Best TWAS P=1.67e-133 · Best GWAS P=8.17e-164 conditioned to 2.47e-36
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | HIBADH | 0.14 | 0.07 | enet | 26 | 0.13 | 9.4e-16 | 1.7 | 5.3 | 1.0e-07 | 0.15 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Artery Aorta | JAZF1 | 0.17 | 0.00 | enet | 32 | 0.05 | 5.8e-04 | 13.8 | -6.3 | 2.2e-10 | -0.08 | 0.16 | 0.03 | FALSE |
| 3 | The Cancer Genome Atlas | Esophageal Carcinoma | EVX1 | 0.16 | 0.02 | blup | 50 | 0.12 | 1.4e-04 | -4.7 | 5.8 | 6.0e-09 | -0.06 | 0.02 | 0.05 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HIBADH | 0.09 | 0.01 | enet | 8 | 0.05 | 3.2e-06 | -0.8 | 5.2 | 2.2e-07 | 0.12 | 0.24 | 0.13 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | JAZF1 | 0.12 | 0.09 | lasso | 4 | 0.09 | 2.1e-09 | 24.3 | 24.6 | 1.7e-133 | 0.78 | 0.91 | 0.09 | TRUE |