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chr7:90,624,416-93,476,736

Best TWAS P=8.03e-258 · Best GWAS P=1.03e-249 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CDK6	0.12	0.10	lasso	2	0.10	1.9e-12	32.89	32.9	1.2e-237	0.90	0.07	0.93	TRUE
2	CommonMind	Brain Pre-frontal Cortex	CYP51A1	0.05	0.08	lasso	5	0.06	2.4e-08	8.67	-8.2	3.7e-16	-0.24	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	KRIT1	0.04	0.01	blup	318	0.02	1.2e-03	8.37	-10.6	4.3e-26	-0.28	0.60	0.02	TRUE
4	GTEx	Adipose Subcutaneous	GATAD1	0.21	0.14	enet	10	0.16	3.4e-13	17.97	-15.4	9.3e-54	-0.42	1.00	0.00	FALSE
5	GTEx	Adipose Visceral Omentum	GATAD1	0.12	0.08	lasso	5	0.06	7.5e-04	17.97	-18.9	7.1e-80	-0.53	0.68	0.21	TRUE
6	GTEx	Adrenal Gland	GATAD1	0.40	0.22	lasso	7	0.25	2.0e-09	17.97	-19.6	9.4e-86	-0.52	0.68	0.07	FALSE
7	GTEx	Artery Aorta	KRIT1	0.15	0.00	enet	24	0.03	1.3e-02	1.50	-16.1	2.7e-58	-0.35	0.12	0.09	FALSE
8	GTEx	Artery Aorta	GATAD1	0.09	0.08	enet	4	0.07	7.4e-05	17.97	-17.9	6.0e-72	-0.48	0.54	0.03	FALSE
9	GTEx	Artery Aorta	AC000120.7	0.06	0.09	lasso	4	0.08	3.4e-05	8.31	-8.3	8.8e-17	-0.22	0.93	0.00	FALSE
10	GTEx	Artery Coronary	GATAD1	0.12	0.15	lasso	3	0.12	8.0e-05	17.82	-18.4	6.8e-76	-0.48	0.21	0.12	FALSE
11	GTEx	Artery Coronary	AC000120.7	0.07	0.04	lasso	4	0.02	6.8e-02	8.05	-8.9	6.8e-19	-0.24	0.20	0.04	FALSE
12	GTEx	Artery Tibial	GATAD1	0.14	0.04	enet	17	0.04	4.1e-04	17.97	-17.6	4.0e-69	-0.45	0.72	0.09	FALSE
13	GTEx	Artery Tibial	AC000120.7	0.08	0.06	lasso	4	0.06	3.2e-05	7.45	-10.4	2.0e-25	-0.29	0.96	0.00	TRUE
14	GTEx	Artery Tibial	AC007566.10	0.13	0.04	lasso	5	0.00	3.1e-01	10.33	-13.2	1.4e-39	-0.21	0.08	0.03	FALSE
15	GTEx	Brain Caudate basal ganglia	GATAD1	0.21	0.09	lasso	4	0.08	2.3e-03	13.54	-20.0	2.7e-89	-0.48	0.08	0.23	FALSE
16	GTEx	Brain Cortex	AC000120.7	0.12	0.08	enet	16	0.07	7.0e-03	8.67	-13.7	7.2e-43	-0.45	0.14	0.05	FALSE
17	GTEx	Breast Mammary Tissue (Female)	AC007566.10	0.04	-0.01	lasso	2	0.01	2.0e-01	1.06	-14.5	1.3e-47	-0.35	0.03	0.17	FALSE
18	GTEx	Cells Transformed fibroblasts	GATAD1	0.23	0.20	lasso	4	0.22	1.4e-16	17.97	-23.4	5.0e-121	-0.60	1.00	0.00	FALSE
19	GTEx	Cells Transformed fibroblasts	AC000120.7	0.04	0.05	lasso	4	0.04	5.2e-04	7.97	-8.4	4.7e-17	-0.23	0.82	0.01	FALSE
20	GTEx	Colon Sigmoid	AC000120.7	0.09	0.08	lasso	3	0.07	2.2e-03	7.07	-5.3	1.1e-07	-0.17	0.32	0.04	FALSE
21	GTEx	Colon Transverse	GATAD1	0.13	0.00	enet	16	0.05	3.0e-03	17.97	-19.2	1.6e-82	-0.44	0.23	0.06	FALSE
22	GTEx	Colon Transverse	AC000120.7	0.09	0.04	lasso	5	0.01	9.4e-02	8.30	-8.2	2.7e-16	-0.22	0.23	0.04	FALSE
23	GTEx	Esophagus Mucosa	AKAP9	0.04	0.03	lasso	15	0.02	2.7e-02	8.28	8.1	4.4e-16	0.22	0.76	0.03	FALSE
