TWAS hub - POPDC3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.057	0.023	0.0037	0.030	0.014	0.016	0.022	0.017	0.00012	0.00750	3.8e-03	0.001	0.00340
2	TCGA	Colon Adenocarcinoma	0.055	0.033	0.0039	0.041	0.034	0.029	NA	0.033	0.00200	0.00460	8.3e-03	NA	0.00530
3	TCGA	Pancreatic Adenocarcinoma	0.211	0.096	0.0010	0.042	0.104	0.100	NA	0.069	0.00760	0.00004	5.5e-05	NA	0.00079

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Age when periods started (menarche)	12.3	29.5	85.9	-9.3	1.0	-1.2
Mineral and other dietary supplements	4.4	5.9	10.0	-3.2	2.5	1.2
Heart disease (mother)	3.4	4.1	9.9	3.1	-0.9	-1.3
Chronotype (morning person)	3.1	7.1	11.0	3.3	-2.4	-2.2
Supplements: Glucosamine	3.1	4.0	9.4	1.6	-3.1	-0.0
Lung cancer (father)	3.1	3.6	5.8	-2.4	2.3	0.3
Ovarian Cancer	3.0	4.0	7.7	-2.0	-0.4	2.8
Impedance of arm (right)	2.9	13.7	32.7	-5.7	2.9	0.2
Standing height	2.9	28.6	85.2	-9.2	0.8	-0.4
Supplements: Fish oil (including cod liver oil)	2.9	3.7	6.2	2.5	-2.2	-0.5
Reaction Time	2.8	5.3	10.3	-3.2	2.3	0.0
Bilateral oophorectomy (both ovaries removed)	2.8	3.2	8.6	2.9	1.1	0.1
Alzheimer’s Disease (in father)	2.7	3.0	4.6	-1.9	2.1	0.9
Height	2.7	51.9	146.4	-12.1	2.8	-1.1
Forced expiratory volume in 1-second (FEV1)	2.7	9.0	25.5	-5.0	1.2	-0.0
Forced expiratory volume in 1-second (FEV1), predicted	2.7	5.5	15.8	-4.0	0.1	-0.9
Primary Biliary Cirrhosis	2.5	3.6	4.6	2.1	1.8	-1.7
Number of children fathered	2.5	2.8	8.0	2.8	0.1	-0.7
Mean time to correctly identify matches	2.5	4.7	7.3	-2.6	2.7	0.4
Forced vital capacity (FVC), Best measure	2.4	8.6	24.4	-4.9	1.0	0.7
Hearing aid user	2.4	2.7	4.2	-2.1	2.0	0.2
Impedance of arm (left)	2.3	10.4	24.7	-5.0	2.6	-0.0
Loud music exposure frequency	2.3	2.5	3.8	-1.8	-0.7	2.0
Forced vital capacity (FVC)	2.2	8.7	24.7	-5.0	1.0	0.6
Age at First Birth	2.1	3.1	3.8	-1.8	2.0	1.5
Relative age voice broke	2.1	3.2	8.6	-2.9	0.8	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	2.1	6.6	19.5	-4.4	0.4	0.1
Reason for reducing amount of alcohol drunk: Health precaution	2.1	2.5	4.0	-1.8	2.0	0.6
Medication: Simvastatin	2.0	3.0	8.2	0.7	-0.3	2.9
Depression (self-reported)	2.0	2.3	5.4	1.2	-0.4	-2.3
Medication: Ibuprofen	2.0	2.4	4.6	2.2	-1.1	-1.1
Long-standing illness, disability or infirmity	2.0	3.0	8.7	2.9	0.5	-0.3
Ever highly irritable/argumentative for 2 days	1.9	2.3	4.4	1.6	-2.1	0.2
Tinnitus: Yes, now most or all of the time	1.9	2.2	4.8	1.2	2.2	0.7
