Best TWAS P=2.4e-12 · Best GWAS P=2.91e-25 conditioned to 2e-18
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RPS6KA2 | 0.08 | 0.02 | lasso | 4 | 0.02 | 4.1e-03 | 7.2 | -7.0 | 2.4e-12 | 0.09 | 0.12 | 0.04 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | SDIM1 | 0.08 | 0.03 | enet | 15 | 0.04 | 1.9e-05 | -7.5 | 6.5 | 6.2e-11 | -0.37 | 0.75 | 0.18 | TRUE |