022 0.016 0.016 NA 0.031 2.0e-05 2.3e-04 2.3e-04 NA 5.3e-07
25 TCGA Kidney Renal Clear Cell Carcinoma 0.0521 0.0264 3.0e-04 0.007 0.021 0.022 NA 0.031 5.0e-02 1.6e-03 1.5e-03 NA 1.7e-04
26 TCGA Kidney Renal Papillary Cell Carcinoma 0.2190 0.0710 3.0e-10 0.170 0.066 0.180 NA 0.156 5.3e-10 1.3e-04 1.6e-10 NA 2.9e-09
27 TCGA Thyroid Carcinoma 0.0670 0.0280 3.7e-07 0.092 0.072 0.075 NA 0.079 3.1e-09 1.6e-07 9.4e-08 NA 4.2e-08

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bipolar Disorder (2018) 0.9 1.4 9.8 0.7 0.7 0.5 0.9 1.1 0.9 0.1 -0.7 -1.4 -1.1 -0.1 0.8 0.9 -1.1 -2.5 0.5 -1.0 0.2 -1.7 3.1 0.6 0.6 1.2 1.0 1.5 0.8 0.7
Bipolar Disorder or Schizophrenia 0.6 1.6 5.5 -0.7 0.6 -0.1 0.7 0.1 0.2 -1.2 -1.1 -2.2 -1.2 -0.2 0.6 0.3 -2.0 -2.0 0.2 -1.3 0.3 -1.4 2.3 0.5 1.9 0.2 -0.8 1.4 2.2 1.7
Depressed Affect (Nagel 2018) 1.5 3.1 6.7 -1.3 -2.1 -2.1 -1.8 -1.9 -1.8 -2.3 -2.5 1.5 -1.1 -2.3 -2.1 -1.8 -1.1 -2.6 -1.7 -2.2 -2.1 -1.3 -0.0 -2.0 -1.6 -0.7 0.7 -0.7 -1.6 -1.8
Depression (Nagel 2018) 0.3 0.5 1.7 0.0 -0.9 -0.5 -0.4 -0.4 -0.5 -0.9 -1.3 0.9 0.1 -0.5 -0.5 -0.3 0.3 -0.5 -0.5 -0.3 -1.2 0.2 -0.8 -0.7 -1.0 -1.2 -0.9 -0.2 -0.8 -1.0
Intelligence (Savage-Jansen 2018) 0.4 1.3 3.1 1.1 1.0 1.2 1.1 1.3 1.3 1.5 1.1 -0.7 1.0 1.1 1.3 1.2 1.6 1.4 1.3 1.7 1.0 0.5 0.5 1.3 0.5 1.8 1.6 -0.1 -0.1 0.6
Neuroticism (Nagel 2018) 1.7 4.0 7.8 -1.7 -2.3 -2.3 -2.3 -2.4 -2.1 -1.9 -2.3 2.4 -1.2 -2.3 -2.6 -2.1 -0.8 -1.1 -2.1 -2.0 -2.8 -0.8 -1.2 -2.6 -2.4 -1.2 -0.5 -0.7 -2.3 -2.6
Schizophrenia (2018) 0.5 1.1 4.5 -1.5 0.3 -0.5 0.2 -0.7 -0.5 -1.6 -0.8 -1.7 -0.7 -0.2 0.2 -0.4 -1.7 -0.5 -0.2 -0.9 0.2 -0.4 0.5 0.1 1.9 -0.7 -1.8 0.6 2.1 1.7
Schizophrenia vs Biploar Disorder 0.4 0.5 4.7 0.6 0.4 -0.1 -0.4 -0.4 0.0 0.1 0.4 0.0 0.8 -0.2 0.3 -0.3 0.8 1.3 -0.2 1.1 0.7 2.2 -0.2 0.2 -0.2 0.1 -0.1 -1.6 -0.4 -0.2
Worry (Nagel 2018) 1.2 2.6 6.5 -2.1 -1.8 -1.7 -1.4 -2.0 -1.6 -1.2 -1.7 1.8 -1.0 -1.0 -1.8 -1.1 -1.0 0.0 -1.1 -1.9 -2.1 -1.3 -1.5 -2.0 -1.8 -1.5 -2.6 0.2 -1.8 -1.9
Alzheimer’s Disease (in mother) 2.1 2.5 10.7 -3.3 -1.8 -1.9 -1.5 -1.9 -1.9 -1.2 -0.6 0.4 -1.9 -1.7 -1.0 -1.7 -2.2 -1.3 -1.8 -2.5 -0.7 -2.1 1.1 -1.3 -0.8 0.7 -0.9 0.3 -1.1 -0.9
Alzheimer’s Disease (in father) 0.9 0.9 2.1 1.0 -1.2 -0.8 -0.8 -0.4 -0.4 -0.9 -0.8 1.0 -1.3 -1.4 -1.1 -0.6 -0.8 -1.3 -0.7 -1.0 -0.9 -0.6 0.4 -1.2 -1.2 -0.7 0.3 -1.4 -1.1 -1.2
Alzheimer’s Disease (including proxy) 0.6 0.9 4.2 -1.5 -0.9 -0.9 -0.4 -0.7 -0.7 -0.5 0.1 -0.1 -1.4 -0.9 -0.4 -0.5 -1.7 -1.1 -0.6 -1.8 -0.1 -2.0 1.5 -0.8 -0.3 0.6 -0.5 0.5 -0.3 -0.3
Crohns Disease (2017) 0.2 0.4 2.6 -1.6 -0.3 -0.4 -0.5 -0.4 -0.5 -1.3 -0.8 -0.1 -0.7 -0.3 -0.3 -0.6 -0.4 -0.3 -0.7 -0.0 0.2 0.2 0.4 0.1 -0.3 -0.9 0.1 -1.5 -0.6 -0.2
Irritable Bowel Disease (IBD) 1.1 2.6 5.6 0.9 2.3 2.1 2.0 1.9 1.8 1.5 1.5 -1.7 2.0 2.4 1.6 1.9 1.3 0.6 1.8 1.9 1.9 0.9 0.4 2.2 1.4 0.6 -0.8 0.8 1.4 1.7
Ulcerative Colitis (UC) 4.4 8.3 15.7 2.8 3.5 3.7 3.6 3.3 3.3 3.3 2.9 -2.5 3.6 4.0 2.8 3.6 2.5 1.7 3.6 3.1 2.8 1.1 0.3 3.4 2.3 1.5 -1.1 2.4 2.6 2.7
Major Depression (MDD) 0.6 0.7 4.6 -0.5 -0.6 -1.0 -0.6 -0.9 -0.8 -0.4 -0.3 0.2 -0.8 -1.0 -0.7 -0.8 -1.2 -1.7 -0.8 -1.1 -0.0 -0.7 0.5 -1.0 0.1 -2.1 0.4 -0.6 0.3 -0.4
Reaction Time 0.6 1.2 7.8 -0.8 1.1 0.8 0.6 0.5 0.3 0.9 0.9 -1.5 -0.0 0.8 0.3 0.2 -0.8 1.2 0.6 0.2 2.0 1.1 0.4 1.2 1.6 -0.5 -2.8 0.5 0.9 1.5
Verbal and Numeric Reasoning (VNR) 0.2 0.4 2.3 1.1 0.5 0.4 0.3 0.4 0.4 0.5 0.2 0.3 0.2 0.4 0.2 0.4 1.3 1.0 0.7 0.8 -0.2 -0.4 -0.4 0.2 -0.2 0.8 1.5 -0.3 -0.3 -0.2
Breast Cancer 0.5 1.1 2.9 -1.7 -1.1 -0.9 -1.1 -0.9 -1.3 -1.2 -1.4 1.2 -1.4 -0.7 -1.4 -1.1 0.1 0.4 -1.0 -0.7 -1.1 -1.0 -1.2 -0.9 -1.0 -0.8 1.1 -0.2 -0.9 -1.0
Ovarian Cancer 0.3 0.4 4.9 -0.5 0.1 -0.2 -0.2 -0.4 -0.5 -0.6 -0.6 -0.3 0.4 -0.2 -0.5 -0.6 -0.6 2.2 -0.1 -0.4 -0.1 0.3 -0.7 -0.2 0.8 0.0 -0.3 -0.1 0.8 0.6
Prostate Cancer 0.8 1.1 2.5 0.4 0.8 1.1 1.1 1.1 1.1 1.6 1.0 -1.0 1.3 1.4 1.1 1.1 1.1 0.4 1.0 1.5 1.4 1.0 0.1 1.5 0.6 -0.0 -0.7 1.1 0.2 0.8
Age at First Birth 0.3 0.5 2.2 -0.8 0.4 0.2 0.2 0.0 -0.0 -0.3 -0.4 -1.0 0.1 0.0 0.2 -0.1 -1.4 -0.7 0.1 -0.7 0.3 -0.4 1.0 0.3 0.9 1.1 -1.5 0.6 0.8 0.9
Bipolar Disorder (2011) 1.4 1.3 9.7 -0.5 0.1 -0.1 0.4 0.5 0.4 -0.6 -1.0 -1.6 -0.7 -0.5 0.9 0.2 0.0 -2.9 -0.0 -1.9 0.4 -2.0 3.1 0.1 1.0 -0.2 0.0 0.5 1.2 1.1
Body Mass Index (BMI) (2010) 1.3 1.8 4.0 1.4 2.0 1.3 1.6 1.4 1.4 1.4 0.8 -1.7 0.3 1.4 1.3 1.4 0.1 -0.4 1.5 0.5 1.3 -1.1 1.0 1.4 1.7 0.4 1.9 1.3 1.5 1.7
Coronary Artery Disease (CAD) 0.9 1.0 2.9 1.7 1.1 1.3 0.8 1.7 1.3 0.8 0.1 -0.5 0.8 0.9 1.3 1.0 0.9 -0.1 0.9 1.4 1.0 1.0 0.9 1.4 0.2 0.1 1.6 -0.4 0.1 0.5
Crohns Disease (2012) 0.3 0.5 4.6 -1.1 0.1 -0.4 -0.2 -0.3 -0.3 -1.0 -1.0 -0.3 -2.1 -0.1 -0.0 -0.3 -0.5 -0.8 -0.6 -0.2 0.1 -0.4 0.4 0.1 0.1 -1.1 1.0 -0.5 0.0 0.1
Mean Putamen Volume 0.8 0.9 3.4 1.4 0.8 0.8 0.7 0.8 0.9 1.3 1.9 -0.9 0.9 0.6 0.7 0.6 0.2 -1.3 0.7 1.1 1.5 1.0 0.6 0.7 0.9 0.2 0.3 -0.6 0.8 0.9
Fasting Glucose 0.5 0.6 1.6 0.3 1.1 0.3 0.7 0.5 0.5 1.1 1.0 -1.1 -0.2 0.4 0.3 0.6 -1.0 -0.6 0.3 -0.5 0.4 -1.3 1.2 0.4 0.9 0.5 -0.0 1.3 1.1 0.9
HbA1C 1.2 1.3 5.6 1.5 1.2 1.2 0.9 1.2 1.4 1.2 2.4 -0.6 0.7 1.1 1.2 1.0 0.7 -0.4 0.9 1.4 1.0 0.6 0.4 1.0 0.8 1.5 2.0 0.2 0.5 0.9
HDL Cholesterol 0.5 0.8 5.8 -1.5 -0.9 -0.6 -0.3 -0.8 -0.7 -1.4 -0.7 0.6 -0.8 -0.1 -0.4 -0.4 -0.4 1.2 -0.2 -0.7 -1.2 -0.1 -1.0 -0.7 -0.4 -0.6 -2.4 0.7 -0.3 -0.4
LDL Cholesterol 0.5 0.7 3.1 0.7 -0.8 0.0 -0.4 0.3 0.3 -0.1 0.4 0.9 0.0 -0.3 0.2 0.0 1.0 0.4 -0.1 0.7 -0.3 1.6 0.6 0.0 -1.6 -1.0 -1.7 -0.8 -1.7 -1.5
Lupus 0.6 0.9 2.3 -0.1 -1.0 -0.8 -1.2 -0.8 -0.8 -0.7 -1.2 0.8 -1.5 -1.2 -1.2 -1.1 -0.3 -0.7 -1.0 -0.5 -0.9 0.4 0.4 -0.8 -1.1 -0.2 0.1 -1.4 -1.3 -1.1
Neuroticism (2016) 2.0 2.9 5.1 -1.7 -1.5 -1.8 -2.2 -1.9 -2.1 -1.2 -0.4 2.1 -0.9 -1.8 -2.0 -2.1 -0.7 -1.8 -2.1 -1.0 -1.2 -0.0 -1.9 -1.8 -1.9 -2.0 0.5 -2.2 -1.8 -1.9
Primary Biliary Cirrhosis 1.4 2.0 5.4 -0.7 -2.2 -1.5 -1.2 -1.0 -1.0 -1.5 -2.0 1.5 -0.2 -1.7 -1.0 -0.9 0.3 -1.7 -1.1 -1.0 -1.7 -1.5 0.3 -1.5 -1.8 -0.9 2.3 -0.8 -1.8 -1.9
Rheumatoid Arthritis 0.4 0.5 2.9 -0.5 0.2 -0.3 -0.3 -0.0 -0.1 0.4 0.2 -0.7 0.5 -0.6 0.6 -0.4 -1.7 -1.4 -0.3 -0.9 1.2 -0.4 1.6 0.0 0.3 -0.6 0.9 -0.4 0.1 0.3
Schizophrenia (2014) 0.6 1.4 6.3 0.8 1.4 0.7 1.4 0.8 0.9 -0.4 0.1 -2.1 0.1 0.6 1.4 1.0 -0.7 -1.2 1.0 0.0 0.8 -0.2 1.4 0.9 2.0 0.4 -0.7 1.0 2.5 1.9
Triglycerides 0.2 0.3 0.8 -0.4 -0.4 -0.7 -0.7 -0.5 -0.7 0.1 0.2 0.1 -0.6 -0.9 -0.7 -0.8 -0.7 -0.2 -0.9 -0.6 0.0 -0.1 0.0 -0.5 0.3 0.3 0.6 -0.2 0.2 0.1
Type 2 Diabetes (T2D) (2012) 0.6 0.7 7.7 0.3 0.0 0.3 0.3 0.6 0.4 -0.1 -0.3 -0.8 0.7 0.1 0.9 0.3 -0.2 -2.8 0.2 0.3 0.5 -0.4 1.5 0.7 0.3 0.8 2.0 0.0 0.5 0.6
Ulcerative Colitis 4.7 6.8 12.6 2.4 3.3 3.3 3.2 3.0 2.8 3.2 2.8 -2.4 3.4 3.5 2.5 3.0 1.7 1.0 2.9 2.6 2.8 0.4 0.3 3.0 2.6 1.6 -0.4 2.2 2.9 2.8
Blood Eosinophil Count 0.1 1.1 4.7 0.1 -1.1 -1.0 -1.3 -0.7 -0.7 -0.8 -0.7 1.3 -0.5 -1.4 -0.4 -0.9 0.3 -1.1 -1.1 -0.1 -0.7 0.6 0.6 -0.9 -1.8 0.0 0.5 -2.2 -1.9 -1.8
Blood Platelet Count 0.1 0.8 5.4 -2.3 -0.6 -1.2 -0.5 -1.6 -1.2 -1.0 -0.6 -0.0 -1.1 -0.3 -0.8 -0.8 -0.7 0.4 -0.5 -1.0 -0.9 -1.0 -0.4 -0.8 0.3 -0.1 -0.1 0.9 0.2 0.0
Blood Red Count 0.3 3.0 6.1 -1.7 -1.9 -2.1 -1.6 -2.0 -1.9 -1.8 -2.2 1.5 -1.1 -1.8 -1.9 -1.6 -0.8 -2.5 -1.7 -2.3 -2.1 -2.1 -1.0 -2.2 -1.2 -1.6 1.1 -0.0 -0.9 -1.4