Ever had prostate specific antigen (PSA) test	1.9	2.2	3.0	1.7	0.9	1.6
Guilty feelings	1.8	2.6	6.8	2.6	-0.7	-0.8
Alzheimer’s Disease (including proxy)	1.7	2.4	4.5	-1.6	2.1	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.7	2.6	5.3	0.4	-2.3	-1.5
Pulse wave reflection index	1.7	2.1	3.6	1.6	-1.9	0.2
Commuting to job workplace: Car/motor vehicle	1.7	1.9	4.2	0.5	1.2	-2.0
Diabetes diagnosed by doctor	1.7	2.8	5.1	1.6	-0.8	2.3
Wears glasses or contact lenses	1.7	1.9	3.5	1.9	-1.5	-0.3
Impedance of whole body	1.7	8.5	21.1	-4.6	2.1	-0.2
Type 2 Diabetes (T2D) (2018)	1.6	3.1	8.2	1.0	0.0	2.9
Average weekly spirits intake	1.6	2.0	3.8	-1.3	2.0	0.7
Diabetes (self-reported)	1.6	2.4	4.8	1.5	-0.3	2.2
Medication: Ramipril	1.6	2.0	5.7	2.4	-0.3	-0.6
Health satisfaction	1.6	2.0	4.5	-2.1	0.2	1.2
Deep venous thrombosis (DVT) (self-reported)	1.6	2.1	5.2	0.1	2.3	-1.1
Medication: Co-codamol	1.5	1.8	2.9	1.7	0.9	-1.3
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	4.4	2.1	-0.6	-1.1
Medication: Omeprazole	1.5	1.8	5.1	2.3	0.3	0.5
Pulse rate, automated reading	1.5	4.9	7.8	-1.6	2.1	-2.8
Medication: Omeprazole (e.g. Zanprol)	1.5	1.9	5.5	2.3	-0.1	0.2
Bipolar Disorder (2011)	1.4	1.3	2.2	0.1	-1.5	-1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.7	2.6	1.6	-0.2	-1.5
Chest pain or discomfort	1.4	2.0	3.7	-1.9	0.7	1.3
Back pain experienced in last month	1.4	2.1	2.2	1.4	-1.5	-1.4
Ever smoked	1.4	2.5	7.3	-2.7	-0.4	-0.2
Heart disease (siblings)	1.4	1.7	3.8	1.2	-0.0	-2.0
Neuroticism (2016)	1.3	1.9	3.8	1.0	-2.0	1.0
Townsend deprivation index at recruitment	1.3	1.8	3.5	-1.9	0.5	1.3
Chronic bronchitis/emphysema (father)	1.3	1.5	2.1	-1.5	1.3	-0.8
Medication for cholesterol, blood pressure or diabetes	1.3	2.1	3.4	-1.8	-0.2	-1.7
Wheeze or whistling in the chest in last year	1.3	2.3	3.0	-1.6	1.7	1.1
Pulse wave peak to peak time	1.3	1.5	4.2	-0.3	2.0	0.5
Shortness of breath walking on level ground	1.3	1.6	3.2	-1.2	-0.1	1.8
Mother’s age at death	1.3	1.7	4.7	-0.4	2.2	0.4
Mean Putamen Volume	1.2	1.4	2.3	1.2	-1.5	0.5
Mouth/teeth dental problems	1.2	1.8	3.0	-0.6	1.4	1.7
Mouth/teeth dental problems: Dentures	1.2	2.1	5.2	0.9	-0.4	-2.3
Medication: Cholesterol lowering	1.2	1.9	4.0	1.3	0.2	2.0
Hair/balding pattern: Pattern 4	1.2	2.8	7.5	-2.7	-0.6	-0.8
Number of full brothers	1.2	1.5	2.2	0.9	1.5	-1.3
Medication for pain relief, constipation, heartburn	1.2	2.1	6.0	-2.4	0.3	0.4
Medication: Blood pressure	1.2	2.1	4.1	2.0	0.1	1.5
