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chr6:111,121,188-112,823,511

Best TWAS P=3.12e-08 · Best GWAS P=4.38e-08 conditioned to 0.000965

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TRAF3IP2-AS1 0.57 0.29 lasso 8 0.44 4.1e-58 -3.9 5.2 1.8e-07 0.25 0.77 0.15 FALSE
2 GTEx Adipose Subcutaneous C6orf3 0.64 0.04 lasso 18 0.38 1.6e-32 -3.9 5.1 2.7e-07 0.42 0.47 0.48 FALSE
3 GTEx Artery Aorta C6orf3 0.48 0.11 lasso 6 0.37 2.4e-21 -3.9 5.5 4.4e-08 0.34 0.77 0.15 FALSE
4 GTEx Artery Tibial C6orf3 0.61 0.16 lasso 11 0.37 5.8e-30 -3.9 5.1 3.0e-07 0.30 0.76 0.16 FALSE
5 GTEx Brain Cerebellar Hemisphere C6orf3 0.50 0.09 lasso 4 0.27 1.1e-07 4.4 5.4 5.9e-08 0.43 0.10 0.38 FALSE
6 GTEx Brain Cerebellum C6orf3 0.76 0.10 lasso 19 0.45 7.0e-15 4.4 5.4 5.8e-08 0.33 0.20 0.28 FALSE
7 GTEx Brain Cortex C6orf3 0.72 0.26 lasso 13 0.48 5.6e-15 4.4 5.5 4.6e-08 0.42 0.18 0.48 FALSE
8 GTEx Colon Transverse C6orf3 0.37 0.08 lasso 4 0.24 1.6e-11 4.4 5.3 1.0e-07 0.29 0.38 0.47 FALSE
9 GTEx Esophagus Muscularis C6orf3 0.50 0.11 lasso 7 0.37 9.4e-24 -3.9 5.5 4.4e-08 0.28 0.76 0.16 FALSE
10 GTEx Lung C6orf3 0.50 0.09 enet 29 0.29 9.5e-23 -3.9 5.3 1.0e-07 0.28 0.52 0.42 FALSE
11 GTEx Nerve Tibial C6orf3 0.69 0.25 lasso 15 0.41 5.9e-31 -3.9 5.4 7.9e-08 0.22 0.77 0.15 FALSE
12 ROSMAP Brain Pre-frontal Cortex C6orf3 0.73 0.36 lasso 11 0.64 8.7e-108 -3.9 5.5 3.1e-08 0.33 0.77 0.15 TRUE
13 The Cancer Genome Atlas Breast Invasive Carcinoma LAMA4 0.02 0.01 blup 36 0.01 1.9e-03 5.0 5.3 1.2e-07 0.11 0.00 0.86 TRUE
14 The Cancer Genome Atlas Brain Lower Grade Glioma TRAF3IP2 0.07 0.05 lasso 3 0.04 7.4e-06 5.0 -5.1 2.7e-07 -0.85 0.01 0.99 FALSE