Best TWAS P=8.72e-11 · Best GWAS P=1.16e-10 conditioned to 0.00184
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | NMT2 | 0.28 | 0.07 | lasso | 7 | 0.08 | 5.6e-07 | 6.4 | -5.8 | 7.5e-09 | -0.50 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Nerve Tibial | NMT2 | 0.23 | 0.14 | enet | 22 | 0.14 | 4.4e-10 | 5.5 | -5.6 | 2.0e-08 | -0.43 | 0.13 | 0.87 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C10orf111 | 0.26 | 0.09 | lasso | 6 | 0.12 | 4.6e-14 | 5.1 | -5.9 | 3.4e-09 | -0.72 | 0.03 | 0.97 | FALSE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | NMT2 | 0.12 | 0.13 | lasso | 4 | 0.07 | 6.7e-04 | 6.4 | -6.5 | 8.7e-11 | -0.61 | 0.00 | 0.98 | TRUE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | NMT2 | 0.09 | 0.05 | lasso | 3 | 0.04 | 5.2e-05 | 5.5 | -5.4 | 7.3e-08 | -0.35 | 0.06 | 0.81 | FALSE |