Best TWAS P=1.48e-17 · Best GWAS P=1.07e-29 conditioned to 1.09e-14
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | PIK3R1 | 0.05 | 0.00 | blup | 514 | 0.00 | 0.073 | -8.2 | -5.2 | 2.3e-07 | 0.35 | 0.02 | 0.68 | FALSE |
2 | The Cancer Genome Atlas | Glioblastoma Multiforme | PIK3R1 | 0.23 | 0.03 | lasso | 4 | 0.04 | 0.020 | -9.2 | -8.5 | 1.5e-17 | 0.61 | 0.04 | 0.41 | TRUE |