24	GTEx	Esophagus Mucosa	GATAD1	0.16	0.05	enet	16	0.08	7.3e-06	17.97	-19.1	2.6e-81	-0.51	0.82	0.05	FALSE
25	GTEx	Esophagus Muscularis	GATAD1	0.18	0.10	enet	33	0.13	1.6e-08	17.97	-16.7	1.5e-62	-0.40	0.98	0.00	FALSE
26	GTEx	Esophagus Muscularis	FAM133B	0.07	0.01	enet	2	0.01	1.2e-01	-22.88	-22.6	5.1e-113	-0.56	0.05	0.51	FALSE
27	GTEx	Heart Atrial Appendage	AKAP9	0.06	0.01	enet	11	0.02	4.5e-02	7.59	-8.0	8.7e-16	-0.22	0.31	0.04	FALSE
28	GTEx	Lung	GATAD1	0.15	0.12	lasso	2	0.11	1.1e-08	17.97	-18.1	3.4e-73	-0.48	0.99	0.00	FALSE
29	GTEx	Lung	AC000120.7	0.04	0.03	lasso	3	0.01	4.8e-02	8.28	-8.4	5.3e-17	-0.22	0.46	0.02	FALSE
30	GTEx	Muscle Skeletal	CYP51A1	0.10	0.18	enet	21	0.17	5.0e-16	8.39	-9.2	3.9e-20	-0.24	1.00	0.00	TRUE
31	GTEx	Muscle Skeletal	PEX1	0.06	0.03	lasso	5	0.02	2.7e-03	14.41	15.3	1.3e-52	0.34	0.49	0.20	FALSE
32	GTEx	Muscle Skeletal	GATAD1	0.05	0.00	enet	13	0.01	2.4e-02	8.31	-18.8	7.3e-79	-0.45	0.48	0.02	FALSE
33	GTEx	Nerve Tibial	ANKIB1	0.04	0.04	enet	2	0.02	8.5e-03	8.71	-9.2	3.3e-20	-0.24	0.43	0.03	FALSE
34	GTEx	Nerve Tibial	AKAP9	0.03	0.05	lasso	2	0.03	2.7e-03	8.43	8.4	3.5e-17	0.23	0.45	0.04	FALSE
35	GTEx	Nerve Tibial	GATAD1	0.30	0.19	lasso	5	0.23	1.8e-16	17.97	-15.5	1.7e-54	-0.41	1.00	0.00	FALSE
36	GTEx	Pancreas	GATAD1	0.12	0.13	lasso	2	0.14	2.0e-06	17.97	-15.9	8.1e-57	-0.46	0.26	0.20	FALSE
37	GTEx	Pancreas	AC000120.7	0.05	0.03	enet	12	0.02	4.4e-02	7.22	-7.3	2.2e-13	-0.23	0.29	0.04	FALSE
38	GTEx	Pituitary	KRIT1	0.21	-0.01	enet	14	0.20	1.1e-05	1.55	-9.8	8.1e-23	-0.15	0.27	0.10	FALSE
39	GTEx	Prostate	AC000120.7	0.13	0.09	lasso	3	0.09	2.8e-03	8.37	-8.3	8.4e-17	-0.23	0.13	0.08	FALSE
40	GTEx	Skin Not Sun Exposed Suprapubic	GATAD1	0.22	0.27	lasso	4	0.26	1.1e-14	17.97	-18.5	1.4e-76	-0.48	1.00	0.00	FALSE
41	GTEx	Skin Not Sun Exposed Suprapubic	SAMD9L	0.20	0.11	enet	19	0.06	3.6e-04	2.36	-9.9	3.9e-23	0.00	0.36	0.03	TRUE
42	GTEx	Skin Not Sun Exposed Suprapubic	AC000120.7	0.09	0.02	enet	38	0.07	8.3e-05	7.31	-6.0	2.7e-09	-0.04	0.24	0.03	TRUE
43	GTEx	Skin Sun Exposed Lower leg	PEX1	0.18	0.06	enet	41	0.03	1.5e-03	-18.07	-17.7	2.2e-70	-0.49	0.21	0.14	FALSE
44	GTEx	Skin Sun Exposed Lower leg	GATAD1	0.30	0.10	enet	14	0.16	7.0e-13	17.97	-19.2	2.4e-82	-0.45	1.00	0.00	FALSE
45	GTEx	Skin Sun Exposed Lower leg	AC000120.7	0.06	0.00	enet	24	0.00	7.9e-01	2.74	-8.5	2.7e-17	-0.19	0.15	0.03	FALSE
46	GTEx	Spleen	PEX1	0.18	0.00	enet	38	0.05	2.4e-02	9.13	-14.0	9.8e-45	-0.29	0.08	0.06	FALSE
47	GTEx	Spleen	AC000120.7	0.10	0.07	lasso	5	0.04	3.9e-02	8.28	-9.4	5.4e-21	-0.22	0.15	0.06	FALSE
48	GTEx	Stomach	GATAD1	0.30	0.13	lasso	5	0.15	8.6e-08	17.97	-19.1	1.6e-81	-0.53	0.98	0.00	FALSE
49	GTEx	Testis	CDK6	0.10	0.10	lasso	3	0.09	8.0e-05	32.58	-34.3	8.0e-258	-0.84	0.06	0.91	TRUE
