Best TWAS P=6.95e-30 · Best GWAS P=7.43e-42 conditioned to 1.22e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FER | 0.10 | 0.01 | enet | 34 | 0.04 | 4.6e-06 | 1.0 | -5.8 | 5.8e-09 | -0.21 | 0.20 | 0.36 | FALSE |
| 2 | GTEx | Artery Aorta | FER | 0.23 | 0.15 | enet | 7 | 0.18 | 3.3e-10 | 10.8 | 11.4 | 7.0e-30 | 0.54 | 0.57 | 0.42 | TRUE |
| 3 | GTEx | Artery Coronary | FER | 0.34 | 0.10 | lasso | 8 | 0.12 | 5.4e-05 | -8.2 | 10.0 | 2.0e-23 | 0.56 | 0.16 | 0.27 | FALSE |
| 4 | GTEx | Artery Tibial | FER | 0.14 | 0.06 | enet | 7 | 0.05 | 7.3e-05 | -8.2 | 10.7 | 7.7e-27 | 0.67 | 0.17 | 0.82 | TRUE |
| 5 | GTEx | Lung | LINC01023 | 0.11 | 0.02 | enet | 16 | 0.01 | 9.3e-02 | -4.6 | -9.2 | 5.0e-20 | -0.42 | 0.09 | 0.24 | TRUE |