Best TWAS P=4.22e-25 · Best GWAS P=2.8e-26 conditioned to 0.000703
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | FCHO2 | 0.14 | 0.03 | enet | 59 | 0.02 | 0.00590 | 7.5 | 7.7 | 1.6e-14 | 0.55 | 0.10 | 0.77 | TRUE |
| 2 | GTEx | Pancreas | FCHO2 | 0.11 | 0.04 | enet | 7 | 0.03 | 0.01750 | 7.7 | 5.2 | 2.2e-07 | 0.39 | 0.26 | 0.04 | FALSE |
| 3 | GTEx | Testis | FCHO2 | 0.13 | 0.06 | lasso | 8 | 0.06 | 0.00137 | 9.5 | 10.3 | 4.2e-25 | 0.50 | 0.38 | 0.06 | TRUE |
| 4 | The Cancer Genome Atlas | Rectum Adenocarcinoma | FCHO2 | 0.32 | 0.16 | blup | 84 | 0.21 | 0.00001 | -7.6 | -5.4 | 5.3e-08 | -0.01 | 0.53 | 0.03 | FALSE |
| 5 | The Cancer Genome Atlas | Soft Tissue Sarcoma | FCHO2 | 0.06 | 0.04 | blup | 84 | 0.05 | 0.00089 | -7.6 | -5.6 | 1.7e-08 | 0.04 | 0.47 | 0.02 | TRUE |