Commuting to job workplace: Walk	1.2	1.3	3.1	-0.9	-1.8	0.1
Alcohol drinker status: Never	1.2	1.4	2.6	1.6	1.3	-0.0
Number of operations (self-reported)	1.2	1.7	4.4	2.1	-0.8	-0.2
Ever depressed for a whole week	1.2	1.5	2.9	0.2	-1.7	1.3
Crohns Disease (2012)	1.1	1.7	3.3	1.4	-1.8	-0.2
Number of treatments/medications taken	1.1	1.9	4.4	2.1	0.2	1.2
Relative age of first facial hair	1.1	2.2	4.2	-2.0	-0.4	1.5
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	2.2	1.2	0.2	1.5
Vitamin and mineral supplements	1.1	1.4	2.5	-1.3	1.6	0.4
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	2.3	0.9	0.9	1.5
Medication: Atenolol	1.1	1.3	3.1	-0.4	0.9	1.8
Father’s age at death	1.1	1.5	2.3	-1.0	-1.1	1.5
Pulse wave Arterial Stiffness index	1.1	1.3	3.7	-0.3	-1.9	-0.4
Blood clot in the leg (DVT)	1.1	1.4	3.5	0.0	1.9	-0.8
Suffer from ‘nerves’	1.1	1.7	3.9	-0.6	-2.0	-0.9
Had major operations	1.1	1.3	3.5	1.9	-0.7	0.0
Miserableness	1.1	1.8	4.2	0.8	-2.1	-0.8
Medication: Metformin	1.0	1.4	2.7	1.2	-0.4	1.6
High blood pressure (mother)	1.0	1.4	2.6	1.6	-0.8	-1.0
Number of live births	1.0	1.4	3.2	1.8	-0.2	-1.0
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	2.4	-0.5	1.6	-0.8
Prospective memory result	1.0	1.2	2.8	0.7	0.6	-1.7
Chronic bronchitis/emphysema (mother)	1.0	1.1	2.1	0.0	1.4	1.2
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	2.5	-0.2	0.9	1.6
Smoking status: Current	1.0	1.6	4.4	-2.1	0.6	0.2
Basal cell carcinoma (self-reported)	1.0	1.2	2.9	-1.7	-0.8	0.2
Alcohol drinker status: Previous	1.0	1.2	3.0	1.7	-0.6	0.4
Major Depression (MDD)	0.9	1.1	2.4	1.0	0.3	1.6
Lung FEV1/FVC ratio	0.9	4.7	11.2	-3.4	-0.8	-1.4
Frequency of depressed mood in last 2 weeks	0.9	1.3	2.1	1.4	-1.2	0.5
Hearing difficulty/problems: Yes	0.9	1.3	3.6	-0.5	1.9	0.3
Current tobacco smoking	0.9	1.5	4.2	-2.1	0.6	-0.1
Average weekly fortified wine intake	0.9	1.1	2.9	-0.5	-0.2	-1.7
Maternal smoking around birth	0.9	1.3	2.7	-0.5	-0.9	-1.6
Hair/balding pattern: Pattern 2	0.9	1.2	1.9	-0.9	1.4	-0.9
Illnesses of siblings	0.9	1.3	1.5	-1.2	-1.1	1.1
High blood pressure (siblings)	0.9	1.3	4.0	2.0	-0.1	-0.2
Age at first live birth	0.9	1.6	3.4	-0.3	1.1	1.8
High cholesterol (Self-reported)	0.9	1.6	3.1	1.3	-0.1	1.8
Triglycerides	0.8	1.4	3.8	1.9	-0.3	-0.5
Blood White Count	0.8	6.3	8.3	-2.6	1.9	2.9
Heel T-Score	0.8	6.0	12.8	3.6	-2.2	0.5
Cardiovascular Disease	0.8	2.6	7.3	0.5	0.5	2.7