Blood White Count 0.5 4.0 7.4 -1.8 -2.6 -2.7 -2.0 -2.5 -2.1 -1.8 -1.8 2.0 -2.4 -2.4 -1.8 -1.8 -1.2 -1.1 -1.9 -2.5 -2.3 -2.3 0.3 -2.6 -2.4 -0.9 0.4 -0.8 -1.9 -2.5
Heel T-Score 0.1 1.0 5.6 2.4 1.0 0.8 0.3 1.2 0.9 -0.7 -1.3 -1.0 -0.5 -0.3 0.2 0.3 -0.5 -1.1 0.3 0.1 0.4 0.2 1.6 0.9 0.6 0.6 2.3 -1.0 0.6 0.8
BMI 0.9 5.3 14.7 2.0 2.3 2.1 2.7 2.4 2.3 1.9 0.8 -3.8 1.2 1.7 2.1 2.1 -1.1 -1.5 2.1 0.1 2.6 -1.9 3.2 2.3 3.5 1.6 1.2 2.1 3.4 3.5
Height 1.9 36.8 61.2 -6.0 -7.1 -7.4 -7.7 -7.2 -7.6 -7.5 -5.7 6.5 -4.5 -7.3 -6.1 -7.6 -4.1 -2.3 -7.8 -6.2 -6.3 -2.4 -4.5 -7.2 -5.9 -3.9 1.3 -4.9 -5.5 -6.3
Waist Hip Ratio (WHR) 0.8 3.8 11.2 -1.1 -3.2 -1.9 -2.1 -1.8 -1.7 -1.9 -1.4 3.1 -1.1 -1.8 -1.7 -1.6 0.7 -0.2 -1.6 -0.9 -2.6 -0.5 -1.4 -2.1 -3.4 -1.2 0.8 -1.2 -2.9 -3.2
Systolic Blood Pressure 0.1 0.6 5.1 -0.4 -0.8 -0.1 0.5 0.2 0.3 -1.0 -0.4 -0.4 0.0 -0.1 0.5 0.6 -1.1 -0.1 0.5 -1.2 -0.1 -1.9 2.3 -0.1 -0.4 -0.1 -0.6 0.8 -0.7 -0.3
Smoking Status 1.3 3.1 8.1 -0.1 -2.2 -1.9 -2.2 -1.6 -1.6 -1.4 -0.6 2.8 -0.5 -2.3 -1.5 -1.8 0.9 -0.1 -2.0 -0.0 -2.0 1.3 -1.1 -2.1 -2.8 -0.6 0.3 -2.3 -2.5 -2.8
Allergy or Eczema 0.3 0.8 7.7 -1.0 0.2 -0.0 -0.5 -0.1 -0.3 -0.2 -0.5 0.1 -0.8 -0.1 -0.5 -0.4 -0.5 1.6 -0.4 -0.1 0.9 1.7 -0.4 0.3 -0.3 -0.6 -2.8 -1.2 -1.1 -0.2
Cardiovascular Disease 0.1 0.3 1.7 -0.3 -0.4 -0.5 -0.1 -0.4 -0.4 -0.8 -0.9 -0.3 -1.0 -0.3 -0.6 -0.2 -0.5 -0.3 -0.1 -0.8 -0.2 -1.3 0.4 -0.2 0.1 -0.5 1.1 0.5 0.2 0.0
Hypothyroidism (self reported) 1.5 3.5 11.2 1.4 -1.7 -0.9 -1.9 -0.3 -0.6 -1.0 -0.6 2.9 -0.4 -1.7 -1.1 -1.1 2.4 -1.9 -1.5 1.0 -1.4 2.0 -1.0 -1.1 -3.3 -0.6 3.3 -3.0 -3.1 -3.0
Respiratory disease 2.0 4.5 8.5 -1.4 -2.2 -2.7 -2.4 -2.3 -2.2 -2.2 -2.6 2.0 -2.8 -2.9 -2.3 -2.2 -1.4 -1.2 -2.3 -2.6 -2.5 -1.4 0.2 -2.8 -2.2 -0.9 0.6 -1.5 -2.0 -2.3
Type 2 Diabetes (T2D) (2018) 0.1 0.2 0.8 -0.8 -0.6 -0.4 -0.4 -0.5 -0.4 -0.6 0.2 -0.2 -0.2 -0.2 0.3 -0.4 -0.6 0.8 -0.3 -0.4 0.5 -0.2 0.3 0.1 -0.2 -0.5 -0.9 0.2 -0.6 -0.2
Lung FEV1/FVC ratio 0.7 3.7 12.5 0.0 2.3 1.7 2.0 1.7 1.4 0.8 0.7 -3.2 1.7 1.7 2.0 1.3 -1.3 -1.2 1.6 0.3 2.2 -1.0 1.7 2.0 3.5 0.3 1.0 1.8 3.5 3.4
Lung FVC 1.2 5.9 12.8 1.8 3.0 3.3 2.5 3.3 2.7 2.5 1.7 -2.3 1.4 3.0 1.6 2.5 1.8 3.3 2.7 3.2 2.8 2.5 0.7 3.6 2.2 0.9 -0.8 1.4 1.8 2.6
Neuroticism 2.0 4.9 8.0 -2.2 -2.4 -2.5 -2.7 -2.7 -2.5 -2.3 -2.4 2.6 -1.5 -2.5 -2.8 -2.5 -0.9 -0.7 -2.4 -1.9 -2.5 -0.1 -1.4 -2.6 -2.5 -2.0 -1.2 -1.6 -2.6 -2.7
Chronotype (morning person) 0.3 0.6 4.5 -0.6 0.1 -0.1 -0.7 -0.1 -0.6 0.1 -0.4 -0.7 -1.3 -0.5 -0.4 -1.0 -2.1 -0.1 -0.7 -0.7 0.9 -0.0 0.1 0.3 0.9 -1.2 -0.3 -1.4 0.5 0.9
Hair Pigment 0.1 1.6 6.1 0.2 1.0 1.5 1.6 1.4 1.2 1.1 0.6 -1.3 1.4 1.7 1.3 1.5 0.5 -0.2 1.6 0.5 0.7 -1.2 0.3 1.4 1.2 1.6 1.1 2.5 1.0 1.3
Tanning 0.1 1.0 6.0 1.2 0.8 0.8 0.5 1.2 0.9 0.7 1.2 -0.2 0.7 0.4 0.6 0.8 1.9 0.5 0.6 1.8 0.3 1.1 0.6 0.8 0.2 0.9 2.5 -0.5 -0.1 0.3
Hand grip strength (left) 0.1 0.2 1.1 -0.7 -0.2 -0.3 -0.1 -0.4 -0.2 -0.7 -1.0 -0.1 -0.1 -0.1 -0.1 -0.2 -0.1 0.1 -0.1 -0.4 -0.5 -0.5 0.4 -0.1 -0.0 0.9 0.7 -0.1 -0.3 0.0
Number of treatments/medications taken 1.1 2.0 3.8 -1.0 -2.0 -1.6 -1.5 -1.2 -1.4 -1.4 -1.4 1.7 -0.4 -1.5 -1.5 -1.2 0.5 -1.7 -1.4 -0.8 -1.5 -0.8 -0.4 -1.5 -1.9 -1.9 1.7 -1.0 -1.8 -2.0
Average weekly spirits intake 0.5 0.7 1.7 -0.5 -0.7 -0.9 -0.7 -0.7 -0.7 -0.1 -1.2 0.6 -1.2 -1.1 -0.8 -0.8 -0.9 -1.1 -0.7 -1.3 -0.7 -0.8 0.7 -1.0 -0.5 -0.5 0.8 -0.5 -0.7 -0.6
Sensitivity / hurt feelings 2.7 4.7 9.7 -1.7 -1.8 -2.5 -2.5 -2.6 -2.6 -2.4 -2.8 2.5 -1.4 -2.5 -3.1 -2.5 -0.5 -0.9 -2.5 -1.7 -2.9 -0.1 -2.0 -2.6 -2.1 -2.4 0.3 -1.4 -1.7 -2.3
Frequency of depressed mood in last 2 weeks 0.5 0.7 1.4 -0.5 -1.0 -0.9 -1.0 -1.0 -0.9 -0.8 -0.9 0.9 -0.4 -0.9 -1.0 -0.9 -0.1 -0.4 -1.0 -0.5 -0.7 0.0 -0.6 -0.8 -1.1 -0.7 -0.5 -0.7 -1.2 -1.1
Hearing difficulty/problems: Yes 0.3 0.5 2.3 0.7 -0.1 -0.3 -0.3 -0.3 -0.0 0.3 0.0 1.3 0.4 -0.2 -0.3 0.1 0.8 0.8 0.0 0.2 -0.8 0.2 -0.7 -0.8 -1.4 -1.5 -0.1 0.1 -1.2 -1.4
Relative age of first facial hair 0.5 1.0 4.1 -0.0 -0.8 -0.1 -0.2 -0.1 -0.2 -0.7 -0.9 1.7 0.0 0.3 -0.3 0.2 2.0 0.0 0.0 0.6 -1.3 0.3 -1.8 -0.4 -1.8 -0.8 -1.5 -0.4 -1.7 -1.6
Other serious medical condition/disability diagnosed by doctor 3.2 4.2 8.8 -1.0 -2.4 -2.1 -2.4 -1.9 -1.8 -2.2 -2.0 2.9 -0.5 -2.3 -1.9 -1.9 0.7 -1.5 -2.2 -0.5 -2.4 0.3 -1.1 -2.3 -3.0 -1.6 1.7 -2.7 -3.0 -3.0
Ever used hormone-replacement therapy (HRT) 3.5 4.4 7.8 -2.1 -2.5 -2.5 -2.7 -2.5 -2.6 -1.7 -0.8 2.5 -1.7 -2.3 -2.8 -2.7 -0.3 -2.0 -2.8 -0.9 -2.2 0.1 -2.3 -2.5 -1.9 -1.6 1.9 -1.7 -1.9 -2.1
Ever had hysterectomy (womb removed) 0.5 0.5 3.6 0.2 -0.3 -0.3 -0.8 0.1 -0.3 0.5 0.7 0.8 0.5 -0.8 -0.5 -0.6 1.1 -0.6 -0.4 0.5 -0.1 0.7 0.2 -0.3 -1.0 -0.1 1.9 -1.2 -1.0 -0.9
Systolic blood pressure, automated reading 0.1 0.4 3.5 0.2 -0.5 0.1 0.5 0.3 0.4 -0.5 -0.7 -0.0 -0.3 0.2 0.1 0.6 -0.6 0.4 0.6 -0.7 -0.3 -1.9 1.4 -0.1 -0.4 -0.1 0.3 0.3 -0.5 -0.3
Eye problems/disorders: Diabetes related eye disease 0.7 0.8 3.4 0.4 0.8 0.3 0.7 0.5 0.7 0.4 0.0 -1.3 -0.1 0.3 0.9 0.6 -1.1 -1.1 0.3 -0.5 0.9 -0.1 1.8 0.6 0.8 -1.2 -1.8 0.9 1.1 0.8
Angina 0.7 0.9 3.3 1.4 0.3 1.3 1.1 1.4 1.2 0.5 -0.0 0.4 1.3 1.2 0.8 1.5 1.8 1.3 1.4 1.1 0.2 0.2 -0.1 0.7 -0.6 1.1 0.2 -0.4 -0.6 -0.4
Medication for hormone replacement therapy 1.7 1.8 4.2 -1.3 -1.6 -1.9 -1.5 -1.9 -1.6 -0.9 -0.2 1.5 -1.2 -1.3 -1.4 -1.5 0.1 -1.6 -1.6 -0.7 -1.5 -0.8 -1.4 -1.8 -1.1 -1.0 2.0 -0.8 -0.7 -1.3
Vitamin and mineral supplements 1.4 1.9 6.9 1.5 0.8 1.6 2.0 1.6 1.6 1.1 1.3 -0.8 2.6 2.1 1.8 2.0 1.0 0.7 2.1 1.0 1.0 -0.6 -0.3 1.2 0.9 -0.2 0.4 1.5 1.3 1.0
Supplements: Zinc 0.4 0.4 1.2 -0.8 -0.7 -0.7 -0.7 -0.5 -0.5 -0.3 -0.0 0.5 -0.6 -0.8 -0.6 -0.6 -0.1 0.9 -0.7 -0.2 -0.2 0.5 0.5 -0.5 -0.7 -0.4 -1.1 -1.0 -0.9 -0.7
Medication: Co-codamol 0.9 1.1 3.4 1.8 1.2 1.3 0.6 1.2 1.2 1.0 1.1 -0.1 1.1 1.1 0.9 0.9 1.0 0.9 1.0 1.7 1.3 1.4 -0.0 1.2 -0.1 0.3 0.8 -1.0 -0.4 0.1
Medication: Metformin 0.5 0.7 3.7 -0.3 -1.0 -1.1 -1.1 -1.0 -1.1 -0.8 -0.8 0.4 -0.2 -1.4 -0.6 -1.3 -0.9 -1.9 -1.1 -0.7 -0.8 -0.3 0.0 -0.9 -0.3 -0.2 0.7 -0.6 -0.1 -0.4
Diabetes (father) 0.3 0.3 1.3 -0.7 -0.9 -0.4 -0.2 -0.4 -0.4 -0.6 -0.6 0.7 -1.1 -0.1 -0.2 -0.0 -0.0 0.3 -0.4 -0.6 -0.5 -0.9 -0.8 -0.6 -0.7 -0.7 -0.7 -0.1 -0.4 -0.7
Diabetes (mother) 0.5 0.6 3.8 1.4 0.8 0.6 0.4 0.7 0.8 -0.4 -0.1 -0.9 0.8 0.3 0.6 0.5 0.0 -1.9 0.3 0.6 0.8 0.9 0.8 0.8 0.6 -0.8 0.7 -0.4 0.7 0.7
Severe depression (siblings) 3.9 4.3 7.4 -1.6 -2.5 -2.4 -2.4 -2.5 -2.4 -2.7 -2.2 2.7 -1.4 -2.1 -2.3 -2.2 0.3 0.9 -2.0 -1.2 -2.1 0.3 -2.1 -2.4 -2.4 -2.1 -0.3 -2.0 -2.4 -2.6
Pack years adult smoking proportion 1.4 2.1 10.6 -2.2 -1.5 -1.2 -0.4 -0.8 -1.0 -1.1 -1.3 -0.2 -1.2 -1.1 -0.4 -0.7 -2.1 -3.2 -0.7 -2.5 -1.2 -3.1 1.5 -1.2 0.3 -1.3 0.2 1.1 0.7 0.1
Impedance of leg (right) 1.6 7.9 14.3 -3.8 -3.3 -3.4 -3.5 -3.6 -3.6 -3.2 -2.5 3.4 -1.5 -2.9 -2.9 -3.3 -1.1 0.1 -3.4 -2.3 -3.1 0.2 -3.1 -3.3 -2.9 -2.2 -1.2 -1.3 -2.6 -3.1
Leg fat-free mass (left) 0.2 0.9 5.6 0.3 -0.5 -0.4 -0.1 0.0 -0.1 -0.6 -0.4 -0.8 0.1 -0.8 0.4 -0.4 -1.3 -2.0 -0.4 -1.1 0.2 -2.2 1.9 -0.2 0.3 0.3 2.4 -0.6 0.4 0.3
Trunk fat percentage 0.2 0.7 2.0 -0.6 -1.0 -0.8 -1.1 -0.7 -1.0 -1.0 -0.8 0.5 0.7 -1.0 -0.4 -1.2 -0.6 -0.7 -0.9 -0.5 -0.1 -0.2 -0.3 -0.6 -0.5 -1.1 1.3 -1.4 -0.8 -0.5
Hand grip strength (right) 0.1 0.3 2.3 -1.1 -0.3 -0.2 0.0 -0.4 -0.2 -0.8 -1.5 -0.3 -0.3 -0.1 -0.0 -0.1 -0.7 0.5 -0.1 -1.0 -0.2 -1.2 0.6 -0.1 0.2 0.6 0.0 -0.2 -0.2 0.2
