Best TWAS P=2.77e-10 · Best GWAS P=8.29e-15 conditioned to 1.06e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pancreas | SMIM15 | 0.10 | 0.03 | enet | 22 | 0.05 | 3.8e-03 | -3.6 | 6.3 | 2.8e-10 | -0.01 | 0.07 | 0.23 | TRUE |
| 2 | GTEx | Stomach | ELOVL7 | 0.15 | 0.14 | enet | 14 | 0.16 | 4.7e-08 | -4.7 | 5.2 | 2.0e-07 | -0.04 | 0.01 | 0.97 | FALSE |
| 3 | YFS | Blood | PDE4D | 0.04 | 0.01 | bslmm | 1054 | 0.01 | 1.8e-05 | -2.5 | -5.2 | 1.8e-07 | 0.20 | 0.53 | 0.07 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C5orf43 | 0.06 | 0.05 | blup | 29 | 0.06 | 1.8e-06 | -5.0 | 5.7 | 1.2e-08 | -0.04 | 0.00 | 0.99 | FALSE |