Systolic blood pressure, automated reading	0.8	2.2	4.9	-1.1	2.2	0.7
Severe depression (siblings)	0.8	0.9	1.0	-0.9	-0.8	1.0
Leg fat-free mass (left)	0.8	4.0	10.8	-3.3	-0.7	0.8
Fed-up feelings	0.8	1.4	3.4	1.8	-0.7	0.6
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	1.9	-0.6	-1.4	0.4
Multivitamins +/- minerals	0.8	1.0	2.3	0.7	-1.5	-0.4
Leg predicted mass (left)	0.8	4.2	11.7	-3.4	-0.7	0.7
Trunk fat mass	0.8	3.4	9.4	-3.1	0.6	0.7
Peak expiratory flow (PEF)	0.8	1.9	4.9	-2.2	0.9	-0.2
Comparative body size at age 10	0.8	2.1	3.7	1.9	-1.3	-1.0
Leg fat-free mass (right)	0.8	4.4	11.4	-3.4	-1.1	0.7
Loneliness, isolation	0.8	1.1	2.5	-0.6	-0.8	1.6
Qualifications: nursing, teaching	0.8	1.2	2.2	-0.5	-1.1	-1.5
Leg predicted mass (right)	0.8	4.3	11.3	-3.4	-1.1	0.7
Average weekly champagne plus white wine intake	0.8	1.1	2.7	0.6	-0.3	-1.7
Basal metabolic rate	0.8	4.2	12.0	-3.5	-0.4	0.5
Heart attack/myocardial infarction (self-reported)	0.8	1.0	2.8	1.7	-0.2	-0.4
Depression (Nagel 2018)	0.7	1.0	1.8	1.3	-0.9	0.6
Alzheimer’s Disease (in mother)	0.7	0.8	1.3	-0.6	1.1	-0.8
LDL Cholesterol	0.7	1.1	2.3	-1.0	-0.1	1.5
Lupus	0.7	1.1	1.6	1.0	-1.3	-0.7
Impedance of leg (right)	0.7	3.5	6.0	-2.5	1.9	-0.9
Trunk fat percentage	0.7	2.8	7.3	-2.7	0.7	0.6
Hand grip strength (right)	0.7	2.0	6.0	-2.5	0.1	-0.1
Hayfever, allergic rhinitis or eczema	0.7	1.5	2.7	-1.6	1.0	0.9
Sitting height	0.7	4.7	13.7	-3.7	-0.7	0.1
Impedance of leg (left)	0.7	3.5	7.9	-2.8	1.4	-0.8
Heart attack	0.7	1.0	2.9	1.7	-0.0	-0.0
Trunk fat-free mass	0.7	3.8	11.2	-3.4	-0.2	0.2
Trunk predicted mass	0.7	3.9	11.6	-3.4	-0.2	0.3
Exposure to tobacco smoke outside home	0.7	0.9	1.5	-1.2	1.0	0.5
Mouth/teeth dental problems: Loose teeth	0.7	0.9	1.3	1.1	-1.1	-0.5
Alcohol intake frequency.	0.7	1.5	2.9	1.7	0.1	-1.3
Smoking status: Previous	0.7	1.1	2.1	0.7	-1.5	0.8
Whole body fat-free mass	0.7	4.1	11.7	-3.4	-0.5	0.5
Mouth/teeth dental problems: Mouth ulcers	0.7	1.0	2.0	-1.0	-1.4	0.2
Illnesses of father: None of the above (group 1)	0.7	0.8	1.3	1.1	-0.4	-1.0
Commuting to job workplace: Cycle	0.7	0.9	1.9	1.4	-0.9	-0.2
Bipolar Disorder (2018)	0.6	1.0	1.8	0.8	-0.6	-1.4
HDL Cholesterol	0.6	0.9	2.5	0.6	0.1	1.6
Rheumatoid Arthritis	0.6	0.8	1.5	-0.8	0.6	1.2
Systolic Blood Pressure	0.6	3.2	5.3	-2.1	2.3	0.2
Taking other prescription medications	0.6	0.9	1.7	1.3	0.5	0.9
Alcohol usually taken with meals	0.6	1.0	1.9	1.4	1.0	-0.2
Qualifications: None of the above	0.6	1.2	2.5	1.6	-0.8	0.7