Townsend deprivation index at recruitment 1.1 1.5 9.2 2.6 1.1 1.0 0.4 1.2 1.1 1.1 1.3 -0.2 0.7 0.4 1.0 0.6 1.3 -3.0 0.3 1.8 1.3 2.2 0.5 1.0 0.1 -0.2 1.3 -1.1 0.1 0.2
Current tobacco smoking 0.4 0.6 2.6 -0.1 -1.3 -0.5 -0.4 -0.2 -0.4 -0.1 -0.2 1.6 0.5 -0.4 -0.1 -0.1 1.2 -0.2 -0.3 0.1 -1.5 -0.3 -1.0 -0.9 -1.4 -0.4 -0.2 0.3 -1.0 -1.4
Average weekly fortified wine intake 0.3 0.3 1.7 -1.1 -0.4 -0.4 -0.5 -0.3 -0.3 -0.8 -1.0 0.4 -0.6 -0.4 -0.4 -0.4 -0.3 -0.1 -0.6 -0.4 -0.3 0.6 0.3 -0.2 -0.6 -0.4 -1.3 -0.2 -1.0 -0.5
Maternal smoking around birth 0.5 0.8 3.4 0.7 -0.8 -0.4 -0.6 -0.6 -0.4 -0.2 0.2 1.7 -0.6 -0.2 -0.3 -0.3 1.0 0.6 -0.3 0.5 -1.3 0.3 -1.9 -1.0 -1.4 -0.5 0.4 -0.6 -1.7 -1.4
Fed-up feelings 0.5 0.9 5.1 -0.8 -0.8 -0.8 -1.0 -0.9 -0.8 -0.9 -0.6 1.0 0.4 -0.8 -0.8 -0.9 0.2 -2.3 -0.8 -0.1 -0.5 0.5 -0.6 -0.7 -1.1 -1.6 -0.4 -1.4 -1.2 -1.2
Frequency of unenthusiasm / disinterest in last 2 weeks 1.9 2.5 5.7 -1.1 -1.6 -1.8 -1.6 -1.8 -1.6 -1.9 -2.1 1.4 -1.2 -1.8 -1.5 -1.5 -0.3 -2.4 -1.8 -1.3 -1.7 0.2 -0.8 -1.7 -1.5 -2.4 -1.4 -1.0 -1.5 -1.6
Relative age voice broke 0.3 0.5 1.3 -0.9 -0.7 -0.7 -0.3 -0.6 -0.6 -0.7 -0.9 0.8 -1.2 -0.3 -0.3 -0.3 -0.2 0.1 -0.4 -0.8 -1.1 -0.9 -0.7 -0.8 -0.7 -0.5 -0.9 0.2 -0.5 -0.7
Taking other prescription medications 1.0 1.6 4.3 -0.3 -1.6 -1.4 -1.3 -1.2 -1.1 -1.6 -1.7 1.5 -0.1 -1.3 -1.3 -1.0 0.5 -0.9 -1.1 -0.4 -1.4 0.1 -0.2 -1.3 -1.7 -2.1 0.9 -1.5 -1.7 -1.8
Age when periods started (menarche) 0.3 0.8 4.7 -1.0 0.9 -0.3 -0.1 -0.5 -0.5 0.6 0.8 -1.4 -0.6 -0.1 -0.1 -0.7 -2.2 0.1 -0.6 -0.8 1.2 -0.1 -0.3 0.2 1.8 -0.2 -0.3 -0.1 1.7 1.6
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 2.7 0.2 -0.9 -0.5 -0.9 -0.4 -0.7 -0.3 0.3 1.2 0.4 -0.6 -0.7 -0.8 0.8 -0.1 -0.5 0.4 -0.7 0.2 -0.8 -0.5 -1.2 0.6 1.6 -0.9 -1.1 -1.1
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 1.5 -0.0 0.1 0.1 -0.3 0.2 -0.1 -0.8 -0.4 -0.2 -0.5 -0.3 -0.1 -0.4 -0.6 -0.1 -0.3 -0.1 -0.1 0.6 0.2 0.2 0.3 -0.6 -1.2 -0.4 0.0 0.3
Tinnitus: Yes, but not now, but have in the past 4.1 4.3 9.9 2.0 1.9 2.5 2.8 2.4 2.8 2.0 1.8 -1.6 3.2 2.8 2.7 3.0 1.8 1.7 2.9 1.9 1.5 0.4 1.0 2.2 1.4 0.7 -0.9 1.7 1.9 1.6
Qualifications: CSEs or equivalent 1.6 2.2 9.5 -0.9 1.0 0.1 1.1 -0.0 0.4 -0.5 -0.6 -2.2 -0.5 0.2 0.6 0.5 -2.5 -3.1 0.6 -1.8 0.5 -2.6 2.2 0.3 2.2 -0.2 0.7 1.7 2.4 2.0
Serious illness, injury or assault to yourself 0.1 0.2 1.2 0.3 -0.3 -0.0 -0.0 0.1 0.1 -0.3 -0.3 0.4 0.6 0.0 0.4 0.1 0.4 -1.1 0.2 0.2 -0.5 0.3 -0.2 -0.1 -0.4 -1.1 0.2 0.5 -0.3 -0.4
High blood pressure 0.1 0.3 1.6 -0.0 -0.3 -0.3 -0.4 -0.2 -0.3 -0.9 -1.2 0.3 -0.5 -0.4 -0.6 -0.4 -0.4 -0.0 -0.2 -0.5 -0.4 -0.6 0.1 -0.3 -0.5 0.1 1.2 -0.9 -0.6 -0.5
Hayfever, allergic rhinitis or eczema 0.3 0.7 6.1 -0.4 0.5 0.6 0.1 0.5 0.3 0.1 -0.5 0.1 0.1 0.6 -0.1 0.2 0.5 1.9 0.2 0.6 0.8 2.0 -0.5 0.8 -0.3 -0.3 -2.5 -0.5 -1.0 -0.1
Multivitamins +/- minerals 1.6 2.0 6.1 -1.5 -1.2 -1.6 -1.8 -1.6 -1.5 -1.7 -1.6 1.0 -2.5 -1.8 -1.8 -1.7 -1.1 -0.3 -1.9 -1.0 -1.1 0.4 0.1 -1.3 -1.1 -0.5 -0.6 -1.7 -1.6 -1.2
Stomach or abdominal pain in last month 0.5 0.6 5.0 0.3 -0.2 -0.1 0.2 -0.5 0.2 -0.7 -0.8 0.2 -0.0 0.4 -0.1 0.3 0.7 0.4 0.4 0.5 -0.8 1.0 -0.8 -0.2 0.1 -2.2 -2.0 1.0 0.2 0.0
Supplements: Glucosamine 1.5 1.9 4.6 -0.2 -1.3 -1.7 -1.6 -1.4 -1.2 -0.8 -1.5 1.0 -1.7 -2.1 -1.6 -1.4 -1.1 0.2 -1.4 -1.6 -0.7 -0.8 1.4 -1.5 -1.6 0.3 1.5 -1.8 -1.7 -1.7
Diverticular disease/diverticulitis (self-reported) 1.4 1.6 4.4 -0.1 -1.5 -1.5 -1.5 -1.3 -1.1 -0.6 -0.8 1.8 -0.6 -1.4 -0.8 -1.1 0.6 -1.1 -1.5 -0.5 -1.1 -0.0 -0.5 -1.5 -2.1 -1.0 1.5 -1.6 -1.9 -2.1
Medication: Atenolol 1.2 1.5 5.7 -0.9 -1.3 -0.7 -1.4 -0.4 -0.8 -1.5 -1.6 1.7 -0.6 -1.2 -1.4 -0.9 -0.1 -0.4 -1.1 -0.9 -1.0 -0.5 0.1 -0.8 -2.3 -0.4 1.3 -1.6 -2.4 -2.1
Medication: Levothyroxine sodium 0.5 0.9 6.2 1.9 0.3 0.4 -0.1 0.9 0.6 0.4 0.2 0.8 0.6 -0.2 0.3 0.3 1.7 -0.7 0.0 1.1 -0.0 1.1 0.3 0.3 -1.1 0.8 2.5 -1.1 -0.9 -0.9
Sitting height 0.4 2.7 6.8 -2.6 -2.3 -2.1 -1.9 -2.0 -2.2 -2.0 -1.3 1.2 -1.8 -1.7 -1.4 -2.1 -1.5 0.2 -2.1 -1.9 -1.3 -1.7 -1.2 -1.7 -1.0 -0.7 1.2 -0.7 -0.8 -1.2
Chronic bronchitis/emphysema (father) 0.3 0.3 0.9 0.8 -0.4 -0.2 -0.2 0.2 0.0 -0.4 -0.2 0.9 0.1 -0.5 -0.3 -0.0 0.8 -0.7 -0.1 0.2 -1.0 -0.2 -0.5 -0.6 -0.7 -0.9 0.9 -0.8 -0.3 -0.7
High blood pressure (mother) 1.1 1.6 3.1 1.0 1.5 1.6 1.4 1.6 1.2 1.5 1.4 -1.1 1.3 1.6 0.7 1.2 1.0 0.8 1.8 1.4 1.7 0.3 -0.6 1.6 1.4 0.4 0.5 0.4 1.5 1.5
Body mass index (BMI) 0.4 1.6 5.1 1.3 0.9 1.1 1.3 1.2 1.1 0.9 0.3 -1.9 1.2 0.7 1.0 1.0 -0.3 -1.4 1.2 0.3 1.2 -1.4 1.8 1.1 1.8 0.1 2.2 0.5 1.7 1.7
Impedance of leg (left) 1.4 6.7 12.0 -3.1 -2.8 -3.0 -3.3 -3.2 -3.2 -2.6 -1.8 3.5 -1.1 -2.6 -2.7 -3.0 -0.7 0.3 -3.0 -1.7 -2.8 0.8 -3.5 -3.0 -3.0 -2.2 -1.1 -1.5 -2.7 -3.1
Leg predicted mass (left) 0.2 0.8 5.2 0.4 -0.5 -0.3 -0.1 0.0 -0.1 -0.5 -0.4 -0.7 0.2 -0.7 0.4 -0.3 -1.1 -1.9 -0.3 -1.0 0.2 -2.1 1.7 -0.2 0.3 0.2 2.3 -0.6 0.4 0.3
Trunk fat mass 0.3 1.3 3.0 -0.7 -1.5 -1.3 -1.4 -1.1 -1.3 -1.4 -1.2 0.7 0.2 -1.5 -0.8 -1.5 -1.0 -1.2 -1.3 -1.1 -0.6 -1.1 -0.2 -1.1 -0.8 -1.2 1.7 -1.6 -0.9 -0.9
Waist circumference 0.4 1.6 6.8 -0.1 -1.9 -1.2 -1.3 -1.0 -1.1 -1.1 -1.1 1.1 0.1 -1.5 -1.0 -1.2 -0.6 -1.6 -1.1 -1.0 -1.3 -1.7 0.1 -1.3 -1.3 -1.1 2.6 -1.1 -1.1 -1.3
Number of incorrect matches in round 0.2 0.3 2.8 -0.4 0.2 -0.2 -0.1 -0.1 0.1 -0.1 0.1 -0.0 -0.3 -0.2 0.5 0.0 -0.2 -0.9 -0.4 -0.3 0.2 1.1 0.8 -0.1 -0.4 -0.5 -1.7 0.3 -0.4 -0.4
Past tobacco smoking 1.2 2.1 9.2 -0.7 1.0 1.0 1.9 0.7 1.0 1.2 -0.1 -2.0 0.7 1.6 1.1 1.5 -1.1 -0.4 1.6 -1.1 0.4 -3.0 1.2 0.9 2.0 1.0 -0.4 3.0 2.0 1.9
Alcohol usually taken with meals 0.9 1.4 6.9 -0.4 1.3 1.0 1.3 0.8 0.8 0.9 0.7 -1.3 0.9 1.5 1.1 1.1 0.3 2.6 1.3 0.5 1.3 0.3 -0.3 1.2 1.5 -0.3 -1.6 1.4 1.4 1.5
Nervous feelings 1.0 1.8 3.9 -1.6 -1.2 -1.4 -1.2 -1.7 -1.3 -0.9 -2.0 1.7 -1.1 -0.8 -1.8 -1.0 -0.1 -0.3 -1.0 -1.3 -1.4 -0.4 -1.5 -1.6 -1.6 -1.5 -1.7 -0.5 -1.8 -1.7
Frequency of tenseness / restlessness in last 2 weeks 0.7 1.2 5.4 -0.5 -1.0 -0.7 -0.8 -0.9 -0.7 -0.9 -1.2 1.5 -0.8 -0.6 -1.1 -0.5 -0.1 -0.1 -0.8 -0.8 -1.7 0.4 -1.2 -1.0 -1.5 -1.4 -2.3 0.3 -1.6 -1.5
Hearing difficulty/problems with background noise 2.7 4.3 9.1 -0.6 -2.0 -2.1 -2.5 -1.9 -2.0 -1.8 -2.0 3.0 -1.5 -2.4 -2.4 -2.1 0.1 -1.8 -2.3 -1.1 -2.5 0.4 -1.7 -2.4 -2.9 -2.4 -0.1 -1.2 -3.0 -3.0
Hair/balding pattern: Pattern 2 0.4 0.5 2.1 0.4 -0.4 0.0 -0.1 0.0 0.4 -0.1 -0.2 0.9 0.6 0.3 0.5 0.4 1.4 0.0 0.2 0.9 -0.4 1.0 0.2 0.1 -1.4 -0.9 -1.0 -0.0 -1.4 -1.2
Had menopause 0.8 1.0 3.5 -0.1 -0.5 -0.2 -0.7 -0.3 -0.4 -0.3 -0.1 1.7 0.5 -0.2 -1.0 -0.5 1.6 1.4 -0.5 1.1 -1.1 1.6 -1.9 -0.6 -1.3 -0.4 1.4 -1.5 -1.4 -1.2
Had other major operations 0.4 0.5 2.3 -0.4 0.6 0.6 0.5 0.5 0.2 0.1 0.0 -0.7 0.3 0.6 0.3 0.3 -1.2 0.2 0.6 -0.4 0.1 -0.6 -0.0 0.4 0.9 -0.5 -1.5 1.5 1.0 1.0
Forced vital capacity (FVC) 0.4 1.6 3.7 0.5 1.4 1.3 1.2 1.4 1.2 0.8 0.5 -1.9 0.9 1.0 1.2 0.9 -0.4 1.8 1.0 0.6 1.6 0.0 1.3 1.7 1.8 1.7 0.9 0.8 1.7 1.9
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.1 4.2 -0.7 -0.7 -0.9 -1.5 -0.8 -1.2 -1.0 -0.7 1.1 -0.7 -1.1 -1.2 -1.5 -0.3 -0.6 -1.5 -0.2 -0.9 1.0 -1.2 -0.8 -0.8 -2.0 -0.9 -1.5 -1.0 -0.8
Ever unenthusiastic/disinterested for a whole week 0.6 0.8 3.5 -1.4 -1.0 -0.8 -0.8 -0.9 -1.1 -1.1 -0.8 0.6 0.3 -0.7 -0.9 -1.0 -1.1 0.1 -0.7 -1.2 -0.5 -0.7 -0.9 -0.8 -0.2 -1.9 0.0 -0.7 0.1 -0.3
