Best TWAS P=7.54e-09 · Best GWAS P=1.12e-12 conditioned to 2.95e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | VDAC2 | 0.07 | 0.07 | lasso | 3 | 0.07 | 5.9e-06 | 6.0 | -5.5 | 5.1e-08 | -0.80 | 0.05 | 0.93 | FALSE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | DUSP13 | 0.04 | 0.02 | lasso | 4 | 0.01 | 1.2e-02 | 5.9 | -5.8 | 7.5e-09 | -0.85 | 0.03 | 0.26 | TRUE |