Best TWAS P=4.67e-09 · Best GWAS P=5.54e-18 conditioned to 1.56e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | SLC25A40 | 0.03 | 0.00 | blup | 418 | 0.00 | 7.8e-02 | 6.4 | -5.5 | 4.7e-08 | -0.52 | 0.02 | 0.79 | FALSE |
| 2 | YFS | Blood | ABCB1 | 0.03 | 0.01 | enet | 16 | 0.02 | 5.3e-07 | 3.2 | -5.9 | 4.7e-09 | -0.61 | 0.06 | 0.94 | TRUE |
| 3 | YFS | Blood | CROT | 0.02 | 0.02 | enet | 12 | 0.03 | 7.1e-09 | 6.4 | 5.8 | 8.4e-09 | 0.44 | 0.95 | 0.03 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ABCB4 | 0.12 | 0.03 | enet | 16 | 0.08 | 6.4e-09 | 6.4 | -5.5 | 4.0e-08 | -0.47 | 0.02 | 0.98 | FALSE |