Qualifications: None of the above 0.7 1.5 7.8 -1.6 -1.3 -1.2 -1.1 -1.1 -1.2 -1.2 -0.9 1.6 -0.4 -0.9 -1.5 -1.0 0.1 -1.6 -1.2 -0.4 -1.4 -0.2 -1.1 -1.5 -1.4 -2.8 -0.3 -0.9 -0.9 -1.4
Financial difficulties in last 2 years 0.3 0.4 3.6 -0.0 0.7 0.5 0.5 0.5 0.4 0.5 0.0 -0.9 0.6 0.3 0.6 0.3 -0.3 -1.9 0.4 0.1 0.4 -0.5 0.8 0.6 1.0 0.1 -0.2 0.4 0.9 0.9
Mouth/teeth dental problems 0.2 0.3 3.2 0.1 0.5 0.1 0.2 0.2 0.0 0.4 -0.2 0.1 -0.7 0.1 0.0 0.2 0.1 1.0 0.2 -0.4 -1.0 -1.0 -0.4 -0.1 0.1 0.2 0.4 1.8 0.4 0.1
Heart attack 0.9 1.1 3.5 1.2 0.6 1.5 1.1 1.8 1.3 0.8 0.6 0.1 1.7 1.4 1.1 1.4 1.9 0.5 1.2 1.4 0.5 0.8 -0.6 1.2 -0.1 0.4 0.6 0.8 -0.2 0.1
Allergy 0.4 0.9 2.4 1.2 0.5 0.7 1.0 0.7 0.8 0.9 1.6 -0.9 1.0 0.7 1.2 0.8 0.1 -0.7 0.8 0.6 0.2 -0.9 0.3 0.5 1.1 1.2 1.3 1.3 1.6 1.1
Pain all over the body in last month 0.9 1.0 4.6 0.8 0.5 1.1 0.8 1.5 1.3 0.9 -0.0 -0.7 0.4 0.6 1.4 1.1 0.5 -0.1 1.1 0.8 1.4 1.3 2.1 1.5 -0.3 0.1 -1.1 0.4 -0.7 -0.0
Diabetes (self-reported) 1.0 1.5 3.4 -1.1 -1.9 -1.6 -1.5 -1.7 -1.4 -1.0 -0.7 1.2 -1.3 -1.4 -1.1 -1.4 -0.2 -0.5 -1.4 -0.9 -0.7 -0.0 -0.3 -1.2 -1.5 -0.6 -1.4 -0.5 -1.8 -1.6
Hayfever/allergic rhinitis (self-reported) 0.1 0.1 0.7 -0.9 -0.2 -0.2 -0.3 -0.0 -0.4 0.0 -0.3 0.1 -0.2 -0.3 -0.1 -0.4 -0.5 0.5 -0.2 -0.4 0.1 -0.1 -0.0 -0.1 -0.0 0.4 -0.2 -0.7 -0.2 -0.0
Medication: Ramipril 0.5 0.6 2.7 0.9 -0.2 -0.4 -0.9 -0.3 -0.3 -0.7 -0.5 1.0 -0.2 -0.6 -0.8 -0.6 0.6 -0.4 -0.6 0.6 -0.4 1.3 -0.7 -0.5 -0.9 -0.7 0.8 -1.6 -1.2 -0.9
Medication: Simvastatin 0.6 0.8 2.7 -0.5 -1.3 -0.9 -1.0 -0.6 -0.7 -0.9 -1.0 1.2 -0.0 -1.0 -0.4 -0.7 0.6 0.5 -0.7 -0.2 -0.8 0.7 0.2 -0.6 -1.7 -1.3 -0.7 -0.9 -1.4 -1.6
Fluid intelligence score 1.0 2.2 4.2 1.8 1.6 1.6 1.6 1.7 1.8 1.7 1.5 -1.1 1.9 1.5 2.0 1.6 1.4 0.8 1.7 1.8 1.3 0.6 1.1 1.6 0.9 1.9 1.1 0.5 0.8 1.1
Illnesses of siblings 0.2 0.3 2.5 0.3 0.4 0.1 0.2 -0.2 -0.0 0.1 0.1 -0.2 0.2 0.4 0.1 0.0 0.7 1.0 0.3 0.7 -0.1 1.6 -1.1 0.1 0.6 0.0 -0.9 0.6 0.8 0.5
Neuroticism score 1.5 3.2 5.9 -2.0 -1.7 -1.9 -2.2 -2.1 -2.0 -1.8 -2.1 2.2 -0.9 -1.8 -2.1 -2.0 0.1 -1.5 -1.7 -1.1 -1.9 0.2 -1.4 -1.8 -2.3 -1.8 -0.1 -1.6 -2.4 -2.3
Weight 0.3 1.3 5.9 -0.4 -1.3 -1.1 -0.9 -0.8 -1.0 -1.1 -1.0 0.1 0.0 -1.4 -0.5 -1.1 -1.5 -1.7 -1.0 -1.5 -0.5 -2.2 0.8 -1.0 -0.2 -0.6 2.4 -1.0 -0.1 -0.3
Impedance of arm (right) 0.2 0.7 7.8 -1.4 -0.4 -0.1 -0.4 -0.3 -0.3 -0.2 0.3 0.4 0.6 0.1 0.5 -0.2 -0.3 2.2 -0.3 -0.1 0.4 1.5 -0.8 0.1 -0.4 -0.2 -2.8 -0.1 -0.6 -0.4
Arm fat percentage (right) 0.2 1.0 2.2 0.9 0.6 1.0 1.0 1.1 1.0 0.8 0.1 -1.5 1.5 0.8 1.2 0.9 -0.1 -0.6 1.1 0.4 1.1 -0.7 1.4 1.2 1.2 -0.1 1.3 0.3 1.0 1.2
Trunk fat-free mass 0.6 3.2 9.5 -0.8 -2.3 -2.1 -1.7 -1.7 -1.7 -1.9 -1.8 1.3 -1.2 -2.3 -1.4 -1.7 -1.5 -2.0 -1.8 -2.4 -2.0 -3.1 0.4 -2.2 -1.5 -0.8 2.3 -1.3 -0.9 -1.6
Hip circumference 0.2 0.8 3.7 -0.5 -1.0 -0.8 -0.7 -0.7 -0.8 -0.8 -0.6 0.2 0.4 -1.0 -0.3 -0.9 -1.2 -1.7 -0.7 -1.1 -0.5 -1.7 0.2 -0.8 -0.2 -1.2 1.9 -0.5 -0.0 -0.2
Time employed in main current job 0.6 0.7 3.3 0.8 0.1 0.6 0.4 0.5 0.8 1.0 1.0 0.3 1.2 0.8 0.8 0.7 1.8 1.0 0.4 1.5 0.3 1.1 -0.5 0.6 -0.4 1.3 0.5 0.1 -0.6 -0.3
Alcohol intake versus 10 years previously 0.3 0.4 1.8 -0.5 -0.6 -0.4 -0.5 -0.5 -0.5 -1.1 -1.3 0.1 -0.8 -0.6 -1.0 -0.6 -0.8 -0.7 -0.3 -0.7 -0.8 -0.8 0.1 -0.5 0.1 -0.6 0.5 -1.0 0.1 0.0
Father’s age at death 1.1 1.4 3.2 1.0 1.0 1.6 1.3 1.4 1.1 1.2 1.2 -0.3 1.0 1.7 0.8 1.3 1.8 1.8 1.3 1.7 0.6 0.5 -1.3 1.3 0.6 1.6 0.8 1.0 0.5 0.7
Worrier / anxious feelings 1.0 2.0 5.3 0.5 1.2 1.8 2.1 1.5 1.8 1.2 0.3 -1.0 1.4 2.2 1.4 2.3 0.7 1.9 2.3 0.6 0.4 -1.2 0.5 1.4 0.8 1.0 -0.6 2.1 0.9 0.9
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 1.1 0.5 0.3 0.8 1.0 0.7 0.8 0.5 0.3 -0.4 1.0 0.9 0.8 1.1 1.0 -1.0 0.9 0.8 0.3 0.2 -0.0 0.6 0.4 -0.4 -0.7 0.7 0.4 0.4
Falls in the last year 0.4 0.6 4.6 1.0 0.7 0.6 0.3 0.6 0.6 -0.1 0.6 -0.1 0.6 0.4 0.2 0.4 0.3 -0.3 0.3 1.2 0.6 2.1 -0.2 0.5 0.2 -1.8 -1.3 -0.5 0.2 0.3
Hair/balding pattern: Pattern 3 0.3 0.4 2.5 0.3 0.1 -0.3 0.2 -0.3 0.1 -0.2 -0.1 -1.0 -0.5 -0.4 0.1 0.0 -1.2 0.8 -0.3 -0.9 0.4 -0.7 1.1 -0.2 0.9 1.6 0.4 0.0 0.7 0.7
Number of live births 0.2 0.3 2.1 0.9 0.6 0.4 0.2 0.4 0.2 0.3 0.0 0.4 0.1 0.3 -0.4 0.3 1.1 1.5 0.4 0.8 0.2 0.8 -0.8 0.2 -0.3 -0.3 -0.6 0.3 -0.2 -0.2
Forced expiratory volume in 1-second (FEV1) 1.2 3.9 9.2 1.0 2.3 2.2 2.1 2.2 2.0 1.3 1.1 -3.0 1.4 1.8 2.1 1.8 -0.6 1.5 1.9 0.9 2.5 -0.3 2.1 2.5 2.9 2.2 0.7 1.6 2.9 3.0
Pulse rate 0.3 0.5 2.6 0.1 -0.9 -0.8 -0.3 -0.8 -0.5 -0.5 -0.7 0.4 -0.6 -0.4 -0.3 -0.3 -0.6 -1.2 -0.3 -0.9 -1.0 -1.6 -0.6 -0.9 -0.3 -0.7 1.0 0.1 0.2 -0.4
Happiness 0.3 0.3 1.3 -0.1 -0.6 -0.6 -0.3 -0.8 -0.5 -0.9 -0.6 0.3 0.6 -0.4 -0.7 -0.3 -0.5 0.1 0.1 -0.9 -0.8 -1.1 -0.1 -0.7 -0.3 -0.5 -0.3 0.4 -0.1 -0.4
Noisy workplace 0.5 0.7 1.9 -1.3 -0.6 -0.8 -0.7 -0.7 -0.8 -0.7 -1.2 -0.1 -0.9 -0.8 -0.9 -0.8 -1.4 -1.0 -0.8 -1.3 -0.1 -1.3 0.6 -0.5 -0.2 -0.4 -0.2 -0.7 -0.4 -0.2
Qualifications: A levels/AS levels or equivalent 0.4 0.8 1.8 1.0 0.8 1.1 1.2 1.1 1.3 0.7 0.7 -0.9 0.5 1.1 1.0 1.3 0.5 0.4 1.3 0.7 0.7 -0.1 0.9 1.0 0.6 1.2 0.2 1.1 0.3 0.7
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.5 2.4 0.9 -0.3 0.6 0.0 1.0 0.7 -0.1 -0.6 0.4 1.0 -0.1 0.6 0.4 0.4 -0.7 0.1 0.2 -0.3 0.7 1.0 0.5 -1.0 -0.3 -1.3 -0.1 -1.6 -0.8
Mouth/teeth dental problems: Dentures 0.5 0.9 3.8 -0.4 -1.2 -1.0 -0.9 -1.0 -0.6 -1.2 -0.8 1.0 -0.9 -0.8 -0.8 -0.7 -0.1 -0.2 -0.7 -0.2 -0.4 0.9 0.3 -0.9 -1.3 -1.0 -0.9 -1.9 -1.4 -1.3
Asthma 0.5 0.9 2.2 -0.5 -0.9 -1.1 -0.9 -0.8 -0.8 -0.8 -1.4 1.2 -1.4 -1.2 -1.2 -0.6 0.4 0.3 -0.6 -1.0 -1.1 -0.7 0.5 -1.1 -1.5 -0.3 0.3 -0.8 -1.1 -1.4
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.3 4.9 -0.3 -0.2 0.2 0.1 -0.0 0.1 0.1 1.1 -0.2 0.5 0.3 0.1 0.1 0.2 2.2 0.0 0.6 0.9 0.7 -0.3 0.4 0.0 0.2 -0.1 -1.0 -0.1 0.1
Medication: Cholesterol lowering 1.3 2.0 4.8 -1.2 -2.2 -1.3 -1.4 -1.3 -1.3 -1.3 -0.8 2.2 0.0 -0.8 -0.6 -1.1 1.3 1.2 -1.0 -0.1 -1.7 0.6 -2.0 -1.3 -2.1 -1.3 -1.3 -0.6 -2.1 -2.1
Depression (self-reported) 1.3 1.6 5.3 -0.7 -1.4 -1.4 -0.8 -1.4 -0.9 -1.2 -2.0 0.4 -1.1 -1.4 -0.7 -0.8 -1.6 -2.3 -1.3 -2.2 -1.2 -1.2 1.2 -1.4 -0.7 -0.3 -0.9 -0.9 -0.7 -0.8
Medication: Lansoprazole 1.8 2.1 5.5 -1.1 -1.9 -1.3 -1.3 -1.1 -1.4 -1.3 -1.5 2.0 0.1 -1.0 -1.5 -1.1 -0.2 -0.2 -1.2 -1.0 -1.6 -1.5 -1.5 -1.6 -1.8 -2.3 1.9 -0.9 -1.7 -1.8
Prospective memory result 2.7 3.3 7.1 -0.9 -2.0 -1.8 -1.6 -1.9 -1.7 -1.8 -2.1 2.5 -2.6 -1.4 -2.5 -1.2 0.1 1.6 -1.1 -1.4 -2.7 -0.7 -1.6 -2.2 -2.4 -2.1 -1.0 -0.5 -1.9 -2.5
Lung cancer (father) 1.1 1.3 3.9 -0.0 -1.1 -0.9 -0.9 -0.9 -0.7 -0.8 -0.5 2.0 0.2 -0.6 -1.1 -0.5 1.8 0.2 -0.8 0.4 -1.6 0.7 -1.6 -1.2 -1.9 -1.1 -1.0 -0.6 -1.8 -1.9
Illnesses of mother 0.2 0.3 1.0 0.7 0.0 -0.5 -0.4 -0.6 -0.1 -0.2 -0.6 0.5 -0.2 -0.5 0.1 -0.3 -0.2 -0.4 -0.6 -0.2 -0.7 -0.2 0.1 -0.6 -0.5 1.0 1.0 -0.8 -0.4 -0.6
Forced expiratory volume in 1-second (FEV1), Best measure 1.1 3.6 8.0 1.2 2.0 2.3 2.1 2.1 1.9 1.1 1.1 -2.7 1.0 2.1 1.9 1.8 -0.1 1.8 2.0 1.3 2.2 0.1 1.1 2.5 2.7 2.0 0.6 1.8 2.8 2.8
Pulse wave Arterial Stiffness index 1.0 1.1 3.1 -0.1 -1.6 -1.2 -0.9 -1.0 -0.7 -1.3 -1.1 1.4 -0.1 -1.0 -0.2 -0.6 0.5 -1.4 -0.7 -0.5 -1.8 0.1 -0.2 -1.2 -1.6 -1.3 -0.3 -0.1 -1.6 -1.7