Time employed in main current job	0.6	0.7	1.3	0.3	1.1	-0.9
Pulse rate	0.6	1.0	2.0	-1.0	1.4	0.2
Length of working week for main job	0.6	0.6	1.0	-0.7	1.0	-0.7
Birth weight	0.6	1.3	3.0	-1.7	0.6	-0.7
Age at last live birth	0.6	0.8	1.5	-0.5	0.9	1.2
Leg pain on walking	0.6	0.8	1.9	0.6	-1.4	0.2
Medication: Aspirin	0.6	0.7	1.2	0.6	-0.8	1.1
Illnesses of siblings: Diabetes	0.6	0.8	1.9	0.4	1.4	-0.5
Whole body water mass	0.6	3.6	10.4	-3.2	-0.5	0.4
Commuting to job workplace: Public transport	0.6	0.7	1.9	-1.4	0.4	0.4
Irritability	0.6	0.9	2.0	-0.5	-1.4	0.7
Cholesterol lowering medication	0.6	0.9	2.0	0.6	-0.6	1.4
Fasting Glucose	0.5	0.6	1.3	-1.1	0.6	0.2
Blood Eosinophil Count	0.5	3.6	4.9	1.4	-1.9	2.2
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.7	1.3	0.1	-0.5
Medication for hormone replacement therapy	0.5	0.5	0.6	0.8	0.7	0.7
Diabetes (father)	0.5	0.7	1.5	1.2	-0.7	0.1
Qualifications: CSEs or equivalent	0.5	0.7	2.0	-0.1	1.4	0.2
Weight	0.5	2.5	7.1	-2.7	-0.0	0.7
Falls in the last year	0.5	0.6	1.4	1.2	-0.5	0.5
Illnesses of mother	0.5	0.6	1.3	-0.3	-0.6	1.1
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.2	-1.5	-0.5	-0.2
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.4	0.6	-1.2	-0.3
Angina (self-reported)	0.5	0.7	1.7	0.3	0.4	-1.3
Whole body fat mass	0.5	2.0	5.2	-2.3	0.5	0.8
Hypertension (Self-reported)	0.5	1.5	3.8	1.9	-0.1	0.8
Average weekly red wine intake	0.5	0.8	1.1	0.5	-1.0	1.0
Mood swings	0.5	0.9	2.7	-0.1	-1.6	-0.2
Eye problems/disorders: Cataract	0.5	0.6	1.5	0.2	-1.2	-0.5
Osteoporosis (self-reported)	0.5	0.6	1.3	0.4	1.1	0.5
Medication: Gliclazide	0.5	0.6	0.9	0.1	0.9	0.9
Arm fat-free mass (left)	0.5	2.5	7.0	-2.6	-0.5	0.4
Risk taking	0.5	0.7	1.1	-1.0	-1.1	0.2
Arm predicted mass (left)	0.5	2.4	6.5	-2.5	-0.8	0.4
Smoking Status	0.4	1.0	2.6	-1.6	-0.3	0.6
Allergy or Eczema	0.4	1.1	2.2	-0.4	0.9	1.5
Hand grip strength (left)	0.4	0.9	2.7	-1.6	-0.4	-0.0
Angina	0.4	0.5	1.4	0.3	0.1	-1.2
Diabetes (mother)	0.4	0.5	0.8	-0.9	0.3	0.7
High blood pressure	0.4	1.0	2.4	1.5	0.1	0.8
Stomach or abdominal pain in last month	0.4	0.5	0.6	-0.6	0.8	0.7
Past tobacco smoking	0.4	0.7	1.6	0.5	1.3	-0.5
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.4	0.3	-1.2	0.2
Body fat percentage	0.4	1.4	3.0	-1.7	0.8	0.8
Eye problems/disorders: None of the above	0.4	0.5	0.8	0.7	-0.9	0.4
Emphysema/chronic bronchitis	0.4	0.4	0.6	-0.8	0.6	-0.6
Medication: Allopurinol	0.4	0.5	0.9	0.9	0.3	-0.8
