Best TWAS P=3.37e-17 · Best GWAS P=5.85e-19 conditioned to 0.00399
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | PAPD7 | 0.13 | 0.07 | lasso | 3 | 0.04 | 2.2e-04 | -5.5 | 5.5 | 2.9e-08 | 0.50 | 0.62 | 0.04 | FALSE |
2 | GTEx | Testis | PAPD7 | 0.36 | 0.22 | lasso | 7 | 0.22 | 3.4e-10 | 8.9 | 8.4 | 3.4e-17 | 0.93 | 0.01 | 0.99 | TRUE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | PAPD7 | 0.09 | 0.08 | lasso | 5 | 0.10 | 7.0e-10 | -5.5 | -7.8 | 4.4e-15 | -0.77 | 0.04 | 0.96 | FALSE |