Impedance of arm (left) 0.2 0.9 4.0 -1.2 -0.5 -0.3 -1.0 -0.6 -0.7 -0.5 0.2 1.1 0.5 -0.2 -0.1 -0.8 0.1 1.7 -0.7 0.2 0.0 2.0 -1.7 -0.2 -1.0 -0.4 -2.0 -0.9 -1.2 -0.9
Arm fat mass (right) 0.1 0.5 4.5 0.5 -0.1 0.1 0.1 0.2 0.1 0.0 -0.4 -0.7 0.9 -0.3 0.3 -0.1 -0.6 -1.2 0.1 -0.3 0.3 -1.3 0.9 0.2 0.6 -0.4 2.1 -0.3 0.6 0.6
Trunk predicted mass 0.5 3.0 8.8 -0.8 -2.3 -2.0 -1.7 -1.7 -1.7 -1.8 -1.7 1.2 -1.2 -2.3 -1.4 -1.7 -1.5 -1.9 -1.8 -2.3 -2.0 -3.0 0.4 -2.2 -1.4 -0.8 2.2 -1.3 -0.9 -1.6
Standing height 1.6 15.4 26.3 -3.9 -5.1 -5.0 -5.0 -4.7 -4.8 -4.5 -2.9 4.1 -2.7 -5.0 -3.4 -4.8 -3.0 -0.7 -5.0 -4.3 -3.7 -2.3 -1.9 -4.8 -4.2 -1.7 0.8 -3.6 -3.8 -4.4
Length of working week for main job 2.9 3.2 8.5 2.3 1.9 1.9 1.7 1.9 1.9 2.3 2.5 -0.9 2.9 1.9 1.8 1.8 2.2 1.5 1.7 2.8 1.3 1.3 -0.1 1.8 1.0 1.4 1.4 0.8 0.9 1.2
Exposure to tobacco smoke at home 0.9 1.0 4.2 -2.0 -1.4 -0.9 -0.9 -0.8 -0.9 -1.7 -1.8 0.7 -0.4 -0.8 -0.8 -0.8 0.3 -1.2 -0.9 -0.3 -1.7 0.1 0.0 -0.7 -0.8 -0.9 -0.7 0.4 -0.9 -0.8
Breastfed as a baby 0.7 0.8 5.7 0.2 0.6 0.6 0.8 0.9 0.8 0.9 0.6 -0.7 1.4 0.4 0.9 0.8 0.2 0.2 0.6 0.2 0.3 -1.2 1.4 0.5 0.6 2.4 1.8 0.3 0.8 0.6
Tense / ‘highly strung’ 0.8 1.4 3.5 -0.8 -1.1 -1.2 -1.4 -1.2 -1.2 -0.5 -0.9 1.4 -1.7 -1.1 -1.5 -1.2 -0.5 -0.9 -1.2 -0.9 -0.9 0.1 -0.6 -1.2 -1.6 -0.8 -0.9 -1.4 -1.9 -1.5
Seen doctor (GP) for nerves, anxiety, tension or depression 0.7 1.0 3.6 -0.7 -1.0 -0.5 -0.9 -0.6 -0.7 -1.2 -1.7 1.2 0.3 -0.5 -0.6 -0.7 0.0 -0.7 -0.6 -0.3 -0.9 1.1 -0.7 -0.5 -1.2 -1.9 -1.8 -0.7 -1.6 -1.2
Hair/balding pattern: Pattern 4 1.1 2.7 6.9 -2.3 -1.4 -1.9 -2.4 -1.6 -2.4 -1.5 -1.1 1.1 -1.7 -2.3 -2.3 -2.6 -1.3 -1.4 -2.5 -1.1 -0.6 0.3 -1.0 -1.3 -0.8 -0.7 0.9 -2.2 -0.9 -1.0
Birth weight of first child 3.1 5.6 17.3 3.2 2.4 2.7 2.7 2.7 2.8 2.6 2.8 -2.3 1.7 2.4 2.9 2.8 1.3 0.0 2.6 2.1 2.5 0.4 2.0 2.5 1.9 4.2 1.1 1.2 1.7 2.1
Peak expiratory flow (PEF) 3.2 7.4 13.6 2.1 3.4 3.2 3.2 3.3 3.3 2.2 1.5 -3.7 2.5 2.7 3.5 3.0 0.4 1.5 3.0 1.7 3.5 0.6 3.3 3.6 3.0 2.7 -0.4 1.8 2.6 3.3
Pulse wave reflection index 2.0 2.4 7.1 1.6 1.7 1.7 1.5 1.6 1.7 1.6 1.3 -1.0 2.7 1.7 1.8 1.7 2.2 0.8 1.8 2.2 1.1 2.0 0.4 1.9 0.8 1.0 -0.5 1.5 0.3 1.0
Ever highly irritable/argumentative for 2 days 1.6 1.9 4.4 -1.5 -1.5 -1.6 -1.2 -1.5 -1.6 -2.1 -1.9 0.6 -1.3 -1.6 -1.5 -1.5 -1.7 -1.5 -1.4 -2.1 -1.4 -1.7 -0.3 -1.6 -0.3 -1.2 0.9 -0.5 0.1 -0.5
Loud music exposure frequency 1.3 1.4 2.7 1.3 1.4 1.3 1.4 1.3 1.4 0.8 1.1 -1.2 1.5 1.3 1.6 1.4 1.0 0.5 1.4 1.2 1.1 0.2 0.8 1.3 1.0 1.0 0.8 1.0 0.8 1.1
Qualifications: O levels/GCSEs or equivalent 1.5 2.4 8.0 1.7 1.3 1.6 1.5 1.5 1.7 1.4 1.9 -1.2 1.8 1.6 2.0 1.5 1.0 -0.2 1.7 1.7 1.2 0.0 0.7 1.6 1.1 2.6 2.8 1.2 0.8 1.2
Mouth/teeth dental problems: Bleeding gums 0.6 0.7 2.5 -0.3 0.5 -0.1 0.2 -0.1 -0.0 0.3 0.7 -1.4 0.1 -0.2 0.3 -0.2 -1.6 -1.0 -0.3 -0.7 1.6 -0.9 1.1 0.3 1.3 1.2 1.3 -0.6 1.0 1.2
Blood clot in the leg (DVT) 1.1 1.4 4.0 0.8 1.4 1.0 1.0 1.1 1.1 1.1 0.9 -2.0 0.5 0.7 1.1 0.7 -1.3 -0.7 0.8 0.0 1.9 -0.2 1.8 1.4 1.7 1.2 0.8 0.9 1.7 1.7
Medication: Paracetamol 0.1 0.2 0.8 0.5 0.1 0.6 0.5 0.7 0.3 -0.2 -0.5 -0.3 0.4 0.4 -0.0 0.4 -0.7 -0.2 0.3 -0.5 0.2 -0.4 -0.1 0.3 0.4 -0.9 -0.5 0.4 0.5 0.4
Headache pain in last month 0.5 0.9 2.7 -1.3 -1.2 -1.3 -0.5 -1.4 -1.1 -0.8 -0.8 -0.3 -0.9 -1.1 -1.0 -0.9 -1.3 -1.6 -0.8 -1.6 -0.7 -1.1 0.4 -1.1 0.3 -0.6 -0.4 0.5 0.3 0.1
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 1.5 0.5 1.1 0.8 0.7 0.7 0.7 0.8 0.6 -1.0 0.4 0.6 0.6 0.5 -0.6 0.0 0.5 0.3 0.7 -0.2 1.0 0.7 0.9 0.9 1.2 0.2 0.8 1.0
Glaucoma (self-reported) 1.3 1.6 3.6 -0.7 -1.3 -1.4 -1.6 -1.3 -1.3 -1.1 -1.2 1.2 -0.8 -1.7 -1.5 -1.5 -0.6 -1.9 -1.5 -1.0 -1.1 -0.0 -0.1 -1.2 -1.4 -1.1 -0.0 -1.7 -1.4 -1.5
Gout (self-reported) 0.3 0.5 2.7 -0.9 -1.2 -0.5 -0.5 -0.5 -0.2 -0.1 -0.2 0.5 0.4 -0.3 0.5 -0.2 0.4 1.7 -0.5 0.1 0.0 0.4 0.5 -0.2 -1.0 0.5 -1.2 0.0 -1.2 -0.9
Hypothyroidism/myxoedema (self-reported) 0.7 1.3 8.7 2.3 0.4 0.6 -0.2 1.1 0.8 0.3 0.3 0.8 1.0 -0.2 0.5 0.3 2.0 -1.1 0.0 1.6 0.1 1.7 0.4 0.5 -1.2 0.9 3.0 -1.5 -1.1 -0.9
Medication: Amlodipine 0.5 0.7 2.2 -1.1 -0.9 -1.1 -0.8 -1.2 -0.8 -0.6 -0.5 0.5 -1.2 -0.8 -0.9 -0.8 -0.4 -0.8 -0.9 -0.7 -1.0 0.1 0.1 -0.8 -0.7 -0.9 -1.5 0.3 -0.9 -0.7
Medication: Ventolin 100micrograms inhaler 0.6 0.8 4.4 1.1 -0.5 -0.1 -0.7 0.3 0.1 -0.2 0.0 1.6 -0.2 -0.6 -0.6 -0.1 1.0 -0.3 -0.3 0.4 -0.3 0.4 0.0 -0.4 -2.1 0.1 1.1 -1.8 -1.8 -1.8
Birth weight 0.6 1.4 5.0 0.7 1.4 1.4 1.1 1.3 1.2 1.6 1.4 -1.0 1.0 1.3 1.1 1.1 1.0 0.2 1.1 1.4 1.8 0.5 0.5 1.5 0.8 2.2 0.6 0.0 0.6 1.0
Chronic bronchitis/emphysema (mother) 0.6 0.7 3.5 1.9 0.5 0.8 0.6 0.9 1.0 1.1 0.6 0.2 0.2 0.6 0.4 0.9 1.5 1.6 0.9 1.0 -0.2 0.7 -0.1 0.5 -0.4 1.2 0.5 0.8 -0.7 -0.2
High blood pressure (siblings) 0.4 0.6 2.1 1.1 0.7 0.8 0.6 1.2 1.1 0.6 0.6 -0.5 -0.2 0.5 0.7 0.9 0.2 -1.2 0.6 0.4 1.4 -0.1 1.3 0.9 -0.0 -0.1 1.1 -1.0 -0.4 0.1
Forced vital capacity (FVC), Best measure 0.6 2.1 5.0 0.9 1.4 1.8 1.6 1.7 1.6 0.7 0.8 -1.8 0.8 1.7 1.5 1.5 0.4 2.2 1.6 1.3 1.6 0.4 0.6 2.0 1.7 1.5 0.5 1.2 1.8 1.9
Body fat percentage 0.2 0.7 2.2 -0.4 -1.1 -0.8 -1.0 -0.7 -0.8 -1.0 -1.1 0.4 0.5 -1.0 -0.6 -1.0 -0.6 -1.1 -0.8 -0.6 -0.3 -0.6 0.0 -0.6 -0.5 -1.2 1.5 -1.1 -0.8 -0.6
Leg fat percentage (right) 0.3 1.1 3.3 -0.7 -1.3 -1.1 -0.9 -1.0 -1.1 -1.3 -1.6 0.3 0.2 -1.3 -0.9 -1.1 -1.0 -1.8 -1.0 -1.2 -0.8 -1.5 0.3 -1.0 -0.3 -1.2 1.7 -0.6 -0.3 -0.4
Arm fat-free mass (right) 0.6 3.3 10.4 -0.7 -2.2 -2.0 -1.9 -1.7 -1.8 -2.0 -1.8 1.5 -1.0 -2.3 -1.6 -1.9 -1.1 -2.3 -1.9 -1.8 -2.0 -2.6 -0.1 -2.1 -1.6 -0.7 3.2 -1.5 -1.2 -1.7
Exposure to tobacco smoke outside home 0.2 0.3 1.1 -0.7 0.3 -0.0 0.1 0.1 -0.1 -0.1 -0.3 -1.1 0.0 -0.0 0.4 -0.2 -0.3 -0.6 0.1 0.0 0.5 -0.2 0.6 0.6 0.9 0.7 0.8 0.4 0.8 0.9
Comparative body size at age 10 2.1 5.7 9.7 2.8 2.5 3.1 2.8 3.1 3.0 2.6 2.5 -2.1 2.8 2.9 2.5 2.8 1.2 2.3 3.0 2.6 2.4 1.1 0.9 2.7 2.2 1.4 -0.6 1.6 2.0 2.4
Number of full brothers 3.6 4.5 9.6 -1.9 -2.6 -2.5 -2.3 -2.5 -2.2 -2.3 -2.2 2.6 -1.8 -2.2 -2.6 -2.0 -0.1 0.0 -2.3 -1.5 -2.5 0.1 -1.7 -2.6 -2.4 -3.1 -1.3 -1.2 -1.8 -2.6
Worry too long after embarrassment 2.2 3.7 7.6 -2.3 -2.0 -2.2 -2.3 -2.5 -2.5 -1.6 -1.9 2.2 -1.0 -1.9 -2.8 -2.3 -0.6 -0.3 -2.2 -1.5 -2.3 -0.7 -2.5 -2.4 -1.5 -1.4 0.7 -1.5 -1.4 -1.8
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.3 2.3 -0.4 -0.5 -0.3 -0.2 -0.2 -0.0 -0.5 -0.9 0.2 0.4 -0.4 -0.2 -0.1 -0.5 -1.3 -0.4 -0.7 -0.5 0.3 0.7 -0.4 -0.4 -0.5 -1.5 0.3 -0.4 -0.3
Wheeze or whistling in the chest in last year 0.6 1.1 4.0 0.1 -1.0 -0.8 -0.8 -0.7 -0.5 -0.5 -0.7 2.0 0.3 -0.7 -0.7 -0.4 1.5 0.2 -0.5 0.0 -1.8 0.4 -1.0 -1.3 -1.9 -1.0 -0.8 -0.4 -1.5 -1.9
Number of children fathered 0.1 0.1 0.7 0.9 0.6 0.0 -0.3 0.1 0.1 -0.4 -0.5 -0.2 0.4 -0.4 0.2 -0.3 -0.8 -0.6 -0.1 -0.1 -0.2 0.5 0.4 -0.0 0.3 -0.1 0.4 -0.2 0.1 0.2
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 1.4 0.3 0.5 0.5 0.3 0.2 0.3 0.5 0.7 -0.2 0.2 0.4 0.1 0.3 0.3 1.2 0.3 0.6 -0.2 0.2 -0.3 0.3 0.5 1.2 0.3 0.8 0.2 0.4
Age at first live birth 0.3 0.5 2.3 -0.6 -0.3 -0.4 -0.3 -0.6 -0.6 -0.5 -1.2 -0.4 -1.0 -0.5 -0.9 -0.5 -1.3 0.2 -0.3 -1.2 -0.0 -0.8 0.3 -0.1 0.4 1.5 -0.5 0.1 0.6 0.3
Pulse wave peak to peak time 0.8 1.0 2.7 -0.0 1.4 1.0 0.8 0.9 0.6 1.0 0.9 -1.4 0.0 0.8 0.2 0.5 -0.9 1.2 0.6 0.1 1.6 -0.6 0.3 1.0 1.6 1.3 0.5 0.0 1.6 1.6
