[Hub]/) : Traits : Height :

chr5:12,225-1,462,720

Best TWAS P=1.18e-27 · Best GWAS P=9.4e-27 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AHRR 0.25 0.18 lasso 12 0.21 1.2e-25 9.03 9.4 7.5e-21 0.49 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex SDHA 0.12 0.06 bslmm 290 0.11 8.6e-14 8.94 -9.5 2.4e-21 -0.58 1.00 0.00 FALSE
3 GTEx Adipose Subcutaneous SDHA 0.10 0.09 lasso 5 0.07 1.9e-06 9.03 9.5 2.5e-21 0.53 0.98 0.00 FALSE
4 GTEx Adipose Subcutaneous CCDC127 0.07 0.00 lasso 4 0.00 2.1e-01 5.05 7.7 1.1e-14 0.42 0.07 0.70 TRUE
5 GTEx Adipose Visceral Omentum SDHA 0.10 0.05 lasso 3 0.07 1.5e-04 9.17 9.1 1.2e-19 0.48 0.30 0.12 FALSE
6 GTEx Adipose Visceral Omentum CCDC127 0.13 0.03 lasso 4 0.05 9.0e-04 9.95 10.9 1.2e-27 0.74 0.03 0.95 TRUE
7 GTEx Artery Aorta PDCD6 0.26 0.17 lasso 4 0.14 2.8e-08 9.03 -8.4 3.0e-17 -0.52 0.99 0.00 FALSE
8 GTEx Artery Coronary CCDC127 0.27 0.02 lasso 7 0.00 2.7e-01 6.52 7.6 3.1e-14 0.45 0.02 0.61 FALSE
9 GTEx Artery Tibial PDCD6 0.22 0.07 lasso 4 0.06 2.1e-05 9.03 -7.4 1.7e-13 -0.50 0.66 0.29 FALSE
10 GTEx Brain Cerebellum CTD-2083E4.5 0.14 0.01 lasso 10 0.03 5.9e-02 6.09 -7.5 7.0e-14 -0.30 0.10 0.12 FALSE
11 GTEx Brain Frontal Cortex BA9 AHRR 0.32 0.21 lasso 4 0.18 1.6e-05 9.03 8.3 1.3e-16 0.51 0.12 0.06 TRUE
12 GTEx Cells Transformed fibroblasts SDHA 0.23 0.18 lasso 2 0.17 1.6e-12 9.03 9.1 1.4e-19 0.53 1.00 0.00 FALSE
13 GTEx Cells Transformed fibroblasts CCDC127 0.25 0.13 lasso 5 0.14 9.0e-11 7.06 9.2 2.8e-20 0.49 0.81 0.19 FALSE
14 GTEx Cells Transformed fibroblasts CTD-2083E4.5 0.09 0.07 lasso 3 0.05 1.2e-04 9.17 -8.7 3.9e-18 -0.52 0.42 0.11 FALSE
15 GTEx Colon Sigmoid SLC9A3 0.18 0.05 enet 16 0.09 5.1e-04 -0.54 -5.5 3.7e-08 -0.22 0.06 0.20 FALSE
16 GTEx Esophagus Gastroesophageal Junction CCDC127 0.13 0.09 lasso 3 0.03 2.8e-02 7.18 7.0 1.9e-12 0.53 0.08 0.16 FALSE
17 GTEx Esophagus Gastroesophageal Junction PDCD6 0.22 0.17 lasso 3 0.19 1.8e-07 7.06 -6.0 1.6e-09 -0.36 0.19 0.45 FALSE
18 GTEx Esophagus Gastroesophageal Junction CTD-2083E4.5 0.25 0.11 enet 10 0.12 3.3e-05 -0.16 -5.1 3.1e-07 -0.25 0.28 0.13 FALSE
19 GTEx Heart Atrial Appendage SDHA 0.15 0.04 lasso 3 0.02 4.3e-02 9.95 -10.3 6.3e-25 -0.82 0.02 0.94 FALSE
20 GTEx Muscle Skeletal ZDHHC11B 0.11 0.01 enet 16 0.03 4.0e-04 5.77 6.6 4.9e-11 0.25 0.37 0.03 FALSE
21 GTEx Muscle Skeletal PDCD6 0.08 0.04 lasso 6 0.01 1.8e-02 8.93 -6.7 2.8e-11 -0.49 0.07 0.80 FALSE
22 GTEx Nerve Tibial CCDC127 0.05 0.01 lasso 4 0.02 2.2e-02 9.95 10.4 3.1e-25 0.80 0.04 0.80 FALSE
23 GTEx Pancreas EXOC3 0.15 0.09 lasso 4 0.14 2.0e-06 -3.36 5.6 2.0e-08 0.21 0.60 0.02 TRUE
24 GTEx Testis SDHA 0.33 0.24 lasso 7 0.20 2.9e-09 5.77 8.6 7.4e-18 0.33 0.99 0.00 FALSE
25 GTEx Thyroid EXOC3 0.16 0.04 lasso 5 0.06 3.6e-05 7.42 7.2 4.4e-13 0.28 0.82 0.01 FALSE
26 GTEx Thyroid PDCD6 0.33 0.05 enet 39 0.22 1.6e-16 8.93 -5.8 8.2e-09 -0.55 0.82 0.18 FALSE
27 GTEx Thyroid CTD-2083E4.5 0.07 0.06 lasso 2 0.04 3.6e-04 9.10 -9.6 9.1e-22 -0.53 0.31 0.12 TRUE
28 GTEx Whole Blood SDHA 0.05 0.01 lasso 5 0.01 3.4e-02 8.05 -8.5 1.5e-17 -0.62 0.23 0.30 FALSE
29 METSIM Adipose CTD-2228K2.5 0.05 0.01 blup 315 0.02 1.4e-04 5.50 6.3 3.6e-10 0.23 0.16 0.02 TRUE
30 METSIM Adipose PDCD6 0.09 0.04 lasso 9 0.05 1.5e-07 -7.34 6.8 8.4e-12 0.19 1.00 0.00 TRUE
