Best TWAS P=4.59e-35 · Best GWAS P=2.11e-26 conditioned to 0.138
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | CREB3L2 | 0.19 | 0.05 | enet | 36 | 0.07 | 6.5e-05 | 3.9 | -5.2 | 1.7e-07 | 0.26 | 0.10 | 0.16 | FALSE |
| 2 | GTEx | Muscle Skeletal | CREB3L2 | 0.13 | 0.08 | enet | 12 | 0.10 | 3.0e-10 | -7.1 | 5.3 | 9.6e-08 | -0.37 | 1.00 | 0.00 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | CREB3L2 | 0.05 | 0.00 | enet | 10 | 0.01 | 9.0e-03 | -6.7 | -9.9 | 5.7e-23 | 0.55 | 0.05 | 0.71 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CREB3L2 | 0.01 | 0.00 | blup | 94 | 0.01 | 1.0e-02 | -9.7 | -12.4 | 4.6e-35 | 0.78 | 0.02 | 0.72 | TRUE |