Health satisfaction 2.6 3.4 7.4 2.6 1.5 2.1 2.6 2.5 2.6 1.1 0.5 -1.8 2.0 1.9 2.7 2.7 0.6 0.4 2.6 0.7 1.1 -1.2 2.5 1.8 1.2 1.6 0.3 2.0 1.3 1.4
Shortness of breath walking on level ground 0.3 0.3 1.5 1.1 0.5 0.3 0.4 0.6 0.6 0.5 -0.3 -0.2 0.0 0.0 0.3 0.6 -0.4 -1.2 0.3 -0.6 0.3 -0.7 1.1 0.1 -0.3 -1.2 -0.2 0.1 0.0 -0.2
Qualifications: College or University degree 0.1 0.2 0.9 0.9 0.1 0.3 0.1 0.5 0.4 0.1 -0.4 -0.3 -0.9 -0.2 -0.1 0.2 -0.1 0.9 0.2 -0.2 0.4 0.4 1.0 0.3 -0.1 0.8 -0.8 0.0 -0.4 -0.0
Eye problems/disorders: None of the above 0.2 0.2 0.9 0.1 0.0 0.2 0.0 0.2 -0.0 0.2 0.5 0.2 0.4 0.3 0.7 -0.0 0.5 0.6 -0.0 0.4 0.4 0.6 -0.9 0.1 0.1 0.3 0.9 -0.7 0.2 0.1
Mouth/teeth dental problems: Loose teeth 0.5 0.6 6.7 -0.3 -1.0 -0.1 -0.3 -0.1 -0.2 0.3 0.6 1.2 0.4 0.2 -0.3 0.1 1.1 2.6 0.1 0.7 -0.5 0.3 -1.0 -0.3 -1.2 0.1 -0.2 -0.1 -1.0 -1.1
Emphysema/chronic bronchitis 9.3 10.5 20.8 -1.6 -4.2 -4.0 -3.8 -3.8 -3.4 -3.4 -3.4 4.0 -2.1 -3.9 -3.3 -3.3 -1.0 -2.2 -3.7 -3.0 -4.6 -1.0 -1.8 -4.4 -3.9 -1.9 1.0 -1.6 -3.5 -4.1
Medication for pain relief, constipation, heartburn 0.1 0.2 1.7 0.1 0.8 -0.0 0.2 -0.1 0.3 0.2 -0.4 -0.5 -0.3 0.1 0.3 0.2 0.2 0.0 0.2 0.2 -0.4 0.1 0.6 0.1 0.5 1.3 0.0 0.9 0.6 0.4
Neck or shoulder pain in last month 0.6 0.9 3.0 0.2 0.7 0.6 1.2 0.5 0.7 -0.3 0.4 -1.1 1.1 1.0 1.2 0.9 -0.3 -0.6 1.0 0.2 0.2 -0.3 -0.1 0.5 1.6 -1.3 -1.1 1.7 1.7 1.4
Medication: Blood pressure 0.1 0.1 1.3 0.1 -0.0 0.0 0.2 0.1 0.1 -0.2 0.0 -0.5 0.2 -0.1 0.2 0.1 -0.3 -0.3 0.2 -0.3 0.5 -0.0 0.5 0.3 0.3 -0.1 -1.1 0.1 0.3 0.3
Angina (self-reported) 0.5 0.7 3.4 1.1 -0.2 0.8 0.6 1.0 0.8 0.2 -0.3 0.8 0.9 0.8 0.4 1.1 1.8 1.2 0.9 0.8 -0.2 0.2 -0.2 0.3 -1.0 1.1 0.1 -0.9 -1.0 -0.8
Migraine (self-reported) 1.0 1.2 3.9 0.3 0.8 0.9 1.3 0.8 0.9 -0.5 -0.8 -1.9 -0.5 0.8 0.7 0.9 -1.2 0.5 1.1 -0.5 1.1 -0.3 1.4 1.0 2.0 0.2 -1.2 0.3 2.0 1.9
Medication: Ibuprofen 0.2 0.2 4.5 -0.5 -0.4 0.1 0.3 -0.1 0.1 -0.3 0.3 -0.2 0.3 0.4 0.2 0.3 0.2 2.1 0.3 0.2 0.1 -0.2 -0.2 0.2 0.0 -0.1 -0.2 0.2 -0.0 0.1
Medication: Allopurinol 0.4 0.5 2.1 -0.9 -1.5 -0.6 -0.6 -0.6 -0.5 -0.7 -1.0 0.9 0.1 -0.3 -0.1 -0.4 0.2 1.4 -0.4 -0.1 -0.4 -0.2 -0.4 -0.5 -1.1 -0.9 -0.4 -0.3 -1.2 -1.1
Medication: Omeprazole 1.7 2.1 5.6 -0.4 -1.5 -1.6 -1.8 -1.8 -1.5 -0.9 0.1 2.0 -0.5 -1.4 -1.8 -1.7 0.4 -0.6 -1.7 0.1 -1.4 1.5 -2.4 -1.8 -1.3 -2.1 0.1 -1.9 -1.1 -1.5
Medication: Seretide 50 evohaler 0.3 0.4 1.8 1.1 0.4 0.1 0.1 0.3 0.5 0.7 0.5 0.5 0.7 0.2 0.3 0.4 1.0 -1.0 0.4 0.4 0.4 0.2 0.4 0.0 -0.9 -0.5 1.4 -0.5 -0.7 -0.8
Mean time to correctly identify matches 0.4 0.7 7.4 -0.5 0.8 0.7 0.5 0.5 0.5 0.7 0.5 -0.7 -0.1 0.8 0.3 0.5 -0.0 0.6 0.6 0.5 1.6 1.1 0.5 0.9 0.6 -0.9 -2.7 -0.0 -0.2 0.6
Heart disease (mother) 1.1 1.3 3.9 1.5 0.7 1.2 1.2 1.2 1.3 1.7 0.8 0.1 0.8 1.3 0.7 1.5 2.0 1.8 1.2 1.1 0.2 0.6 -0.1 0.8 -0.2 1.6 -1.6 1.6 -0.3 -0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.9 3.5 6.0 1.6 2.4 2.4 2.2 2.4 2.2 2.4 1.8 -1.9 1.5 2.3 2.2 2.2 0.7 0.8 2.3 1.7 2.0 0.3 1.4 2.4 1.5 1.4 -0.0 2.0 1.5 1.8
Whole body fat mass 0.3 1.4 3.6 -0.7 -1.5 -1.2 -1.3 -1.1 -1.2 -1.4 -1.5 0.6 0.0 -1.6 -0.8 -1.4 -1.1 -1.7 -1.2 -1.3 -0.7 -1.4 0.2 -1.1 -0.7 -1.3 1.9 -1.2 -0.7 -0.7
Leg fat mass (right) 0.3 1.3 6.7 -0.3 -1.1 -1.0 -0.7 -0.7 -0.9 -1.2 -1.5 -0.0 0.1 -1.2 -0.6 -1.0 -1.3 -2.2 -0.9 -1.4 -0.6 -2.1 0.6 -0.9 -0.0 -0.9 2.6 -0.5 0.1 -0.1
Arm predicted mass (right) 0.8 4.1 11.0 -0.7 -2.4 -2.3 -2.2 -2.0 -2.1 -2.3 -2.1 1.7 -1.3 -2.6 -1.9 -2.2 -1.1 -2.4 -2.2 -2.0 -2.3 -2.5 -0.3 -2.4 -1.8 -1.0 3.3 -1.7 -1.4 -1.9
Pulse rate, automated reading 0.1 0.2 1.3 0.3 -0.5 -0.1 0.4 -0.4 0.2 -0.1 -0.6 0.2 0.2 0.5 0.3 0.4 0.8 -0.0 0.5 0.2 -0.8 -0.6 -0.7 -0.2 -0.2 -1.2 -0.1 0.8 -0.1 -0.2
Alcohol intake frequency. 0.3 0.6 3.7 0.0 0.4 0.8 0.9 0.8 0.5 0.3 -0.6 -1.0 0.6 0.7 -0.0 0.6 -0.6 -1.9 0.8 -0.2 0.5 -1.0 0.2 0.7 1.3 0.1 -0.1 0.6 1.4 1.2
Comparative height size at age 10 2.0 11.0 19.7 -3.5 -4.4 -4.1 -4.4 -4.0 -4.2 -4.0 -2.8 3.8 -1.6 -4.0 -3.0 -4.3 -1.6 -0.9 -4.3 -2.8 -3.6 -0.6 -2.4 -3.9 -3.7 -0.9 0.2 -2.7 -3.5 -3.9
Number of full sisters 0.2 0.2 1.9 0.2 0.7 0.1 0.2 0.2 0.1 0.9 0.9 0.0 1.4 0.1 0.2 0.1 0.4 -0.6 -0.0 0.3 0.1 0.2 -0.7 -0.0 0.3 0.2 0.1 0.0 0.6 0.2
Suffer from ‘nerves’ 1.6 2.5 6.0 -1.9 -1.8 -1.5 -1.8 -1.7 -1.7 -1.9 -2.0 2.1 -0.5 -1.3 -1.8 -1.5 0.0 0.4 -1.2 -1.0 -1.3 0.7 -1.6 -1.5 -2.1 -1.8 -1.0 -1.2 -2.5 -2.1
Overall health rating 0.4 0.9 3.3 1.0 -0.4 0.4 0.1 0.6 0.7 0.2 0.3 0.9 1.7 0.5 1.0 0.6 1.6 -1.8 0.3 1.3 0.1 1.0 -0.2 0.4 -1.4 -1.4 0.5 -1.0 -1.5 -1.2
Chest pain or discomfort 0.5 0.7 2.0 0.3 -0.3 0.8 1.0 1.2 1.2 0.3 0.1 -0.3 1.1 0.7 1.1 1.3 1.0 0.4 1.0 0.4 -0.1 -0.6 1.4 0.7 -0.3 1.2 -0.3 1.4 -0.8 -0.2
Had major operations 0.9 1.0 3.5 0.4 0.8 1.0 0.6 0.6 0.6 0.1 0.6 0.5 0.8 1.5 0.3 0.8 1.7 1.2 0.7 1.7 0.4 1.9 -1.8 0.8 -0.2 -1.3 -1.9 0.2 -0.3 -0.1
Age at last live birth 0.5 0.7 3.2 -0.1 -0.0 0.1 0.5 0.1 0.2 -0.5 -1.4 -1.0 -0.8 -0.0 -0.4 0.3 -1.1 -1.2 0.2 -1.2 -0.2 -1.8 1.6 0.3 0.6 1.5 0.1 1.4 0.9 0.5
Family relationship satisfaction 0.3 0.3 3.0 -0.6 -0.5 -0.4 -0.0 -0.6 -0.2 -0.2 -0.5 0.3 0.0 0.1 -0.3 -0.0 0.2 1.7 0.5 -0.5 -0.5 -0.5 -0.5 -0.3 -0.4 -0.6 -1.1 0.8 -0.3 -0.4
Leg pain on walking 0.4 0.5 2.3 1.5 0.1 0.8 0.4 1.1 0.8 0.5 0.6 0.1 0.7 0.3 0.6 0.6 0.7 -0.5 0.6 0.8 0.8 0.4 0.8 0.7 -0.6 -0.0 0.7 -1.1 -0.7 -0.4
Qualifications: NVQ or HND or HNC or equivalent 0.6 0.8 3.9 -0.9 -0.5 -0.8 -0.6 -0.9 -0.8 -0.6 -1.0 0.6 -0.5 -0.6 -1.2 -0.7 -0.9 -1.4 -0.7 -1.3 -0.9 -2.0 -0.9 -1.0 -0.2 -0.7 1.0 -0.3 -0.1 -0.4
Commuting to job workplace: Car/motor vehicle 0.3 0.4 2.6 -0.2 -0.1 -0.5 -0.3 -0.6 -0.6 -0.5 0.2 0.0 -0.6 -0.3 -0.4 -0.6 -0.9 -0.7 -0.4 -0.5 -0.4 -0.5 -1.2 -0.6 0.6 -1.6 -0.0 0.2 0.7 0.4
Illness, injury, bereavement, stress in last 2 years 0.3 0.3 3.0 -0.5 0.2 -0.5 -0.3 -0.6 -0.4 -0.5 -0.3 -0.4 -1.7 -0.3 -0.2 -0.5 -0.9 0.3 -0.5 -0.5 0.8 0.0 0.2 -0.1 0.4 -0.8 0.1 -0.5 0.3 0.3
Medication: Aspirin 0.6 0.8 2.9 1.4 0.2 1.0 0.5 1.1 0.8 1.1 1.7 0.4 1.7 0.8 0.9 0.8 1.3 0.2 0.9 1.3 0.8 0.4 -0.2 0.6 -0.4 0.9 1.1 -0.4 -0.8 -0.3
Supplements: Vitamin C 1.0 1.2 5.6 -1.9 -0.8 -0.9 -1.0 -1.0 -1.2 -1.4 -1.2 -0.0 -2.4 -1.1 -1.6 -1.3 -1.5 0.2 -1.2 -1.1 -0.9 -0.2 0.0 -0.7 0.4 -0.0 -1.5 -0.3 0.3 0.2
Knee pain experienced in last month 0.8 1.3 4.9 0.3 -1.1 -1.1 -0.8 -0.9 -0.6 -1.1 -1.5 1.1 -0.7 -1.2 -1.0 -0.7 -0.3 -2.1 -0.9 -0.9 -1.6 -1.1 0.0 -1.4 -1.2 -1.2 2.2 -0.8 -1.0 -1.3
Hypertension (Self-reported) 0.2 0.6 1.8 -0.3 -0.8 -0.7 -0.8 -0.5 -0.6 -1.0 -1.3 0.8 -0.7 -0.8 -1.0 -0.7 -0.2 -0.0 -0.5 -0.5 -0.7 -0.6 -0.1 -0.6 -1.0 -0.3 1.3 -1.1 -1.0 -1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 4.4 -1.2 -0.4 -0.4 -0.0 -0.4 -0.6 -0.3 -0.3 -0.8 -0.5 -0.4 -0.5 -0.5 -1.6 -1.5 -0.5 -1.2 0.3 -2.1 0.3 -0.4 1.3 -0.3 1.7 -0.4 1.2 1.0
Illnesses of father: Heart disease 0.2 0.3 2.0 0.2 -0.3 0.0 -0.0 0.2 0.1 -0.2 -0.6 0.3 -0.4 -0.3 -0.6 0.1 -0.2 1.4 0.2 -0.4 -0.7 -1.1 0.7 -0.2 -0.5 -0.3 0.8 0.3 -0.6 -0.5
Illnesses of siblings: Diabetes 0.4 0.5 1.7 0.3 0.8 0.6 0.2 0.8 0.4 0.7 0.6 -0.7 1.2 0.0 0.5 0.2 -0.3 -0.9 -0.0 0.2 0.9 -0.5 1.1 0.6 0.5 1.3 0.5 -0.9 0.5 0.5
Smoking status: Previous 2.0 3.0 14.4 0.9 -1.0 -1.4 -2.4 -1.2 -1.4 -1.4 -0.5 2.0 -1.9 -2.2 -1.8 -2.1 0.5 -0.3 -2.2 0.5 -0.5 2.5 -1.0 -1.3 -2.1 -0.8 1.4 -3.8 -2.2 -2.0