31 METSIM Adipose SDHA 0.09 0.04 lasso 12 0.03 8.5e-06 8.94 8.6 8.3e-18 0.55 1.00 0.00 FALSE
32 NTR Blood CCDC127 0.02 0.01 blup 284 0.02 1.5e-06 7.18 -9.7 4.1e-22 -0.45 0.87 0.08 FALSE
33 NTR Blood LOC100288152 0.01 0.01 blup 318 0.01 2.6e-04 4.43 -5.9 4.7e-09 -0.24 0.52 0.07 FALSE
34 ROSMAP Brain Pre-frontal Cortex AHRR 0.35 0.19 enet 29 0.28 1.4e-36 2.63 7.3 3.1e-13 0.36 1.00 0.00 FALSE
35 ROSMAP Brain Pre-frontal Cortex SDHA 0.07 0.04 lasso 4 0.04 2.3e-06 7.18 -7.8 4.3e-15 -0.25 0.94 0.01 FALSE
36 ROSMAP Brain Pre-frontal Cortex CCDC127 0.19 0.18 lasso 6 0.19 3.3e-24 7.85 -6.4 1.9e-10 -0.19 1.00 0.00 TRUE
37 ROSMAP Brain Pre-frontal Cortex EXOC3 0.40 0.32 enet 19 0.36 5.3e-49 -2.77 5.2 1.7e-07 0.35 1.00 0.00 FALSE
38 ROSMAP Brain Pre-frontal Cortex ZDHHC11B 0.05 0.00 bslmm 350 0.02 4.9e-04 9.70 5.4 5.8e-08 0.39 0.04 0.23 FALSE
39 YFS Blood PDCD6 0.03 0.03 bslmm 276 0.03 1.6e-09 9.03 10.7 1.5e-26 0.60 1.00 0.00 FALSE
40 The Cancer Genome Atlas Breast Invasive Carcinoma AHRR 0.04 0.03 lasso 3 0.03 1.1e-06 7.85 10.7 8.9e-27 0.68 0.02 0.98 FALSE
41 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma AHRR 0.10 0.01 blup 100 0.05 2.4e-06 8.05 6.4 1.9e-10 0.37 0.09 0.27 TRUE
42 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LRRC14B 0.04 0.02 blup 63 0.01 2.0e-02 3.54 6.0 1.5e-09 0.21 0.09 0.26 FALSE
43 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PDCD6 0.03 0.02 blup 49 0.02 2.9e-03 8.94 9.2 2.8e-20 0.66 0.36 0.10 FALSE
44 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SDHA 0.04 0.03 blup 62 0.05 3.3e-06 9.03 9.6 1.0e-21 0.49 0.80 0.11 FALSE
45 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma AHRR 0.09 0.01 blup 100 0.06 2.7e-04 -7.34 7.8 4.2e-15 0.32 0.05 0.20 FALSE
46 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CCDC127 0.10 0.05 enet 7 0.06 4.0e-04 7.06 6.0 2.2e-09 0.38 0.02 0.59 FALSE
47 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LRRC14B 0.08 0.04 lasso 5 0.03 6.7e-03 8.94 8.9 3.9e-19 0.58 0.01 0.96 FALSE
48 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SDHA 0.05 0.02 lasso 4 0.01 1.3e-01 7.12 8.8 1.1e-18 0.47 0.08 0.25 FALSE
49 The Cancer Genome Atlas Brain Lower Grade Glioma AHRR 0.30 0.17 lasso 3 0.25 7.9e-28 7.85 10.2 1.9e-24 0.65 0.99 0.01 FALSE
50 The Cancer Genome Atlas Liver Hepatocellular Carcinoma AHRR 0.11 0.05 lasso 3 0.07 2.5e-04 9.03 9.2 2.5e-20 0.42 0.13 0.06 TRUE
51 The Cancer Genome Atlas Lung Adenocarcinoma AHRR 0.05 0.01 blup 99 0.01 1.4e-02 3.74 8.1 8.2e-16 0.35 0.10 0.30 FALSE
52 The Cancer Genome Atlas Prostate Adenocarcinoma AHRR 0.12 0.04 blup 99 0.05 9.0e-06 3.74 6.1 1.2e-09 0.15 0.98 0.00 FALSE
53 The Cancer Genome Atlas Stomach Adenocarcinoma AHRR 0.04 0.03 blup 100 0.04 9.1e-04 3.22 8.3 1.3e-16 0.37 0.05 0.40 FALSE
54 The Cancer Genome Atlas Thyroid Carcinoma AHRR 0.13 0.04 blup 100 0.08 1.3e-08 7.85 6.8 7.8e-12 0.33 0.90 0.04 FALSE
55 The Cancer Genome Atlas Thyroid Carcinoma CCDC127 0.05 0.02 enet 7 0.04 5.3e-05 9.10 7.0 2.1e-12 0.48 0.01 0.97 FALSE
56 The Cancer Genome Atlas Thyroid Carcinoma PDCD6 0.07 0.06 enet 5 0.07 2.0e-07 9.10 -7.5 7.6e-14 -0.53 0.89 0.08 FALSE
57 The Cancer Genome Atlas Thyroid Carcinoma SDHA 0.06 0.09 lasso 13 0.08 1.8e-08 9.03 9.0 3.4e-19 0.54 0.86 0.14 FALSE