Number of full sisters	0.4	0.5	1.1	1.0	-0.1	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.1	0.0	1.0	-0.6
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.3	-0.3	0.0	1.1
Knee pain experienced in last month	0.4	0.6	0.8	0.7	0.7	0.9
Handedness (chirality/laterality): Left-handed	0.4	0.5	0.8	0.6	-0.6	-0.9
Medication for cholesterol	0.4	0.6	1.8	0.0	-0.0	-1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	0.9	-0.0	0.7	-0.9
Osteoarthritis (self-reported)	0.4	0.5	1.2	-1.1	0.1	-0.5
Medication: Aspirin	0.4	0.5	0.8	0.9	-0.3	0.8
Bipolar Disorder or Schizophrenia	0.3	0.8	2.3	-0.1	0.1	-1.5
Depressed Affect (Nagel 2018)	0.3	0.6	1.7	0.2	-1.3	0.5
Schizophrenia (2018)	0.3	0.6	0.9	-0.7	0.6	-0.9
Irritable Bowel Disease (IBD)	0.3	0.7	1.0	0.5	-1.0	-0.9
Coronary Artery Disease (CAD)	0.3	0.4	1.1	1.0	0.1	0.0
Schizophrenia (2014)	0.3	0.8	1.7	-1.3	0.5	-0.6
Type 2 Diabetes (T2D) (2012)	0.3	0.4	0.9	0.4	0.1	1.0
Respiratory disease	0.3	0.6	1.2	0.4	0.7	1.1
Sensitivity / hurt feelings	0.3	0.6	1.2	0.3	-0.6	-1.1
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.7	0.6	0.9	0.5
Pack years adult smoking proportion	0.3	0.5	1.3	-0.5	-0.1	-1.1
Medication: Levothyroxine sodium	0.3	0.5	1.5	0.0	0.2	-1.2
Number of incorrect matches in round	0.3	0.5	1.2	0.5	-0.0	-1.1
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	0.8	-0.3	0.9	0.8
Allergy	0.3	0.7	0.9	1.0	-0.8	-0.8
Pain all over the body in last month	0.3	0.3	0.6	0.5	0.8	0.2
Arm fat percentage (right)	0.3	1.4	1.5	-1.2	1.2	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.0	-0.2	0.7	1.0
Hair/balding pattern: Pattern 3	0.3	0.4	0.7	-0.7	0.8	-0.3
Happiness	0.3	0.3	0.6	-0.8	0.2	0.6
Noisy workplace	0.3	0.4	0.6	0.8	-0.2	-0.7
Arm fat mass (right)	0.3	1.1	2.7	-1.6	0.4	0.7
Breastfed as a baby	0.3	0.4	0.8	0.9	-0.2	-0.5
Tense / ‘highly strung’	0.3	0.5	0.7	-0.1	0.9	-0.8
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.7	0.6	0.2	0.8
Arm fat-free mass (right)	0.3	1.8	4.3	-2.1	-1.0	-0.1
Qualifications: College or University degree	0.3	0.8	1.5	-1.2	-0.6	-0.8
Arm predicted mass (right)	0.3	1.7	4.2	-2.1	-0.9	0.1
Supplements: Vitamin C	0.3	0.3	0.5	-0.4	-0.5	-0.7
Arm fat percentage (left)	0.3	1.0	1.1	-1.0	1.0	1.1
Ever had bowel cancer screening	0.3	0.4	1.1	1.0	0.2	-0.2
Medication: Lisinopril	0.3	0.4	1.0	0.3	-0.3	1.0
Medication: Atorvastatin	0.3	0.3	1.0	0.2	1.0	-0.2
Illnesses of father: High blood pressure	0.3	0.4	1.1	-0.1	-1.0	0.3