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.5 1.5 -0.0 -1.0 -0.7 -0.7 -0.8 -0.7 -0.8 0.2 0.9 -0.2 -0.6 -0.0 -0.7 -0.2 -0.9 -0.8 -0.6 -1.1 -0.7 -1.2 -0.9 -0.7 -0.1 1.2 0.1 -0.3 -0.7
Whole body fat-free mass 0.3 1.8 7.6 -0.3 -1.6 -1.4 -1.1 -1.0 -1.1 -1.4 -1.2 0.5 -0.6 -1.7 -0.7 -1.2 -1.4 -2.1 -1.3 -1.8 -1.2 -2.8 1.0 -1.4 -0.8 -0.4 2.5 -1.1 -0.5 -0.9
Leg fat-free mass (right) 0.1 0.7 5.6 0.8 -0.2 -0.0 0.1 0.3 0.2 -0.1 0.1 -0.8 0.4 -0.4 0.6 -0.0 -0.8 -1.6 -0.0 -0.6 0.5 -1.8 1.7 0.1 0.4 0.5 2.4 -0.5 0.4 0.4
Arm fat percentage (left) 0.2 0.7 2.4 1.0 0.5 0.9 0.8 1.0 0.8 0.5 -0.1 -1.1 1.4 0.6 0.9 0.7 0.1 -0.9 0.9 0.6 1.0 -0.5 1.0 1.0 0.9 -0.3 1.6 -0.1 0.6 1.0
Average weekly red wine intake 0.4 0.5 1.9 -1.1 -0.2 -0.7 -1.0 -0.7 -1.0 -0.7 -0.4 0.5 -0.3 -0.9 -0.3 -1.1 -0.8 0.4 -1.0 -0.6 -0.1 0.7 -0.9 -0.5 -0.3 -1.4 -1.3 -0.6 -0.5 -0.3
Handedness (chirality/laterality): Left-handed 0.3 0.3 1.9 -1.4 -0.7 -0.6 -0.2 -0.7 -0.6 -0.1 -0.0 -0.0 -0.5 -0.2 -0.5 -0.3 -0.4 -0.4 -0.2 -0.6 -0.5 -1.0 -0.1 -0.4 0.1 -0.8 -0.5 1.0 0.4 0.0
Mood swings 0.7 1.2 2.6 -1.3 -1.6 -1.4 -1.2 -1.3 -1.3 -1.1 -1.2 1.0 -1.0 -1.5 -1.3 -1.2 -0.2 -1.0 -1.1 -1.3 -1.3 -0.5 0.2 -1.2 -1.1 -0.2 -0.4 -0.4 -1.1 -1.3
Loneliness, isolation 1.7 2.3 5.9 -2.4 -1.8 -1.9 -1.6 -2.1 -2.1 -1.5 -1.9 1.2 -1.4 -1.5 -2.0 -1.8 -1.2 -0.2 -1.4 -2.0 -1.7 -1.5 -1.0 -1.8 -0.9 -0.7 -0.3 -0.1 -1.0 -1.1
Long-standing illness, disability or infirmity 1.0 1.5 5.2 0.1 -1.4 -0.8 -1.1 -0.8 -0.7 -1.3 -0.9 1.8 0.5 -0.7 -1.0 -0.7 1.6 -0.8 -0.7 0.8 -1.2 1.1 -1.5 -0.9 -1.9 -2.3 0.6 -1.3 -1.7 -1.8
Ever had bowel cancer screening 2.0 2.4 6.5 -1.9 -1.6 -1.6 -1.8 -1.5 -1.8 -1.6 -1.3 1.7 -0.9 -1.5 -1.6 -1.8 -0.8 -1.8 -1.9 -1.2 -0.8 -0.5 -1.5 -1.5 -1.5 -2.5 0.8 -1.8 -1.6 -1.5
Diabetes diagnosed by doctor 0.8 1.2 3.3 -1.0 -1.8 -1.6 -1.4 -1.5 -1.3 -0.9 -0.7 1.3 -0.9 -1.3 -0.8 -1.2 0.3 -0.4 -1.2 -0.7 -0.9 -0.3 -0.3 -1.2 -1.7 -0.4 -0.3 -0.3 -1.7 -1.7
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.6 4.5 -0.5 -0.2 -0.6 -0.5 -0.9 -0.7 0.0 0.3 0.3 -1.4 -0.1 -0.7 -0.6 -0.9 0.4 -0.6 -0.4 -0.5 0.2 -1.0 -0.5 -0.1 -0.9 -2.1 1.5 -0.4 -0.2
Friendships satisfaction 0.2 0.3 1.2 0.2 -0.4 -0.5 0.1 -0.7 -0.1 -0.3 -0.9 0.1 -0.3 -0.2 -0.5 0.0 -0.1 0.7 0.4 -0.8 -0.8 -0.9 0.3 -0.6 -0.2 -1.0 -1.1 0.5 0.2 -0.3
Qualifications: nursing, teaching 0.7 1.0 2.4 0.5 1.3 1.2 1.1 1.0 1.0 0.6 0.7 -1.3 0.7 1.3 0.9 1.0 0.4 0.7 1.1 0.8 1.3 0.4 -0.2 1.4 1.3 1.5 -0.0 1.2 1.2 1.4
Commuting to job workplace: Walk 0.9 0.9 4.8 0.1 -0.7 -0.3 -0.6 -0.4 -0.1 -1.0 -1.1 1.1 -0.4 -0.3 -0.3 -0.1 1.1 0.7 -0.2 0.2 -1.0 1.4 -0.2 -0.2 -1.8 -0.6 -2.2 0.3 -2.2 -1.6
Eye problems/disorders: Cataract 0.4 0.4 6.0 0.0 -0.1 0.2 0.4 0.2 0.4 -0.3 -0.8 0.1 -0.2 0.2 -0.0 0.6 0.3 0.6 0.5 0.0 -0.6 0.3 0.2 0.0 -0.1 -0.9 -2.5 1.2 -0.2 -0.1
Mouth/teeth dental problems: Mouth ulcers 0.5 0.8 2.6 -1.6 -1.4 -0.8 -1.1 -0.9 -1.0 -1.4 -1.0 0.4 0.1 -1.0 -0.7 -1.0 -0.1 -1.2 -1.0 -0.4 -0.2 0.3 0.4 -0.3 -0.8 0.7 -0.3 -1.1 -1.4 -0.8
Medication for cholesterol 2.2 3.4 9.5 1.8 1.9 2.0 2.2 1.8 2.0 1.6 1.4 -1.8 1.7 2.0 2.2 2.1 0.9 1.1 1.9 1.4 1.2 1.2 0.5 1.9 1.9 1.6 -3.1 2.5 1.8 1.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 3.0 0.9 1.0 0.8 0.8 1.2 1.0 0.4 -0.0 -0.8 0.8 0.6 1.7 0.9 -0.1 -0.2 0.6 0.2 0.6 0.1 1.2 1.0 0.4 -0.4 -1.3 0.4 0.5 0.5
Back pain experienced in last month 1.6 2.4 4.8 -2.1 -1.5 -1.9 -1.9 -2.1 -2.1 -1.1 -0.9 1.0 -0.6 -1.8 -1.9 -2.2 -2.2 -0.4 -1.9 -1.8 -1.4 -1.0 -1.3 -2.0 -0.5 -1.5 -0.8 -1.2 -0.8 -0.8
Mineral and other dietary supplements 2.5 3.4 7.9 1.1 1.4 2.1 2.5 1.9 1.9 1.1 1.7 -2.2 2.0 2.4 2.3 2.2 0.0 -0.2 2.4 0.9 1.4 -0.9 0.6 1.9 2.4 0.1 -1.3 2.7 2.8 2.4
Breast cancer (self-reported) 1.1 1.3 6.9 0.0 -0.7 0.1 0.2 -0.0 0.3 -0.1 -0.5 1.1 1.4 0.5 0.0 0.5 2.6 0.6 0.5 1.4 -1.4 1.7 -1.3 -0.2 -1.0 -2.5 -1.7 1.5 -0.6 -1.0
Asthma (self-reported) 0.4 0.9 2.2 -0.4 -0.8 -1.0 -0.8 -0.8 -0.7 -0.9 -1.4 1.2 -1.4 -1.1 -1.2 -0.6 0.3 0.4 -0.6 -0.9 -1.1 -0.6 0.4 -1.1 -1.5 -0.3 0.2 -0.8 -1.2 -1.4
Osteoporosis (self-reported) 0.8 0.9 3.7 0.0 -0.2 -0.4 -1.3 -0.4 -0.7 -0.4 -0.4 1.3 -0.3 -0.8 -0.7 -1.1 0.8 1.0 -1.0 0.8 -0.4 1.9 -0.9 -0.2 -1.3 -0.1 1.3 -1.8 -1.4 -1.2
Osteoarthritis (self-reported) 0.3 0.4 1.7 1.1 -0.1 0.5 0.2 0.9 0.7 -0.1 -0.3 0.2 0.3 -0.0 0.4 0.5 0.6 -0.8 0.3 0.6 0.5 1.0 1.3 0.5 -0.8 -0.5 0.5 -0.5 -0.6 -0.6
Medication: Aspirin 1.1 1.5 4.1 1.7 0.8 1.5 1.0 1.6 1.3 1.5 1.9 -0.1 2.0 1.2 1.3 1.2 1.4 0.7 1.3 1.7 1.1 0.6 0.1 1.1 0.1 1.5 1.2 0.2 -0.4 0.2
Medication: Gliclazide 1.1 1.3 2.6 -0.1 -1.5 -1.4 -1.1 -1.3 -1.1 -0.9 -1.3 1.4 -1.3 -1.1 -0.9 -0.9 -0.6 -0.2 -0.9 -1.3 -1.3 -1.3 -0.7 -1.5 -1.4 -1.6 -0.6 0.0 -1.1 -1.5
Illnesses of father: None of the above (group 1) 1.1 1.4 3.7 -0.5 1.7 1.0 0.8 0.6 0.4 1.4 1.5 -1.6 1.6 1.2 1.0 0.4 -0.3 0.1 0.7 0.7 1.9 1.0 -0.2 1.4 1.9 1.3 -0.9 0.5 1.9 1.9
Smoking status: Current 0.3 0.4 2.0 0.2 -0.6 0.2 0.4 0.4 0.3 0.4 0.2 0.9 1.1 0.4 0.6 0.6 1.4 0.0 0.5 0.5 -1.0 -0.2 -0.5 -0.2 -0.7 -0.0 -0.7 1.3 -0.3 -0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.7 5.6 10.8 2.0 3.1 3.1 3.3 2.8 2.9 2.0 1.0 -2.7 1.2 3.3 2.0 3.0 1.5 0.0 3.1 2.2 1.8 0.2 0.3 2.8 3.0 1.1 -0.1 2.5 3.2 3.1
Whole body water mass 0.3 1.7 7.1 -0.3 -1.6 -1.4 -1.1 -1.0 -1.1 -1.3 -1.2 0.5 -0.6 -1.7 -0.7 -1.2 -1.3 -2.0 -1.2 -1.7 -1.2 -2.7 0.9 -1.4 -0.8 -0.5 2.4 -1.0 -0.5 -0.9
Leg predicted mass (right) 0.1 0.7 5.6 0.9 -0.1 0.0 0.2 0.4 0.3 -0.1 0.1 -0.9 0.4 -0.4 0.7 0.0 -0.8 -1.7 0.0 -0.6 0.5 -1.8 1.8 0.2 0.4 0.5 2.4 -0.6 0.4 0.4
Arm fat mass (left) 0.1 0.5 5.4 0.4 -0.2 0.0 0.1 0.2 0.0 -0.1 -0.5 -0.6 0.8 -0.3 0.2 -0.1 -0.5 -1.6 0.1 -0.3 0.2 -1.4 0.8 0.1 0.5 -0.5 2.3 -0.3 0.5 0.5
Number of self-reported non-cancer illnesses 2.2 3.8 8.3 -0.7 -2.5 -2.0 -2.2 -1.6 -1.7 -2.1 -2.4 2.6 -0.9 -2.2 -1.9 -1.7 0.4 -1.7 -1.8 -1.0 -2.0 -0.5 -0.5 -2.0 -2.9 -1.6 1.4 -2.6 -2.8 -2.9
Average weekly champagne plus white wine intake 1.6 2.3 7.4 -1.6 -1.5 -1.5 -1.9 -1.7 -1.9 -0.9 -0.5 2.2 -1.0 -1.2 -1.8 -1.8 0.5 1.3 -1.8 -0.4 -1.5 0.3 -2.7 -1.6 -1.8 -0.7 -0.1 -1.4 -1.5 -1.8
Miserableness 0.5 0.8 4.5 0.0 -1.1 -0.5 -0.6 -0.4 -0.3 -1.1 -1.0 1.1 0.1 -0.8 -0.7 -0.3 1.0 -2.1 -0.2 -0.2 -1.0 -0.3 0.7 -0.5 -1.6 -0.0 1.1 -0.5 -1.6 -1.5
Guilty feelings 0.7 1.1 2.6 -1.0 -0.8 -1.0 -1.4 -0.9 -0.9 -0.9 -1.1 1.2 -0.1 -1.3 -0.9 -1.2 0.5 -1.1 -1.1 0.1 -1.1 0.8 -0.1 -0.9 -1.4 -0.3 1.2 -1.0 -1.6 -1.4
Wears glasses or contact lenses 0.6 0.6 2.9 -0.3 -0.8 -0.1 -0.6 -0.0 -0.2 -0.3 -0.6 1.3 -0.3 0.1 -0.5 -0.1 1.0 0.8 -0.2 0.7 -0.2 1.0 -1.0 -0.2 -1.5 -1.4 -0.5 -0.6 -1.7 -1.4
Ever taken oral contraceptive pill 0.4 0.4 1.5 -1.0 -0.5 -0.8 -0.6 -1.2 -0.9 -0.7 -0.3 0.3 -0.4 -0.3 -0.7 -0.7 -0.9 0.3 -0.6 -0.7 -0.4 -0.2 -1.2 -0.7 -0.1 -1.1 -0.8 -0.0 -0.3 -0.2
Hearing aid user 0.8 0.9 2.0 1.0 1.1 1.0 1.0 1.0 1.1 0.7 0.5 -1.3 0.7 0.9 0.9 0.9 0.2 0.7 0.9 0.9 1.4 1.2 1.3 1.3 0.9 0.4 -0.2 0.4 0.8 1.0
Mother’s age at death 2.0 2.5 5.2 -1.2 -1.4 -2.2 -1.8 -2.1 -2.1 -0.9 -0.5 1.2 -1.6 -2.2 -2.1 -2.1 -1.9 -1.2 -1.9 -2.2 -0.9 -1.6 -0.8 -2.3 -0.8 -1.4 1.0 -1.4 -0.2 -1.0
Financial situation satisfaction 0.2 0.3 1.7 -0.5 -0.4 -0.3 0.2 -0.4 -0.3 -0.4 -0.7 -0.4 0.1 -0.2 -0.3 -0.1 -0.5 -1.3 0.2 -0.7 -0.3 -0.6 0.3 -0.3 0.6 -0.5 -0.8 0.3 1.0 0.4
Tinnitus: Yes, now most or all of the time 0.7 0.8 2.5 0.3 -0.8 -0.9 -0.9 -0.8 -0.6 0.1 0.5 1.6 0.0 -0.8 -0.7 -0.6 0.9 0.7 -0.5 0.2 -1.2 -0.4 -0.7 -1.1 -1.6 0.2 1.5 -0.1 -1.2 -1.6
