Best TWAS P=1.04e-11 · Best GWAS P=1.04e-20 conditioned to 9.62e-23
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Spleen | ABRACL | 0.40 | 0.13 | lasso | 8 | 0.13 | 0.0003 | 1.9 | -5.3 | 1.2e-07 | -0.04 | 0.03 | 0.81 | FALSE |
2 | NTR | Blood | REPS1 | 0.02 | 0.01 | lasso | 7 | 0.01 | 0.0016 | 3.6 | -5.9 | 3.3e-09 | -0.04 | 0.03 | 0.96 | FALSE |
3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | REPS1 | 0.03 | 0.02 | blup | 77 | 0.01 | 0.0124 | -6.9 | -6.8 | 1.0e-11 | -0.07 | 0.02 | 0.95 | TRUE |