Age started oral contraceptive pill	0.3	0.4	1.2	-0.1	0.1	-1.1
Diastolic blood pressure, automated reading	0.3	1.0	2.3	-0.4	1.5	0.8
Vascular/heart problems diagnosed by doctor	0.3	0.8	2.2	-1.5	-0.2	-0.5
Supplements: Calcium	0.3	0.4	0.8	0.9	0.5	-0.2
Schizophrenia vs Biploar Disorder	0.2	0.3	0.4	-0.1	0.6	-0.6
Crohns Disease (2017)	0.2	0.3	0.4	0.5	-0.6	-0.6
Verbal and Numeric Reasoning (VNR)	0.2	0.5	0.6	-0.8	0.6	0.7
Breast Cancer	0.2	0.6	1.5	-1.2	-0.2	0.4
Body Mass Index (BMI) (2010)	0.2	0.3	0.4	-0.6	0.7	0.3
Blood Platelet Count	0.2	2.9	5.0	-2.2	1.5	1.1
Waist Hip Ratio (WHR)	0.2	0.8	2.2	-1.5	-0.1	0.5
Ever had hysterectomy (womb removed)	0.2	0.2	0.6	0.0	-0.2	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.8	-0.1	-0.2	-0.9
Body mass index (BMI)	0.2	0.9	2.1	1.4	-0.4	0.7
Had other major operations	0.2	0.3	0.7	0.2	-0.9	-0.0
Fluid intelligence score	0.2	0.5	0.8	-0.9	0.1	0.8
Hip circumference	0.2	1.0	1.6	-1.2	1.2	0.1
Alcohol intake versus 10 years previously	0.2	0.3	0.7	-0.8	-0.0	0.3
Asthma	0.2	0.4	0.6	0.7	0.4	0.8
Birth weight of first child	0.2	0.4	0.7	-0.9	-0.1	-0.7
Headache pain in last month	0.2	0.3	0.5	-0.3	-0.7	0.6
Glaucoma (self-reported)	0.2	0.2	0.4	-0.5	0.3	0.6
Gout (self-reported)	0.2	0.3	0.7	0.4	0.8	-0.0
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	0.7	0.8	0.5	-0.2
Medication: Amlodipine	0.2	0.3	0.6	0.8	0.1	0.6
Worry too long after embarrassment	0.2	0.3	0.7	-0.4	0.8	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.6	-0.3	-0.5	0.8
Overall health rating	0.2	0.4	1.2	-0.2	1.1	0.2
Friendships satisfaction	0.2	0.3	0.7	-0.1	0.4	0.8
Breast cancer (self-reported)	0.2	0.2	0.5	0.1	0.3	-0.7
Asthma (self-reported)	0.2	0.4	0.5	0.7	0.6	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	0.8	-0.9	0.5	0.1
Arm fat mass (left)	0.2	1.0	2.0	-1.4	0.3	0.9
Eye problems/disorders: Glaucoma	0.2	0.2	0.5	-0.7	0.3	0.0
Medication: Bendroflumethiazide	0.2	0.3	0.5	-0.7	0.5	0.1
Average weekly beer plus cider intake	0.2	0.3	0.6	-0.8	-0.3	-0.5
Unable to work because of sickness or disability	0.2	0.2	0.6	0.3	-0.8	0.1
Pack years of smoking	0.2	0.4	0.9	-0.4	0.0	-0.9
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.5	-0.3	-0.0	0.7
Neuroticism (Nagel 2018)	0.1	0.3	0.8	0.3	-0.9	0.2
Ulcerative Colitis (UC)	0.1	0.2	0.5	0.2	-0.3	-0.7
HbA1C	0.1	0.1	0.2	-0.5	0.1	0.2
Ulcerative Colitis	0.1	0.2	0.4	0.0	0.7	-0.4
Blood Red Count	0.1	0.8	1.4	1.2	0.9	0.4