Commuting to job workplace: Public transport 0.3 0.4 2.1 -0.4 0.4 0.1 -0.3 0.0 -0.1 0.7 0.8 -0.3 1.2 0.1 0.6 -0.3 -0.1 0.4 -0.4 0.6 1.2 1.4 0.3 0.6 0.0 0.2 -0.6 -1.4 -0.2 0.1
Eye problems/disorders: Glaucoma 1.4 1.7 4.8 -1.3 -1.2 -1.6 -1.6 -1.7 -1.6 -1.2 -1.2 0.7 -1.0 -1.8 -1.6 -1.7 -1.5 -2.2 -1.6 -1.5 -1.2 -0.5 0.2 -1.3 -0.9 -0.7 -0.1 -0.8 -0.8 -1.0
Medication: Blood pressure 2.2 4.2 9.8 -1.6 -1.8 -2.1 -2.3 -1.9 -2.2 -1.8 -2.3 2.0 -1.9 -2.2 -2.8 -2.2 -1.5 -1.6 -2.0 -2.0 -1.9 -1.9 -0.7 -2.3 -1.8 -2.0 3.1 -2.4 -1.8 -2.0
Pain type(s) experienced in last month: Hip pain 1.2 1.5 2.8 -1.0 -1.4 -1.5 -1.2 -1.6 -1.4 -1.4 -1.6 1.2 -0.5 -1.3 -1.7 -1.3 -0.1 -1.3 -1.1 -1.0 -1.6 -1.0 -0.8 -1.7 -0.9 -1.3 0.6 -0.9 -0.7 -1.1
Supplements: Fish oil (including cod liver oil) 2.0 2.6 6.3 -1.1 -1.0 -1.7 -2.1 -1.4 -1.6 -1.2 -1.8 1.6 -1.9 -2.3 -2.0 -1.9 -0.8 -1.4 -2.2 -1.4 -0.9 0.1 0.3 -1.6 -1.8 0.2 1.4 -2.5 -2.1 -1.8
High cholesterol (Self-reported) 0.3 0.5 1.7 0.1 -0.5 -0.3 -0.4 -0.1 -0.2 -0.2 -0.2 1.1 -0.3 -0.1 -0.2 -0.1 1.2 1.2 -0.0 0.5 -0.6 0.3 -0.5 -0.3 -1.3 -1.2 0.6 -0.4 -1.3 -1.2
Medication: Bendroflumethiazide 1.7 2.5 4.4 -1.5 -1.5 -1.7 -1.9 -1.7 -1.9 -1.2 -1.7 1.7 -1.0 -1.7 -2.1 -1.9 -1.2 -0.4 -1.6 -1.7 -1.6 -1.5 -1.5 -1.8 -1.5 -1.8 0.8 -1.8 -1.3 -1.6
Medication: Paracetamol 0.2 0.3 2.8 0.1 -0.2 0.3 0.4 0.5 0.2 -0.5 -0.7 -0.1 0.5 0.2 0.1 0.4 -0.5 -0.3 0.3 -0.6 -0.1 -0.3 -0.1 0.1 0.1 -1.7 -0.9 0.7 0.2 0.1
Medication: Lisinopril 1.7 2.2 5.0 1.1 1.4 1.9 1.7 2.1 1.6 1.3 0.8 -2.0 1.7 1.6 1.5 1.5 0.1 -0.1 1.7 1.2 2.2 0.4 1.3 2.2 1.8 1.1 0.3 1.1 1.5 2.0
Medication: Atorvastatin 0.5 0.6 2.5 -0.5 -0.5 -0.7 -0.9 -0.7 -0.9 -0.2 0.1 1.0 -0.6 -0.6 -1.1 -1.0 0.2 -0.2 -0.8 -0.2 -0.3 0.2 -1.6 -0.8 -0.6 -0.9 -0.4 -1.4 -0.7 -0.7
Illnesses of father: High blood pressure 0.7 0.9 2.9 1.2 0.6 0.8 1.5 0.8 1.3 0.2 0.4 -1.3 -0.2 1.0 1.1 1.4 0.2 0.5 1.3 0.2 0.7 -0.8 1.4 0.8 0.9 0.2 0.2 1.7 0.9 1.0
Alcohol drinker status: Never 0.4 0.5 3.5 -0.9 -0.4 -0.3 -0.4 -0.3 -0.5 0.3 -0.1 -0.5 -0.6 -0.5 -0.4 -0.6 -1.3 -1.9 -0.6 -0.9 0.3 -1.1 0.5 0.0 0.3 1.2 0.3 0.3 -0.0 0.3
Ever smoked 0.5 0.8 7.6 0.9 -0.2 0.2 -0.5 0.5 0.2 -0.5 0.9 0.8 0.7 -0.2 0.4 -0.2 1.3 0.8 -0.2 1.6 0.5 2.8 -0.2 0.3 -1.0 -0.6 -0.6 -1.7 -1.0 -0.8
Basal metabolic rate 0.3 1.8 7.2 -0.4 -1.6 -1.4 -1.1 -1.0 -1.1 -1.3 -1.2 0.4 -0.5 -1.7 -0.7 -1.2 -1.5 -2.2 -1.2 -1.8 -1.0 -2.7 1.0 -1.3 -0.6 -0.5 2.6 -1.1 -0.3 -0.7
Leg fat percentage (left) 0.2 0.8 2.9 -0.3 -0.9 -0.9 -0.8 -0.8 -0.8 -0.9 -1.1 0.3 0.4 -1.1 -0.7 -0.9 -0.8 -1.7 -0.8 -0.8 -0.5 -1.0 0.1 -0.8 -0.3 -1.4 1.7 -0.9 -0.3 -0.4
Arm fat-free mass (left) 0.5 2.4 9.3 -0.6 -1.9 -1.8 -1.5 -1.4 -1.4 -1.5 -1.3 1.0 -0.6 -2.0 -1.2 -1.6 -1.2 -1.8 -1.6 -1.8 -1.5 -2.6 0.4 -1.8 -1.1 -0.6 3.0 -1.2 -0.7 -1.2
Number of operations (self-reported) 1.0 1.5 4.0 -1.6 -1.1 -1.0 -1.5 -1.2 -1.5 -1.6 -1.1 1.3 -0.4 -1.0 -1.8 -1.6 -1.0 -0.3 -1.4 -0.6 -1.2 0.6 -1.6 -1.1 -0.8 -2.0 -1.5 -0.7 -1.0 -0.9
Average weekly beer plus cider intake 0.3 0.4 2.0 0.3 -0.4 0.1 -0.0 -0.0 0.1 0.1 0.8 0.8 0.1 0.3 -0.1 0.2 1.4 0.8 0.3 1.3 -0.6 1.2 -0.7 0.0 -0.7 -0.7 -0.9 0.2 -0.4 -0.7
Irritability 0.5 0.8 3.7 0.9 -0.1 -0.1 -0.8 0.2 0.1 1.1 1.4 0.7 0.1 -0.8 0.5 -0.4 0.3 -1.9 -0.6 0.4 0.4 0.8 1.1 -0.1 -1.2 1.0 0.9 -1.2 -1.7 -1.1
Risk taking 0.6 0.8 5.2 0.5 0.6 -0.2 0.4 -0.0 0.4 0.3 -0.4 -1.3 -1.3 -0.4 0.5 0.3 -1.2 -1.6 -0.0 -1.1 0.4 -0.3 2.3 0.3 0.7 0.5 -1.7 1.2 0.7 0.7
Ever had prostate specific antigen (PSA) test 0.3 0.4 2.8 -0.4 0.8 0.5 0.2 0.4 0.2 0.1 -0.1 -0.8 0.8 0.3 0.5 0.2 -0.4 0.7 0.2 0.1 1.0 0.9 0.6 0.8 0.6 0.2 -1.7 0.4 0.1 0.7
Fractured/broken bones in last 5 years 0.3 0.4 1.0 0.8 0.5 0.1 -0.4 0.3 0.2 0.6 1.0 0.9 0.6 -0.2 0.3 -0.2 0.5 0.8 -0.1 0.9 -0.2 0.8 -0.3 -0.2 -0.9 -0.2 0.7 -1.0 -1.0 -0.8
Age started oral contraceptive pill 0.2 0.3 1.3 0.6 0.1 0.5 0.7 0.7 0.9 0.3 -0.2 -0.3 -0.2 0.4 0.0 0.8 0.5 -0.0 0.5 0.2 0.1 -0.6 1.1 0.3 -0.2 1.1 0.8 -0.5 -0.3 -0.0
Diastolic blood pressure, automated reading 0.1 0.4 1.4 -0.3 -0.0 0.4 0.8 0.4 0.6 0.1 0.1 -0.7 0.9 0.7 0.8 0.8 -0.4 1.2 1.0 -0.2 0.7 -1.2 1.1 0.5 0.5 -0.1 0.2 0.2 0.2 0.5
Ever depressed for a whole week 1.8 2.3 4.5 -2.0 -1.9 -1.8 -1.8 -1.8 -1.9 -0.9 -0.9 1.8 -0.3 -1.6 -1.7 -1.7 -0.6 -0.3 -1.4 -1.5 -0.8 -0.6 -1.1 -1.7 -1.8 -2.1 0.2 -1.8 -1.6 -1.9
Unable to work because of sickness or disability 0.9 1.2 6.2 1.6 1.1 1.0 0.4 1.1 0.9 0.7 0.9 0.2 2.0 0.7 0.9 0.6 1.8 -0.7 0.6 2.1 0.9 2.5 -0.2 1.1 -0.4 -0.9 -0.4 -1.0 -0.6 -0.2
Commuting to job workplace: Cycle 1.6 1.9 5.9 -0.6 -1.2 -1.2 -1.7 -1.1 -1.3 -0.5 -0.8 2.4 -0.5 -1.4 -1.7 -1.2 1.0 0.4 -1.3 -0.2 -1.3 1.0 -1.2 -1.4 -2.4 -1.0 -0.7 -1.6 -2.1 -2.4
Myopia 0.2 0.3 1.6 0.7 0.3 0.2 0.0 0.1 0.2 0.3 1.2 -0.4 -0.5 0.1 0.5 0.0 -0.2 0.9 0.3 0.5 1.1 1.2 0.1 0.3 0.3 0.6 -0.5 -1.3 0.1 0.3
Vascular/heart problems diagnosed by doctor 0.1 0.3 2.5 -0.3 0.1 -0.1 0.3 -0.2 0.0 0.7 1.0 -0.4 -0.0 0.1 0.4 0.1 0.0 -0.3 -0.1 0.1 0.1 0.5 0.2 0.0 0.5 -0.2 -1.6 1.1 0.6 0.4
Cholesterol lowering medication 0.2 0.3 2.3 -0.9 -0.1 -0.3 -0.8 -0.1 -0.6 -0.0 -0.3 0.4 -0.3 -0.6 -0.6 -0.7 -0.5 0.5 -0.7 -0.3 0.1 0.1 0.0 -0.1 -0.5 -1.5 -0.3 -1.1 -0.6 -0.5
Medication: Omeprazole (e.g. Zanprol) 1.5 1.8 5.6 -0.1 -1.3 -1.3 -1.7 -1.5 -1.4 -0.8 0.2 1.9 -0.1 -1.3 -1.7 -1.6 0.3 -0.2 -1.5 0.2 -1.1 1.6 -2.4 -1.5 -1.2 -1.7 0.2 -2.3 -1.0 -1.3
Pain experienced in last month 0.4 0.7 4.7 0.7 0.6 0.6 -0.0 0.8 0.5 0.3 0.6 0.5 0.1 0.2 0.5 0.4 1.6 1.3 0.1 1.2 0.3 1.3 0.4 0.7 -1.0 2.2 0.6 -0.5 -0.9 -0.7
Supplements: Calcium 2.0 2.2 4.2 -1.6 -1.6 -1.9 -2.0 -1.8 -1.8 -1.1 -0.8 1.6 -1.8 -1.9 -1.4 -1.9 -0.9 0.4 -1.8 -1.2 -1.1 -0.1 -0.8 -1.6 -1.7 -1.1 0.1 -1.1 -1.8 -1.8
Basal cell carcinoma (self-reported) 0.1 0.2 1.4 -0.5 -0.0 -0.1 -0.2 0.0 -0.3 0.0 -0.4 -0.2 0.2 -0.3 -0.1 -0.3 -0.6 -1.2 -0.4 -0.5 0.4 -0.7 0.2 0.2 0.2 0.3 0.8 -0.0 -0.1 0.2
Heart attack/myocardial infarction (self-reported) 0.6 0.8 2.2 0.9 0.6 1.3 0.9 1.5 1.1 0.6 0.6 0.1 1.4 1.2 1.0 1.2 1.5 0.8 1.0 1.2 0.5 0.6 -0.5 1.0 -0.0 0.5 0.5 0.6 -0.3 0.1
Deep venous thrombosis (DVT) (self-reported) 1.5 2.0 5.2 1.1 1.7 1.4 1.3 1.5 1.4 1.3 1.0 -2.3 0.9 1.1 1.4 1.1 -1.1 -0.5 1.2 0.4 2.2 0.1 1.9 1.8 1.9 1.1 0.8 1.0 1.9 2.0
Heart disease (siblings) 0.2 0.3 1.2 -1.1 -0.5 -0.4 -0.2 -0.6 -0.4 -0.7 -0.0 0.5 0.4 0.1 0.1 -0.2 -0.2 0.5 -0.4 -0.1 -0.9 -0.6 -0.7 -0.5 -0.3 -0.8 0.3 0.6 -0.4 -0.3
Alcohol drinker status: Previous 0.6 0.7 5.8 0.4 0.4 0.4 -0.2 0.4 0.2 -1.2 -1.7 -0.2 0.1 -0.1 -0.3 -0.2 0.4 -1.2 -0.2 1.0 -0.3 2.4 0.1 0.6 0.3 -1.3 -1.1 -0.8 0.0 0.3
Pack years of smoking 1.5 2.2 9.2 -2.3 -1.4 -1.3 -0.4 -0.9 -1.0 -1.2 -1.4 -0.3 -1.2 -1.2 -0.4 -0.7 -2.3 -3.0 -0.8 -2.6 -1.2 -3.0 1.7 -1.3 0.4 -1.3 0.2 1.0 0.7 0.1
Impedance of whole body 0.6 3.3 7.0 -2.4 -1.9 -1.9 -2.4 -2.1 -2.2 -1.6 -0.8 2.4 -0.5 -1.6 -1.5 -2.1 -0.3 1.3 -2.1 -0.9 -1.4 1.5 -2.6 -1.8 -2.2 -1.2 -1.7 -1.3 -2.2 -2.2
Leg fat mass (left) 0.3 1.0 6.5 -0.1 -0.9 -0.9 -0.7 -0.6 -0.8 -1.0 -1.2 0.0 0.2 -1.2 -0.6 -1.0 -1.1 -2.0 -0.8 -1.1 -0.5 -1.7 0.5 -0.8 -0.1 -1.0 2.5 -0.7 0.0 -0.2
Arm predicted mass (left) 0.6 2.9 9.6 -0.7 -2.0 -2.0 -1.7 -1.6 -1.6 -1.7 -1.5 1.0 -0.9 -2.2 -1.4 -1.8 -1.4 -2.4 -1.8 -2.0 -1.7 -2.6 0.4 -1.9 -1.2 -0.7 3.1 -1.2 -0.8 -1.3