50	GTEx	Thyroid	GATAD1	0.18	0.06	lasso	4	0.06	3.3e-05	17.97	-17.8	9.1e-71	-0.49	0.96	0.02	FALSE
51	GTEx	Thyroid	AC000120.7	0.04	0.01	lasso	6	0.02	2.2e-02	6.98	-5.2	2.0e-07	-0.18	0.33	0.03	FALSE
52	GTEx	Whole Blood	AKAP9	0.13	0.00	enet	15	0.01	5.1e-02	-8.09	-7.0	3.4e-12	-0.10	0.45	0.02	FALSE
53	METSIM	Adipose	GATAD1	0.10	0.05	lasso	7	0.06	9.4e-10	8.31	-16.0	2.1e-57	-0.47	0.97	0.03	FALSE
54	ROSMAP	Brain Pre-frontal Cortex	ANKIB1	0.03	0.03	enet	8	0.03	2.6e-04	9.27	-9.7	3.7e-22	-0.22	0.70	0.01	FALSE
55	ROSMAP	Brain Pre-frontal Cortex	CYP51A1	0.04	0.02	blup	287	0.03	4.7e-05	8.00	-5.7	1.6e-08	-0.20	0.95	0.00	FALSE
56	ROSMAP	Brain Pre-frontal Cortex	KRIT1	0.04	0.03	bslmm	311	0.01	9.0e-03	9.10	17.2	1.1e-66	0.44	0.77	0.02	FALSE
57	ROSMAP	Brain Pre-frontal Cortex	AKAP9	0.04	0.00	blup	344	0.01	8.6e-03	1.55	-6.0	1.6e-09	-0.19	0.32	0.02	FALSE
58	ROSMAP	Brain Pre-frontal Cortex	MTERF	0.04	0.00	blup	375	0.02	7.5e-04	0.93	7.5	9.2e-14	0.17	0.08	0.44	FALSE
59	ROSMAP	Brain Pre-frontal Cortex	GATAD1	0.17	0.15	lasso	4	0.16	6.0e-20	18.13	-19.1	5.0e-81	-0.49	1.00	0.00	FALSE
60	ROSMAP	Brain Pre-frontal Cortex	SAMD9L	0.14	0.16	enet	8	0.16	9.0e-20	3.22	-5.6	2.2e-08	0.04	1.00	0.00	FALSE
61	YFS	Blood	CYP51A1	0.03	0.06	blup	288	0.05	1.2e-16	8.70	-12.1	6.6e-34	-0.30	1.00	0.00	FALSE
62	YFS	Blood	GATAD1	0.01	0.01	blup	297	0.01	5.1e-04	17.97	-22.2	1.7e-109	-0.59	0.74	0.09	FALSE
63	The Cancer Genome Atlas	Breast Invasive Carcinoma	CYP51A1	0.01	0.02	blup	51	0.02	2.0e-04	8.28	-9.0	3.3e-19	-0.23	0.14	0.78	FALSE
64	The Cancer Genome Atlas	Breast Invasive Carcinoma	GATAD1	0.06	0.04	lasso	6	0.04	2.2e-09	17.76	-16.9	2.2e-64	-0.35	0.86	0.14	FALSE
65	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CYP51A1	0.07	0.04	lasso	2	0.04	4.3e-05	9.27	-9.1	1.0e-19	-0.23	0.01	0.99	FALSE
66	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CYP51A1	0.04	0.05	blup	51	0.05	9.4e-07	8.40	-8.7	3.6e-18	-0.23	0.35	0.65	FALSE
67	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GATAD1	0.04	0.04	lasso	2	0.03	2.8e-04	17.76	-17.1	7.5e-66	-0.41	0.10	0.42	FALSE
68	The Cancer Genome Atlas	Brain Lower Grade Glioma	CYP51A1	0.01	0.01	blup	51	0.01	1.2e-02	8.28	-8.8	2.1e-18	-0.23	0.05	0.49	FALSE
69	The Cancer Genome Atlas	Lung Adenocarcinoma	CYP51A1	0.03	0.03	enet	12	0.03	1.2e-04	9.25	-9.4	4.5e-21	-0.24	0.01	0.98	FALSE
70	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LOC401387	0.04	0.00	lasso	1	0.00	1.6e-01	8.42	8.4	3.7e-17	0.24	0.05	0.26	FALSE
71	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C7orf64	0.06	0.02	blup	36	0.02	6.0e-02	14.51	12.2	4.5e-34	0.25	0.02	0.48	FALSE
72	The Cancer Genome Atlas	Prostate Adenocarcinoma	MTERF	0.03	0.03	blup	47	0.04	1.2e-04	8.13	8.4	5.1e-17	0.21	0.03	0.95	FALSE