BMI	0.1	0.6	0.9	0.9	-0.9	0.2
Hypothyroidism (self reported)	0.1	0.2	0.5	0.1	0.7	-0.2
Tanning	0.1	1.6	4.5	-0.1	-0.6	-2.1
Supplements: Zinc	0.1	0.1	0.3	0.3	-0.1	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.5	-0.7	0.3	0.1
Serious illness, injury or assault to yourself	0.1	0.1	0.2	0.3	-0.2	-0.5
Nervous feelings	0.1	0.2	0.2	-0.3	0.4	0.4
Hearing difficulty/problems with background noise	0.1	0.2	0.3	0.5	0.5	0.4
Had menopause	0.1	0.1	0.2	0.3	0.5	0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.5	-0.7	0.4	0.1
Financial difficulties in last 2 years	0.1	0.1	0.2	0.1	-0.3	-0.5
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.1	0.3	0.4	0.2
Neuroticism score	0.1	0.2	0.3	0.3	-0.6	-0.3
Worrier / anxious feelings	0.1	0.2	0.6	0.1	0.8	-0.0
Qualifications: A levels/AS levels or equivalent	0.1	0.3	0.4	-0.6	-0.3	0.6
Medication: Lansoprazole	0.1	0.2	0.2	0.3	0.5	0.4
Medication: Paracetamol	0.1	0.1	0.1	0.3	-0.3	0.3
Leg fat percentage (right)	0.1	0.3	0.4	0.6	0.5	0.6
Neck or shoulder pain in last month	0.1	0.1	0.1	0.3	0.4	-0.1
Leg fat mass (right)	0.1	0.4	0.8	-0.6	0.2	0.9
Comparative height size at age 10	0.1	0.6	1.0	-1.0	0.8	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.1	0.4	0.2	-0.2
Number of self-reported non-cancer illnesses	0.1	0.2	0.4	0.4	-0.1	0.7
Ever taken oral contraceptive pill	0.1	0.1	0.4	-0.2	-0.6	0.0
Financial situation satisfaction	0.1	0.1	0.3	-0.0	0.5	0.1
Medication: Blood pressure	0.1	0.2	0.4	0.6	-0.3	-0.1
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.3	0.2	-0.5	-0.5
Medication: Paracetamol	0.1	0.1	0.3	0.6	-0.1	0.0
Leg fat percentage (left)	0.1	0.2	0.4	0.3	0.3	0.6
Fractured/broken bones in last 5 years	0.1	0.2	0.3	-0.6	0.5	-0.2
Myopia	0.1	0.1	0.3	-0.2	0.2	-0.5
Pain experienced in last month	0.1	0.2	0.6	-0.8	0.1	-0.3
Leg fat mass (left)	0.1	0.5	0.8	-0.8	0.0	0.9
Worry (Nagel 2018)	0.0	0.1	0.2	0.0	-0.0	0.4
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0
Lung FVC	0.0	0.2	0.3	0.4	0.5	-0.3
Neuroticism	0.0	0.1	0.1	0.1	-0.3	0.3
Hair Pigment	0.0	1.2	1.8	0.8	-1.0	-1.3
Waist circumference	0.0	0.2	0.4	-0.6	0.1	0.4
Exposure to tobacco smoke at home	0.0	0.0	0.0	0.0	0.1	0.2
Migraine (self-reported)	0.0	0.0	0.1	-0.2	-0.1	-0.3
Medication: Seretide 50 evohaler	0.0	0.0	0.1	-0.1	0.2	0.3
Family relationship satisfaction	0.0	0.0	0.1	-0.3	0.0	0.2
Illnesses of father: Heart disease	0.0	0.0	0.0	0.1	-0.2	0.1

Hub : Genes

POPDC3

Models

Trait associations