[Hub]/) : Traits : Height :

chr6:104,478,130-106,323,464

Best TWAS P=7.49e-100 · Best GWAS P=9.07e-180 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HACE1 0.14 0.10 enet 28 0.11 8.9e-14 6.84 -11.0 3.0e-28 -0.42 1.00 0.00 TRUE
2 CommonMind Brain Pre-frontal Cortex LIN28B 0.04 0.04 lasso 9 0.03 3.9e-05 22.73 21.2 7.5e-100 0.74 0.16 0.83 TRUE
3 CommonMind Brain Pre-frontal Cortex POPDC3 0.06 0.03 bslmm 386 0.02 1.0e-03 6.04 -12.1 1.3e-33 -0.31 0.19 0.09 TRUE
4 GTEx Brain Cerebellar Hemisphere HACE1 0.36 0.43 enet 19 0.39 5.8e-11 6.65 -7.6 2.9e-14 -0.30 1.00 0.00 FALSE
5 GTEx Brain Cerebellum HACE1 0.28 0.28 enet 16 0.26 3.6e-08 6.65 -7.8 4.5e-15 -0.31 0.98 0.00 TRUE
6 GTEx Brain Frontal Cortex BA9 HACE1 0.25 0.21 enet 22 0.18 1.7e-05 6.65 -7.0 3.2e-12 -0.31 0.52 0.08 FALSE
7 GTEx Breast Mammary Tissue (Female) BVES 0.07 0.01 lasso 3 0.01 1.4e-01 3.60 7.2 4.5e-13 0.26 0.04 0.13 FALSE
8 GTEx Cells EBV-transformed lymphocytes HACE1 0.40 0.15 lasso 8 0.22 1.1e-07 9.27 -10.9 1.9e-27 -0.43 0.76 0.14 FALSE
9 GTEx Cells Transformed fibroblasts HACE1 0.07 0.02 lasso 3 0.01 3.0e-02 3.38 -8.5 1.7e-17 -0.34 0.09 0.44 TRUE
10 GTEx Esophagus Mucosa HACE1 0.17 0.03 lasso 6 0.04 9.6e-04 -2.40 -7.4 1.8e-13 -0.28 0.65 0.07 TRUE
11 GTEx Lung HACE1 0.09 0.00 lasso 4 0.00 6.2e-01 -0.99 -15.3 7.0e-53 -0.56 0.06 0.22 TRUE
12 GTEx Thyroid HACE1 0.08 0.06 lasso 4 0.04 8.9e-04 9.27 -10.0 1.2e-23 -0.35 0.26 0.04 FALSE
13 ROSMAP Brain Pre-frontal Cortex HACE1 0.16 0.16 lasso 5 0.16 1.4e-20 9.27 -9.0 2.8e-19 -0.36 1.00 0.00 FALSE
14 ROSMAP Brain Pre-frontal Cortex BVES 0.08 0.00 enet 26 0.05 7.3e-07 0.47 5.2 2.4e-07 0.26 0.15 0.10 TRUE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma HACE1 0.05 0.01 blup 72 0.02 1.6e-03 6.81 -6.9 4.2e-12 -0.25 0.50 0.31 TRUE
16 The Cancer Genome Atlas Brain Lower Grade Glioma HACE1 0.08 0.04 blup 72 0.05 1.1e-06 3.38 -5.9 3.2e-09 -0.26 0.62 0.30 FALSE
17 The Cancer Genome Atlas Pancreatic Adenocarcinoma HACE1 0.17 0.03 enet 21 0.11 3.2e-05 -2.40 -7.3 4.0e-13 -0.17 0.09 0.20 TRUE
18 The Cancer Genome Atlas Prostate Adenocarcinoma HACE1 0.04 0.03 lasso 7 0.03 3.8e-04 6.82 -6.3 2.7e-10 -0.26 0.43 0.04 FALSE
19 The Cancer Genome Atlas Thyroid Carcinoma HACE1 0.09 0.03 enet 18 0.06 1.9e-06 6.84 -7.9 2.2e-15 -0.28 0.52 0.35 TRUE