Best TWAS P=4.7e-08 · Best GWAS P=6.75e-28 conditioned to 9.28e-24
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | ASAH2B | 0.53 | 0.32 | enet | 44 | 0.27 | 1.5e-09 | -2.7 | -5.2 | 1.9e-07 | 0.13 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Brain Cortex | ASAH2B | 0.31 | 0.18 | lasso | 4 | 0.31 | 3.3e-09 | 5.9 | -5.5 | 4.7e-08 | 0.23 | 0.66 | 0.02 | TRUE |
| 3 | GTEx | Liver | TIMM23 | 0.19 | 0.02 | lasso | 7 | 0.04 | 2.2e-02 | -3.4 | -5.3 | 9.4e-08 | -0.02 | 0.03 | 0.07 | TRUE |